Monomer psi psi psi Psi Psi Psi Psi Psi Psi Psi Psi Psi Psi Psi Psi Psi Psi Psi Psi Psi Psi Psi Psi Psi Psi Psi Psi Psi
Spec1 torsion torsion circular Torsion Torsion Torsion Torsion Torsion Torsion Torsion Torsion Torsion Torsion Torsion Torsion Torsion Torsion Torsion Torsion Torsion Torsion Torsion Torsion Torsion Torsion Torsion Torsion Torsion
BAX1 min_value max_value variance BAX1 BAX2 BAX3 BAX4 BAX5 BAX6 BAX7 BAX8 BAX9 BAX10 BAX11 BAX12 BAX13 BAX14 BAX15 BAX16 BAX17 BAX18 BAX19 BAX20 BAX21 BAX22 BAX23 BAX24 BAX25
ALA_1 -169.3 176.3 0.4846 -100.2 -94.5 82.2 116.4 -81.0 -163.5 -161.3 90.3 89.2 -162.0 -142.5 166.1 -113.6 170.5 151.2 176.3 98.1 89.4 -78.7 158.3 89.2 156.9 -161.0 132.4 -169.3
ASP_2 14.4 22.9 0.001 17.6 16.5 22.9 14.8 17.9 15.1 17.1 19.5 15.8 14.6 16.4 14.9 19.0 19.1 16.2 22.1 19.7 14.4 21.4 17.6 22.7 18.2 18.7 20.3 20.9
GLN_3 17.1 151.6 0.0662 147.9 148.2 148.5 143.8 147.4 149.2 148.0 148.2 151.6 149.2 149.8 149.2 148.3 17.1 147.3 148.7 147.7 149.2 149.5 147.0 147.9 150.7 144.7 148.5 147.7
LEU_4 108.2 151.6 0.0135 123.1 137.3 138.3 119.5 130.7 111.8 125.6 121.2 132.4 108.2 112.4 121.3 131.0 128.5 125.7 127.2 130.1 118.6 134.0 130.5 141.2 122.5 122.2 130.5 151.6
THR_5 150.7 164.4 0.0017 160.2 156.0 157.6 154.2 154.0 157.3 159.9 159.8 163.9 162.1 158.9 155.2 162.8 159.8 159.9 152.5 157.3 164.4 156.7 156.6 150.7 157.4 160.2 157.0 157.5
GLU_6 -44.0 -23.3 0.0034 -29.4 -44.0 -34.5 -34.2 -29.0 -30.4 -33.6 -35.3 -42.7 -30.2 -26.0 -27.5 -39.2 -31.6 -33.4 -30.1 -39.8 -29.9 -34.2 -33.5 -31.5 -33.9 -23.3 -35.1 -32.4
GLU_7 -57.6 -41.6 0.0023 -53.1 -47.3 -51.9 -52.5 -51.2 -57.3 -47.8 -45.1 -49.9 -49.3 -57.6 -49.7 -45.9 -41.6 -52.5 -48.6 -45.9 -47.2 -45.4 -45.8 -49.1 -52.6 -49.9 -54.3 -55.0
GLN_8 -40.1 -35.2 0.0002 -36.8 -40.1 -37.8 -36.8 -37.6 -35.2 -38.5 -37.6 -37.2 -37.7 -35.2 -35.8 -38.3 -39.3 -38.0 -36.5 -38.2 -36.9 -37.9 -37.6 -38.2 -37.9 -36.8 -38.2 -38.3
ILE_9 -39.6 -32.8 0.0005 -35.7 -37.0 -35.9 -37.1 -35.6 -37.2 -34.6 -35.5 -37.2 -37.5 -36.6 -39.6 -32.8 -36.0 -34.6 -34.3 -38.6 -34.4 -37.9 -34.2 -33.7 -34.1 -33.5 -36.0 -38.7
ALA_10 -48.8 -19.0 0.0144 -46.8 -32.2 -44.5 -19.0 -47.0 -25.3 -36.6 -43.9 -43.5 -34.1 -44.1 -21.2 -46.5 -48.8 -43.1 -42.2 -23.5 -47.4 -27.3 -48.8 -48.1 -46.6 -48.1 -46.2 -25.9
GLU_11 -54.7 -32.1 0.0056 -47.2 -48.6 -50.2 -53.4 -50.1 -48.2 -32.4 -51.2 -32.1 -50.4 -45.3 -51.4 -44.1 -49.4 -54.3 -54.7 -53.8 -44.4 -44.3 -33.6 -47.7 -47.6 -48.0 -46.2 -43.8
PHE_12 -38.1 -24.9 0.0023 -28.9 -28.7 -26.6 -34.7 -32.5 -35.9 -38.1 -31.5 -37.1 -29.2 -33.8 -34.2 -34.5 -28.4 -27.3 -36.6 -26.4 -35.6 -37.0 -36.5 -32.2 -28.4 -35.2 -24.9 -34.9
LYS_13 -52.9 -34.3 0.0028 -41.0 -49.9 -42.3 -47.5 -43.0 -48.4 -34.3 -41.7 -37.8 -49.7 -40.1 -49.1 -43.4 -41.6 -44.2 -51.8 -52.9 -43.1 -47.9 -43.2 -43.3 -42.3 -43.9 -40.9 -44.3
GLU_14 -57.3 -41.6 0.0028 -45.4 -45.2 -45.9 -56.9 -49.8 -53.2 -51.4 -52.8 -51.0 -44.1 -54.4 -57.3 -46.2 -41.7 -45.6 -45.7 -47.4 -45.7 -49.1 -45.2 -41.6 -46.3 -44.2 -43.8 -50.7
ALA_15 -33.5 -25.3 0.001 -30.5 -32.1 -32.8 -31.9 -27.2 -31.7 -28.3 -32.3 -29.9 -32.7 -30.9 -31.9 -28.6 -30.4 -27.7 -25.3 -30.0 -26.5 -26.8 -27.2 -27.1 -33.5 -25.4 -26.3 -31.1
