Professional Appointments
- 2005-Present: Professor, Dept. of
Biochemistry, Vanderbilt University, School of Medicine, Nashville,
Tennessee
- 2000-2005: Associate Professor,
Dept. of Biological Sciences/Dept. of Biochemistry, Vanderbilt
University, Nashville, Tennessee
- 1995-2000: Assistant Professor,
Dept. of
Molecular Pharm. & Biological Chem. Member, Drug Discovery Program
and Robert H. Lurie Comprehensive Cancer Center, Northwestern
University Medical School, Chicago, IL.
- 1992-1995: Lecturer and Habilitand,
Laboratory
of Organic Chemistry, Swiss Federal Institute of Technology (ETH),
Zurich, Switzerland
Education
- 1989-1992 Postdoctoral fellow,
Alexander Rich, Dept. of Biology, M.I.T., Cambridge MA, U.S.A.
- 1986-1988 Ph.D Thesis, Laboratory of
Organic Chemistry, ETH-Zurich
- Advisors: Vladimir Prelog (Nobel
laureate, Chemistry, 1975; died 1998),
Jack
D. Dunitz (Prof. emer.), Max Dobler (Prof. emer.)
- 1984 Diploma, Dept. of Chemistry,
ETH-Zurich. Advisor: Jack D. Dunitz
- 1980-1984 Undergraduate, Dept. of
Chemistry, ETH-Zurich
Teaching
2000 - Present:
Classes Taught at Vanderbilt:
- "Protein
design" (Seniors, enrollment 20-30)
- "Introduction
to the biological sciences" (Freshmen, enrollment 200+)
- "RNA structure
and biology" and "X-ray crystallography" (Graduate courses)
1998 - 1999:
Director, Northwestern Drug Discovery Program Summer School.
1995
- Present:
Participated in courses in the Dept of Molec. Pharmac. & Biolog.
Chem, e.g. "Advanced topics in drug discovery" and "Macromolecular
structure and function".
1992
- 1995: Teaching organic synthesis lab course for pharmacology
undergraduate students, ETH-Zurich.
1990:
Instructed sections of an X-ray crystallography course for graduate
students at the Dept. of Biology, M.I.T.
1987
- 1988: Supervisor of chemical crystallography course for under-
graduate students, Laboratory for Organic Chemistry,
ETH-Zurich.
Presentations
- NIEHS Center, Sealy Center for Environmental Health and Medicine, University of Texas Medical Branch, Galveston, TX, March 29, 2010
- Dept. of Chemistry, St. Louis University, St. Louis, MO, February 26, 2010
- Biophysics Program, The Ohio State University, Columbus, OH, January 14, 2010
- Dept. of Chemical Engineering, Laboratory of Biomacromolecular Structure, Polytechnic University of Catalonia, Barcelona, Spain, November 18, 2009
- 67th Annual Pittsburgh Diffraction Society Meeting, RNA Structure, Athens, GA, October 29, 2009.
- INDABA-6, Structure and Properties, Kruger National Park, South Africa, August 30-September 4, 2009.
- American Chemical Society, 238th National Meeting, Division of Carbohydrate Chemistry, RNA Targeting, Nucleic Acids and Analogs, Washington DC, August 18, 2009.
- Dept. of Chemistry, The State University of New York at Binghamton, Binghamton, NY, December 5, 2008.
- Dept. of Drug Discovery, Alnylam Pharmaceuticals Inc., Cambridge, MA, November 11, 2008.
- Dept. of Chemistry, Wake Forest University, Winston-Salem, NC, November 5, 2008.
- Dept. of Chemistry and Biochemistry, Concordia University, Montreal, Quebec, Canada, October 3, 2008.
- American Chemical Society, 236th National Meeting. Philadelphia, PA, Division of Carbohydrate Chemistry, August 19, 2008.
- American Chemical Society, 234th National Meeting,
Protein-Nucleic Acid Interactions: Experimental and Modeling Analysis,
Division of Computers in Chemistry, Boston, MA. August 20, 2007.
- American Chemical Society, 234th National Meeting,
Wolfrom/Isbell/New Investigator Award Symposium, Division of
Carbohydrate Chemistry, Boston, MA. August 19, 2007.
