Program for Friday June 20, 2008 - Peabody Commons

12:00-2:00 Check-in Commons Main Entrance

2:00-2:20 Opening Remarks

Location: Peabody Commons Dining Center (Lecture Hall)

NMR and X-ray I Chair: Jie Zheng
2:20-2:40pm R.W. Kriwacki
St. Jude Children's Research Hospital		 How PUMA Attacks Its Prey: Understanding the Molecular Basis of PUMA-Induced Cell Death
2:40-3:00pm Chris Brosey
Vanderbilt University		 RPA Quaternary Remodeling: Insights into a DNA-Processing Machine
3:00-3:20pm Yuefeng Wang
St. Jude Children's Research Hospital		 p27Kip1 Phosphorylation, Degradation and Cancer
3:20-3:40pm Break
NMR and X-ray II Chair: Brandt Eichman
3:40-4:00pm Emily Rubinson
Vanderbilt University		 A New Protein Architecture for Processing Alkylation Damaged DNA: The Crystal Structure of DNA Glycosylase AlkD
4:00-4:20pm Ho-Jin Lee
St. Jude Children's Research Hospital		 The C-terminus of Dishevelled folds back to its own PDZ domain: Implication of inactive state of Dishevelled
4:20-4:40pm Seth Albright
The University of Tennessee, Knoxville		 Solution NMR studies provide structural basis for endotoxin pattern recognition by the innate immune receptor CD14
4:40-5:00pm Break
Keynote Address
5:00-6:00pm Jens Meiler
Vanderbilt University		 The (inverse) protein folding problem -- state-of-the art in computational protein folding and design
Poster Session and Reception
6:15-8:15pm Stambaugh Hall
Dinner
8:15-9:15pm Peabody Commons Dining Hall

Program for Saturday June 21, 2008 - Peabody Commons

Breakfast
7:00-8:20am Peabody Commons Dining Hall
Computational Structural Biology Chair: Jens Meiler
8:20-8:40am Ralf Mueller
Vanderbilt University		 Virtual High Throughput Screening for mGluR5 potentiators
8:40-9:00am Nils Woetzel
Vanderbilt University		 Knowledge based energy functions assist in ab initio protein structure prediction
9:00-9:20am Pavan Ghatty
Oak Ridge National Laboratory		 Effect of temperature and concentration of glycerol-water binary mixtures on the dynamics of proteins
9:20-9:40am Xuelin Wang
St. Jude Children's Research Hospital		 Computational Studies of Drug Resistance of H5N1 Influenza Viruses to Oseltamivir
9:40-10:00am Katherine Ayers
St. Jude Children's Research Hospital		 Structure-Based Development of Novel Dihydropteroate Synthase Inhibitors
10:00-10:20am Break
Complementary Structural Methods Chair: Engin Serpersu
10:20-10:40am Steffen Lindert
Vanderbilt University		 Cryo-EM guided de novo Protein Fold Elucidation
10:40-11:00am Nathan Alexander
Vanderbilt University		 De novo high-resolution protein structure determination from sparse spin-labeling EPR data
11:00-11:20am Adrianne L. Norris
The University of Tennessee, Knoxville		 Hydrogen-Deuterium Exchange Studies of a 30 kDa Antibiotic Resistance Conferring Enzyme
11:20-11:40am Balananda Durjati Putcha
The University of Tennessee, Knoxville		 Allosteric interplay in Thyroid hormone receptor transactivation
Closing Remarks
11:40-12:00pm Stephen White
St. Jude Children's Research Hospital
Lunch
12:00-1:00pm Peabody Commons Dining Hall