Three possible conformations of EF-hand domains

Conformations of interhelcal interfaces in closed, open, and semi-open EF-hand domains

Analysis of conformational changes associated with calcium-binding to CaM-N

The two intra-EF hand interfaces in the closed to open transition in CaM. There is also a similar black and white picture.

Comparison of the interface between helices II and III in the two apo calmodulin domains, using distance difference matrices and interhelical contacts

Connolly surface for apo and calcium-loaded CaM, with hydrophobic residues highlighted. There is also a similar black and white picture.