CaBP Data Library General Information

Information in the EF-Hand Calcium-Binding Proteins Database from Reference 551

Protein
Species
Information
Comment
Submitted By
Validated By
troponin C
skeletal isoform
Oryctolagus cuniculus
(rabbit)
biochemical evidence of involvement in skeletal muscle contraction:
  • Removal of troponin C results in muscle fibers that are relaxed at all concentrations of calcium. Supplying exogenous troponin C restores calcium-dependent cotnraction.

Melanie R. Nelson
The Scripps Research Institute, Department of Molecular Biology
mnelson@scripps.edu
Melanie R. Nelson
mnelson@scripps.edu
troponin C
skeletal isoform
Oryctolagus cuniculus
(rabbit)
effect of interaction with troponin I:
  • Binding of calcium-loaded troponin C to troponin I relieves the inhibition of the actomyosin ATPase by troponin I

Melanie R. Nelson
The Scripps Research Institute, Department of Molecular Biology
mnelson@scripps.edu
Melanie R. Nelson
mnelson@scripps.edu