References about Troponin C

References about Troponin C

Please note: this is not intended to be a complete listing of references.

See the home page for Troponin C for more information.

Babu, A., Su, H., Ryu, Y., Gulati, J. Determination of residue specificity in the EF-hand troponin C for Ca(2+) coordination, by genetic engineering (1992) J Biol Chem 267, 15469-15474.
No information from this reference is currently stored in the database

Biekofsky, R.R, Martin, S.R, Browne, J.P, Bayley, P.M, Feeney, J. Ca2+ coordination to backbone carbonyl oxygen atoms in calmodulin and other EF-hand proteins: 15N chemical shifts as probes for monitoring individual-site ca2+ coordination (1998) Biochemistry 37, 7617-7629.
Summary: Investigates the use of the backbone (15)N chemical shift of the residue in position 8 (canonical loops) or 10 (pseudo loops) as a probe for metal ion occupancy.
No information from this reference is currently stored in the database

Brandt, P.W, George, S.E, Scachat, F. Calmodulin is intrinsically less effective that troponin C in activating skeletal muscle contraction (1994) FEBS Lett 353, 99-102.
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Brzeska, H., Venyaminov, S., Grabarek, Z., Drabikowski, W. Comparative studies on thermostability of calmodulin, skeletal muscle troponin C and their tryptic fragments (1983) FEBS Lett 153, 169-173.
No information from this reference is currently stored in the database

Campbell, A.P, Sykes, B.D Interaction of troponin I and troponin C: use of the two-dimensional nuclear magnetic resonance transferred nuclear Overhauser effect to determine the structure of teh inhibitory troponin I peptide when bound to skeletal troponin C (1991) J Mol Biol 222, 405-421.
No information from this reference is currently stored in the database

Dalgarno, D.C, Klevit, R.E, Levine, B.A, Scott, G.MM., Williams, R.JP., Gergely, J., Grabarek, Z., Leavis, P.C, Grand, R.JA., Drabikowski, W. The nature of the trifluoperazine binding sites on calmodulin and troponin C (1984) Biochim Biophys Acta 791, 164-172.
No information from this reference is currently stored in the database

Farah, C.S, Miyamoto, C.A, Ramos, C.HI., da Silva, A.CR., Quaggio, R.B, Fujimori, K., Smilie, L.B, Reinach, F.C Structural and regulatory functions of the NH2- and COOH-terminal regions of skeletal muscle troponin I (1994) J Biol Chem 269, 5230-5240.
No information from this reference is currently stored in the database

Farah, C.S, Reinach, F.C The troponin complex and regulation of muscle contraction (1995) FASEB J 9, 755-767.
No information from this reference is currently stored in the database

Findlay, W.A, Sonnichsen, F.D, Sykes, B.D Solution structure of Tr1C fragment of skeletal muscle troponin C (1994) J Biol Chem 223, 601-606.
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Foguel, D., Suarez, M.C, Barbosa, C., Rodrigues, J.JN., Jr., Sorenso, M.M, Smillie, L.B, Silva, J.L Mimicry of the calcium-induced conformational state of troponin C by low temperature under pressure (1996) Proc Natl Acad Sci USA 93, 10642-10646.
No information from this reference is currently stored in the database

Gagne, S., Tsuda, S., Li, M., Smillie, L., Sykes, B. Structures of the troponin C regulatory domains in the apo and calcium-saturated states (1995) Nat Struct Biol 2, 784-789.
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Gagne, S.M, Li, M.X, Sykes, B.D Mechanism of direct coupling between binding and induced structural change in regulatory calcium binding proteins (1997) Biochemistry 36, 4386-4392.
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George, S., Su, Z., Fan, D., Wang, S., Johnson, J.D The fourth EF-hand of calmodulin and its helix-loop-helix components: impact on calcium binding and enzyme activation (1996) Biochemistry 35, 8307-8313.
Summary: A study of calcium binding and enzyme activation properties of of several CaM/TnC chimeras and CaM mutants. All changes are in the C terminal domain of CaM. Changes in calcium affinity and off rate, cooperativity, and enzyme activation were observed for all mutants..
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George, S.E, Su, Z., Fan, D., Means, A.R Calmodulin-cardiac troponin C chimeras (1993) J Biol Chem 268, 25213-25220.
No information from this reference is currently stored in the database

