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![]() An Introductory Workshop to the Rosetta Protein Modeling Suite
Dates for the next RosettaWorkshop are yet to be announced. If you wish to be informed when registration opens for future workshops, please enter your email below.
ROSETTA SoftwareRosetta is a unified software package for protein structure prediction and functional design. It has been used to predict protein structures with and without the aid of sparse experimental data, perform protein-protein and protein-small molecule docking, design novel proteins and redesign existing proteins for altered function. Rosetta allows for rapid tests of hypotheses in biomedical research which would be impossible or exorbitantly expensive to perform via traditional experimental methods. Thereby, Rosetta methods are becoming increasingly important in the interpretation of biological findings, e.g., from genome projects and in the engineering of therapeutics, probe molecules and model systems in biomedical research (Bender et al. "Protocols for Molecular Modeling with Rosetta3 and RosettaScripts." Biochemistry 2016.)Workshop MaterialsMaterials from previous workshops, including full instructions, example inputs and representative output, can be obtained from the Meiler Lab website. The Rosetta Software itself can be obtained through the RosettaCommons website. The tutorial examples from the workshop have been published in two previous papers in the journal Biochemistry: Bender et al. (2016) "Protocols for Molecular Modeling with Rosetta3 and RosettaScripts." doi:10.1021/acs.biochem.6b00444 and Kaufmann et al. (2010) "Practically useful: what the Rosetta protein modeling suite can do for you." doi:10.1021/bi902153g.
The Rosetta Workshop is hosted by the Meiler Lab at Vanderbilt University, and is supported in part by NIH NIGMS R01 GM073151 ("Rosetta: An Integrated Macromolecular Modeling Suite") and by the RosettaCommons.
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