Information in the EF-Hand Calcium-Binding Proteins Database from Reference 649

Information in the EF-Hand Calcium-Binding Proteins Database from Reference 649

Protein	Species	Information	Submitted By	Validated By
calmodulin isoform 1 the main isoform, and the only isoform found in most species	Drosophila melanogaster (fruit fly)	Report of an engineered mutant with following mutations: E31Q E104Q	Melanie R. Nelson The Scripps Research Institute, Department of Molecular Biology mnelson@scripps.edu	Melanie R. Nelson mnelson@scripps.edu
calmodulin isoform 1 mutant: E31Q E104Q	Drosophila melanogaster (fruit fly)	Information about the activation of skeletal muscle myosin light chain kinase by this protein: can activate skeletal muscle myosin light chain kinase	Melanie R. Nelson The Scripps Research Institute, Department of Molecular Biology mnelson@scripps.edu	Melanie R. Nelson mnelson@scripps.edu
calmodulin isoform 1 mutant: E31Q E104Q	Drosophila melanogaster (fruit fly)	Information about the activation of skeletal muscle myosin light chain kinase by this protein: Percent activation (relative to wildtype) = 48 %	Melanie R. Nelson The Scripps Research Institute, Department of Molecular Biology mnelson@scripps.edu	Melanie R. Nelson mnelson@scripps.edu
calmodulin isoform 1 mutant: E31Q E104Q	Drosophila melanogaster (fruit fly)	Information about the activation of skeletal muscle myosin light chain kinase by this protein: K_act = 2236.8 nM	Melanie R. Nelson The Scripps Research Institute, Department of Molecular Biology mnelson@scripps.edu	Melanie R. Nelson mnelson@scripps.edu
calmodulin isoform 1 mutant: E31Q E104Q	Drosophila melanogaster (fruit fly)	biochemical evidence of interaction with skeletal muscle myosin light chain kinase: Activation was observed in vitro	Melanie R. Nelson The Scripps Research Institute, Department of Molecular Biology mnelson@scripps.edu	Melanie R. Nelson mnelson@scripps.edu
calmodulin isoform 1 the main isoform, and the only isoform found in most species	Drosophila melanogaster (fruit fly)	Report of an engineered mutant with following mutations: E31Q E67Q	Melanie R. Nelson The Scripps Research Institute, Department of Molecular Biology mnelson@scripps.edu	Melanie R. Nelson mnelson@scripps.edu
calmodulin isoform 1 mutant: E31Q E67Q	Drosophila melanogaster (fruit fly)	Information about the activation of skeletal muscle myosin light chain kinase by this protein: can activate skeletal muscle myosin light chain kinase	Melanie R. Nelson The Scripps Research Institute, Department of Molecular Biology mnelson@scripps.edu	Melanie R. Nelson mnelson@scripps.edu
calmodulin isoform 1 mutant: E31Q E67Q	Drosophila melanogaster (fruit fly)	Information about the activation of skeletal muscle myosin light chain kinase by this protein: K_act = 1311.7 nM	Melanie R. Nelson The Scripps Research Institute, Department of Molecular Biology mnelson@scripps.edu	Melanie R. Nelson mnelson@scripps.edu
calmodulin isoform 1 mutant: E31Q E67Q	Drosophila melanogaster (fruit fly)	biochemical evidence of interaction with skeletal muscle myosin light chain kinase: Activation was observed in vitro	Melanie R. Nelson The Scripps Research Institute, Department of Molecular Biology mnelson@scripps.edu	Melanie R. Nelson mnelson@scripps.edu
calmodulin isoform 1 the main isoform, and the only isoform found in most species	Drosophila melanogaster (fruit fly)	Report of an engineered mutant with following mutations: E104Q E140Q	Melanie R. Nelson The Scripps Research Institute, Department of Molecular Biology mnelson@scripps.edu	Melanie R. Nelson mnelson@scripps.edu
calmodulin isoform 1 mutant: E104Q E140Q	Drosophila melanogaster (fruit fly)	Information about the activation of skeletal muscle myosin light chain kinase by this protein: can activate skeletal muscle myosin light chain kinase	Melanie R. Nelson The Scripps Research Institute, Department of Molecular Biology mnelson@scripps.edu	Melanie R. Nelson mnelson@scripps.edu
calmodulin isoform 1 mutant: E104Q E140Q	Drosophila melanogaster (fruit fly)	Information about the activation of skeletal muscle myosin light chain kinase by this protein: Percent activation (relative to wildtype) = 8 %	Melanie R. Nelson The Scripps Research Institute, Department of Molecular Biology mnelson@scripps.edu	Melanie R. Nelson mnelson@scripps.edu
calmodulin isoform 1 mutant: E104Q E140Q	Drosophila melanogaster (fruit fly)	biochemical evidence of interaction with skeletal muscle myosin light chain kinase: Activation was observed in vitro	Melanie R. Nelson The Scripps Research Institute, Department of Molecular Biology mnelson@scripps.edu	Melanie R. Nelson mnelson@scripps.edu
calmodulin isoform 1 the main isoform, and the only isoform found in most species	Drosophila melanogaster (fruit fly)	Report of an engineered mutant with following mutations: E31Q E67Q	Melanie R. Nelson The Scripps Research Institute, Department of Molecular Biology mnelson@scripps.edu	Melanie R. Nelson mnelson@scripps.edu
calmodulin isoform 1 mutant: E31Q E67Q	Drosophila melanogaster (fruit fly)	Information about the activation of skeletal muscle myosin light chain kinase by this protein: can activate skeletal muscle myosin light chain kinase	Melanie R. Nelson The Scripps Research Institute, Department of Molecular Biology mnelson@scripps.edu	Melanie R. Nelson mnelson@scripps.edu
calmodulin isoform 1 mutant: E31Q E67Q	Drosophila melanogaster (fruit fly)	Information about the activation of skeletal muscle myosin light chain kinase by this protein: Percent activation (relative to wildtype) = 8 %	Melanie R. Nelson The Scripps Research Institute, Department of Molecular Biology mnelson@scripps.edu	Melanie R. Nelson mnelson@scripps.edu
calmodulin isoform 1 mutant: E31Q E67Q	Drosophila melanogaster (fruit fly)	biochemical evidence of interaction with skeletal muscle myosin light chain kinase: Activation was observed in vitro	Melanie R. Nelson The Scripps Research Institute, Department of Molecular Biology mnelson@scripps.edu	Melanie R. Nelson mnelson@scripps.edu