George, S.E, VanBerkum, M.FA., Ono, T., Cook, R., Hanley, R.M, Putkey, J.A, Means, A.R Chimeric calmodulin-cardiac troponin C proteins differentially activate calmodulin target enzymes (1990) J Biol Chem 265, 9228-9235.
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Grabarek, Z., Tan, R.-Y., Wang, J., Tao, T., Gergely, J. Inhibition of mutant troponin C activity by an intra-domain disulphide bind (1990) Nature 345, 132-135.
No information from this reference is currently stored in the database

Grabarek, Z., Tao, T., Gergely, J. Molecular mechanism of troponin C function (1992) J Musc Res Cell Motil 13, 383-393.
No information from this reference is currently stored in the database

Greaser, M.L, Gergely, J. Reconstitution of troponin activity from three protein components (1971) J Biol Chem 246, 4226-4233.
No information from this reference is currently stored in the database

Herzberg, O., James, M.NG. Structure of the calcium regulatory muscle protein troponin-C at 2.8 A resolution (1985) Nature 313, 653-659.
No information from this reference is currently stored in the database

Herzberg, O., Moult, J., James, M.NG. A model for the Ca(2+)-induced conformational transition of troponin C (1986) J Biol Chem 261, 2638-2644.
Summary: The original paper on what became known as the HMJ model of TnC/CaM structure and function..
No information from this reference is currently stored in the database

Houdusse, A., Love, M.L, Dominguez, R., Grabarek, Z., Cohen, C. Structures of four Ca2+-bound troponin C at 2.0 angstrom resolution: further insights into the Ca2+-switch in the calmodulin superfamily (1997) Structure 5, 1695-1711.
Summary: .
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Li, M.X, Gagne, S.M, Spyracopoulos, L., Loks, C.PA., Audette, G., Chandra, M., Solaro, R.J, Smillie, L.B, Sykes, B.D NMR studies of Ca2+ binding to the regulatory domain of cardiac and E41A skeletal muscle troponin C reveal the importance of site I to energetics of the induced structural change (1997) Biochemistry 36, 12519-12525.
No information from this reference is currently stored in the database

Li, M.X, Gagne, S.M, Tsuda, S., Kay, C.M, Smillie, L.B, Sykes, B.D Calcium binding to the regulatory N-domain of skeletal muscle troponin C occurs in a stepwise manner (1995) Biochemistry 34, 8330-8340.
No information from this reference is currently stored in the database

Lin, X., Krudy, G.A, Howarth, J., Brito, R.MM., Rosevear, P.R, Putkey, J.A Assignment and calcium dependence of methionyl (e)C and (e)H resonances in cardiac troponin C (1994) Biochemistry 33, 14434-14442.
No information from this reference is currently stored in the database

Massom, L., Lee, H., Jarrett, H.W Trifluoperazine binding to porcine brain calmodulin and skeletal muscle troponin C (1990) Biochemistry 29, 671-681.
No information from this reference is currently stored in the database

Pearlstone, J.R, McCubbin, W.D, Kay, C.M, Sykes, B.D, Smilie, L.B Spectroscopic analysis of a methionine-48 to tyrosine mutant of chicken troponin C (1992) Biochemistry 31, 9703-9708.
No information from this reference is currently stored in the database

Putkey, J.A "Troponin C" in Guidebook to the Calcium-Binding Proteins, M.R.Celio, T.Pauls, B.Schwaller, eds. (1996) Oxford University Press, Oxford. 175-178.
No information from this reference is currently stored in the database

Putkey, J.A, Sweeney, H.L, Campbell, S.T Site-directed mutation of the trigger calcium-binding sites in cardiac troponin C (1989) J Biol Chem 264, 12370-12378.
No information from this reference is currently stored in the database

