References in the EF-hand Calcium-Binding Proteins Data Library

Please note: this is not intended to be a complete listing of references.

Abagyan, R.A, Totrov, M.M Contact area difference (CAD): A robust measure to evaluate accuracy of protein models (1997) J Mol Biol 268, 678-685.
No information from this reference is currently stored in the database

Adelstein, R. Calmodulin and the regulation of the actin-myosin interaction in smooth muscle and nonmuscle cells (1982) Cell 30, 349-350.
No information from this reference is currently stored in the database

Afshar, M., Caves, L.SD., Guimard, L., Hubbard, R.E, Calas, B., Grassy, G., Haiech, J. Investigating the high affinity and low sequence specificity of calmodulin binding to its targets (1994) J Mol Biol 244, 554-571.
No information from this reference is currently stored in the database

Agell, N., Aligue, R., Alemany, V., Castro, A., Jaime, M., Pujol, M.J, Rius, E., Serratosa, J., Taules, M., Bachs, O. New nuclear functions for calmodulin (1998) Cell Calcium 23, 115-121.
Summary: A brief review of propsed functions fo calmodulin in the nucleus, including regulation of cyclin dependent protein kinases and transcription by RNA polymerase III.
No information from this reference is currently stored in the database

Agrafiotis, D.K A new method for analyzing protein sequence relationships based on Sammon maps (1997) Protein Sci 6, 287-293.
Summary: Uses a technique called Sammon mapping to map sequence similarities in the protein kinase superfamily, with a focus on semonstarting the usefulness and validity of this technique of data analysis.
No information from this reference is currently stored in the database

Ahmed, F.R, Przybylska, M., Rose, D.R, Birnbaum, G.I, Pippy, M.E, MacManus, J.P Structure of oncomodulin refined at 1.85 angstrom resolution: an example of extensive molecular aggregation via Ca(2+) (1990) J Mol Biol 216, 127-140.
Summary: later refined to higher resolution.
View information in the CaBP database derived from this reference

Ahmed, F.R, Rose, D.R, Evans, S.V, Pippy, M.E, To, R. Refinement of recombinant oncomodulin at 1.30 angstrom resolution (1993) J Mol Biol 230, 1216-1224.
View information in the CaBP database derived from this reference

Akke, M., Bruschweiler, R., Palmer, A.GN., III. NMR order parameters and free energy: An analytical approach and its application to cooperative Ca2+ binding by calbindin D9k (1993) J Am Chem Soc 115, 9832-9833.
No information from this reference is currently stored in the database

Akke, M., Drakenberg, T., Chazin, W.J Three-dimensional solution structure of Ca2+-loaded porcine calbindin D9k determined by nuclear magnetic resonance spectroscopy (1992) Biochemistry 31, 1011-1020.
Summary: The reference for pdb entry 1CB1.
View information in the CaBP database derived from this reference

Akke, M., Forsen, S., Chazin, W. Solution structure of (Cd(2+)1-calbindin D9k reveals details of the stepwise structural changes along the apo -> (Ca(2+))II,1 -> (Ca(2+))I,II,2 binding pathway (1995) J Mol Biol 252, 102-121.
View information in the CaBP database derived from this reference

Akke, M., Forsen, S., Chazin, W.J Molecular basis for cooperativity in Ca2+ binding in calbindin D9k (1991) J Mol Biol 220, 173-189.
No information from this reference is currently stored in the database

Akke, M., Palmer, A.GN., III. Monitoring macromolecular motions on microsecond to millisecond time scales by R1p - R1 constant relaxation time NMR spectroscopy (1996) J Am Chem Soc 118, 911-912.
No information from this reference is currently stored in the database

Akke, M., Skelton, N.J, Kordel, J., Palmer, A.GN., III., Chazin, W.J Effects of ion binding on the backbone dynamics of calbindin D9k determined by 15N NMR relaxation (1993) Biochemistry 32, 9832-9844.
No information from this reference is currently stored in the database

Alexander, K.A, Cimler, B.M, Meier, K.E, Storm, D.R Regulation of calmodulin binding to P-57 (1987) J Biol Chem 262, 6108-6113.
No information from this reference is currently stored in the database

Alexander, K.A, Wakim, B.T, Doyle, G.S, Walsh, K.A, Storm, D.R Identification and characterization of the calmodulin-binding domain of neuromodulin, a neurospecific calmodulin-binding protein (1988) J Biol Chem 263, 7544-7549.
No information from this reference is currently stored in the database

Alexianu, M.E, Ho, B.-K., Mohamed, A.H, La Bella, V., Smith, R.G, Appel, S.H The role of calcium-binding proteins in selective motoneuron vulnerability in amyotrophic lateral sclerosis (1994) Ann Neurol 36, 846-858.
View information in the CaBP database derived from this reference

Allore, R., O'Hanlon, D., Price, R., Neilson, K., Willard, H.F, Cox, D.R, Marks, A., Dunn, R.J Gene encoding the beta subunit of S100 protein is on chromosome 21: Implications for Down syndrome (1988) Science 239, 1311-1313.
View information in the CaBP database derived from this reference

Allore, R.J, Friend, W.C, O'Hanlon, D., Neilson, K.M, Baumal, R., Dunn, R.J, Marks, A. Cloning and expression of the human S100B gene (1990) J Biol Chem 265, 15537-15543.
View information in the CaBP database derived from this reference

Ames, J.A, Porumb, T., Tanaka, T., Ikura, M., Stryer, L. Amino-terminal myristoylation induces cooperative calcium binding to recoverin (1995) J Biol Chem 270, 4526-4533.
Summary: This paper reports on calcium binding to both myristoylated and unmyristoylated recoverin. Myristoylation was found to lower the calcium affinty and induce cooperativity in calcium binding..
View information in the CaBP database derived from this reference

Ames, J.B, Ishima, R., Tanaka, T., Gordon, J.I, Stryer, L., Ikura, M. Molecular mechanics of calcium-myristoyl switches (1997) Nature 389, 198-202.
Summary: Describes the NMR structure of calcium-loaded myristoylated recoverin, in which calcium is bound to EF-2 and EF-3, and makes some basic comparisons with the apo NMR structure and the crystal strucutre in which one calcium ion is bound..
View information in the CaBP database derived from this reference

Ames, J.B, Tanaka, T., Stryer, L., Ikura, M. Portrait of a myristoyl switch protein (1996) Curr Opin Struct Biol 6, 432-438.
No information from this reference is currently stored in the database

An, J., Nakama, T., Sarai, A. 3DinSight: an integrated relational database and search tool for the structure, function and properties of biomolecules (1998) Bioinformatics 14, 188-195.
Summary: A promising relational database for integrating a variety of information about biomolecules, with a current emphasis on structural and sequence information.
No information from this reference is currently stored in the database

Andersson, M., Malmendal, A., Linse, S., Ivarsson, I., Forsen, S., Svensson, L.A Structural basis for the negative allostery between Ca2+- and Mg2+-binding to the intacellular Ca2_-receptor calbindin D9k (1997) Protein Sci 6, 1139-1147.
Summary: Presents the crystal structures of calbindin D9k with either one magneisum or one manganese ion bound to site II. These two structures adopt similar conformations, unique from the apo or Ca2+-loaded conformations of calbindin. The paper also presents Mg2+-binding constants and Ca2+ constants measured in the presence of Mg2+..
View information in the CaBP database derived from this reference

Andreasen, T.J, Keller, C.H, LaPorte, D.C, Edelman, A.M, Storm, D.R Preparation of azidocalmodulin: a photoaffinity label for calmodulin-binding proteins (1981) Proc Natl Acad Sci USA 78, 2782-2785.
No information from this reference is currently stored in the database

Anglister, J., Ren, H., Klee, C.B, Bax, A. NMR identification of calcineurin B residues affected by binding of a calcineurin A peptide (1995) FEBS Lett 375, 108-112.
No information from this reference is currently stored in the database,,,,,,,,

Archer, S.J, Ikura, M., Torchia, D.A, Bax, A. An alternative 3D NMR technique for correlating backbone 15N with sidechain H--resonances in larger proteins (1991) J Magn Reson 95, 636-641.
No information from this reference is currently stored in the database

Babu, A., Su, H., Ryu, Y., Gulati, J. Determination of residue specificity in the EF-hand troponin C for Ca(2+) coordination, by genetic engineering (1992) J Biol Chem 267, 15469-15474.
No information from this reference is currently stored in the database

Babu, Y.S, Bugg, C.E, Cook, W.J Structure of calmodulin refined at 2.2 angstrom resolution (1988) J Mol Biol 204, 191-204.
View information in the CaBP database derived from this reference

Babu, Y.S, Sack, J.S, Greenhough, T.J, Bugg, C.E, Means, A.R, Cook, W.J Three-dimensional structure of calmodulin (1985) Nature 315, 37-40.
View information in the CaBP database derived from this reference

Bachs, O., Agell, N., Carafoli, E. Calmodulin and calmodulin-binding proteins in the nucleus (1994) Cell Calcium 16, 289-296.
Summary: good review of biological function of calmodulin in the nucleus.
No information from this reference is currently stored in the database

Bagshaw, C.R, Kendrick-Jones, J. Characterization of homologous divalent metal ion binding sites of vertebrate and molluscan myosins using electro paramagnetic resonance spectroscopy (1979) J Mol Biol 130, 317-336.
No information from this reference is currently stored in the database

Baimbridge, K.G, Celio, M.R, Rogers, J.H Calcium-binding proteins in the nervous system (1992) Trends Neurosci 15, 303-308.
No information from this reference is currently stored in the database

Baldellon, C., Alattia, J.-R., Strub, M.-P., Pauls, T., Berchtold, M.W, Cave, A., Padilla, A. 15N NMR relaxation studies of calcium-loaded parvalbumin show tight dynamics compared to those of other EF-hand proteins (1998) Biochemistry 37, 9964-9975.
No information from this reference is currently stored in the database

Baldellon, C., Padilla, A., Cave, A. Kinetics of amide proton exchange in parvalbumin studied by (1)H 2-D NMR. A comparison of the calcium and magnesium loaded forms (1992) Biochimie 74, 837-844.
No information from this reference is currently stored in the database

Balmain, N. Calbindin D(9k): A vitamin D dependent, calcium-binding protein in mineralized tissues (1991) Clin Orthop 265, 265-276.
Summary: A summary of what is known about the role of calbindin in bones and teeth..
No information from this reference is currently stored in the database

Ban, C., Ramakrishnan, B., Ling, K.Y, Kung, C., Quiocho, F.A Structure of recombinant Paramecium tetraurella calmodulin at 1.68 angstrom resolution (1994) Acta Crystall D 50, 50-63.
View information in the CaBP database derived from this reference

Barbato, G., Ikura, M., Kay, L.E, Pastor, R.W, Bax, A. Backbone dynamics of calmodulin studied by (15)N relaxation using inverse deteced two-dimensional NMR spectroscopy: the central helix is flexible (1992) Biochemistry 31, 5269-5278.
No information from this reference is currently stored in the database

Barger, S.W, Van Eldik, L.J S100 beta stimulates calcium fluxes in glial and neuronal cells (1992) J Biol Chem 267, 9689-9694.
No information from this reference is currently stored in the database

Barger, S.W, Wolchok, S.R, Van Eldik, L.J Disulfide-linked S100B dimers and signal transduction (1992) Biochim Biophys Acta 1160, 105-112.
No information from this reference is currently stored in the database

Barraclough, R. "S100A4" in Guidebook to the Calcium-Binding Proteins, M.R.Celio, T.Pauls, B.Schwaller, eds. (1996) Oxford University Press, Oxford. 139-141.
View information in the CaBP database derived from this reference

Barraclough, R., Rudland, P.S The S100-related calcium-binding protein, p9Ka, and metastasis in rodent and human mammary cells (1994) Eur J Cancer 30A, 1570-1576.
Summary: Describes the use of an antibody specifc for p9Ka to look at the tissue distribution and subcellular localization of this protein..
View information in the CaBP database derived from this reference

Baudier, J., Bergeret, E., Bertacchi, N., Weintraub, H., Gagnon, J., Garin, J. Interactions of myogenic bHLH transcription factors with calcium-binding calmodulin and S100a (alpha alpha) proteins (1995) Biochemistry 34, 7834-7846.
View information in the CaBP database derived from this reference

Baudier, J., Delphin, C., Grunwald, D., Khochbin, S., Lawrence, J.J Characterization of the tumor suppressor protein p53 as a protein kinase C substrate and a S100b-binding protein (1992) Proc Natl Acad Sci USA 89, 11627-11631.
View information in the CaBP database derived from this reference

Baudier, J., Glasser, N., Gerard, D. Ions binding to S100 proteins (1986) J Biol Chem 261, 8192-8203.
No information from this reference is currently stored in the database