PHE_16 -52.9 -33.7 0.0026 -35.8 -42.4 -37.7 -42.3 -44.2 -43.2 -44.6 -40.6 -40.1 -33.7 -43.6 -37.4 -44.8 -43.9 -43.1 -52.9 -44.7 -49.1 -44.5 -47.0 -43.1 -42.9 -47.7 -48.2 -42.2
SER_17 -33.7 -15.5 0.0051 -32.7 -32.3 -33.7 -31.8 -17.6 -30.5 -15.5 -33.5 -31.0 -32.5 -21.3 -31.3 -22.8 -19.8 -19.7 -21.7 -30.9 -22.3 -31.0 -31.4 -21.5 -30.4 -22.6 -30.2 -33.4
LEU_18 -28.1 -18.6 0.001 -26.2 -20.9 -23.2 -19.7 -25.4 -20.7 -28.1 -21.5 -24.3 -25.1 -20.6 -26.2 -20.2 -20.8 -21.4 -18.9 -20.8 -18.7 -22.5 -20.5 -22.3 -20.4 -18.6 -20.3 -24.6
PHE_19 13.7 29.9 0.0016 20.0 20.2 22.0 22.4 17.5 19.6 26.4 21.4 29.9 18.9 24.0 20.1 20.3 22.6 20.6 20.3 25.2 21.1 22.3 23.7 24.9 13.7 24.2 22.2 26.5
ASP_20 67.5 70.3 0.0001 69.5 69.7 69.9 68.9 68.9 69.7 68.8 69.0 69.8 69.5 67.9 69.8 69.4 69.2 69.6 69.6 69.6 68.8 70.3 69.5 69.7 68.8 69.8 67.5 70.3
LYS_21 -4.3 4.7 0.0007 0.9 -2.0 2.0 -2.0 1.7 0.5 -1.7 2.6 -2.0 4.7 -2.2 1.0 -4.3 2.1 1.5 -2.2 -4.2 -0.2 -0.7 2.8 0.5 -1.7 -2.2 -1.5 -0.5
ASP_22 0.1 6.5 0.0003 3.9 2.5 2.8 2.8 6.5 4.5 2.7 3.3 0.1 4.7 1.9 4.5 0.9 2.9 4.5 3.7 1.1 3.4 3.8 2.5 2.4 4.4 1.5 3.0 1.9
GLY_23 13.1 24.6 0.0015 18.4 19.4 14.0 18.1 22.0 19.8 18.4 15.1 14.8 13.1 18.9 16.4 23.4 16.6 20.3 23.5 20.7 19.6 16.7 13.7 15.8 24.6 20.6 21.2 15.5
ASP_24 -4.7 5.1 0.001 1.2 3.7 -1.0 1.2 -1.7 0.5 -2.1 4.4 3.9 -4.7 0.1 0.3 -2.9 -0.9 -0.8 -0.8 5.1 0.1 -2.6 -0.8 1.9 -4.1 4.1 2.2 1.8
GLY_25 23.9 31.8 0.0005 26.3 28.7 30.7 29.4 28.0 28.3 28.5 30.4 30.5 31.8 28.8 31.0 26.7 28.5 27.9 25.3 26.8 28.2 29.1 30.7 29.5 23.9 27.2 26.0 29.1
THR_26 165.9 168.8 0.0001 167.4 167.3 166.1 168.3 167.1 167.7 166.9 167.7 166.6 166.8 166.5 167.3 166.0 165.9 168.5 168.1 168.6 166.6 168.0 168.8 168.2 165.9 167.2 168.1 166.9
ILE_27 160.1 169.5 0.0008 163.1 162.5 162.6 165.9 160.1 167.7 163.3 167.2 163.2 165.1 162.4 165.4 166.2 167.6 164.0 169.5 168.3 164.9 167.7 168.4 166.8 166.4 163.8 162.5 165.0
THR_28 163.2 169.0 0.0003 167.2 163.2 165.1 163.9 165.7 166.2 167.1 168.1 167.3 166.8 167.4 166.4 166.7 169.0 167.7 165.1 167.5 166.0 168.3 163.9 167.2 165.8 167.2 165.9 168.0
THR_29 -34.1 -26.7 0.0004 -29.9 -31.3 -31.2 -29.1 -29.7 -30.3 -30.1 -29.3 -29.7 -30.2 -34.1 -27.6 -31.0 -32.2 -30.3 -29.4 -31.0 -29.9 -29.0 -26.7 -28.5 -30.3 -28.6 -33.2 -29.8
LYS_30 -28.6 -23.8 0.0003 -24.8 -27.9 -27.3 -27.0 -27.6 -23.8 -27.3 -25.2 -27.6 -25.1 -27.2 -24.1 -25.8 -28.6 -26.0 -27.0 -25.2 -26.1 -24.6 -25.9 -24.1 -27.3 -26.7 -26.7 -26.5
GLU_31 -1.3 15.7 0.0032 13.0 11.7 11.7 13.2 11.6 11.8 11.6 13.5 1.6 13.5 5.8 9.7 3.3 6.7 11.2 12.4 -1.1 11.8 7.9 15.7 13.1 6.9 -1.3 6.7 12.1
LEU_32 -53.1 -49.4 0.0002 -51.6 -49.6 -50.2 -50.2 -51.3 -50.6 -49.8 -50.5 -52.8 -49.7 -49.8 -50.1 -51.3 -49.4 -53.1 -49.9 -50.9 -51.0 -51.8 -50.3 -52.9 -49.7 -50.2 -50.4 -50.2
GLY_33 -33.9 -21.5 0.0011 -25.2 -33.9 -26.7 -23.2 -21.5 -26.9 -25.7 -24.1 -26.3 -24.4 -24.5 -23.1 -31.4 -25.1 -26.8 -28.9 -25.1 -25.8 -26.1 -26.6 -29.3 -25.1 -27.6 -29.4 -22.6
THR_34 -42.7 -39.5 0.0001 -41.3 -41.3 -40.9 -40.2 -41.3 -42.1 -42.3 -42.0 -42.5 -42.0 -42.6 -42.3 -39.5 -41.6 -41.1 -42.2 -41.3 -41.0 -41.5 -40.9 -41.1 -42.3 -42.7 -40.4 -41.5
VAL_35 -54.2 -43.8 0.0007 -43.8 -46.5 -50.3 -48.8 -47.5 -48.8 -47.6 -47.5 -51.9 -46.6 -48.7 -49.9 -50.2 -46.2 -47.7 -50.5 -48.7 -50.2 -49.3 -50.3 -51.6 -46.8 -54.2 -52.4 -49.4
