Comparison of the N and C terminal domains of apo calmodulin and the myosin essential light chain. a) Superposition of the backbone atoms in the first and fourth helices of the N-terminal (A,D) and C-terminal (E,H) domains of myosin ELC. Contact maps and the DDM show that these two helices have a fairly similar interface in the two domains. The N-terminal domain (dark grey) is in a closed conformation. The C-terminal domain (light grey) is in a semi-open conformation. b) Superposition of the backbone atoms of the first and fourth helices in the N-terminal (A,D) and C-terminal (E,H) domains of calmodulin. The N-terminal domain (dark grey) is in a closed conformation,a s is the C-terminal domain (light grey). All structures were rendered in Insight using PDB coordinates 1WDC (ELC) and 1CFC model #1 (apo CaM).
This figure appeared as figure 14 in the book chapter:
Nelson, M.R., Chazin W.J., "Calmodulin as a calcium sensor" in
Calmodulin and Signal Transduction (1998) L.J. Van Eldik and
D.M. Watterson, eds. Academic Press, San Diego, pp. 17-64.
A color version of this figure is also available.
Details about file locations and color scheme. Internal access only
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