Baudier, J., Labourdette, G., Gerard, D. Rat brain S100b protein: purification, characterization, and ion binding properties. A comparison with bovine S100b protein (1985) J Neurochem 44, 76-84.
View information in the CaBP database derived from this reference

Baum, P., Furlong, C., Byers, B. Yeast gene required for spindle pole body duplication: homology of its product with Ca2+-binding proteins (1986) Proc Natl Acad Sci USA 83, 5512-5516.
No information from this reference is currently stored in the database

Baum, P., Yip, C., Goetsch, L., Byers, B. A yeast gene essential for regulation of spindle pole duplication (1988) Mol Cell Biol 8, 5386-5397.
No information from this reference is currently stored in the database

Bax, A., Clore, G.M, Driscoll, P.C, Gronenborn, A.M, Ikura, M., Kay, L.E Practical aspects of proton-carbon-carbon-proton three-dimensional correlation spectroscopy of 13C-labeled proteins (1990) J Magn Reson 87, 620-627.
No information from this reference is currently stored in the database

Bax, A., Clore, G.M, Gronenborn, A.M 1H-1H correlation via isotropic mixing of 13C magnetization, a new three-dimensional approach for assigning 1H and 13C spectra of 13C-enriched proteins (1990) J Magn Reson 88, 425-431.
No information from this reference is currently stored in the database

Bax, A., Grzesiek, S. Methodological advances in protein NMR (1993) Acc Chem Res 26, 131-138.
No information from this reference is currently stored in the database

Bax, A., Max, D., Zax, D. Long-range 13C-13C J. couplings in a 20-kDa protein-peptide complex (1992) J Am Chem Soc 114, 6923-6925.
No information from this reference is currently stored in the database

Baxevanis, A.D, Landsman, D. . Histone and histone fold sequences and structures: a database (1997) Nucleic Acids Res 25, 272-273.
No information from this reference is currently stored in the database

Bayley, P.M, Findlay, W.A, Martin, S.R Target recognition by calmodulin: Dissecting the kinetics and affinity of interaction using short peptide sequences (1996) Protein Sci 5, 1215-1228.
No information from this reference is currently stored in the database

Bazzi, M.D, Nelsestuen, G.L Protein kinase C and annexins: unusual calcium response elements in the cell (1993) Cell Signal 5, 357-365.
No information from this reference is currently stored in the database

Becker, T., Gerke, V., Kube, E., Weber, K. S100P, a novel Ca2+-binding protein from human placenta: cDNA cloning, recombinant protein expression and Ca2+ binding properties (1992) Eur J Biochem 207, 541-547.
View information in the CaBP database derived from this reference

Beckingham, K. Use of site-directed mutations in the individual Ca2+-binding sites of calmodulin to examine Ca2+-induced conformational changes (1991) J Biol Chem 266, 6027-6030.
No information from this reference is currently stored in the database

Belhadri, A. Presence of centrin in the human parasite Giardia: A further indication of its ubiquity in eukaryotes (1995) Biochem Biophys Res Comm 214, 597-601.
No information from this reference is currently stored in the database

Bentrop, D., Bertini, I., Cremonimi, M.A, Forsen, S., Luchinat, C., Malmendal, A. Solution structure of the paramagnetic complex of the N-terminal domain of calmodulin with two Ce3+ ions by (1)H NMR (1997) Biochemistry 36, 11605-11618.
View information in the CaBP database derived from this reference

Berchtold, M.W Evolution of EF-hand calcium modulated proteins. V. The genes encoding EF-hand proteins are not clustered in mammalian genomes (1993) J Mol Evol 36, 489-496.
No information from this reference is currently stored in the database

Bhardwaj, R.S, Zotz, C. ., Zwaldo-Klarwasser, G. ., Roth, J. ., Goebeler, M. ., Mahnke, K. ., Falk, M. ., Meinardus-Hager, G., Sorg, C. The calcium-binding proteins MRP8 and MRP14 form a membrane-associated heterodimer in a subset of monocytes/macrophages present in acute but absent in chronic inflammatory lesions (1992) Eur J Immunol 22, 1891-1897.
No information from this reference is currently stored in the database

Biamonti, C., Rios, C.B, Lyons, B.A, Montelione, G.T Multi-dimensional NMR experiments & analysis techniques for determining homo- and heteronuclear scalar coupling constants in proteins and nucleic acids (1994) Adv Biophys Chem 4, 51-120.
No information from this reference is currently stored in the database

Biekofsky, R.R, Martin, S.R, Browne, J.P, Bayley, P.M, Feeney, J. Ca2+ coordination to backbone carbonyl oxygen atoms in calmodulin and other EF-hand proteins: 15N chemical shifts as probes for monitoring individual-site ca2+ coordination (1998) Biochemistry 37, 7617-7629.
Summary: Investigates the use of the backbone (15)N chemical shift of the residue in position 8 (canonical loops) or 10 (pseudo loops) as a probe for metal ion occupancy.
No information from this reference is currently stored in the database

Billeter, M., Braun, W., Wuthrich, K. Sequential resonance assignments in protein 1H nuclear magnetic resonance spectra - computation of sterically allowed proton-proton distances and statistical analysis of proton-proton distances in single crystal protein conformations (1982) J Mol Biol 155, 321-346.
No information from this reference is currently stored in the database

Blanchard, H., Grochulski, P., Li, Y., Arthur, S.C, Davies, P.L, Elce, J.S, Cygler, M. Structure of a calpain Ca2+-binding domain reveals a novel EF-hand and Ca2+-induced conformational changes (1997) Nat Struct Biol 4, 532-538.
Summary: The paper for PDB entries 1AJ5 and 1DV1. It presents the structures of apo and calcium-loaded domain VI of calpain, and a preliminary analysis of the calcium-induced conformational changes, whicha re unlike any of the previously described conformational responses to calcium-binding..
View information in the CaBP database derived from this reference

Blanchard, H., Li, Y., Cygler, M., Kay, C.M, Arthur, J.SC., Davies, P.L, Elce, J.S Ca2+-binding domain VI of rat calpain is a homodimer in solution: hydrodynamic, crystallization and preliminary X-ray diffraction studies (1996) Protein Sci 5, 533-537.
Summary: The initial report of crystallization of rat calpain domain VI. The paper includes studies that show this domain to form homodimers in solution.
No information from this reference is currently stored in the database

Blancuzzi, Y., Padilla, A., Parello, J., Cave, A. Symmetrical rearrangement of the cation-binding sites of parvalbumin upon Ca(2+)/Mg(2+) exchange. A study by (1)H 2D NMR (1993) Biochemistry 32, 1302-1309.
No information from this reference is currently stored in the database

Blum, J.K, Berchtold, M.W Calmodulin-like effect of oncomodulin on cell prolifration (1994) J Cell Physiol 160, 455-462.
No information from this reference is currently stored in the database

Blumenthal, D.K, Krebs, E.G Preparation and properties of the calmodulin-binding domain of skeletal muscle myosin light chain knase (1987) Methods Enzymol 139, 115-126.
No information from this reference is currently stored in the database

Blumenthal, D.K, Takio, K. ., Edelman, A.M, Charbonneau, H. ., Titani, K. ., Walsh, K.A, Krebs, E.G Identification of the calmodulin-binding domain of skeletal muscle myosin light chain kinase (1985) Proc Natl Acad Sci USA 82, 3187-3191.
No information from this reference is currently stored in the database

Blundell, T.L, Sibanda, B.L, Sternberg, M.JE., Thornton, J.M Knowledge-based prediction of protein strucutres and the design of novel molecules (1987) Nature 326, 347-352.
No information from this reference is currently stored in the database

Bootman, M.D, Berridge, M.J The elemental principles of calcium signaling (1995) Cell 83, 675-678.
Summary: This minireview describes the fundamental units of a calcium signal in various systems and postulates on the roles of the complex types of calcium signals in biology.
No information from this reference is currently stored in the database

Borgias, B.A, James, T.L COMATOSE, a method for constrained refinement of macromolecular structure based on two-dimensional nuclear overhauser effect spectra (1988) J Magn Reson 79, 493-512.
No information from this reference is currently stored in the database

Borgias, B.A, James, T.L MARDIGRAS: A procedure for matrix analysis of relaxation for discerning geometry of an aqueous structure (1990) J Magn Reson 87, 475-487.
No information from this reference is currently stored in the database

Borgias, B.A, James, T.L Two-dimensional nuclear Overhauser effect: complete relaxation matrix analysis (1989) Methods Enzymol 176, 169-183.
No information from this reference is currently stored in the database

Bostrom, S.-L., Ljung, B., Mardh, S., Forsen, S., Thulin, E. Interaction of the antihypertensive drug felodipine with calmodulin (1981) Nature 292, 777-778.
No information from this reference is currently stored in the database

Boucher, W., Laue, E.D, Campbell-Burk, S., Domaille, P.J Four-dimensional heteronuclear triple-resonance NMR methods for the assignment of backbone nuclei in proteins (1992) J Am Chem Soc 114, 2262-2264.
No information from this reference is currently stored in the database

Bower, M.J, Cohen, F.E, Dunbrack, R.LN., Jr. Prediction of proteins side-chain rotamers from a backbone-dependent rotamer library: a new homology modeling tool (1997) J Mol Biol 267, 1268-1282.
No information from this reference is currently stored in the database

Brandt, P.W, George, S.E, Scachat, F. Calmodulin is intrinsically less effective that troponin C in activating skeletal muscle contraction (1994) FEBS Lett 353, 99-102.
View information in the CaBP database derived from this reference

Brodersen, D.E, Etzerodt, M., Celis, J.E, Thorgersen, H.C, Nyborg, J., Kjeldgaard, M. EF-hands at atomic resolution: the structure of human psoriasin (S100A7) solved by MAD phasing (1998) Structure 6, 477-489.
Summary: This paper presents the crystal structure of the S100A7 homodimer with two lanthanide ins bound and compares it to other structures of S100 proteins.
View information in the CaBP database derived from this reference

Brodersen, D.E, Nyborg, J. ., Kjeldgaard, M. . Zinc-binding site of an S100 protein revealed. Two crystal structures of Ca2+-bound human psoriasin (S100A7) in the Zn2+-loaded and Zn2+-free states (1999) Biochemistry 38, 1695-1704.
View information in the CaBP database derived from this reference

Brodin, P., Drakenberg, T., Thulin, E., Forsen, S., Grundstrom, T. Selective proton labelling of amino acids in deuterated bovine calbindin D9k. A way to simplify (1)H-NMR spectra (1989) Protein Eng 2, 353-358.
No information from this reference is currently stored in the database

Brodin, P., Grundstrom, T., Hofmann, T., Drakenberg, T., Thulin, E., Forsen, S. Expression of bovine intenstinal calcium binding protein from a synthetic gene in Escherichia coli and characterization of the product (1986) Biochemistry 25, 5371-5377.
No information from this reference is currently stored in the database

Brodin, P., Johansson, C., Forsen, S., Drakenberg, T., Grundstrom, T. Functional properties of calbindin D9k mutants with exchanged Ca(2+) binding sites (1990) J Biol Chem 265, 11125-11130.
Summary: Three mutants were made: one with two site I binding loops (mutant A), one with two site II binding loops (mutant B), and one with the site I and site II loops exchanged (mutant C). All three mutants bind calcium-- mutant B has a decrease in affinity (with respect to wildtype) of about one order of magnitude, while mutants A and C have a decrease in affinity of about two orders of magnitude. Cooperativity of binding is lost in all three mutants..
No information from this reference is currently stored in the database

Bronner, F., Pansu, D., Stein, W.F An analysis of intestinal calcium transport across the rat intestine (1986) Am J Physiol 150G, 561-569.
View information in the CaBP database derived from this reference

Brooks, B.R, Bruccoleri, R.E, Olafson, B.D, States, D.J, Swaminathan, S. ., Karplus, M. . CHARMM: A program for macromolecular energy, minimization, and dynamics calculations (1983) J Comput Chem 4, 187-217.
No information from this reference is currently stored in the database

Brooks, C.L. Karplus, M. . Pettitt, B.M. eds. Proteins:A Theoretical Perspective of Synamics, Structure, and Thermodynamics (1988) John Wiley & Sons, New York.
No information from this reference is currently stored in the database

Brun, J.G, Jonsson, R. ., Haga, H.J Measurement of plasma calprotectin as an indicator of arthritis and disease activity in patients with inflammatory rheumatic diseases (1994) J Rheumatol 21, 733-738.
No information from this reference is currently stored in the database

Bruns, M.E, Kleeman, E., Bruns, D.E Vitamin D-dependent calcium-binding protein of mouse yolk sac (1986) J Biol Chem 261, 7485-7490.
No information from this reference is currently stored in the database

