Information in the EF-Hand Calcium-Binding Proteins Database from Reference 718

Protein	Species	Information	Comment	Submitted By	Validated By
calmodulin isoform 1 the main isoform, and the only isoform found in most species	Homo sapiens (human)	biochemical evidence of interaction with IQGAP1: Affinity chromatography demonstrates that IQGAP1 binds to calmodulin-Sepharose in a calcium-dependent manner. IQGAP1 co-immunoprecipitates with calmodulin from malignant human breast epithelial cells.		David B. Sacks Brigham and Women's Hospital, Department of Pathology dsacks@rics.bwh.harvard.edu	Melanie R. Nelson mnelson@scripps.edu
calmodulin isoform 1 the main isoform, and the only isoform found in most species	Homo sapiens (human)	effect of interaction with IQGAP1: Calmodulin decreases the binding of activated Cdc42 to IQGAP1		David B. Sacks Brigham and Women's Hospital, Department of Pathology dsacks@rics.bwh.harvard.edu	Melanie R. Nelson mnelson@scripps.edu