Proteins and small molecules whose interaction with
S100A8 is thought to be biologically relevent are included in
this table.
Target Protein
Evidence of Interaction
Effect of Interaction
arachidonic acid
biochemical evidence in Mus musculus: The heterodimer of S100A8 and S100A9 was shown to ind arachidonic acid in a calcium-dependent manner by using radioactively labelled arachidonic acid (InfoCard)
S100A9 (MRP-8)
biochemical evidence in Homo sapiens: S100A8 and S100A9 were shown to form specific heterodimers by chemical cross-linking (InfoCard)
spectroscopic evidence in Homo sapiens: Changes were observed in the circular dichroism, fluorescence emission, and nuclear magnetic resonance spectra when S100A9 was mixed with S100A8 (InfoCard)