- Dept. of Biochemistry, Baylor College of Medicine, Houston,
TX, May 3, 2007
- Vladimir Prelog Memorial Lecture, The Jubilee XX Croatian
Meeting
of Chemists and Chemical Engineers, Zagreb, Croatia, February 27-March
1, 2007.
- Laboratory of Molecular Biology, Cambridge University,
Cambridge, UK, February 26, 2007.
- INDABA-5, Models, Mysteries and Magic of Molecules, Kruger
National Park, South Africa, August 20-25, 2006.
- Dept. of Biochemistry, University of Pretoria, Pretoria,
South Africa, August 18, 2006.
- First International Conference on Nanobiomedical Technology
and Structural Biology, Chengdu, China, June 25-28, 2006.
- School of Pharmaceutical Sciences, Nottingham University,
Nottingham, UK, May 11, 2006.
- Dept. of Chemistry, Seoul National University, Seoul,
Korea. December 1, 2005.
- The XX Assembly of the International Union of
Crystallography (IUCR Congress). Florence, Italy, August 23-31, 2005
- Dept. of Chemistry, Georgia State University, Atlanta, GA,
April 8, 2005.
- Dept. of Biochemistry, Tufts University, School of
Medicine, Boston, MA, March 17, 2005.
- Dept. of Life Sciences, Proteomics Center, Korea Institute
of Science and Technology, Seoul, Korea, Dec. 27, 2004.
- Dept. of Chemistry, College of Natural Sciences, Seoul
National University, Seoul, Korea, Dec. 21, 2004.
- The Sixth International Meeting on Recognition Studies in
Nucleic Acids (NACON VI). Sheffield, UK, April 4-8, 2004.
- Dept. of Chemistry, Wake Forest University. Winston-Salem,
NC. November 19, 2003.
- RNA Society of North Carolina. North Carolina State
University, Raleigh, NC. November 18, 2003.
- Workshop on "Neutron Macromolecular Crystallography at the
SNS". Argonne National Laboratory, Argonne IL. October 2-3, 2003.
- International Union of Pure and Applied Chemistry (IUPAC)
and
Canadian Society for Chemistry (CSC) Conference. Ottawa, Canada. August
10-15, 2003.
- Albany 2003: The 13th Conversation in Biomolecular
Structure and
Dynamics. The State University of New York, Albany, NY. June 17-21,
2003.
- Nucleic Acids Gordon Conference. Nucleic Acid Modifications
and
Therapeutics Session. Salve Regina University, Newport, RI. June 1-6,
2003.
- American Chemical Society, 225th - National Meeting. New
Orleans, LA. March 23-27, 2003.
- Dept. of Biochemistry, Vanderbilt University Medical
School. Nashville, TN. November 4, 2002.
- Dept. of Biochemistry, Tufts University Medical School.
Boston, MA. October 8, 2002.
- Dept. of Biology, MIT, Macromolecular Structure &
Function Seminar. Cambridge, MA. October 7, 2002.
- The Seventh International Meeting on RNase H Chemistry and
Biology. Tsuruoka, Japan. September 25-28. 2002.
- The XIX Assembly of the International Union of
Crystallography (IUCR Congress). Geneva, Switzerland. August 6-15, 2002.
- European Symposium on Bio-Organic Chemistry. Gregynog,
Powys, Wales, UK. May 10-13, 2002.
- Dept. of Chemistry, Brooklyn College (CUNY), Brooklyn, NY.
September 28, 2001.
- The Fifth International Meeting on Recognition Studies in
Nucleic Acids (NACON V). Sheffield, UK, April 9-12, 2001.
- The 2000 International Chemical Congress of Pacific Basin
Societies. Honolulu, Hawaii. December 14-19, 2000.
- International Symposium on the Development of New
Structural Biology Including Hydrogen Bonding and Hydration. Mito,
Ibaraki, Japan. October 27-29, 2000.
- RNA structure meeting, University of California at Santa
Cruz. Santa Cruz, CA. July 12-16, 2000.
- European Symposium on Bioorganic Chemistry. Gregynog,
Powys, Wales, UK. May 12-15, 2000.
- Dept. of Biology, Massachusetts Institute of Technology.
Cambridge, MA. May 1, 2000.