MET_36 -40.3 -29.9 0.0011 -38.3 -34.8 -35.8 -34.2 -32.9 -37.3 -40.3 -31.7 -35.1 -38.6 -36.9 -37.0 -37.6 -39.3 -38.6 -34.9 -33.9 -35.4 -36.2 -30.3 -29.9 -38.3 -38.2 -32.4 -35.4
ARG_37 -38.5 -22.9 0.0026 -27.3 -28.9 -28.7 -36.1 -31.1 -31.4 -23.1 -38.5 -32.7 -29.8 -31.3 -37.0 -36.8 -26.2 -34.3 -34.4 -28.5 -34.9 -34.4 -33.7 -34.9 -22.9 -28.7 -31.4 -26.5
SER_38 -41.7 -24.7 0.0017 -33.5 -27.8 -33.3 -35.6 -33.2 -27.9 -36.2 -34.8 -31.0 -33.5 -30.0 -30.8 -41.7 -28.8 -33.0 -31.8 -33.1 -32.6 -34.9 -30.3 -34.0 -35.6 -24.7 -34.9 -33.2
LEU_39 -1.2 4.3 0.0004 0.7 0.0 0.6 -0.8 -0.7 0.6 3.6 1.4 -0.7 2.7 0.6 2.0 0.2 0.4 4.3 -1.0 1.7 -1.2 1.2 -0.5 -0.9 3.9 0.8 1.3 2.0
GLY_40 12.5 23.5 0.0009 17.4 17.5 18.6 17.2 22.7 15.8 21.7 17.2 18.3 15.7 16.5 18.9 18.2 17.5 16.8 17.1 18.6 12.5 15.7 15.2 23.5 19.7 15.9 17.1 21.5
GLN_41 139.7 152.8 0.0018 142.6 147.6 143.3 139.7 143.9 144.1 142.7 141.4 144.5 142.8 148.6 142.0 141.3 152.7 140.1 152.8 142.7 140.8 143.2 142.1 140.0 145.1 146.1 143.9 139.9
ASN_42 73.0 75.6 0.0001 74.1 73.6 74.1 74.5 74.6 74.5 74.0 74.4 74.1 75.6 73.0 73.9 74.0 75.1 74.4 73.7 74.0 73.6 75.3 74.5 75.0 74.6 73.4 74.1 74.3
PRO_43 144.5 155.0 0.0009 148.2 144.5 151.7 153.0 150.0 149.7 149.3 152.0 150.4 149.3 145.9 152.2 150.7 146.5 151.5 145.9 149.7 151.8 151.1 151.9 155.0 147.4 147.7 151.1 151.4
THR_44 166.3 177.2 0.0016 169.7 171.6 168.1 172.5 172.6 176.1 174.2 169.2 170.4 172.7 173.5 175.5 171.7 172.8 167.6 177.2 166.7 166.3 173.7 174.5 175.9 173.1 166.5 174.1 176.7
GLU_45 -47.2 -32.3 0.0015 -38.1 -42.4 -40.1 -47.2 -43.2 -42.5 -43.8 -45.4 -38.2 -34.1 -32.3 -40.2 -42.5 -41.2 -38.4 -41.9 -38.6 -39.4 -40.3 -38.7 -41.6 -42.5 -43.3 -40.1 -42.5
ALA_46 -41.3 -35.9 0.0003 -39.6 -39.7 -35.9 -36.7 -39.0 -38.0 -40.0 -38.1 -40.5 -39.9 -37.9 -40.9 -38.0 -36.6 -40.0 -37.3 -41.3 -40.8 -39.7 -39.9 -39.9 -39.3 -38.3 -39.6 -38.1
GLU_47 -40.8 -35.1 0.0003 -39.1 -39.1 -39.5 -40.3 -39.6 -39.1 -37.9 -39.8 -37.4 -36.4 -38.1 -37.2 -36.4 -38.1 -37.6 -37.9 -35.1 -36.7 -37.4 -36.6 -37.9 -39.1 -40.8 -38.6 -38.3
LEU_48 -53.5 -44.0 0.0008 -47.3 -46.6 -49.3 -53.5 -45.9 -45.7 -44.7 -47.6 -47.0 -48.6 -48.7 -44.5 -45.1 -46.1 -49.0 -50.7 -46.0 -46.9 -45.0 -44.7 -48.6 -45.4 -49.7 -45.7 -44.0
GLN_49 -28.5 -20.5 0.0004 -23.1 -23.3 -22.5 -20.9 -23.0 -24.0 -23.1 -21.9 -21.6 -21.4 -22.6 -20.5 -22.0 -23.1 -22.5 -25.8 -23.3 -23.5 -23.9 -21.4 -28.5 -22.1 -20.9 -22.5 -21.9
ASP_50 -56.5 -42.5 0.0012 -48.4 -45.3 -49.0 -49.5 -47.8 -42.8 -42.5 -45.0 -48.0 -46.5 -47.3 -46.8 -49.6 -45.6 -46.7 -47.1 -44.7 -50.3 -44.6 -45.8 -44.8 -46.2 -56.5 -45.6 -48.9
MET_51 -38.9 -26.5 0.0017 -33.4 -37.2 -34.5 -33.8 -38.8 -33.6 -38.9 -33.8 -27.9 -30.0 -33.8 -28.9 -27.3 -31.4 -31.5 -32.9 -29.4 -28.7 -32.5 -29.6 -29.7 -28.6 -28.7 -31.2 -26.5
ILE_52 -47.2 -37.1 0.0012 -42.6 -45.5 -45.8 -44.7 -46.8 -37.5 -47.2 -38.5 -41.5 -37.1 -44.7 -39.9 -39.9 -43.5 -40.1 -42.6 -44.9 -38.9 -43.8 -40.6 -40.0 -42.9 -40.5 -42.8 -42.7
ASN_53 -56.9 -27.8 0.0119 -34.1 -30.0 -28.4 -31.1 -28.7 -56.2 -27.8 -56.2 -30.4 -56.9 -30.5 -32.2 -35.6 -33.5 -54.9 -35.3 -34.5 -40.0 -35.2 -32.4 -36.3 -33.5 -35.5 -33.1 -37.3
GLU_54 -59.2 -30.2 0.0086 -43.1 -51.3 -57.7 -57.2 -53.0 -30.2 -52.3 -31.3 -51.5 -31.1 -59.2 -49.7 -48.3 -54.4 -48.7 -50.2 -52.0 -49.7 -53.7 -50.0 -50.9 -51.8 -50.7 -49.4 -54.4