Bruns, M.E, Overpeck, J.G, Smith, G.C, Hirsch, G.N, Mills, S.E Vitamin D-dependent calcium binding protein in rat uterus: differential effects of estrogen, tamoxifen, progesterone and pregnancy on accumulation and cellular localization (1988) Endocrinology 122, 2371-2378.
Summary: A study of the localization of calbindin D9k in uterine tissues of pregnant rats and hormone-treated non-pregnant rats. Estrogen only partially mimcs the effects of pregnancy on calbindin distribution.
View information in the CaBP database derived from this reference

Bryant, R.G The dynamics of water-protein interactions (1996) Annu Rev Biophys Biomol Struct 25, 29-53.
No information from this reference is currently stored in the database

Brzeska, H., Venyaminov, S., Grabarek, Z., Drabikowski, W. Comparative studies on thermostability of calmodulin, skeletal muscle troponin C and their tryptic fragments (1983) FEBS Lett 153, 169-173.
No information from this reference is currently stored in the database

Bullock, S., Hayward, C., Manson, J., Brock, D.JH., Raeburn, J.A Quantitative immunoassays for diagnosis and carrier detection in cystic fibrosis (1982) Clin Genet 21, 336-341.
View information in the CaBP database derived from this reference

Calabretta, B., Kaczmarek, L., Mars, W., Ochoa, D., Gibson, C., Hirschhorn, R., Baserga, R. Cell-cycle-specific genes differentially expressed in human leukemias (1985) Proc Natl Acad Sci USA 82, 4463-4467.
View information in the CaBP database derived from this reference

Calbretta, B., Venurelli, D., Kaczmarek, L., Narni, F., Talpaz, M., Anderson, B., Beran, M., Baserga, R. Altered expression of G1-specific genes in human malignant myeloid cell (1986) Proc Natl Acad Sci USA 83, 1495-1498.
No information from this reference is currently stored in the database

Campbell, A.P, Sykes, B.D Interaction of troponin I and troponin C: use of the two-dimensional nuclear magnetic resonance transferred nuclear Overhauser effect to determine the structure of teh inhibitory troponin I peptide when bound to skeletal troponin C (1991) J Mol Biol 222, 405-421.
No information from this reference is currently stored in the database

Carlstrom, G., Chazin, W.J Two-dimensional (1)H nuclear magnetic resonance studies of the half-saturated (Ca(2+))1 state of calbindin D9k: further implications for the molecular basis of cooperative Ca(2+) binding (1993) J Mol Biol 231, 415-430.
No information from this reference is currently stored in the database

Cave, A., Saint-Yves, A., Parello, J., Sward, M., Thulin, E., Lindman, B. NMR studies on parvalbumin phylogeny and ionic interactions (1982) Mol Cell Biochem 44, 161-172.
Summary: One of the original papers describing the spectroscopic identification of the secondary metal ion binding site found in some parvalbumins..
No information from this reference is currently stored in the database

Celio, M.R. Pauls, T. Schwaller, B. eds. Guidebook to the Calcium-Binding Proteins (1996) Oxford University Press, Oxford.
No information from this reference is currently stored in the database

Channon, J.Y, Leslie, C.C A calcium-dependent mechanism for associating a soluble arachidonoyl-hydrolyzing phospholipase A2 with membrane in the macrophage cell line RAW 264.7 (1990) J Biol Chem 265, 5409-5413.
No information from this reference is currently stored in the database

Chapman, E.R, Alexander, K., Vorherr, T., Carofoli, E., Storm, D.R Fluorescence energy transfer analysis of calmodulin-peptide complexes (1992) Biochemistry 31, 12819-12825.
No information from this reference is currently stored in the database

Charbonneau, H., Kuamr, S., Novack, J.P, Blumenthal, D.K, Griffin, P.R, Shabanowitz, J., Hunt, D.F, Beavo, J.A, Walsh, K.A Evidence for domain organization within the 61-kDa calmodulin-dependent cyclic nucleotide phosphodiesterase from bovine brain (1991) Biochemistry 30, 7931-7940.
View information in the CaBP database derived from this reference

Chard, P.S, Bleakman, D., Christakos, S., Fullmer, C.S, Miller, R.J Calcium buffering properties of calbindin D28k and parvalbumin in rat sensory neurones (1993) J Physiol 472, 341-357.
No information from this reference is currently stored in the database

Chattopadhyaya, R., Meador, W., Means, A., Quiocho, F. Calmodulin structure refined at 1.7 angstrom resolution (1992) J Mol Biol 228, 1177-1192.
View information in the CaBP database derived from this reference

Chazin, W.J New nuclear magnetic resonance structures and structural methodology (1991) Curr Opin Biotech 2, 520-525.
No information from this reference is currently stored in the database

Chazin, W.J Releasing the calcium trigger (1995) Nat Struct Biol 2, 707-710.
Summary: News and views article commenting on the structures of apo calmodulin and troponin C published in the same issue..
No information from this reference is currently stored in the database

Chazin, W.J, Kordel, J., Thulin, E., Hoffmann, T., Drakenberg, T., Forsen, S. Identification of an isoaspartyl linkage formed upon deamidation of bovine calbindin D9k and structural characterization by 2D 1H NMR (1989) Biochemistry 28, 8646-8653.
No information from this reference is currently stored in the database

Chazin, W.J, Rance, M., Wright, P.E Complete assignment of the 1H NMR magnetic resonance spectrum of french bean plastocyanin. Application of an integrated approach to spin system identification in proteins (1988) J Mol Biol 202, 603-622.
No information from this reference is currently stored in the database

Chen, C.-K., Hurley, J.B "Recoverin" in Guidebook to the Calcium-Binding Proteins, M.R.Celio, T.Pauls, B.Schwaller, eds. (1996) Oxford University Press, Oxford. 119-120.
Summary: A brief chapter summarizing the basic characteristics and properties of recoverin.
No information from this reference is currently stored in the database

Chen, C.-K., Inglese, J., Lefkowitz, R.J, Hurley, J.B Ca2+-dependent interaction of recoverin and rhodopsin kinase (1995) J Biol Chem 270, 18060-18066.
View information in the CaBP database derived from this reference

Cheney, R.E, Mooseker, M.S Unconventional myosins (1992) Curr Opin Cell Biol 4, 27-35.
Summary: Among other things, this review describes the myosins that use calmodulin for their light chains..
No information from this reference is currently stored in the database

Chin, D., Means, A.R Methionine to glutamine substitutions in the C-terminal domain of calmodulin impair the activation of three protein kinases (1996) J Biol Chem 271, 30465-30471.
Summary: Describes several single met to gln mutations in CaM and the effect of these mutations on CaMıs ability to activate CaMKIIa, smMLCK, and CaMKIV. All mutants were impaired in their ability to activate at least one of these targets..
View information in the CaBP database derived from this reference

Chothia, C., Gerstein, M. How far can sequences diverge (1997) Nature 385, 579-580.
Summary: A brief review of two recent protein engineering studies and a discussion of their implications for the amount of evolutionary divergence proteins can tolerate in their sequences.
No information from this reference is currently stored in the database

Chothis, C., Lesk, A.M The relation between the divergence of sequence and structure in proteins (1986) EMBO J 5, 823-826.
No information from this reference is currently stored in the database

Christakos, S., Gabrielides, C., Rhoten, W.B Vitamin D-dependent calcium binding proteins: chemistry, distribution, functional considerations, and molecular biology (1989) Endoc Rev 10, 3-26.
Summary: A very useful summary of information about the biology and function of calbindin D28k and calbindin D9k..
View information in the CaBP database derived from this reference

Clapham, D.E Calcium Signaling (1995) Cell 80, 259-268.
Summary: A review of the pathways and mechanisms of signal transduction involving calcium, including a section on calcium waves..
No information from this reference is currently stored in the database

Clapham, D.E, Sneyd, J. Intracellular calcium waves (1995) Adv Second Messenger Phosphoprotein Res 30, 1-24.
No information from this reference is currently stored in the database

Clementi, E., Meldolesi, J. The cross-talk between nitric ixude and Ca2+: a story with a complex past and a promising future (1997) Trends Pharmacol Sci 18, 266-269.
Summary: A brief review of the current knowledge about interaction of the Ca2+ and NO-cGMP signaling systems.
No information from this reference is currently stored in the database

Clipstone, N.A, Crabtree, G.R Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation (1992) Nature 357, 695-697.
No information from this reference is currently stored in the database

Clore, G.M, Bax, A., Driscoli, P.C, Wingfield, P.T, Gronenborn, A.M Assignment of the side-chain 1H and 13C resonances of interleukin-1 using double- and triple-resonance heteronuclear three-dimensional NMR spectroscopy (1990) Biochemistry 29, 8172-8184.
No information from this reference is currently stored in the database

Clore, G.M, Bax, A., Wingfield, P.T, Gronenborn, A.M Identification and localization of bound internal water in the solution structure of inter-leukin 1 by heteronuclear three-dimensional 1H rotating-frame Overhauser 15N- 1H multiple quantum coherence NMR spectroscopy (1990) Biochemistry 29, 5671-5676.
No information from this reference is currently stored in the database

Clore, G.M, Brunger, A.T, Karplus, M., Gronenborn, A.M Application of molecular dynamics with interproton distance restraints to three-dimensional protein structure determination. A model study of crambin (1986) J Mol Biol 191, 523-551.
No information from this reference is currently stored in the database

Clore, G.M, Gronenborn, A.M Structures of larger proteins in solution: three- and four-dimensional heteronuclear NMR spectroscopy (1991) Science 252, 1390-1399.
No information from this reference is currently stored in the database

Clore, G.M, Gronenborn, A.M Two-, three- and four-dimensional NMR methods for obtaining larger and more precise three-dimensional structures of proteins in solution (1991) Annu Rev Biophys Biophys Chem 20, 29-63.
No information from this reference is currently stored in the database

Coe, F.L, Nakagawa, Y., Asplin, J., Parks, J.H Role of nephrocalcin in inhibition of calcium oxalate crystallization and nephrolithiasis (1994) Miner Electrolyte Metab 20, 378-384.
No information from this reference is currently stored in the database

Colbran, R.J, Schworer, C.M, Hashimoto, Y., Fong, Y.-L., Rich, D.P, Smith, M.K, Soderling, T.R Calcium/calmodulin-dependent protein kinase II (1989) Biochem J 258, 313-325.
No information from this reference is currently stored in the database

Colbran, R.J, Soderling, T.R Calcium/calmodulin dependent protein kinase II (1990) Curr Topics Cell Reg 31, 181-221.
No information from this reference is currently stored in the database

Collins, J.H, Borysenko, C.W The 110,000-dalton actin- and calmodulin-binding protein from intestinal brush border is a myosin-like ATPase (1984) J Biol Chem 259, 14128-14135.
No information from this reference is currently stored in the database

Collins, K., Sellers, J.R, Matsudaira, P. Calmodulin dissociation regulates brush border myosin I (110 kD-calmodulin) mechanochemical activity in vitro (1990) J Cell Biol 110, 1137-1147.
View information in the CaBP database derived from this reference

Cook, W.J, Jeffrey, L.C, Cox, J.A, Vijay-Kumar, S. Structure of a sarcoplasmic calcium-binding protein from amphioxus refined at 2.4 A resolution (1993) J Mol Biol 229, 461-471.
View information in the CaBP database derived from this reference

Cook, W.J, Walter, L.J, Walter, M.R Drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex (1994) Biochemistry 33, 15259-15256.
View information in the CaBP database derived from this reference

Cormier, M.J, Charbonneau, H., Jarrett, H.W Plant and fungal calmodulin: Ca2+-dependent regulation of plant NAD kinase (1981) Cell Calcium 2, 313-331.
View information in the CaBP database derived from this reference

Cotton, F.A, Hazen, E.E, Legg, M.J Staphyloccocal nuclease: proposed mechanism of action based on structure of enzyme-thymidine 3ı,5ı-bisphosphate-calcium ion complex at 1.5-angstrom resolution (1979) Proc Natl Acad Sci USA 76, 2551-2555.
No information from this reference is currently stored in the database

Cox, J.A, Milos, M., MacManus, J.P Calcium- and magnesium-binding properties of oncomodulin (1990) J Biol Chem 265, 6633-6637.
View information in the CaBP database derived from this reference

Cox, J.A, Stein, E.A Characterization of a new sarcoplasmic calcium-binding protein with magnesium-induced cooperativity in the binding of calcium (1981) Biochemistry 20, 5430-5436.
Summary: The first report of the basic characteristics of sarcoplasmic calcium-binding protein from Nereis divisicolor, inclusing its calcium and magnesium binding properties.
View information in the CaBP database derived from this reference

Craig, T.A, Watterson, D.M, Prendergast, F.G, Haiech, J., Roberts, D.M Site-specific mutagenesis of the a-helices of calmodulin (1987) J Biol Chem 262, 3278-3284.
No information from this reference is currently stored in the database