Rao, S.T, Satyshur, K.A, Greaser, M.L, Sundaralingam, M. X-ray structures of Mn, Cd, and Tb metal complexes of troponin C (1996) Acta Crystall D 52, 916-922.
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Satyshur, K., Rao, S., Pyzalska, D., Drendel, W., Greaser, M., Sundraralingam, M. Refined structure of chicken skeletal muscle troponin C in the two-calcium state at 2 angstrom resolution (1988) J Biol Chem 263, 1628-1647.
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Satyshur, K.A, Pyzalska, D., Greaser, M., Rao, S.T, Sundaralingam, M. Structure of chicken skeletal muscle troponin C at 1.78 A resolution (1994) Acta Crystall D 50, 40-49.
No information from this reference is currently stored in the database

Sekharudu, Y.C, Sundaralingam, M. A structure-function relationship for the calcium affinities of regulatory proteins containing 'EF-hand' pairs (1988) Protein Eng 2, 139-146.
Summary: The authors performed QSAR analysis on calmodulin, troponin C, and parvalbumin, and used this to infer the effect of ligands and hydrophobicity of other residues on calcium affinity.
No information from this reference is currently stored in the database

Shaw, G.S, Sykes, B.D NMR solution structure of a synthetic troponin C heterodimeric domain (1996) Biochemistry 35, 7429-7438.
Summary: The reference for pdb entry 1PON.
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Sia, S.K, Li, M.X, Spyracopoulos, L., Gagne, S.M, Liu, W., Putkey, J.A, Sykes, B.D Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain (1997) J Biol Chem 272, 18216-18221.
Summary: The reference for pdb entry 3CTN.
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Slupsky, C.M, Sykes, B.D NMR solution structure of calcium-saturated skeletal muscle troponin C (1995) Biochemistry 34, 15953-15964.
Summary: The reference for pdb entry 1TNW.
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Smith, L., Greenfield, N.J, Hitchcock-DeGregori, S.E The effects of deletion of the amino-terminal helic on troponin C function and stability (1994) J Biol Chem 269, 9857-9863.
No information from this reference is currently stored in the database

Spyracopoulos, L., Li, M.X, Sia, S.K, Gagne, S.M, Chandra, M., Solaro, R.J, Sykes, B.D Calcium-induced structural transition in the regulatory domain of human cardiac troponin C (1997) Biochemistry 36, 12138-12146.
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Strynadka, N.CJ., Cherney, M., Sielecki, A.R, Li, M.X, Smillie, L.B, James, M.NG. Structural details of a calcium-induced molecular switch: X-ray crystallographic analysis of the calcium-saturated N-terminal domain of troponin C at 1.75 A resolution (1997) J Mol Biol 273, 238-255.
Summary: Presents the crystal structure of calcium-loaded troponin C N domain, and compares it to the apo TnC-N domain fromt he earlier crystal structure. Based on these structures, the authors present an interesting hypothesis about the mechanism of calcium-induced opening.
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Szczesna, D., Guzman, G., Miller, T., Zhao, J., Farokhi, K., Ellemberger, H., Potter, J.D The role of the four Ca2+ binding sites of troponin C in the regulation of skeletal muscle contraction (1996) J Biol Chem 271, 8381-8386.
No information from this reference is currently stored in the database

Vassylyev, D.G, Takeda, S., Wakatsuki, S., Maeda, K., Maeda, Y. Crystal structure if troponin C in complex with troponin I fragment at 2.3-A resolution (1998) Proc Natl Acad Sci USA 95, 4847-4852.
Summary: The first high resolution structural information about the TnC-TnI complex. There are two Ca2+ ions bound, to TnC-C. The TnI fragment also binds mostly to TnC-C..
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Zot, H.G, Potter, J.D A structural role for the Ca2+-Mg2+ sites on troponin C in the regulation of muscle contraction: preparation of troponin C depleted myofibrils (1982) J Biol Chem 257, 7678-7683.
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