VAL_55 -31.8 -25.2 0.0005 -25.5 -28.7 -25.4 -25.2 -25.4 -29.4 -25.6 -28.3 -29.4 -27.8 -28.6 -25.8 -27.5 -29.7 -26.7 -27.2 -28.2 -30.9 -29.7 -25.5 -28.3 -29.4 -31.8 -28.2 -26.3
ASP_56 31.2 42.3 0.0011 33.4 37.7 33.8 36.1 34.2 37.7 31.2 39.0 39.4 38.9 38.9 36.8 37.9 39.3 35.5 37.0 35.8 42.3 38.4 33.6 40.2 39.6 42.0 37.6 36.1
ALA_57 -32.5 -16.2 0.0028 -25.5 -25.6 -27.4 -21.5 -26.3 -18.7 -23.6 -28.9 -21.7 -19.9 -20.5 -32.5 -20.8 -23.0 -16.2 -19.0 -30.8 -23.7 -18.8 -30.3 -17.3 -20.0 -20.0 -22.8 -22.8
ASP_58 -19.3 -18.6 0.0 -18.9 -18.8 -18.7 -19.1 -18.7 -19.2 -18.8 -19.3 -19.0 -19.1 -18.8 -18.8 -19.1 -19.0 -19.1 -19.1 -18.6 -19.0 -19.2 -18.8 -19.2 -19.1 -19.1 -18.8 -19.1
GLY_59 5.1 45.2 0.023 21.1 44.5 26.8 41.1 29.4 6.9 45.2 19.9 42.6 5.1 41.9 30.9 24.3 42.1 7.4 29.9 26.6 17.1 16.8 22.1 17.3 42.5 20.5 18.5 12.0
ASN_60 -92.3 14.6 0.2619 1.5 -91.9 -50.2 -91.9 -58.6 1.2 -91.4 3.1 -92.1 2.3 -92.2 3.4 9.4 -92.3 6.6 14.6 2.6 -0.7 6.6 1.7 8.1 -91.7 4.5 -43.9 3.4
GLY_61 19.7 52.9 0.0145 29.3 51.4 40.2 52.0 42.4 36.0 51.2 26.9 49.4 35.2 51.8 19.7 31.2 52.6 35.1 30.3 24.9 32.8 29.5 33.6 30.3 52.9 31.0 39.3 35.9
THR_62 159.8 174.1 0.0032 169.7 163.0 165.8 161.1 161.2 174.1 162.7 170.7 160.9 170.7 162.1 168.3 172.3 160.0 172.2 168.9 172.8 169.9 172.3 166.6 171.8 159.8 168.6 168.3 170.4
ILE_63 134.0 138.3 0.0002 136.3 134.3 134.7 136.6 135.0 137.3 134.0 137.3 135.6 134.7 135.9 138.1 137.3 136.9 136.0 138.3 137.4 138.3 136.8 136.8 136.8 136.4 136.8 137.4 134.7
ASP_64 163.3 167.3 0.0001 166.3 166.4 165.2 166.2 164.9 166.0 166.1 163.3 167.2 166.2 165.5 164.1 166.5 165.1 164.8 165.6 164.8 166.2 166.4 166.4 167.3 165.9 165.3 165.7 165.3
PHE_65 -45.7 -42.9 0.0001 -43.5 -43.7 -45.7 -44.5 -45.3 -43.3 -43.8 -44.9 -43.9 -45.3 -44.4 -44.8 -42.9 -45.3 -45.0 -44.0 -45.5 -44.3 -43.3 -43.7 -42.9 -45.1 -44.1 -45.0 -44.6
PRO_66 -55.1 -47.6 0.0005 -52.9 -50.9 -53.1 -51.0 -52.6 -52.0 -52.4 -51.3 -51.4 -54.3 -49.4 -52.1 -49.0 -54.3 -53.1 -50.7 -51.2 -52.3 -47.6 -49.9 -50.0 -54.9 -51.4 -51.8 -55.1
GLU_67 -33.1 -30.8 0.0001 -31.4 -31.4 -31.7 -31.8 -32.5 -32.8 -32.1 -32.9 -30.8 -32.8 -32.3 -32.3 -31.8 -32.3 -32.0 -32.8 -30.9 -31.2 -33.0 -32.7 -31.4 -31.4 -31.7 -31.0 -33.1
PHE_68 -37.9 -34.9 0.0001 -37.0 -36.6 -36.9 -36.5 -35.7 -35.7 -37.4 -35.9 -37.1 -35.9 -36.9 -35.6 -35.1 -37.9 -34.9 -35.4 -36.7 -36.9 -35.3 -36.1 -36.2 -37.3 -35.5 -36.2 -36.1
LEU_69 -28.7 -23.9 0.0002 -24.4 -26.7 -25.3 -25.4 -25.5 -27.6 -25.5 -25.4 -25.0 -26.1 -25.6 -26.7 -25.5 -25.4 -25.8 -25.7 -28.7 -25.6 -26.3 -25.7 -23.9 -26.9 -25.7 -27.7 -27.2
THR_70 -39.4 -21.4 0.005 -21.4 -26.0 -26.0 -23.9 -26.6 -27.7 -26.7 -27.9 -37.0 -21.5 -21.9 -38.7 -38.0 -26.5 -24.6 -35.2 -30.9 -35.6 -39.4 -34.9 -35.9 -26.2 -36.4 -32.4 -32.9
MET_71 -49.7 -31.2 0.0054 -46.1 -45.7 -47.4 -46.7 -44.4 -42.6 -46.0 -48.8 -32.9 -47.4 -49.7 -33.6 -31.2 -45.9 -46.4 -34.9 -45.6 -31.2 -36.7 -39.0 -36.1 -45.4 -33.7 -43.6 -42.8
MET_72 -41.2 -30.6 0.0013 -32.8 -33.3 -33.8 -33.8 -36.6 -34.6 -36.4 -32.5 -39.6 -30.6 -33.0 -40.1 -41.2 -34.5 -31.8 -38.6 -33.3 -39.6 -38.1 -38.4 -39.2 -35.2 -37.1 -34.8 -39.0
ALA_73 -41.9 -26.7 0.0022 -32.3 -33.3 -35.7 -32.1 -32.7 -35.8 -31.9 -34.4 -31.8 -34.4 -32.4 -27.8 -30.7 -31.0 -35.8 -28.6 -41.5 -30.7 -29.1 -31.1 -26.7 -31.7 -32.7 -41.9 -40.3