Craven, C.J, Whitehead, B., Jones, S.KA., Thulin, E., Blackburn, G.M, Waltho, J.P Complexes formed between calmodulin and the antagonists J-8 and TFP in solution (1996) Biochemistry 35, 10287-10299.
No information from this reference is currently stored in the database

Crawford, C., Brown, N.R, Willis, A.C Studies of the active site of m-calpain and the interaction with calpastatin (1993) Biochem J 296, 135-142.
No information from this reference is currently stored in the database

Crivici, A., Ikura, M. Molecular and structural basis of target recognition by calmodulin (1995) Annu Rev Biophys Biomol Struct 24, 85-116.
View information in the CaBP database derived from this reference

Croall, D.E, Demartino, G.N Calcium-activated neutral protease (calpain) system: structure, function, and regulation (1991) Physiol Rev 71, 813-847.
Summary: An extensive and careful review..
View information in the CaBP database derived from this reference

da Silva, A.CR., Reinach, F.C Calcium binding induces conformational changes in muscle regulatory proteins (1991) Trends Biochem Sci 16, 53-57.
No information from this reference is currently stored in the database

Dalgarno, D.C, Klevit, R.E, Levine, B.A, Scott, G.MM., Williams, R.JP., Gergely, J., Grabarek, Z., Leavis, P.C, Grand, R.JA., Drabikowski, W. The nature of the trifluoperazine binding sites on calmodulin and troponin C (1984) Biochim Biophys Acta 791, 164-172.
No information from this reference is currently stored in the database

Dasgupta, M., Honeycutt, T., Blumenthal, D.K The gamma-subunit of skeletal muscle phosphorylase kinase contains two noncontiguous domains that act in concert to bind calmodulin (1989) J Biol Chem 264, 17156-17163.
View information in the CaBP database derived from this reference

Davies, B.R, Davies, M.PA., Gibbs, F.EM., Barraclough, R., Rudland, P.S Induction of the metastatic phenotype by transfection of a benign rat memmary epithelial cell line with the gene for p9Ka, a rat calcium-binding protein, but not with the oncogene EJ-ras-1 (1993) Oncogene 8, 999-1008.
No information from this reference is currently stored in the database

de Beer, T., Carter, R.E, Lobel-Rice, K.E, Sorkin, A., Overduin, M. Structure and Asn-Pro-Phe binding pocket of the Eps15 homology domain (1998) Science 281, 1357-1360.
No information from this reference is currently stored in the database

Declercq, J.-P., Tinant, B., Parello, J. X-ray structure of a new crystal form of pike 4.10 beta parvalbumin (1996) Acta Crystall D 52, 165-169.
Summary: The reference for pdb entry 1PVB.
View information in the CaBP database derived from this reference

Declercq, J.-P., Tinant, B., Parello, J., Etienne, G. Crystal structure determination and refinement of pike 4.10 parvalbumin (minor component from Esox lucius) (1988) J Mol Biol 202, 349-353.
No information from this reference is currently stored in the database

Declercq, J.-P., Tinant, B., Parello, J., Rambaud, J. Ionic interactions with parvalbumins: crystal structure determination of pike 4.10 parvalbumin in four different ionic environments (1991) J Mol Biol 220, 1017-1039.
View information in the CaBP database derived from this reference

Delabie, J. ., de Wolf-Peeters, C. ., van den Oord, J.J, Desmet, V.J Differential expression of the calcium-binding proteins MRP8 and MRP14 in granulomatous conditions: an immunohistochemical study (1990) Clin Exp Immunol 81, 123-126.
No information from this reference is currently stored in the database

Dell'Angelica, E.C, Schleicher, C.H, Santome, J.A Primary structure and binding properties of calgranulin C, a novel S100-like calcium-binding protein from pig granulocytes (1994) J Biol Chem 269, 28929-28936.
View information in the CaBP database derived from this reference

Delorme, A.C, Danan, J.L, Acker, M.G, Ripoche, M.A, Mathieu, H. In rat uterus 17 beta-estradiol stimulates a calcium-binding protein similar to the duodenal vitamin D-dependent calcium-binding protein (1983) Endocrinology 113, 1340-1347.
No information from this reference is currently stored in the database

Denisov, V.P, Halle, B. Direct observation of calcium-coordinated water in calbindin D9k by nuclear magnetic relaxation dispersion (1995) J Am Chem Soc 117, 8456-8465.
No information from this reference is currently stored in the database

Dennis, E.A Diversity of group types, regulation, and function of phospholipase A2 (1994) J Biol Chem 269, 13057-13060.
Summary: A concise and useful minireview.
No information from this reference is currently stored in the database

Dodson, E.J, Davies, G.J, Lamzin, V.S, Murshudov, G.N, WIlson, K.S Validation tools: can they indicate the information content of macromolecular crystal structures? (1998) Structure 6, 685-690.
No information from this reference is currently stored in the database

Doerks, T., Bairoch, A., Bork, P. Protein annotation: detective work for function prediction (1998) Trends Genet 14, 248-250.
No information from this reference is currently stored in the database

Donato, R. . Perspectives in S-100 protein biology (1991) Cell Calcium 12, 713-726.
No information from this reference is currently stored in the database

Donato, R. Calcium-independent, pH-regulated effects of S-100 proteins on assembly-disassembly of brain microtubule protein in vitro (1988) J Biol Chem 263, 106-110.
View information in the CaBP database derived from this reference

Donato, R., Isobe, T., Okuyama, T. S-100 proteins and microtubules: analysis of the effects of rat brain S-100 (S-100b) and ox brain S100a0, S-100a and S-100b on microtubule assembly-disassembly (1985) FEBS Lett 186, 65-69.
View information in the CaBP database derived from this reference

Dorin, J.R, Emslie, E., van Heyningen, V. Related calcium-binding proteins map to the same subregion of chromosome 1q and to an extended region of synteny on mouse chromosome 3 (1990) Genomics 8, 420-426.
View information in the CaBP database derived from this reference

Drakenberg, T., Sward, M., Cave, A., Parello, J. Metal-ion binding to parvalbumin (1985) Biochem J 227, 711-717.
No information from this reference is currently stored in the database

Driscoll, P.C, Clore, G.M, Dominique, M., Wingfield, P.T, Gronenborn, A. Complete resonance assignment for the polypeptide backbone of Interleukin 1 using three-dimensional NMR spectroscopy (1990) Biochemistry 29, 3542-3556.
No information from this reference is currently stored in the database

Drohat, A.C, Amburgey, J.C, Abildgaard, F., Starich, M.R, Baldisseri, D., Weber, D.J Solution structure of rat apo-S100B(bb) as determined by NMR spectroscopy (1996) Biochemistry 35, 11577-1588.
View information in the CaBP database derived from this reference

Drohat, A.C, Baldisseri, D.M, Rustandi, R.R, Weber, D.J Solution structure of calcium-bound rat S100B(bb) as determined by nuclear magnetic resonance spectroscopy (1998) Biochemistry 37, 2729-2740.
Summary: The paper for PDB entry 1QLK..
View information in the CaBP database derived from this reference

Duncan, A.MV., Higgins, J., Dunn, R.J, Allore, R., Marks, A. Refined sublocalization of the human gene encoding the b subunit of S100 protein (S100b) and confirmation of a subtle t(9:21) translocation using in situ hybridization (1989) Cytogenet Cell Genet 50, 234-235.
View information in the CaBP database derived from this reference

Durussel, I., Luan-Rilliet, Y., Petrova, T., Takagi, T., Cox, J.A Cation binding and conformation of tryptic fragments of Nereis sarcoplasmic calcium-binding protein: Calcium-induced homo- and heterodimerization (1993) Biochemistry 32, 2394-2400.
No information from this reference is currently stored in the database

Durussel, I., Pauls, T.L, Cox, J.A, Berchtold, M.W Chimeras of parvalbumin and oncomodulin involving exchange of the complete CD site show that the Ca2+/Mg2+ specificity is an intrinsic property of the site (1996) Eur J Biochem 242, 256-263.
No information from this reference is currently stored in the database

Eberhard, M., Erne, P. Calcium and magnesium binding to rat parvalbumin (1994) Eur J Biochem 222, 21-26.
No information from this reference is currently stored in the database

Ebralidze, A., Tulchimsky, E., Grigorian, M., Afanasyeva, A., Senin, V., Revazova, E., Lukanidin, E. Isolation and characterization of a gene specifically expressed in different metastatic cells and whose deduced gene product has a high degree of homology to a Ca++-binding protein family (1989) Genes and Develop 3, 1086-1093.
View information in the CaBP database derived from this reference

Edgeworth, J. ., Freemont, P. ., Hogg, N. . Ionomycin-regulated phosphorylation of the myeloid calcium-binding protein p14 (1989) Nature 342, 189-192.
No information from this reference is currently stored in the database

Edgeworth, J., Gorman, M., Bennet, R., Freemont, P., Hogg, N. Identification of p8,14, as a highly abundant heterodimeric calcium binding protein complex of myeloid cells (1991) J Biol Chem 266, 7706-7713.
View information in the CaBP database derived from this reference

Edman, C.F, George, S.E, Means, A.R, Schulman, H., Yaswen, P. Selective activation and inhibition of calmodulin-dependent enzymes by a calmodulin-like protein found in human epithelial cells (1994) Eur J Biochem 226, 725-730.
Summary: Calmodulin-like protein was found to activate CaMKII, but not calcineurin, nitric oxide synthase, or smMLCK. In fact, it is a competitive inhibitor of smMLCK activation by calmodulin. Based on their data, the authors propose some interesting speculations about the functional role of calmodulin-like proteins..
View information in the CaBP database derived from this reference

Ehrhardt, M.R, Urbauer, J.L, Wand, A.J The energetics and dynamics of molecular recognition by calmodulin (1995) Biochemistry 34, 2731-2738.
No information from this reference is currently stored in the database

Engelborghs, Y., Mertens, K., Willaert, K., Luan-Rilliet, Y., Cox, J.A Kinetics of conformational changes in Nereis sarcoplasmic calcium-bidning protein upon binding of divalent ions (1990) J Biol Chem 265, 18809-18815.
No information from this reference is currently stored in the database

Englekamp, D. ., Schafer, B.W, Mattei, M.G, Erne, P. ., Heizmann, C.W Six S100 genes are clustered on human chromosome 1q21: identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E. (1993) Proc Natl Acad Sci USA 90, 6547-6551.
No information from this reference is currently stored in the database

Espreafico, E.M, Cheney, R.E, Matteoli, M., Nascimento, A.AC., DeCamilli, P.V, Larson, R.E, Mooseker, M.S Primary structure and cellular localization of chicken brain myosin-V (p190), an unconventional myosin with calmodulin light chains (1992) J Cell Biol 119, 1541-1557.
Summary: Reference about calmodulin binding to unconventional mmyosins via an IQ-motif.
No information from this reference is currently stored in the database

Evenas, J., Thulin, E., Malmendal, A., Forsen, S., Carlstrom, G. NMR studies of the E140Q mutant of the carboxy-terminal domain of calmodulin reveal global conformational exchange in the Ca2+-saturated state (1997) Biochemistry 36, 3448-3457.
Summary: This is the most careful study to date on the effects of mutating the bidentate Glu Ca2+ ligand in a sensor EF-hand protein. The authors conclude that this mutation causes the Ca2+-loaded state to be 60% in the open conformation and 40% in the closed conformation.
No information from this reference is currently stored in the database

Falke, J.J, Drake, S.K, Hazard, A.L, Peersen, O.B Molecular tuning of ion binding to calcium signaling proteins (1994) Quart Rev Biophys 27, 219-290.
No information from this reference is currently stored in the database

Fano, G., Angelella, P., Mariggio, D., Aisa, M.C, Giambanco, I., Donato, R. S-100a0 protein stimulates the basal (Mg2+-activated) adenylate cyclase activity associated with skeletal muscle membranes (1989) FEBS Lett 248, 9-12.
View information in the CaBP database derived from this reference

Fano, G., Marsili, V., Angelella, P., Aisa, M.C, Giambanco, I., Donato, R. S100a0 protein stimulates Ca2+-induced Ca2+ release from isolated sarcoplasmic reticulum vesicles (1989) FEBS Lett 255, 381-384.
View information in the CaBP database derived from this reference

Farah, C.S, Miyamoto, C.A, Ramos, C.HI., da Silva, A.CR., Quaggio, R.B, Fujimori, K., Smilie, L.B, Reinach, F.C Structural and regulatory functions of the NH2- and COOH-terminal regions of skeletal muscle troponin I (1994) J Biol Chem 269, 5230-5240.
No information from this reference is currently stored in the database

Farah, C.S, Reinach, F.C The troponin complex and regulation of muscle contraction (1995) FASEB J 9, 755-767.
No information from this reference is currently stored in the database

