AMBER Archive (2000)

Subject: Re: Protein-Protein docking

From: Simon Cross (pcxsc_at_nottingham.ac.uk)
Date: Tue Oct 31 2000 - 04:02:19 CST


On Mon, 30 Oct 2000, Sam Andersen wrote:

> Hi all,
>
> I am interested in docking two large globular proteins (about 300
> residues each). I know experimental studies that point out few sites
> in either protein domains that "might" be involved in protein-protein
> interactions. Is there any reliable method that returns reasonable
> docked models? I guess DOCK4.0/autodock might be good for small
> ligand-receptor interactions. Experience of people with systems of my
> interest may kindly share their ideas.
>
> Thanks
> Sam
>
>
>
> Get FREE Email/Voicemail with 15MB at Lycos Communications at http://comm.lycos.com
>
The autodock3.0 manual gives an example of protein-protein docking - find
the manual through the Scripps website, A. J. Olson and G. Morris page.

Simon