ARG_74 -42.4 -22.4 0.0033 -35.3 -28.9 -29.1 -34.9 -30.9 -22.4 -33.9 -27.1 -35.8 -30.3 -29.6 -36.6 -36.9 -36.7 -27.1 -40.3 -27.8 -35.2 -35.4 -35.0 -42.4 -33.6 -28.2 -28.1 -27.6
LYS_75 -66.0 -34.3 0.0106 -55.3 -66.0 -54.2 -55.9 -57.0 -59.8 -54.2 -62.7 -34.3 -37.8 -55.1 -52.4 -45.0 -38.7 -48.7 -49.3 -57.0 -44.8 -57.9 -63.2 -40.9 -45.0 -52.5 -54.7 -63.2
MET_76 -129.3 100.3 0.4524 35.6 -53.8 53.4 99.6 45.3 68.8 -9.2 -37.7 74.9 100.3 70.6 90.8 -31.0 -8.0 67.0 -16.5 2.1 55.5 -32.0 86.6 -129.3 -33.0 96.5 -53.6 89.1
LYS_77 -113.5 -8.9 0.1819 -104.5 -23.4 -100.0 -92.7 -97.4 -90.0 -24.4 -8.9 -103.2 -102.6 -90.1 -96.7 -44.1 -30.3 -113.5 -24.0 -31.8 -100.9 -17.8 -107.1 -54.8 -43.4 -47.7 -33.8 -97.9
ASP_78 -88.8 -6.6 0.0953 -6.6 -47.8 -8.2 -9.1 -6.8 -7.3 -40.0 -61.5 -6.9 -11.3 -14.9 -8.0 -66.3 -35.3 -8.3 -54.2 -71.7 -9.5 -43.9 -6.7 -88.8 -42.7 -63.9 -42.1 -8.3
THR_79 36.1 46.6 0.0016 46.6 37.2 45.8 44.2 45.1 44.9 37.6 41.8 44.6 41.5 46.6 45.2 38.6 40.9 46.1 38.8 44.1 43.7 39.8 44.5 36.1 38.6 40.5 39.3 46.4
ASP_80 165.8 174.4 0.0007 167.6 168.4 168.2 168.1 172.2 169.9 172.8 168.8 166.7 169.4 167.8 171.6 167.8 167.3 169.3 170.8 166.0 168.1 173.4 174.4 168.0 169.8 170.1 165.8 167.4
SER_81 -19.9 -19.3 0.0 -19.7 -19.6 -19.6 -19.6 -19.5 -19.8 -19.6 -19.7 -19.7 -19.7 -19.8 -19.7 -19.6 -19.9 -19.5 -19.5 -19.6 -19.9 -19.3 -19.4 -19.7 -19.6 -19.7 -19.6 -19.4
GLU_82 -54.7 -28.8 0.0091 -33.7 -44.7 -48.6 -44.7 -34.1 -36.9 -28.8 -54.7 -49.7 -32.1 -45.3 -47.2 -38.5 -47.3 -31.7 -30.6 -49.0 -45.1 -31.5 -36.0 -38.7 -39.2 -54.6 -49.3 -48.1
GLU_83 -27.8 -19.6 0.0006 -19.9 -19.7 -20.7 -19.9 -21.6 -19.7 -19.9 -19.7 -19.7 -22.3 -19.8 -19.8 -19.8 -19.6 -19.9 -19.8 -19.7 -20.0 -26.2 -20.0 -19.7 -19.8 -20.0 -19.6 -27.8
GLU_84 -57.6 -28.0 0.0089 -42.9 -39.9 -41.4 -40.6 -40.2 -48.8 -41.0 -29.3 -38.4 -33.6 -44.8 -39.8 -50.5 -42.6 -41.4 -32.1 -49.5 -48.9 -42.5 -28.0 -50.7 -57.6 -54.1 -28.7 -35.7
ILE_85 -48.4 -37.0 0.0013 -42.0 -44.6 -42.6 -43.4 -41.9 -37.6 -40.4 -45.9 -47.4 -48.4 -39.6 -40.0 -41.4 -42.7 -41.8 -45.8 -40.7 -41.9 -40.4 -45.7 -37.0 -40.1 -38.5 -45.8 -44.9
ARG_86 -56.0 -29.5 0.0066 -41.1 -42.7 -43.6 -40.4 -46.0 -54.8 -48.6 -43.9 -38.6 -39.9 -51.5 -54.3 -30.6 -45.4 -35.2 -43.7 -45.7 -29.5 -39.2 -47.0 -56.0 -39.6 -37.0 -46.8 -44.0
GLU_87 -28.6 -19.4 0.0009 -22.3 -20.8 -21.2 -21.4 -22.1 -22.2 -21.9 -22.8 -22.1 -23.0 -24.2 -24.4 -27.4 -21.4 -28.6 -24.5 -24.6 -28.0 -25.4 -19.6 -19.4 -26.3 -26.3 -23.0 -23.5
ALA_88 -51.2 -39.1 0.0016 -46.0 -46.6 -51.2 -47.8 -43.8 -49.3 -47.8 -42.9 -47.4 -47.2 -47.4 -46.4 -42.1 -48.2 -39.1 -40.8 -41.7 -40.4 -42.5 -49.3 -47.3 -40.6 -42.6 -44.2 -45.9
PHE_89 -33.6 -22.4 0.0016 -24.7 -24.5 -25.4 -23.2 -26.0 -24.0 -23.3 -26.5 -22.7 -23.9 -24.7 -23.5 -33.0 -25.1 -30.7 -26.2 -28.1 -33.6 -32.0 -24.5 -22.4 -28.9 -31.3 -25.7 -23.8
ARG_90 -50.6 -42.3 0.0009 -46.6 -43.5 -44.8 -44.8 -45.7 -45.5 -45.2 -42.5 -47.7 -44.8 -46.2 -49.9 -50.6 -46.7 -48.4 -44.1 -46.2 -50.5 -49.2 -45.4 -46.2 -49.6 -49.7 -42.3 -45.0
VAL_91 -26.0 -17.6 0.0012 -20.7 -19.8 -19.5 -18.7 -17.6 -19.5 -19.4 -18.1 -22.1 -19.0 -19.1 -23.7 -25.7 -19.0 -25.5 -22.1 -23.3 -26.0 -24.1 -20.2 -20.2 -25.4 -25.9 -18.8 -18.9