Farnsworth, C.L, Freshney, N.W, Rosen, L.B, Ghosh, A., Greenberg, M.E, Feig, L.A Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF (1995) Nature 376, 524-527.
Summary: Ras-GRF, a form of Ras thought to be neuron-specifc, is activated by Ca2+ influx. this seems to be mediated by ca2+-dependent binding of CaM to Ras-GRF. The binding of CaM requires an intact IQ motif. However, this IQ motif in Ras-GRF is not exactly like the consensus sequence..
No information from this reference is currently stored in the database

Feher, J.J Facilitated calcium diffusion by intestinal calcium-binding protein (1983) Am J Physiol 244C, 303-307.
View information in the CaBP database derived from this reference

Ferrari, S., Calabretta, B., deRies, J.K, Battin, R., Ghezzo, F., Lauret, E., Griffin, C., Emanuel, B., Gurrieri, F., Baserga, R. Structural and functional analysis of a growth-regulated gene, the human calcyclin (1987) J Biol Chem 262, 8325-8332.
No information from this reference is currently stored in the database

Filipek, A. ., Kuznicki, J. . Molecular cloning and expression of a mouse brain cDNA encoding a novel protein target of calcyclin (1998) J Neurochem 70, 1793-1798.
No information from this reference is currently stored in the database

Filipek, A. ., Wodja, U. ., Lesniak, W. . Interaction of calcyclin and its cyanogen bromide fragments with annexin II and glyceraldehyde 3-phosphate dehydrogenase (1995) Int J Biochem Cell Biol 27, 1123-1131.
No information from this reference is currently stored in the database

Filipek, A. ., Wojda, U. . p30, a novel protein target of mouse calcyclin (S100A6) (1996) Biochem J 320, 585-587.
No information from this reference is currently stored in the database

Filipek, A., Kuznicki, J. Calcyclin-- from basic research to clinical implications (1993) Acta Biochim Pol 40, 321-327.
View information in the CaBP database derived from this reference

Filipek, A., Puzianowska, M., Cieslak, B., Kuznicki, J. Calcyclin--Ca2+-binding protein homologous to glial S-100 beta is present in neurones (1993) Neuroreport 4, 383-386.
View information in the CaBP database derived from this reference

Findlay, W.A, Martin, S.M, Beckingham, K., Bayley, P.M Recovery of native structure by calcium binding site mutants of calmodulin upon binding of sk-MLCK target peptides (1995) Biochemistry 34, 2087-2094.
No information from this reference is currently stored in the database

Findlay, W.A, Sonnichsen, F.D, Sykes, B.D Solution structure of Tr1C fragment of skeletal muscle troponin C (1994) J Biol Chem 223, 601-606.
View information in the CaBP database derived from this reference

Finn, B.E, Evenas, J., Crakenberg, T., Waltho, J.P, Thulin, E., Forsen, S. Calcium-induced structural changes and domain autonomy in calmodulin (1995) Nat Struct Biol 2, 777-783.
View information in the CaBP database derived from this reference

Finn, B.E, Forsen, S. The evolving model of calmodulin structure, function and activation (1995) Structure 3, 7-11.
Summary: a minireview.
No information from this reference is currently stored in the database

Finn, B.E, Kordel, J., Thulin, E., Sellers, P., Forsen, S. Dissection of calbindin D9k into two Ca2+-binding subdomains by a combination of mutagenesis and chemical cleavage (1992) FEBS Lett 298, 211-214.
No information from this reference is currently stored in the database

Fischer, R., Koller, M., Flura, M., Mathews, S., Strehler-Page, M.-A., Krebs, J., Penniston, J.T, Carafoli, E., Strehler, E.E Multiple divergent mRNAs code for a single human calmodulin (1988) J Biol Chem 263, 17055-17062.
Summary: Reports the identification and characterization of the third gene for calmodulin in humans. This gene codes for an identical protein as the other two genes, but has an unusually divergent nucleotide sequence and quite different codon usage.
View information in the CaBP database derived from this reference

Fisher, P.J, Prendergast, F.G, Ehrhardt, M.R, Urbauer, J.L, Wand, A.J, Sedarous, S.S, McCormick, D.J, Buckley, P.J Calmodulin interacts with amphiphillic peptides composed of all D-amino acids (1994) Nature 368, 651-653.
Summary: An interesting study in which calmodulin is found to bind to D-peptides, although with a higher off-rate than to L-peptides.
No information from this reference is currently stored in the database

Flaherty, K.M, Zozulya, S., Stryer, L., McKay, D.B Three-dimensional structure of recoverin, a calcium sensor in vision (1993) Cell 75, 709-716.
View information in the CaBP database derived from this reference

Foguel, D., Suarez, M.C, Barbosa, C., Rodrigues, J.JN., Jr., Sorenso, M.M, Smillie, L.B, Silva, J.L Mimicry of the calcium-induced conformational state of troponin C by low temperature under pressure (1996) Proc Natl Acad Sci USA 93, 10642-10646.
No information from this reference is currently stored in the database

Forrest, S. Genetic algorithms: principles of natural selection applied to computation (1993) Science 261, 872-878.
No information from this reference is currently stored in the database

Forsen, S., Kordel, J., Grundstrom, T., Chazin, W.J The molecular anatomy of a calcium-binding protein (1993) Acc Chem Res 26, 7-14.
No information from this reference is currently stored in the database

Forsen, S., Linse, S. Cooperativity: over the Hill (1995) Trends Biochem Sci 20, 495-497.
Summary: A clear and useful discussion of how cooperativity should be defined.
No information from this reference is currently stored in the database

Freemont, P. ., Hogg, N. ., Edgeworth, J. . Sequence identity (1989) Nature 339, 516.
No information from this reference is currently stored in the database

Frishman, D., Heumann, K., Lesk, A., Mewes, H.-W. Comprehensive, comprehensible, distributed and intelligent databases: current status (1998) Bioinformatics 14, 551-561.
Summary: An interesting review of the current level of database integration, with a heavy emphasis on sequence databases.
No information from this reference is currently stored in the database

Fromherz, S., Szent-Gyorgyi, A.G Role of essential light chain EF hand domains in calcium binding and regulation of scallop myosin (1995) Proc Natl Acad Sci USA 92, 7652-7656.
No information from this reference is currently stored in the database

Fruman, D.A, Pai, S.Y, Burakoff, S.J, Bierer, B.E Characterization of a mutant calcineurin A alpha gene expressed by EL4 lymphoma cell (1995) Mol Cell Biol 15, 3857-3863.
No information from this reference is currently stored in the database

Fullmer, C.S, Wasserman, R.H The amino acid sequence of bovine intestinal calcium-binding protein (1981) J Biol Chem 256, 5669-5674.
Summary: The first report of the sequence of calbindin D9k, done at the amino acid level..
No information from this reference is currently stored in the database

Gagne, S., Tsuda, S., Li, M., Smillie, L., Sykes, B. Structures of the troponin C regulatory domains in the apo and calcium-saturated states (1995) Nat Struct Biol 2, 784-789.
View information in the CaBP database derived from this reference

Gagne, S.M, Li, M.X, Sykes, B.D Mechanism of direct coupling between binding and induced structural change in regulatory calcium binding proteins (1997) Biochemistry 36, 4386-4392.
View information in the CaBP database derived from this reference

Galperin, M.Y, Brenner, S.E Using metabolic pathway databases for functional annotation (1998) Trends Genet 14, 332-333.
No information from this reference is currently stored in the database

Gangola, P., Pant, H.C Temperature dependent conformational changes in calmodulin (1983) Biochem Biophys Res Comm 111, 301-305.
No information from this reference is currently stored in the database

Gao, Z.H, Krebs, J., VanBerkum, M.FA., Tang, W.-J., Maune, J.F, Means, A.R, Stull, J.T, Beckingham, K. Activation of four enzymes by two series of calmodulin mutants with point mutations in individual Ca(2+) binding sites (1993) J Biol Chem 268, 20096-20104.
Summary: A study of the ability of CaM mutants in which one of the bidentate Glu ligands has been replaced with Gln or Lys to activate smMLCK, skMLCK, adenyl cyclase, and plasma membrane Ca2+-ATPase.
No information from this reference is currently stored in the database

Garrels, J.I YPD-- A database for proteins of Saccharomyces cerevisiae (1996) Nucleic Acids Res 24, 46-49.
No information from this reference is currently stored in the database

Gellman, S. On the role of methionine residues in the sequence-independent recognition of nonpolar protein surfaces (1991) Biochemistry 30, 6633-6636.
No information from this reference is currently stored in the database

Gendler, S., Cohen, E., Craston, A., Duhig, T., Johnstone, G., Barnes, D. The locus of the polymorphic epithelial mucin (PEC) tumor antigen on chromosome 1q21 shows a high frequency of alteration in primary human breast tumors (1990) Int J Cancer 45, 431-435.
No information from this reference is currently stored in the database

George, S., Su, Z., Fan, D., Wang, S., Johnson, J.D The fourth EF-hand of calmodulin and its helix-loop-helix components: impact on calcium binding and enzyme activation (1996) Biochemistry 35, 8307-8313.
Summary: A study of calcium binding and enzyme activation properties of of several CaM/TnC chimeras and CaM mutants. All changes are in the C terminal domain of CaM. Changes in calcium affinity and off rate, cooperativity, and enzyme activation were observed for all mutants..
View information in the CaBP database derived from this reference

George, S.E, Su, Z., Fan, D., Means, A.R Calmodulin-cardiac troponin C chimeras (1993) J Biol Chem 268, 25213-25220.
No information from this reference is currently stored in the database

George, S.E, VanBerkum, M.FA., Ono, T., Cook, R., Hanley, R.M, Putkey, J.A, Means, A.R Chimeric calmodulin-cardiac troponin C proteins differentially activate calmodulin target enzymes (1990) J Biol Chem 265, 9228-9235.
View information in the CaBP database derived from this reference

Gerke, V. "S100A10" in Guidebook to the Calcium-Binding Proteins, (1996) Oxford University Press, Oxford. 149-151.
No information from this reference is currently stored in the database

Gerke, V. "S100P" in Guidebook to the Calcium-Binding Proteins, M.R.Celio, T.Pauls, B.Schwaller, eds. (1996) Oxford University Press, Oxford. 160.
Summary: A brief chapter summarizing the basic characteristics and properties of S100P.
View information in the CaBP database derived from this reference

Gerke, V., Weber, K. Calcium-dependent conformational changes in the 36-kDa subunit of intestinal protein I related to the cellular 36-kDa target of Rous sarcoma virus tyrosine kinase (1985) J Biol Chem 260, 1688-1695.
View information in the CaBP database derived from this reference

Ghosh, D. . A relational database of transcription factors (1990) Nucleic Acids Res 18, 1749-1756.
No information from this reference is currently stored in the database

Ghosh, D. . Status of the transcription factors database (TFD) (1993) Nucleic Acids Res 21, 3117-3118.
No information from this reference is currently stored in the database

Gibbs, F.EM., Barraclough, R., Platt-Higgins, A., Rudland, P., Wilkinson, M., Parry, E. Immunocytochemical distribution of the calcium-binding protein p9Ka in normal rat tissues: Variation in the cellular location in different tissues (1995) J Histochem Cytochem 42/43, 169-180.
View information in the CaBP database derived from this reference

Giedroc, D.P, Puett, D., Ling, N., Staros, J.V Demonstration by covalent cross-linking of a specific interaction between b-endorphin and calmodulin (1983) J Biol Chem 258, 16-19.
No information from this reference is currently stored in the database

Gietzen, K., Wuthrich, A., Bader, H. R 24571: a new powerful inhibitor of red blood cell Ca(2+)-transport ATPase and of calmodulin-related functions (1981) Biochem Biophys Res Comm 101, 418-425.
No information from this reference is currently stored in the database

Gilli, R., Lafitte, D., Lopez, C., Kilhoffer, M.-C., Makarov, A., Briand, C., Haiech, J. Thermodynamic analysis of calcium and magnesium binding to calmodulin (1998) Biochemistry 37, 5450-5456.
Summary: Presents an analysis of the thermodynamics of Ca2+ and Mg2+ binding to CaM, and interprets the data under the preferenctial pathway (sequential) model of Ca2+ binding to CaM.
No information from this reference is currently stored in the database

Gilson, M.K, Given, J.A, Bush, B.L, McCammon, J.A The statistical-thermodynamic basis for a computation of binding affinities: a critical review (1997) Biophys J 72, 1047-1069.
No information from this reference is currently stored in the database

Gimona, M. ., Lando, Z. ., Dolginov, Y. ., Vanderkerckhove, J. ., Kobayashi, R. ., Sobieszek, A. ., Helfman, D.M Ca2+-dependent interaction of S100A2 with muscle and nonmuscle tropomyosin (1997) J Cell Sci 110, 611-621.
No information from this reference is currently stored in the database

Glazewski, S. ., Chen, C.-C., Silva, A. ., Fox, K. . Requirement for a-CaMKII in experience-dependent plasticity of the barrel cortex (1996) Science 268, 421-423.
View information in the CaBP database derived from this reference

