Mutiple Sequence Alignment of Spectrin Alpha Chains

EF-Hand CaBP Data
Library Sequence Information

Multiple Sequence Alignment of Spectrin Alpha Chains, EF-Hand Containing Region

This alignment was generated with CLUSTALW. Please read about how it was constructed to determine if it suit your needs.



CLUSTAL W (1.74) multiple sequence alignment


SPCN_CHICK      EEALILDNKYTEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTEEALKEFSMMF
SPCN_HUMAN      EEALILDNKYTEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTEEALKEFSMMF
SPCA_DROME      -------------STVGLAQQWDQLDQLSMRMQHNLEQQIQARNHSGVSEDSLKEFSMMF
SPCA_HUMAN      -------------STIGLAQQWDQLYQLGLRMQHNLEQQIQAKDIKGVSEETLKEFSTIY
                             **:********* **.:************:: .**:*::***** ::

SPCN_CHICK      KHFDKDKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDPEFESILDTVDPNRDGHVSLQEYM
SPCN_HUMAN      KHFDKDKSGRLNHQDGKSCLRSLGYDLPMVEEGEPDPEFEAILDTVDPNRDGHVSLQEYM
SPCA_DROME      KHFDKDKSGKLNHQEFKSCLRALGYDLPMVEEGQPDPEFEAILDVVDPNRDGYVSLQEYI
SPCA_HUMAN      KHFDENLTGRLTHKEFRSCLRGLNYYLPMVEEDEHEPKFEKFLDAVDPGRKGYVSLEDYT
                ****:: :*:*.*:: :****.*.* ******.: :*:** :**.***.*.*:***::* 

SPCN_CHICK      AFMISRETENVKSSEEIESAFRALSSERKPYVTKEELYQNLTREQADYCISHMKPYMDGK
SPCN_HUMAN      AFMISRETENVKSSEEIESAFRALSSEGKPYVTKEELYQNLTREQADYCVSHMKPIVDGK
SPCA_DROME      AFMISKETENVQSYEEIENAFRAITAADRPYVTKEELYCNLTKDMADYCVQRMKPFSEPR
SPCA_HUMAN      AFLIDKESENIKSSDEIENAFQAL-AEGKSYITKEDMKQALTPEQVSFCATHMQQYMDPR
                **:*.:*:**::* :***.**:*: :  :.*:***::   ** : ..:*  :*:   : :

SPCN_CHICK      -GRELPSAYDYIEFTRSLFVN
SPCN_HUMAN      -GRELPTAFDYVEFTRSLFVN
SPCA_DROME      SGQPIKDALDYIDFTRTLFQN
SPCA_HUMAN      -VEAISLAMDYVGFTNSYFGN
                  . :  * **: **.: * *

Key: * = perfect match; : = high similarity; . = low similarity

Protein Codes: SPCA = spectrin erythroid isoform alpha chain: SPCN = spectrin non-erythroid (brain) isoform alpha chain