PHE_92 -18.1 -4.9 0.0019 -8.3 -9.9 -8.9 -7.3 -16.3 -8.8 -13.4 -9.8 -18.1 -10.3 -11.0 -15.7 -9.3 -10.9 -5.2 -5.3 -14.8 -9.1 -4.9 -12.5 -13.8 -7.4 -12.9 -8.5 -14.1
ASP_93 52.1 76.8 0.004 68.0 64.5 67.1 76.8 52.1 69.9 59.5 73.0 65.7 68.9 67.5 66.8 60.0 67.8 62.4 64.9 68.2 62.4 59.5 67.6 66.8 63.1 58.9 71.5 60.8
LYS_94 -91.5 -19.3 0.0688 -19.8 -19.6 -19.5 -19.3 -19.8 -19.6 -19.5 -19.3 -86.0 -19.5 -19.5 -85.9 -19.6 -19.6 -19.7 -19.7 -91.5 -19.4 -19.6 -19.6 -19.7 -19.7 -19.4 -19.7 -19.9
ASP_95 3.1 26.5 0.0053 6.5 8.8 8.5 9.0 4.9 7.5 9.8 11.9 23.8 8.3 8.9 26.5 11.1 6.5 3.8 5.1 23.4 6.9 5.1 7.8 7.0 3.1 8.3 8.3 7.2
GLY_96 -102.6 38.6 0.2433 29.0 37.7 34.6 28.1 -102.6 32.2 35.7 33.5 -93.2 38.6 33.9 -93.1 12.6 36.7 12.7 23.7 -88.1 17.7 15.4 31.3 32.3 18.5 22.0 35.9 35.9
ASN_97 -75.2 29.8 0.1053 -15.4 -45.3 -49.9 -49.8 -75.2 -48.9 -1.5 -43.7 29.6 -40.6 -44.0 29.5 -13.4 -38.2 -1.0 -7.1 29.8 -12.7 -13.1 -13.2 -14.8 -9.1 -24.0 -46.6 3.7
GLY_98 -9.6 27.1 0.0124 6.9 1.1 -3.5 -2.9 27.1 -3.5 -3.6 -1.9 -8.8 -0.2 1.3 -9.6 -5.5 1.3 2.6 -2.1 -9.6 19.2 20.0 -0.8 4.4 10.0 7.7 0.1 -6.5
TYR_99 131.8 170.8 0.014 142.8 146.3 143.1 142.8 137.9 145.3 150.2 144.7 165.8 148.2 143.5 166.8 131.8 147.4 133.9 140.9 170.8 134.9 135.5 142.7 144.1 140.3 135.8 146.4 148.4
ILE_100 162.6 175.8 0.0017 165.4 166.0 166.8 166.4 166.4 165.1 166.0 165.8 162.6 166.4 166.1 169.8 167.8 166.6 170.9 175.8 167.8 170.0 166.7 165.2 166.4 174.9 164.7 165.6 175.3
SER_101 139.7 145.8 0.0003 139.9 140.1 140.3 140.0 140.0 139.8 140.8 139.9 144.3 139.9 139.7 141.0 140.9 140.0 145.8 140.4 141.7 139.9 140.0 139.8 140.6 140.7 140.1 139.8 140.5
ALA_102 -38.1 -28.9 0.0008 -34.0 -34.8 -32.1 -33.6 -30.9 -34.1 -32.9 -28.9 -32.1 -35.1 -29.9 -36.8 -33.4 -32.5 -32.3 -38.1 -33.8 -35.4 -36.0 -33.4 -32.3 -37.9 -32.9 -29.9 -36.3
ALA_103 -71.7 -51.2 0.0043 -55.2 -55.1 -55.8 -56.1 -58.3 -54.8 -55.2 -61.5 -62.8 -53.9 -58.1 -71.5 -61.7 -56.4 -57.5 -66.2 -71.7 -55.4 -56.9 -55.3 -58.5 -62.6 -51.2 -57.8 -68.7
GLU_104 -35.2 -20.1 0.0029 -24.3 -33.2 -31.9 -34.8 -30.9 -30.8 -29.2 -26.3 -29.9 -32.9 -26.9 -24.5 -35.2 -29.6 -24.4 -20.4 -25.3 -33.1 -30.5 -34.5 -31.7 -20.1 -34.9 -28.0 -24.6
LEU_105 -56.3 -46.9 0.0008 -49.8 -49.1 -47.4 -47.4 -48.5 -51.4 -46.9 -50.9 -49.7 -48.1 -51.1 -50.5 -48.9 -48.2 -52.5 -54.6 -51.3 -50.6 -47.3 -47.9 -47.7 -56.3 -48.9 -50.5 -50.9
ARG_106 -41.3 -27.7 0.0016 -32.1 -32.4 -33.1 -34.6 -32.7 -34.6 -29.8 -35.2 -32.5 -35.5 -34.4 -30.8 -37.4 -29.6 -32.5 -31.0 -27.7 -38.0 -41.3 -33.2 -34.8 -31.9 -40.1 -32.3 -27.8
HIS_107 -44.2 -31.5 0.0011 -43.9 -39.2 -40.9 -38.1 -41.4 -42.5 -42.5 -43.9 -42.6 -41.0 -43.1 -39.1 -43.1 -43.3 -41.3 -31.5 -43.3 -43.3 -44.2 -38.7 -42.3 -41.4 -42.9 -42.9 -42.6
VAL_108 -40.6 -35.7 0.0002 -38.1 -39.6 -39.1 -40.6 -39.0 -40.0 -39.1 -38.8 -40.1 -39.1 -39.7 -37.7 -38.1 -37.8 -39.2 -37.4 -38.7 -35.7 -36.4 -39.7 -39.7 -37.7 -36.3 -39.4 -38.5
MET_109 -34.9 -26.9 0.0005 -30.3 -31.3 -29.5 -26.9 -31.2 -29.6 -29.6 -30.1 -30.4 -30.7 -28.4 -32.0 -28.1 -28.9 -28.8 -32.6 -29.8 -30.1 -33.4 -30.7 -28.0 -30.4 -34.9 -27.0 -30.8
THR_110 -46.4 -41.2 0.0002 -44.2 -42.9 -44.8 -46.0 -43.9 -43.2 -44.2 -44.0 -45.0 -43.4 -42.9 -43.6 -43.6 -41.2 -46.4 -44.3 -44.3 -45.0 -44.0 -41.4 -44.2 -44.0 -42.2 -41.9 -45.2
