Jonathan H. Sheehan Ph.D.

I have moved - August 2019

My new position is at Washington University Medical School in St. Louis (WUSTL).
My current website is here:
I still have an adjoint appointment at Vanderbilt.

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Vanderbilt Center for Structural Biology
PMB 407917
465 21st Ave S, 5140 MRB3
Nashville, TN 37240-7917
615-936-2211 (fax)

picture of Jonathan H Sheehan around 1999

I am a Research Associate Professor performing computational outreach services for Vanderbilt's Center for Structural Biology. My primary research interests lie in protein and DNA modeling and simulation. I have developed collaborations with many investigators at Vanderbilt to apply these techniques to a wide variety of research problems. I also teach classes and workshops, and provide one-on-one training in biomolecular visualization, macromolecular modeling, structure prediction, computational mutation analysis, docking, and simulation.

I earned my Ph.D. in the lab of Walter Chazin, as a molecular biophysics trainee in the structural biology center, studying calcium-binding proteins via NMR, toward a degree in biochemistry. My dissertation was titled "Probing functional diversity of EF-hand calcium-binding proteins through mutant design and structural analysis".

Before starting graduate school, I worked as a technician for ten years, studying antigen presentation to cytotoxic T lymphocytes, then using mouse embryonic stem cells to study pancreas development in diabetes, and eventually running Vanderbilt's Cell Imaging Core Lab.

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Brief Bio:

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