Glenney, . Phospholipid-dependent Ca2+ binding by the 36-kDa tyrosine kinase substrate (calpactin) and its 33-kDa core (1986) J Biol Chem 261, 7247-7252.
View information in the CaBP database derived from this reference

Godzik, A. Counting and classifying possible protein folds (1997) Trends Biotech 15, 147-151.
No information from this reference is currently stored in the database

Godzik, A., Sander, C. Conservation of residue interactions in a family of Ca-binding proteins (1989) Protein Eng 2, 589-596.
No information from this reference is currently stored in the database

Goebeler, M. ., Roth, J. ., Burwinkel, F. ., Vollmer, E. ., Bocker, W. ., Sorg, C. . Expression and complex formation of S100-like proteins MRP8 and MRP14 by macrophages during renal allograft rejection (1994) Transplantation 58, 355-361.
No information from this reference is currently stored in the database

Golitsina, N.L, Kordowska, J. ., Wang, C.-W., Lehrer, S.S Ca2+-dependent binding of calcyclin to muscle tropomyosin (1996) Biochem Biophys Res Comm 220, 360-365.
No information from this reference is currently stored in the database

Goll, D.E, Thompson, V.F, Taylor, R.G, Zalewska, T. Is calpain activity regulate by membranes and autolysis or by calcium and calpastatin? (1992) BioEssays 14, 549-556.
Summary: A review arguing that the hypothesis that calpain is regulated by mebranes and autolysis is unable to explain all of the experimental data..
No information from this reference is currently stored in the database

Gopalakrishna, R., Anderson, W.B Ca(2+)-induced hydrophobic site on calmodulin: application for purification by phenyl-sepharose chromatography (1982) Biochem Biophys Res Comm 104, 830-836.
No information from this reference is currently stored in the database

Gopalakrishna, R., Anderson, W.B The effects of chemical modification of calmodulin on Ca(2+)-induced exposure of hydrophobic region. Separation of active and inactive forms of calmodulin (1985) Biochim Biophys Acta 844, 265-269.
No information from this reference is currently stored in the database

Gopalkrishna, R., Anderson, W.B The effects of chemical modification of calmodulin on Ca(2+)-induced exposure of a hydrophobic region. Separation of active and inactive forms of calmodulin (1985) Biochim Biophys Acta 844, 265-269.
No information from this reference is currently stored in the database

Gottesman, S. Genetics of proteolysis in Escherichia coli (1989) Annu Rev Genet 23, 163-198.
No information from this reference is currently stored in the database

Grabarek, Z., Tan, R.-Y., Wang, J., Tao, T., Gergely, J. Inhibition of mutant troponin C activity by an intra-domain disulphide bind (1990) Nature 345, 132-135.
No information from this reference is currently stored in the database

Grabarek, Z., Tao, T., Gergely, J. Molecular mechanism of troponin C function (1992) J Musc Res Cell Motil 13, 383-393.
No information from this reference is currently stored in the database

Greaser, M.L, Gergely, J. Reconstitution of troponin activity from three protein components (1971) J Biol Chem 246, 4226-4233.
No information from this reference is currently stored in the database

Griffin, W.S, Yeralan, O., Sheng, J.G, Boop, F.A, Mrak, R.E, Rovnaghi, C.R, Burnett, B.A, Feoktistova, A., Van Eldik, L.J Overexpression of the neurotrophic cytokine S100 beta in human temporal lobe epilepsy (1995) J Neurochem 65, 228-233.
View information in the CaBP database derived from this reference

Griffith, J.P, Kim, J.L, Kim, E.E, Sintchak, M.D, Thomson, J.A, Fitzgibbon, M.J, Fleming, M.A, Caron, P.R, Hsiao, K., Navia, M.A X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKB12-FK506 complex (1995) Cell 82, 507-522.
Summary: The paper for PDB entry 1TCO.
View information in the CaBP database derived from this reference

Groves, P., Finn, B.E, Kuznicki, J., Forsen, S. A model for target proteins binding to calcium-activated S100 dimers1 (1998) FEBS Lett 421, 175-179.
Summary: Presents a hypothesis about the mode by which S100 proteins interact with targets based on a mutant of calbindin D9k with an insertion in the linker loop.
No information from this reference is currently stored in the database

Groves, P., Linse, S., Thulin, E., Forsen, S. A calbindin D9k mutant containing a novel structural extension: (1)H nuclear magentic resonance studies (1997) Protein Sci 6, 323-330.
No information from this reference is currently stored in the database

Grzesiek, S., Bax, A. The importance of not saturating H2O in protein NMR. Application to sensitivity-enhancement and NOE measurements (1993) J Am Chem Soc 115, 12593-12594.
No information from this reference is currently stored in the database

Guerini, D. "Calcineurin" in Guidebook to the Calcium-Binding Proteins, M.R.Celio, T.Pauls, B.Schwaller, eds. (1996) Oxford University Press, Oxford. 30-32.
Summary: A brief review summarizing the basic properties and characteristics of calcineurin.
No information from this reference is currently stored in the database

Guerini, D. Calcineurin: Not just a simple protein phosphatase (1997) Biochem Biophys Res Comm 235, 271-275.
No information from this reference is currently stored in the database

Guerini, D., Krebs, J., Carafoli, E. Stimulation of the erythrocyte Ca(2+)-ATPase and of bovine brain cyclic nucleotide phosphodiesterase by chemically modified calmodulin (1987) Eur J Biochem 170, 35-42.
View information in the CaBP database derived from this reference

Guignard, F., Mauel, J., Markert, M. Identification and characterization of a novel human neutrophil protein related to the S100 family (1995) Biochem J 309, 395-401.
View information in the CaBP database derived from this reference

Guntert, P. ., Braun, W. ., Wuthrich, K. . Efficient computation of three-dimensional protein structures in solution from nuclear magnetic resonance data using the program DIANA and the supporting programs CALIBA, HABAS and GLOMSA (1991) J Mol Biol 217, 517-530.
No information from this reference is currently stored in the database

Hagens, G., Masouye, I., Augsburger, E., Hotz, R., Saurat, J.-H., Sigenthaler, G. Calcium-binding protein S100A7 and epidermal-type fatty acid-binding protein are associated in the cytosol of human keratinocytes (1999) Biochem J 339, 419-427.
View information in the CaBP database derived from this reference

Haiech, J., Derancourt, J., Pechere, J.-F., Demaille, J.G Magnesium and calcium binding to parvalbumins: Evidence for differences between parvalbumins and an explanation of their relaxing function (1979) Biochemistry 18, 2752-2758.
No information from this reference is currently stored in the database

Haiech, J., Kilhoffer, M.-C., Lukas, T.J, Craig, T.A, Roberts, D.M, Watterson, D.M Restoration of calcium binding activity of mutant clmodulins toward normal by presence of a calmodulin binding strucutre (1991) J Biol Chem 266, 3427-3431.
No information from this reference is currently stored in the database

Hanson, P.I, Schulman, H. Neuronal Ca(2+)/calmodulin-dependent protein kinases (1992) Annu Rev Biochemistry 61, 559-601.
No information from this reference is currently stored in the database

Harder, T., Gerke, V. The subcellular distribution of early endosomes is affected by the annexin II(2)p11(2) complex (1993) J Cell Biol 123, 1119-1132.
View information in the CaBP database derived from this reference

Harper, J.F, Sussman, M.R, Schaller, G.E, Putnam-Evans, C., Charbonneau, H., Harmon, A.C A calcium-dependent protein kinase with a regulatory domain similar to calmodulin (1993) Science 252, 951-954.
Summary: The first report of a clone of CDPK.
No information from this reference is currently stored in the database

Harris, E., Watterson, D.M, Thorner, J. Functional consequences in yeast of single-residue alterations in a consensus calmodulin (1994) J Cell Sci 107, 3235-3249.
No information from this reference is currently stored in the database

Harris, E., Yaswen, P., Thorner, J. Gain-of-function mutations in a human calmodulin-like protein identify residues critical for calmodulin action in yeast (1995) Mol Gen Genet 247, 137-147.
No information from this reference is currently stored in the database

Hart, K.W, Searls, D.B, Overton, G.C SORTEZ: A relational translator for NCBI's ASN.1 database (1994) CABIOS 10, 369-378.
No information from this reference is currently stored in the database

Havel, T.F, Kuntz, I.D, Crippen, G.M The effect of distance constraints on macromolecular conformation II. Simulation of experimental results and theoretical predictions (1979) Biopolymers 18, 73-82.
No information from this reference is currently stored in the database

Haverstick, D.M, Densmore, J.J, Gray, L.S Calmodulin regulation of Ca2+ entry in Jurkat T cells (1998) Cell Calcium 23, 361-367.
No information from this reference is currently stored in the database

Head, J.F "Squidulin" in Guidebook to the Calcium-Binding Proteins, M.R.Celio, T.Pauls, B.Schwaller, eds. (1996) Oxford University Press, Oxford. 84-85.
Summary: A brief chapter summarizing the basic properties and characteristics of squidulin.
View information in the CaBP database derived from this reference

Hebert, S.C, Brown, E.M The extracellualr calcium receptor (1995) Curr Opin Cell Biol 7, 484-492.
No information from this reference is currently stored in the database

Heidorn, D.B, Trewhalla, J. Comparison of the crystal and solution structures of calmodulin and troponin C (1988) Biochemistry 27, 909-915.
No information from this reference is currently stored in the database

Heizmann, C.W, Braun, K. Changes in Ca2+-binding proteins in human neurodegenerative disorders (1992) Trends Neurosci 15, 259-264.
Summary: Summarizes current knowledge about the role of parvalbumin and calbindin D28k in protecting the brain from damage.
No information from this reference is currently stored in the database

Heizmann, C.W, Hunziker, W. Intracellular calcium-binding proteins: more sites than insights (1991) Trends Biochem Sci 16, 98-103.
Summary: A general survey, from a mainly biological viewpoint.
No information from this reference is currently stored in the database

Helms, V. ., McCammon, J.A Kinase conformations: A computational study on the effect of ligand binding (1997) Protein Sci 6, 2336-2343.
No information from this reference is currently stored in the database

Henikoff, S., Henikoff, J.G Embedding strategies for effective use of information from multiple sequence algnments (1997) Protein Sci 6, 698-705.
No information from this reference is currently stored in the database

Hennessey, J.PN., Jr., Manavalan, P., Johnson, W.CN., Jr., Malencik, D.A, Anderson, S.R, Schimerlik, M.I, Shalitin, Y. Conformational transistions of calmodulin as studied by vacuum-UV CD (1987) Biopolymers 26, 561-571.
No information from this reference is currently stored in the database

Hermann, A., Cox, J.A Sarcoplasmic calcium-binding protein (1995) Comp Biochem Physiol B Biochem Mol Biol 111, 337-345.
View information in the CaBP database derived from this reference

Hersmdorf, C.L, Bronner, F. Vitamin D-dependent calcium-binding protein from rat kidney (1985) Biochim Biophys Acta 379, 553-561.
No information from this reference is currently stored in the database

Herzberg, O., James, M. Refined crystal structure of troponin C from turkey skeletal muscle at 2.o angstroms resolution (1988) J Mol Biol 203, 761-779.
No information from this reference is currently stored in the database

Herzberg, O., James, M.NG. Structure of the calcium regulatory muscle protein troponin-C at 2.8 A resolution (1985) Nature 313, 653-659.
No information from this reference is currently stored in the database

Herzberg, O., Moult, J., James, M.NG. A model for the Ca(2+)-induced conformational transition of troponin C (1986) J Biol Chem 261, 2638-2644.
Summary: The original paper on what became known as the HMJ model of TnC/CaM structure and function..
No information from this reference is currently stored in the database

Hessian, P.A, Edgeworth, J., Hogg, N. MRP-8 and MRP-14, two abundant Ca2+-binding proteins of neutrophils and monocytes (1993) J Leuk Biol 53, 197-204.
Summary: A fairly useful review of the current knowledge about the localization, function, and other biological characteristics of MRP-8 and -14..
View information in the CaBP database derived from this reference

Hessian, P.A, Wilkinson, L. ., Hogg, N. . The S100 family protein MRP-14 (S100A9) has homology with the contact domain of high molecular weight kininogen (1995) FEBS Lett 371, 271-275.
No information from this reference is currently stored in the database

Hidaka, H., Asano, M., Tanaka, T. Activity-structure relationship of calmodulin antagonists: napthalene derivatives (1981) Mol Pharmacol 20, 571-578.
No information from this reference is currently stored in the database

Hidaka, H., Endo, T., Kawamoto, S., Yamada, E., Umekawa, H., Tanabe, K., Hara, K. Purification and characterization of adipose tissue S-100b protein (1983) J Biol Chem 258, 2705-2709.
View information in the CaBP database derived from this reference