ASN_111 -62.1 -25.1 0.0133 -27.9 -32.9 -33.9 -28.6 -27.5 -29.0 -28.5 -30.2 -31.9 -27.1 -28.4 -26.8 -26.6 -62.0 -27.3 -27.3 -29.8 -26.9 -25.5 -27.3 -36.7 -25.1 -26.7 -62.1 -27.2
LEU_112 -28.5 -20.2 0.0006 -26.7 -25.3 -26.5 -27.7 -26.9 -26.9 -27.1 -27.0 -26.6 -28.0 -27.3 -27.6 -27.7 -20.2 -26.7 -26.6 -26.7 -26.8 -27.4 -28.5 -26.0 -27.9 -27.0 -20.3 -27.2
GLY_113 24.0 70.2 0.0206 30.7 33.6 35.8 32.0 24.6 25.6 29.0 31.0 31.8 28.3 31.1 24.4 30.0 70.2 33.5 24.0 30.2 29.2 29.7 29.2 49.6 27.5 30.6 70.1 29.5
GLU_114 -177.9 151.3 0.1666 151.3 143.5 143.1 141.4 142.6 142.9 142.7 144.6 142.1 148.4 141.7 142.0 142.1 -20.8 140.5 143.4 139.6 148.7 146.0 147.4 -177.9 144.9 150.2 -17.9 150.2
LYS_115 35.9 50.9 0.0019 42.9 38.2 38.0 38.7 39.9 39.7 38.8 40.2 39.0 44.0 38.4 40.4 38.2 50.9 39.3 37.6 35.9 43.1 42.1 42.6 44.8 38.1 43.6 49.4 43.9
LEU_116 128.0 145.9 0.0027 143.0 133.2 138.5 133.0 139.2 134.6 136.5 139.7 137.6 143.9 134.7 139.5 135.5 137.4 133.9 128.0 130.9 139.2 140.6 145.9 139.5 131.6 141.7 135.8 141.6
THR_117 143.8 153.9 0.0008 146.1 146.3 147.6 147.8 147.0 148.9 145.8 152.5 145.5 146.5 147.1 148.4 148.0 146.6 150.2 146.7 146.0 143.8 144.5 146.9 145.3 150.4 145.7 153.9 145.6
ASP_118 -32.2 -19.8 0.0031 -26.2 -31.6 -29.5 -20.0 -20.3 -19.8 -19.9 -32.2 -19.8 -29.5 -25.0 -32.0 -28.5 -23.6 -26.0 -30.6 -22.9 -19.8 -25.2 -20.5 -30.9 -20.0 -20.0 -22.7 -25.3
GLU_119 -54.7 -40.8 0.0016 -40.8 -48.3 -50.4 -48.3 -49.5 -50.6 -47.8 -49.8 -54.7 -42.4 -51.0 -52.1 -50.1 -50.6 -50.6 -50.8 -50.7 -45.6 -46.8 -49.9 -44.0 -52.0 -43.2 -49.6 -48.0
GLU_120 -45.5 -31.5 0.003 -42.8 -34.8 -36.9 -31.7 -32.0 -31.5 -34.8 -41.2 -34.4 -43.5 -32.2 -33.7 -34.2 -39.9 -36.9 -41.0 -34.1 -44.4 -45.5 -37.9 -43.5 -36.1 -43.3 -38.4 -42.4
VAL_121 -47.7 -35.6 0.0018 -39.1 -38.9 -41.2 -35.8 -40.5 -39.6 -47.7 -46.0 -46.5 -37.3 -40.4 -44.5 -35.6 -42.7 -43.1 -46.9 -39.6 -37.2 -37.3 -37.2 -39.4 -44.1 -38.4 -42.2 -40.5
ASP_122 -40.8 -30.2 0.0011 -31.7 -36.5 -30.2 -32.8 -39.9 -30.8 -33.2 -31.4 -33.4 -37.7 -31.1 -40.8 -33.9 -34.8 -32.7 -31.4 -34.5 -35.8 -36.6 -35.3 -34.2 -35.1 -33.9 -35.1 -32.5
GLU_123 -45.8 -36.0 0.0011 -40.8 -38.8 -43.4 -37.6 -40.2 -40.9 -41.6 -42.6 -41.3 -37.8 -41.2 -37.5 -38.2 -36.0 -42.4 -40.4 -37.4 -44.9 -39.3 -45.8 -39.9 -41.1 -45.5 -38.3 -45.4
MET_124 -30.9 -20.9 0.0007 -24.5 -26.6 -28.0 -30.9 -26.1 -30.3 -29.0 -30.1 -29.5 -28.0 -29.6 -30.4 -29.6 -27.6 -28.0 -20.9 -28.9 -27.2 -28.4 -28.4 -28.2 -29.1 -26.8 -30.3 -26.9
ILE_125 -31.6 -25.9 0.0003 -28.7 -29.3 -26.9 -25.9 -28.7 -26.7 -27.3 -26.2 -28.1 -26.8 -28.2 -26.3 -28.0 -27.9 -29.8 -31.6 -28.1 -26.1 -26.3 -29.4 -29.0 -26.5 -29.0 -26.3 -26.9
ARG_126 -58.1 -46.7 0.001 -51.5 -52.7 -52.4 -52.0 -52.2 -51.2 -52.0 -46.7 -52.4 -53.1 -50.2 -53.1 -51.2 -52.6 -55.3 -47.0 -52.9 -57.1 -53.9 -51.4 -49.2 -58.1 -51.0 -51.7 -55.2
GLU_127 -21.8 -13.7 0.0005 -18.1 -19.4 -18.9 -18.3 -19.5 -17.9 -19.3 -19.1 -19.0 -19.6 -17.0 -16.8 -19.6 -19.7 -17.8 -21.8 -19.4 -14.6 -17.7 -18.9 -20.7 -13.7 -21.0 -16.9 -17.7
ALA_128 74.5 88.5 0.0013 79.2 75.6 75.1 78.7 76.0 80.8 77.0 78.5 76.5 74.5 88.5 80.5 77.5 76.8 77.2 77.2 76.2 80.0 78.0 76.9 77.3 79.4 76.4 84.4 76.4
ASP_129 80.7 91.4 0.0012 81.2 82.2 81.3 82.0 81.4 81.0 82.1 91.4 81.4 81.5 88.9 81.7 82.6 82.5 82.7 82.0 81.7 81.5 80.7 81.9 82.0 82.5 81.7 89.9 83.0
