CSB NMR Facility
Biomolecular NMR Facility
900 MHz NMR Spectrometer at Vanderbilt
The Biomolecular NMR Facility at Vanderbilt received their 900MHz NMR spectrometer on May 7th 2011..
What is Biomolecular NMR?
Nuclear Magnetic Resonance spectroscopy (NMR) is a powerful technique that can
provide information on molecular structure and dynamics at the atomic level.
The naturally-occuring 1H isotope is the most sensitive NMR reporter.
However, the very large number of 1H nuclei in macromolecules, can make the
1H-NMR spectrum intractable. Fortunately, with the advent of multi-dimensional
techniques and methods in molecular biology to incorporate 13C, 15N and 2H
in biological macromolecules, it has become possible to probe the structure, dynamics
and biochemistry of proteins, RNA, DNA, and carbohydrates with NMR.
The Vanderbilt Biomolecular NMR center was created as a part of a transinstitutional
initiative to develop structural biology on campus.