CaBP Data Library Structural Information

Range of Entries in N-terminal vs. C-terminal Domain DDMs of Calmodulin and Myosin ELC
helical interface


I/II
 I/III
 I/IV
 II/III
 II/IV
 III/IV
Ca2+-loaded CaM
 most negative entry
(angstroms)
 *
 *
 -1.27
 *
 *
 *
most positive entry
(angstroms)
 2.67
 1.12
 *
 *
 2.45
 1.71
number of significant entries
 23
 4
 2
 0
 29
 17
Apo CaM (1CFC)
 most negative entry
(angstroms)
 -2.77
 -1.18
 -1.67
 -2.33
 -2.06
 -1.85
most positive entry
(angstroms)
 1.82
 4.53
 3.59
 2.85
 4.44
 4.24
number of significant entries
 34
 60
 60
 60
 56
 79
Apo CaM (1DMO)
 most negative entry
(angstroms)
 -3.39
 -1.73
 -2.10
 -1.89
 -3.16
 -2.96
most positive entry
(angstroms)
 1.48
 3.48
 3.84
 3.61
 2.79
 2.91
number of significant entries
 55
 88
 52
 66
 69
 51
ELC
 most negative entry
(angstroms)
 -9.18
 -8.30
 -3.88
 -11.93
 -9.30
 -8.95
most positive entry
(angstroms)
 *
 6.21
 3.50
 5.22
 2.73
 7.62
number of significant entries
 95
 86
 66
 92
 95
 74

This information is supplementary table S2 in:
Nelson, M.R. and W.J. Chazin. An interaction-based analysis of calcium-induced conformational changes in Ca2+ sensor proteins (1998) Protein Sci. 7, 270-282.

* = DDM entry between -1.0 and 1.0 angstroms. Entries in this range are not significantly different from 0.
DDMs were calculated with the DISCOM program.
PDB files used: apo CaM-N, 1CFC and 1DMO; calcium-loaded CaM-N, 1CLL; myosin essential light chain, 1WDC (ELC-N is closed, ELC-C is semi-open).

CaBP Data Library Home Page| General Info| Sequence Info| Structural Info| Analysis Tools
Top of Current Section| Search the Data Library| Site Map| Feedback