ILE_130 0.2 130.3 0.1524 2.8 2.1 2.5 1.0 3.2 3.0 0.9 75.8 3.4 2.4 130.2 1.9 2.1 2.3 2.0 3.9 1.7 0.2 1.6 1.1 1.3 1.6 1.6 130.3 1.6
ASP_131 -159.9 -145.8 0.0016 -155.3 -154.8 -158.5 -158.6 -158.1 -155.5 -159.5 -159.3 -157.6 -157.8 -145.8 -155.9 -158.4 -155.0 -155.5 -156.1 -157.9 -156.2 -157.4 -159.9 -158.1 -156.1 -157.4 -146.9 -154.6
GLY_132 -44.4 3.1 0.0126 -26.6 -29.8 -24.2 -26.3 -31.1 -27.0 -25.6 -44.4 -26.4 -25.2 2.2 -27.6 -25.8 -30.2 -29.2 -26.9 -28.7 -27.7 -29.7 -29.4 -26.9 -27.6 -26.7 3.1 -29.7
ASP_133 -84.4 51.8 0.1345 -83.4 -83.5 -82.4 -81.9 -82.5 -82.0 -83.2 -81.3 -83.6 -83.9 51.8 -82.9 -84.0 -83.0 -83.8 -83.4 -84.4 -81.8 -83.5 -84.3 -83.2 -83.1 -82.7 51.4 -83.3
GLY_134 -42.3 172.0 0.1601 -28.4 -29.3 -34.2 -30.7 -42.3 -27.7 -26.7 -5.7 -32.9 -30.9 172.0 -31.3 -31.0 -30.4 -31.9 -35.9 -31.8 -25.6 -39.9 -28.9 -33.7 -27.8 -22.8 170.9 -29.7
GLN_135 139.3 167.5 0.0074 150.8 152.9 152.1 155.5 142.2 149.7 152.1 139.3 153.3 152.4 154.4 152.9 165.0 154.9 165.2 146.4 150.4 167.5 166.4 150.1 150.3 162.7 158.7 159.2 150.6
VAL_136 148.6 151.7 0.0001 150.0 150.9 150.9 150.0 150.3 149.3 149.0 150.3 151.6 149.6 150.6 149.6 151.7 149.6 149.0 148.6 149.6 150.0 149.5 149.8 150.7 149.8 151.1 149.9 149.9
ASN_137 82.2 177.9 0.1943 170.1 177.7 155.1 102.5 175.0 174.1 174.3 103.9 160.2 155.8 158.2 173.2 96.3 173.1 88.3 164.6 172.8 82.2 83.2 174.8 157.5 88.8 89.7 177.4 177.9
TYR_138 -32.2 -19.4 0.0023 -29.6 -26.7 -31.8 -20.8 -26.1 -29.0 -26.0 -21.2 -22.7 -24.6 -21.1 -27.3 -19.4 -28.3 -24.4 -27.8 -32.2 -19.6 -20.0 -29.4 -28.9 -24.9 -19.9 -26.7 -29.5
GLU_139 -58.4 -39.1 0.003 -39.1 -46.5 -45.1 -54.3 -42.8 -42.0 -48.4 -58.4 -48.3 -43.2 -48.0 -47.7 -44.4 -43.1 -40.9 -43.2 -39.2 -42.3 -40.5 -43.3 -46.3 -39.6 -42.6 -41.3 -43.0
GLU_140 -44.2 -35.7 0.0007 -43.8 -42.0 -38.7 -39.6 -43.5 -42.0 -40.8 -39.5 -39.7 -42.9 -40.2 -42.0 -37.6 -41.6 -35.7 -42.0 -44.2 -39.0 -41.6 -42.1 -43.2 -39.0 -38.4 -42.3 -42.6
PHE_141 -39.1 -19.8 0.0055 -22.5 -19.8 -33.6 -24.7 -21.0 -21.7 -20.1 -34.4 -20.0 -20.1 -21.2 -21.2 -24.0 -20.2 -39.1 -20.5 -24.5 -35.3 -31.9 -23.0 -21.8 -33.6 -32.6 -21.3 -20.1
VAL_142 -54.6 -36.5 0.0037 -49.5 -51.4 -49.5 -52.1 -46.4 -49.8 -48.1 -54.6 -48.5 -47.6 -49.5 -48.1 -46.8 -53.4 -38.3 -52.6 -48.7 -36.9 -39.8 -43.8 -50.1 -36.5 -41.9 -48.0 -49.6
GLN_143 -34.5 -20.1 0.002 -27.6 -22.6 -30.7 -27.8 -26.5 -27.6 -27.9 -29.1 -27.4 -23.8 -24.9 -28.5 -20.1 -30.7 -25.2 -21.6 -27.2 -20.2 -23.6 -34.5 -26.0 -23.0 -20.2 -27.2 -21.1
MET_144 -42.1 -33.5 0.0006 -40.6 -39.9 -33.5 -40.4 -41.2 -36.6 -40.2 -42.1 -41.3 -36.8 -41.3 -38.8 -36.7 -37.6 -41.5 -39.4 -40.1 -40.7 -39.7 -40.5 -37.2 -41.3 -40.5 -38.0 -38.4
MET_145 -27.2 -19.4 0.0005 -24.3 -23.1 -23.6 -25.9 -20.4 -21.7 -23.5 -22.0 -22.0 -23.2 -22.0 -23.3 -22.4 -27.2 -21.7 -24.0 -22.8 -20.2 -21.8 -20.9 -22.3 -19.4 -19.6 -22.5 -22.1
THR_146 -80.0 24.0 0.2068 -60.4 -76.3 8.3 22.0 -73.7 9.0 16.3 -73.8 -57.2 -53.4 -80.0 -64.1 -66.1 17.9 -76.9 24.0 19.7 -73.3 -71.2 -71.4 -55.6 -70.1 -64.1 -63.4 -54.9
ALA_147 8.8 118.9 0.1769 115.9 118.9 113.2 19.0 116.2 114.0 116.1 114.4 8.8 17.0 118.6 115.6 118.6 115.0 118.1 114.6 115.6 114.6 117.9 115.7 117.1 115.8 118.8 115.9 14.4
LYS_148 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
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