AMBER Archive (2000)

Subject: Protein-Protein docking

From: Sam Andersen (sam_ccl_at_lycos.com)
Date: Mon Oct 30 2000 - 13:51:40 CST

  Hi all,

  I am interested in docking two large globular proteins (about 300 residues each). I know experimental studies that point out few sites in either protein domains that "might" be involved in protein-protein interactions. Is there any reliable method that returns reasonable docked models? I guess DOCK4.0/autodock might be good for small ligand-receptor interactions. Experience of people with systems of my interest may kindly share their ideas.

  Thanks
   Sam

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