Nutritional Immunity and Metal Dependent Virulence Factors
Our broad research interests are in understanding the role of metals in modulating protein function. Metals serve critical biological roles as structural stabilizers of proteins, enzymatic cofactors, and signaling messengers. Metalloproteins are predicted to constitute up to one-third of the proteome. We use the tools of structural biology and biochemistry to determine the molecular mechanisms of metalloprotein function with an eye toward understanding the immune response to bacterial pathogens and virulence factors that allow pathogens to sustain and propagate within the host.
All graduate students mentored in the Damo Lab are/were participants in the Fisk-Vanderbilt Mastsers-to-PhD Bridge Program.