Mutiple Sequence Alignment of the Calbindin D28k/Calretinin Subfamily

EF-Hand CaBP Data
Library Sequence Information

Multiple Sequence Alignment of the Calbindin D28k/Calretinin Subfamily

This alignment was generated with CLUSTALW. Please read about how it was constructed to determine if it suit your needs.



CLUSTAL W (1.74) multiple sequence alignment


CABV_MOUSE      -------------------------AESHLQSSLITASQFFEIWLHFDADGSGYLEGKEL
CABV_RAT        -------------------------AESHLQSSLITASQFFEIWLHFDADGSGYLEGKEL
CABV_HUMAN      -------------------------AESHLQSSLITASQFFEIWLHFDADGSGYLEGKEL
CABV_BOVIN      -------------------------AESHLQSSLITASQFFEIWLHFDADGSGYLEGKEL
CABV_CHICK      ------------------------TAETHLQGVEISAAQFFEIWHHYDSDGNGYMDGKEL
CART_HUMAN      -------------------MAGPQQQPPYLHLAELTASQFLEIWKHFDADGNGYIEGKEL
CB32_DROME      MDSAAAAAAKRVQIEKAHNFMRQYRDPESRELKKLSANQFMDVWAHYDKDGNGYIEGTEL
                                              .   ::* **:::* *:* **.**::*.**

CABV_MOUSE      QNLIQELLQARKKAGL--------ELSPEMKSFVDQYGQRDDGKIGIVELAHVLPTEENF
CABV_RAT        QNLIQELLQARKKAGL--------ELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENF
CABV_HUMAN      QNLIQELQQARKKAGL--------ELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENF
CABV_BOVIN      QNLIQELQQARKKAGL--------ELSPEMKTFVDQYGERDDGKIGIVELAHVLPTEENF
CABV_CHICK      QNFIQELQQARKKAGL--------DLTPEMKAFVDQYGKATDGKIGIVELAQVLPTEENF
CART_HUMAN      ENFFQELEKARKGSGMMSKS---DNFGEKMKEFMQKYDKNSDGKIEMAELAQILPTEENF
CB32_DROME      DGFLREFVSSANATDISPEAVTDTMLEELKSCFMEAYDDNQDGKIDIRELAQLLPMEENF
                :.:::*: .: : :.:         :    . *:: *..  **** : ***::** ****

CABV_MOUSE      LLLFRC-QQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVD--DTKLAE
CABV_RAT        LLLFRC-QQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVD--DTKLAE
CABV_HUMAN      LLLFRC-QQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVD--DTKLAE
CABV_BOVIN      LLLFRC-QQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVD--DTKLAE
CABV_CHICK      LLFFRC-QQLKSSEDFMQTWRKYDSDHSGFIDSEELKSFLKDLLQKANKQIE--DSKLTE
CART_HUMAN      LLCFR--QHVGSSAEFMEAWRKYDTDRSGYIEANELKGFLSDLLKKANRPYD--EPKLQE
CB32_DROME      LLLFRFDNPLESSVEFMKIWREYDTDNSGYIEADELKNFLRDLLKEAKKINDVSEDKLIE
                ** **  : : *. :**: **:**:*.**:*:::***.** ***::*::  :  : ** *

CABV_MOUSE      YTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLK--FQGI-KMCGKEFNKAFELYDQDG
CABV_RAT        YTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLK--FQGI-KMCGKEFNKAFELYDQDG
CABV_HUMAN      YTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLK--FQGI-KMCGKEFNKAFELYDQDG
CABV_BOVIN      YTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLK--FQGV-KMCGKEFNKAFELYDQDG
CABV_CHICK      YTEIMLRMFDANNDGKLELTELARLLPVQENFLIK--FQGV-KMCAKEFNKAFEMYDQDG
CART_HUMAN      YTQTILRMFDLNGDGKLGLSEMSRLLPVQENFLLK--FQGM-KLTSEEFNAIFTFYDKDR
CB32_DROME      YTDTMLQVFDANKDGRLQLSEMAKLLPVKENFLCRQVFKGATKLTKEDIEKVFSLYDRDN
                **: :*::** * **:* *:*:::****:**** :  *:*  *:  ::::  * :**:* 

CABV_MOUSE      NGYIDENELDALLKDLCE-KNKQELDINNITTYKKNIM---ALSDGGKLYRTDLALILSA
CABV_RAT        NGYIDENELDALLKDLCE-KNKQELDINNISTYKKNIM---ALSDGGKLYRTDLALILSA
CABV_HUMAN      NGYIDENELDALLKDLCE-KNKQDLDINNITTYKKNIM---ALSDGGKLYRTDLALILCA
CABV_BOVIN      DGYIDENELDALLKDLCE-KNKQDLDINNIPTYKKSIM---ALSDGGKLYRTDLALILSA
CABV_CHICK      NGYIDENELDALLKDLCE-KNKKELDINNLATYKKSIM---ALSDGGKLYRAELALILCA
CART_HUMAN      SGYIDEHELDALLKDLYE-KNKKEINIQQLTNYRKSVM---SLAEAGKLYRKDLEIVLCS
CB32_DROME      SGTIENEELKGFLKDLLELVKKDDYDAQDLAAFEETIMRGVGTDKHGKISRKELTMILLT
                .* *::.**..:**** *  :*.: : :::. :.:.:*   .  . **: * :* ::* :

CABV_MOUSE      GDN-------
CABV_RAT        GDN-------
CABV_HUMAN      GDN-------
CABV_BOVIN      GDN-------
CABV_CHICK      EEN-------
CART_HUMAN      EPPM------
CB32_DROME      LAKISPDDEE

Key: * = perfect match; : = high similarity; . = low similarity

Protein Codes: CABV = calbindin D28k; CART = calretinin; CB32 = calbindin 32k (not yet in the data library)