Hilt, D.C, Kligman, D. "The S-100 protein family: a biochemical and functional overview" in Novel Calcium Binding Proteins, C.W.Heizmann, ed. (1991) Springer-Verlag, New York. 65-103.
Summary: A slightly out of date but very comprehensive review.
View information in the CaBP database derived from this reference

Hinrichsen, R.D Calcium and calmodulin in the control of cellular behavior and motility (1993) Biochim Biophys Acta 1155, 277-293.
Summary: good review of biological functions of calmodulin.
No information from this reference is currently stored in the database

Hirschhorn, R., Aller, P., Yuan, Z.-A., Gibson, C., Baserga, R. Cell cycle specific cDNAs from mammalian cells temperature sensitive for growth (1984) Proc Natl Acad Sci USA 81, 6004-6008.
No information from this reference is currently stored in the database

Hohenester, E., Maurer, P., Hohenadl, C., Timpl, R., Jansonius, J.N, Engel, J. Structure of a novel extracellular Ca2+-binding module in BM-40 (1996) Nat Struct Biol 3, 67-73.
View information in the CaBP database derived from this reference

Hohenester, E., Maurer, P., Timpl, R. Crystal structure of a pair of follistatin-like and EF-hand calcium-binding domains in BM-40 (1997) EMBO J 16, 3778-3786.
Summary: The paper for PDB entry 1BMO.
View information in the CaBP database derived from this reference

Holm, L., Sander, C. Dictionary of recurrent domains in protein structures (1998) Proteins 33, 88-96.
Summary: Reports an automatic method for generating a "dictionary" of protein domains, and describes the dictionary resulting from analysis of a representative set of structures.
No information from this reference is currently stored in the database

Houdusse, A., Cohen, C. Structure of the regulatory domain of scallop myosin at 2 angstrom resolution: implications for regulation (1996) Structure 4, 21-32.
Summary: Structure of scallop myosin light cahins and portion of the heavy chain. Discusses unusual calcium coordination seen in the ELC. Compares with previously solved chicken skeletal myosin structure.
View information in the CaBP database derived from this reference

Houdusse, A., Love, M.L, Dominguez, R., Grabarek, Z., Cohen, C. Structures of four Ca2+-bound troponin C at 2.0 angstrom resolution: further insights into the Ca2+-switch in the calmodulin superfamily (1997) Structure 5, 1695-1711.
Summary: .
View information in the CaBP database derived from this reference

Houdusse, A., Silver, M., Cohen, C. A model of Ca(2+)-free calmodulin binding to unconventional myosins reveals how calmodulin acts as a regulatory switch (1996) Structure 4, 1475-1490.
Summary: Describes a model of calmodulin bound to unconventional myosin based on the structure of scallop myosin regulatory domain. The C-terminal domain of calmodulin is modeled in the semi-open conformation. This model is used to propose which residues in the IQ motif are essential for binding to a CaBP domain in the semi-open conformation.
No information from this reference is currently stored in the database

Howard, A., Legon, S., Spurr, N.K, Walters, J.RF. Molecular cloning and chromosomal assignment of human calbindin-D9k (1992) Biochem Biophys Res Comm 185, 663-669.
View information in the CaBP database derived from this reference

Huang, B., Watterson, D.M, Lee, V.D, Shibler, M.J Purification and characterization of a basal body-associated Ca(2+)-binding protein (1988) J Cell Biol 107, 121-131.
View information in the CaBP database derived from this reference

Hunter, M.J, Chazin, W.J High level expression and dimer characterization of the S100 EF-hand proteins, migration inhibitory factor-related proteins 8 and 14 (1998) J Biol Chem 273, 12427-12435.
View information in the CaBP database derived from this reference

Huque, M.E, Vogel, H.J Carbon-13 NMR studies of the lysine side chains of calmodulin and its proteolytic fragments (1993) J Prot Chem 12, 695-707.
No information from this reference is currently stored in the database

Hutnik, C.ML., MacManus, J.P, Banville, D., Szabo, A.G Comparison of metal ion-induced conformational changes in parvalbumin and ocomodulin as probed by the intrinsic fluorescence of tryptophan 102 (1990) J Biol Chem 265, 11456-11464.
No information from this reference is currently stored in the database

Hutnik, C.ML., MacManus, J.P, Banville, D., Szabo, A.G Metal-induced changes in the fluorescence properties of tyrosine and tryptophan site-specific mutants of oncomodulin (1991) Biochemistry 30, 7652-7660.
No information from this reference is currently stored in the database

Hutnik, C.ML., MacManus, J.P, Szabo, A.G A calcium-specific conformationsl response of parvalbumin (1990) Biochemistry 29, 7318-7328.
No information from this reference is currently stored in the database

Iida, S., Potter, J.D Calcium binding to calmodulin. Cooperativity of the calcium-binding sites (1986) J Biochem 99, 1765-1772.
No information from this reference is currently stored in the database

Ikura, M. Calcium binding and conformational response in EF-hand proteins (1996) Trends Biochem Sci 21, 14-17.
Summary: Introduction to the differences between EF hand proteins with "sensor" and "buffer" functions.
No information from this reference is currently stored in the database

Ikura, M., Clore, G.M, Gronenborn, A.M, Zhu, G., Klee, C.B, Bax, A. Solution structure of a calmodulin-target peptide complex by multidimensional NMR (1992) Science 256, 632-638.
View information in the CaBP database derived from this reference

Ikura, M., Kay, L.E, Bax, A. A novel approach for sequential assignment of 1H,13C and 15N spectra of larger proteins: Heteronuclear triple-resonance three-dimensional NMR spectroscopy. Application to calmodulin (1990) Biochemistry 29, 4659-466.
No information from this reference is currently stored in the database

Ikura, M., Spera, S., Barbato, G., Kay, L.E, Krinks, M., Bax, A. Secondary structure and side-chain 1H and 13C resonance assignments of calmodulin in solution by heteronuclear multidimensional NMR spectroscopy (1991) Biochemistry 30, 9216-9228.
No information from this reference is currently stored in the database

Ilg, E.C, Schafer, B.W, Heizmann, C.W Expression pattern of S100 calcium-binding proteins in human tumors (1996) Int J Cancer 68, 325-332.
No information from this reference is currently stored in the database

Inaguma, Y., Kurobe, N., Shinohara, H., Kato, K. Sensitive immunoassay for rat parvalbumin: tissue distribution and developmental changes (1991) Biochim Biophys Acta 1075, 68-74.
View information in the CaBP database derived from this reference

Islam, S.A, Sternberg, M.JE. A relational database of protein structures designed for flexible enquires about conformation (1989) Protein Eng 2, 431-442.
Summary: Describes the design and implementation of a relational database containing a range of information about crystal structures.
No information from this reference is currently stored in the database

Jackson, A.E, Puett, D. Binding of trifluoperazine and fluorene-containing compounds to calmodulin and adducts (1986) Biochem Pharmacol 35, 4395-4400.
No information from this reference is currently stored in the database

Janin, J., Wodak, S. Conformation of amino acid side-chains in proteins (1978) J Mol Biol 125, 357-386.
No information from this reference is currently stored in the database

Jansco, A., Szent-Gyorgyi, A.G Regulation of scallop myosin by the regulatory light chain depends on a single glycine residue (1994) Proc Natl Acad Sci USA 91, 8762-8766.
No information from this reference is currently stored in the database

Jiang, H., Shah, S., Hilt, D.C Organization, sequence, and expression of the murine S100B gene (1993) J Biol Chem 268, 20502-20511.
View information in the CaBP database derived from this reference

Johansson, C., Brodin, P., Grundstrom, T., Forsen, S., Drakenberg, T. Mutation of the pseudo-EF hand of calbindin D9k into a normal EF hand: biophysical studies (1991) Eur J Biochem 202, 1283-1290.
Summary: A series of mutants were made in an attempt to turn the pseudo-EF hand loop into a canonical one. One mutant (A14 removed+A15D+P20G+N21 removed) seems to do this, but cooperativity is lost..
View information in the CaBP database derived from this reference

Johansson, C., Brodin, P., Grundstrom, T., Thulin, E., Forsen, S., Drakenberg, T. Biophysical studies of engineered mutant proteins based on calbindin D9k modified in the pseudo EF-hand (1990) Eur J Biochem 187, 455-460.
No information from this reference is currently stored in the database

Johansson, C., Ullner, M., Drakenberg, T. The solution structures of mutant calbindin D9kıs, as determined by NMR, show that the calcium-binding site can adopt different folds. (1993) Biochemistry 32, 8429-8438.
Summary: Report of the NMR structure of a mutant calbindin in which the N terminal binding loop is converted from a pseudo-EF hand to a canonical fold. The mutant is A14 removed+A15D+P20G+N21 removed+P43M. The calcium-loaded state of this mutant is found to have the same global fold (³closed²) as the wildtype protein. The proton assignments indicate that the mutant A14 removed+P20G+N21 removed also adopts the canonical fold..
View information in the CaBP database derived from this reference

Joyal, J.L, Annan, R.A, Ho, Y.D, Huddleston, M.E, Carr, S.A, Hart, M.J, Sacks, D.B Calmodulin modulates the interaction between IQGAP1 and Cdc42:Identification of IQGAP1 by nanoelectrospray tandem mass spectroscopy (1997) J Biol Chem 272, 15419-15425.
View information in the CaBP database derived from this reference

Joyal, J.L, Burks, D.J, Pons, S., Matter, W.F, Vlahos, C.J, White, M.F, Sacks, D.B Calmodulin activates phosphatidylinositol 3-kinase (1997) J Biol Chem 272, 28183-28186.
View information in the CaBP database derived from this reference

Julenius, K., Thulin, E., Linse, S., Finn, B.E Hydrophobic core substitutions in calbindin D9k: effects on stability and structure (1998) Biochemistry 37, 8915-8925.
View information in the CaBP database derived from this reference

Kahn, R., Fourme, R., Bosshard, R., Chiadmi, M., Risler, J.L, Dideberg, O., Wery, J.P Crystal structure study of Opsanus tau parvalbumin by multiwavelength anomalous diffraction (1985) FEBS Lett 179, 133-137.
Summary: Tb is substituted for Ca.
View information in the CaBP database derived from this reference

Kakalis, L.T, Kennedy, M., Sikkin, R., Rusnak, F., Armitage, I.M Characterization of the calcium-binding sites of calcineurin B (1995) FEBS Lett 362, 55-58.
No information from this reference is currently stored in the database

Kalabokis, V.N, O'Neall-Hennessey, E., Szent-Gyorgyi, A.G Regulatory domains of myosins: influence of heavy chain on Ca2+-binding (1994) J Musc Res Cell Motil 15, 547-553.
No information from this reference is currently stored in the database

Kaptein, R., Zuiderweg, E.RP., Scheek, R.M, Boelens, R., vanGunsteren, W.F A protein structure from nuclear magnetic resonance data. Lac repressor headpiece (1985) J Mol Biol 182, 179-182.
No information from this reference is currently stored in the database

Karplus, P.A Hydrophobicity regained (1997) Protein Sci 6, 1302-1307.
Summary: An examination of the true meaning of studies of the partition of amino acids into non-aqueous solvents, and an explanation of a more accurate hydrophobicity scale.
No information from this reference is currently stored in the database

Kataoka, M., Head, J.F, Seaton, B.A, Engelman, D.M Melittin binding causes a large calcium-dependent conformational change in calmodulin (1989) Proc Natl Acad Sci USA 86, 6944-6948.
No information from this reference is currently stored in the database

Kawasaki, H., Kretsinger, R.H Calcium-binding Proteins 1:EF-hands (1995) Protein Profile 2, 305-490.
No information from this reference is currently stored in the database

Kay, L.E, Ikura, M., Zhu, G., Bax, A. Four-dimensional heteronuclear triple-resonance NMR of isotopically enriched proteins for sequential assignment of backbone atoms (1991) J Magn Reson 91, 422-428.
No information from this reference is currently stored in the database

Kay, L.E, Torchia, D., Bax, A. Backbone dynamics of proteins as studied by 15N inverse detected heteronuclear NMR spectroscopy: application to staphylococcal nuclease (1989) Biochemistry 28, 8972-8979.
No information from this reference is currently stored in the database

Kelly, J.W Amyloid fibril formation and protein misassembly: a structural quest for insights into amyloid and prion disease (1997) Structure 5, 595-600.
No information from this reference is currently stored in the database

Kennedy, M.T, Brockman, H., Rusnak, F. Contributions of myristoylation to calcineurin structure/function (1996) J Biol Chem 271, 26517-26521.
No information from this reference is currently stored in the database

Kesvatera, T., Jonsson, B., Thulin, E., Linse, S. Binding of Ca(2+) to calbindin D9k: structural stability and function at high salt concentration (1994) Biochemistry 33, 14170-14176.
Summary: Calbindin retains its structure and ability to bind calcium in 1M KCl. Studies with high salt and charge-neutralizing mutations indicate that cooperativity of calcium binding is greatly influenced by electrostatics..
No information from this reference is currently stored in the database

