High-resolution structure of a native DNA-protein crosslink
Read moreTime-resolved crystallography to monitor base excision repair by DNA glycosylases
Read moreHLTF's ancient HIRAN domain binds 3' DNA ends to drive replication fork reversal
Read moreBacterial AlkD is the first glycosylase discovered to repair a bulky lesions like the natural product yatakemycin
Read moreHow do DNA repair enzymes search the genome for chemical damage?
How are stalled replication forks repaired?
SMARCAL1 HARP domain is important for reversal of stalled forks
Read moreHEAT repeats have emerged as an important nucleic acid binding architecture
Base flipping is not a prerequisite for excision repair by DNA glycosylases
Read moreCH-π interactions important for catalysis of base excision by DNA glycosylase AlkD
Read moreCrystals used to determine the atomic structures of a protein-DNA complex
X-ray diffraction image from a protein crystal
Building the atomic structure of a protein-DNA complex into experimental electron density from X-ray diffraction data
NMR chemical shift perturbation to monitor protein structural changes induced by DNA binding
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