| Protein |
Species |
Information |
Comment |
Submitted By |
Validated By |
|---|---|---|---|---|---|
| calbindin D9k |
Bos taurus (cow or bovine) |
Report of an engineered mutant with following mutations:
|
Melanie R. Nelson The Scripps Research Institute, Department of Molecular Biology mnelson@scripps.edu |
Melanie R. Nelson mnelson@scripps.edu |
|
| calbindin D9k |
Bos taurus (cow or bovine) |
Report of an engineered mutant with following mutations:
|
Melanie R. Nelson The Scripps Research Institute, Department of Molecular Biology mnelson@scripps.edu |
Melanie R. Nelson mnelson@scripps.edu |
|
| calbindin D9k mutant:
|
Bos taurus (cow or bovine) |
structure by NMR (pdb entry 1BOD) of full length protein
|
Melanie R. Nelson The Scripps Research Institute, Department of Molecular Biology mnelson@scripps.edu |
Melanie R. Nelson mnelson@scripps.edu |
|
| calbindin D9k mutant:
|
Bos taurus (cow or bovine) |
structure by NMR (pdb entry 1BOC) of full length protein
|
Melanie R. Nelson The Scripps Research Institute, Department of Molecular Biology mnelson@scripps.edu |
Melanie R. Nelson mnelson@scripps.edu |
|
| calbindin D9k mutant:
|
Bos taurus (cow or bovine) |
Proton NMR assignments indicate that this mutant adopts the canonical EF hand fold (binding with side chains, not the backbone). However, the calcium-loaded state seems to adopt the same global fold ("closed") as the wildtype protein, in which the first binding loop binds calcium with mostly its backbone atoms. | Melanie R. Nelson The Scripps Research Institute, Department of Molecular Biology mnelson@scripps.edu |
Melanie R. Nelson mnelson@scripps.edu |