- Dept. of Biological, Chemical and Physical Sciences,
Illinois Institute of Technology. Chicago, IL. April 24, 2000.
- Robert H. Lurie Cancer Center Seminar Series, Northwestern
University. Chicago, IL. January 5, 2000.
- School of Chemistry, University of Birmingham, Birmingham,
UK. October 12, 1999.
- American Chemical Society, 218th National Meeting,
New Orleans, LA. August 25, 1999.
- Gordon Research Conference, Purines, Pyrimidines and
Related Substances, Salve Regina University, Newport, RI. July 4-9,
1999.
- Dept. of Biology, M.I.T., Cambridge, MA. May 9, 1999.
- Dept. of Molecular Biology, Vanderbilt University,
Nashville, TN. May 6, 1999.
- International Summer School, Nucleic Acid Chemistry,
University of Copenhagen, Denmark. June 4 — 9, 1999.
- Merck Basic Research Center (IRBM P. Angeletti), Rome,
Italy. March 22, 1999.
- Dept. of Biochemistry, Center for Toxicology, Vanderbilt
University School of Medicine, Nashville, TN. February 24, 1999.
- International Carbohydrate Symposium, University of
California San Diego, CA. August 10, 1998.
- Dept. of Biology, Northern Illinois University, DeKalb, IL.
March 27, 1998.
- Second NIH Symposium on Therapeutic Oligonucleotides: Targeting
Transcription Factors and Signaling Pathways, Washington, D.C.
December 5, 1997.
- 55th Pittsburgh Diffraction Conference, Athens, GA.
November 6 - 8, 1997.
- Dept. of Chemistry, Georgia State University, Atlanta, GA.
November 5, 1997.
- 38th International Symposium on: Regulation of Enzyme
Activity and Synthesis in Normal and Neoplastic Tissues, University
of Indiana Medical School, Indianapolis. September 29 - 30, 1997.
- 4th Cambridge Symposium on: Oligonucleotide Chemistry
& Biology, Queens' College, Cambridge, U.K. August 31 -
September 3, 1997.
- Laboratory for Medicinal Chemistry, National Institutes of
Health, National Cancer Center, Bethesda, MD. March 17, 1997.
- Depts. of Biochemistry & Molecular Biology and
Chemistry, The University of Chicago, Chicago, IL,. December 12, 1996.
- Vienna Biocenter, University of Vienna, Vienna, Austria.
October 31, 1996.
- Dept. of Chemistry, Tufts University, Medford, MA. October
22, 1996.
- Hoffmann-La Roche Symposium: Novel Synthetic Methods
1996, Gersau, Lake Lucerne, Switzerland. September 15 - 18, 1996.
- Intl. Union of Crystallography XVII and American
Crystallographic Association (ACA) Congress and General Assembly,
Seattle, WA. August 8 - 17, 1996.
- First Annual Meeting of the RNA Society, University
of Madison, WI. May 29, 1996.
- Colloquium RNA Biochemistry, Assembly of the study
section
members and supported researchers within the DFG (German Natl. Science
Foundation), Bamberg, Germany. May 20, 1996.
- Boston Area RNA Meeting, M.I.T. April 1, 1996.
- Central Research Laboratories, CIBA Ltd., Basel,
Switzerland. September, 1995.
- Colloquium RNA Biochemistry, Assembly of the study
section
members and supported researchers within the DFG (German Natl. Science
Foundation), Bayreuth, Germany. April 4, 1995.
- Ribozyme Pharmaceuticals Inc. (RPI), Boulder, CO. March 24,
1995.
- Dept. of Molecular Pharmacology and Biological Chemistry,
Northwestern University Medical School, Chicago, IL. March 20, 1995.
Society
Memberships
- American Association for the
Advancement of Science (AAAS)
- American Biophysical Society
- American Chemical Society (ACS)
- American Crystallographic Association
(ACA)
- Intl. Society for the Study of the
Origin of Life (ISSOL)
- Intl. Society for Nucleosides,
Nucleotides and Nucleic Acids (IS3NA)
- New Swiss Chemical Society (NSCG)
- Sigma Psi Society (M.I.T. Chapter)
- Swiss Crystallographic Society (SKG)
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