Kilby, P.M, Van Eldik, L.J, Roberts, G.CK. The solution structure of the bovine S100B protein dimer in the calcium-free state (1996) Structure 4, 1041-1052.
Summary: The paper for PDB entry 1CFP.
View information in the CaBP database derived from this reference

Kilhoffer, M.-C., Kubina, M., Travers, F., Haiech, J. Use of engineered proteins with internal tryptophan reporter groups and perturbation techniques to probe the mechanism of ligan-protein interactions: investigation of the mechanism of calcium-binding to calmodulin (1992) Biochemistry 31, 8098-8106.
No information from this reference is currently stored in the database

Kindy, M.S, Brown, K.E, Sonnenshein, G.E Regulation of expression of the growth-state-related genes 2F1 and 2A9 during entruy of quiescent smooth muscle cells into the cell cycle (1991) J Cell Biochem 46, 345-350.
No information from this reference is currently stored in the database

Kirkpatrick, S., Gelatt, C.DN., Jr., Vecchi, M.P Optimization by simulated annealing (1983) Science 220, 671-680.
No information from this reference is currently stored in the database

Kissinger, C.R, Parge, H.E, Knighton, D.R, Lewis, C.T, Pelletier, L.A, Tempczyk, A., Kalish, V.J, Tucker, K.D, Showalter, R.E, Moomaw, E.W, Gastinel, L.N, Habuka, N., Chen, X., Maldonado, F., Barker, J.E, Bacquet, R., Villafranca, J.E Crystal structures of human calcineurin and the human FKBp12-FK506-calcineurin complex (1995) Nature 378, 641-644.
Summary: The paper for PDB entry 1AUI.
No information from this reference is currently stored in the database

Klee, C.B, Draetta, G.F, Hubbard, M.J Calcineurin (1988) Adv Enzymol 61, 149-200.
No information from this reference is currently stored in the database

Klee, C.B, Krinks, M.H Purification of cyclic 3ı,5ı-nucleotide phosphodiesterase inhibitory protein by affinity chromotography on activator protein coupled to sepharose (1978) Biochemistry 17, 120-126.
No information from this reference is currently stored in the database

Klein, J.R, Hoon, D.SB., Nangauyan, J., Okun, E., Cochran, A.J S-100 protein stimulates cellular proliferation (1989) Cancer Immunol Immunother 29, 133-138.
View information in the CaBP database derived from this reference

Klempt, M., Melkonyan, H., Nacken, W., Wiesmann, D., Holtkemper, U., Sorg, C. The heterodimer of Ca2+-binding proteins MRP8 and MRP14 binds arachidonic acid (1997) FEBS Lett 408, 81-84.
Summary: Presents evidence that the MRP8/MRP14 heterodimer interactic with arachidomic acid in a calcium-dependent manner..
View information in the CaBP database derived from this reference

Klenchin, V.A, Calvert, P.D, Bownds, M.D Inhibition of rhodopsin kinase by recoverin (1995) J Biol Chem 270, 16147-16152.
Summary: This paper reports on the inhibition of phophorylation of rhodopsin by calcium-loaded recoverin, most likely by direct inhibition of rhodopsin kinase. Extrapolation of in vitro measurements of the calcium affinity of recoverin to physiological conditions indicates that the inhibition of rhodopsin kinase by calcium-loaded recoverin is physiologically relevent..
View information in the CaBP database derived from this reference

Kordel, J., Forsen, S., Drakenberg, T., Chazin, W.J The rate and structural consequences of proline cis-trans isomerization in calbindin D9k: NMR studies of the minor (Cis-Pro43) isoform and the Pro43Gly mutant (1990) Biochemistry 29, 4000-4009.
View information in the CaBP database derived from this reference

Kordel, J., Pearlman, D.A, Chazin, W.J Protein solution structure calculations in solution: Solvated molecular dynamics refinement of calbindin D9k (1997) J Biomol NMR 10, 231-243.
View information in the CaBP database derived from this reference

Kordel, J., Skelton, N., Akke, M., Chazin, W.J High resolution solution structure of calcium-loaded calbindin D9k (1993) J Mol Biol 231, 711-734.
Summary: Presents the solution structure of calcium loaded calbindin and makes a useful comparison with the crystal structure.
View information in the CaBP database derived from this reference

Kordel, J., Skelton, N.J, Akke, M., Palmer, A.G, Chazin, W.J Backbone dynamics of calcium-loaded calbindin D9k studied by two-dimensional proton-detected 15N NMR spectroscopy (1992) Biochemistry 31, 4856-4866.
No information from this reference is currently stored in the database

Kragelund, B.B, Jonsson, M., Bifulco, G., Chazin, W.J, Nilsson, H., Finn, B.E, Linse, S. Hydrophobic core substitution in calbindin D9k: Effects on Ca2+ binding and dissociation (1998) Biochemistry 37, 8926-8937.
View information in the CaBP database derived from this reference

Krebs, J., Quadroni, M., VanEdlik, L.J Dance of the Dimers (1995) Nat Struct Biol 2, 711-714.
No information from this reference is currently stored in the database

Kretsinger, R.H EF-hands reach out (1996) Nat Struct Biol 3, 12-15.
No information from this reference is currently stored in the database

Kretsinger, R.H, Nockolds, C.E Carp muscle calcium-binding protein: II. structure determination and general description (1973) J Biol Chem 248, 3313-3326.
No information from this reference is currently stored in the database

Krieger, C., Lanius, R.A, Pelech, S.L, Shaw, C.A Amyotrophic lateral sclerosis: the involvement of intracellular Ca(2+) and protein kinase C (1996) Trends Pharmacol Sci 17, 114-120.
No information from this reference is currently stored in the database

Kube, E. ., Becker, T. ., Weber, K. ., Gerke, V. . Protein-protein interaction studied by site-directed mutagenesis. Characterization of the annexin II-binding site on p11, a member of the S100 protein family (1992) J Biol Chem 267, 14175-14182.
No information from this reference is currently stored in the database

Kuboniwa, H., Tjandra, N., Grzesiek, S., Ren, H., Klee, C.B, Bax, A. Solution structure of calcium-free calmodulin (1995) Nat Struct Biol 2, 768-776.
View information in the CaBP database derived from this reference

Kumar, V.D, Lee, L., Edwards, B.FP. Refined crystal structure of calcium-liganded carp parvalbumin 4.25 at 1.5-angstrom resolution (1990) Biochemistry 29, 1404-1412.
View information in the CaBP database derived from this reference

Kumar, V.D, Lee, L., Edwards, B.FP. Refined crystal structure of ytterbium-substituted carp parvalbumin 4.25 at 1.5 angstrom, and its comparison with the native and cadmium-substituted structures (1991) FEBS Lett 283, 311-316.
No information from this reference is currently stored in the database

Kuznicki, J., Filipek, A. Purification and properties of a novel Ca2+-binding protein (10.5 kDa) from Ehrlich ascites tumor cells (1987) Biochem J 247, 663-667.
View information in the CaBP database derived from this reference

Lackmann, M. ., Rajasekariah, P. ., Iismaa, S.E, Jones, G. ., Cornish, C.J, Hu, S. ., Simpson, R.J, Moritz, R.L, Geczy, C.L Identification of a chemotactic domain of the pro-inflammatory S100 protein CP-10 (1993) J Immunol 150, 1981-2991.
No information from this reference is currently stored in the database

Lackmann, M., Cornish, C.J, Simpson, R.J, Moritz, R.L, Geczy, C.L Purification and structural analysis of a murine chemotactic cytokine (CP-10) with sequence homology to S100 proteins (1992) J Biol Chem 267, 7499-7504.
View information in the CaBP database derived from this reference

Lakshmi, M.S, Parker, C., Shernet, G.V Metastasis associated MTS1 and NM23 genes affect tubulin polymerisation in B16 melanomas: a possible mechanism of their regulation of metastatic behaviour of tumors (1993) Anticancer Res 13, 299-304.
View information in the CaBP database derived from this reference

Landar, A., Caddell, G., Chessher, J., Zimmer, D.B Identification of an S100A1/S100B target protein: phosphoglucomutase (1996) Cell Calcium 20, 279-285.
View information in the CaBP database derived from this reference

Lane, T.F, Sage, E.H The biology of SPARC, a protein that modulates cell-matrix interactions (1994) FASEB J 6, 163-173.
View information in the CaBP database derived from this reference

Lannrgren, J., Elzinga, G., Stienen, G.J Force relaxation, labile heat and parvalbumin content of skeletal muscle fibres of Xenopus laevis (1993) J Physiol 463, 123-140.
View information in the CaBP database derived from this reference

LaPorte, D.C, Wierman, B.M, Storm, D.R Calcium-induced exposure of a hydrophobic surface on calmodulin (1980) Biochemistry 19, 3814-3819.
No information from this reference is currently stored in the database

Lavorgna, G., Boncinelli, E., Wagner, A., Werner, T. Detection of potential target genes in silico? (1998) Trends Genet 14, 375-376.
No information from this reference is currently stored in the database

Lazar, G.A, Desjarlais, J.R, Handel, T.M De novo design of the hydrophobic core of ubiquitin (1997) Protein Sci 6, 1167-1178.
Summary: Describes a program for predicting which sequences in a protein core will result in a stable protein with unique tertiary structure.
No information from this reference is currently stored in the database

Lee, B., Vasmatzis, G. Stabilization of protein strucutres (1997) Curr Opin Biotech 8, 423-428.
Summary: A brief, useful review of recent protein engineering studies about the role of specif types of interactions in protein stability.
No information from this reference is currently stored in the database

Lee, S.-J., Stull, J.T Calmodulin-dependent regulation of inducible and neuronal nitric-oxide synthase (1998) J Biol Chem 273, 27430-27437.
No information from this reference is currently stored in the database

Lee, S.W, Tomasetto, C., Swissheln, L., Keyomarsi, K., Sager, R. Down-regulation of a member of the S100 gene family in mammary carcinoma cells and reexpression by azadeoxycytidine treatment (1992) Proc Natl Acad Sci USA 89, 2504-2508.
View information in the CaBP database derived from this reference

Lee, V.D, Huang, B. Molecular cloning and centrosomal localization of human caltractin (1993) Proc Natl Acad Sci USA 90, 11039-11043.
View information in the CaBP database derived from this reference

Lee, V.D, Stapleton, M., Huang, B. Genomic structure of Chlamydomonas caltractin: evidence for intron insertion suggests a probable genealogy for the EF-hand superfamily of proteins (1991) J Mol Biol 221, 175-191.
View information in the CaBP database derived from this reference

Lee, W. ., Revington, M.J, Arrowsmith, C. ., Kay, L.E A pulsed field gradient isotope-filtered 3D 13C HMQC-NOESY experiment for extracting intermolecular NOE contacts in molecular complexes. (1994) FEBS Lett 350, 87-90.
No information from this reference is currently stored in the database

Lee, Y.C, J Wolff, J. . Two opposing effects of calmodulin on microtubule assembly depend on the presence of microtubule-associated proteins (1982) J Biol Chem 259, 1226-1230.
View information in the CaBP database derived from this reference

Levin, R.M, Weiss, B. Specificity of the binding of trifluoperazine to the calcium-dependent activator of phosphodiesterase and to a series of other calcium-binding proteins (1978) Biochim Biophys Acta 540, 197-204.
No information from this reference is currently stored in the database

Levy, Y.Y, Lai, E.Y, Remillard, S.P, Heintzelman, M.B, Chandler, F. Centrin is a conserved protein that forms diverse associations with centrioles and MTOCs in Naegleria and other organisms (1996) Cell Motil and Cytoskel 33, 298-323.
No information from this reference is currently stored in the database

Li, M.X, Gagne, S.M, Spyracopoulos, L., Loks, C.PA., Audette, G., Chandra, M., Solaro, R.J, Smillie, L.B, Sykes, B.D NMR studies of Ca2+ binding to the regulatory domain of cardiac and E41A skeletal muscle troponin C reveal the importance of site I to energetics of the induced structural change (1997) Biochemistry 36, 12519-12525.
No information from this reference is currently stored in the database

Li, M.X, Gagne, S.M, Tsuda, S., Kay, C.M, Smillie, L.B, Sykes, B.D Calcium binding to the regulatory N-domain of skeletal muscle troponin C occurs in a stepwise manner (1995) Biochemistry 34, 8330-8340.
No information from this reference is currently stored in the database

Liang, S., Fuhrman, S., Somogyi, R. REVEAL, a general reverse engineering algorithm for inference of genetic network architectures (1998) Pacific Symposium on Biocomputing 3, 18-29.
No information from this reference is currently stored in the database

Liemann, S., Lewit-Bentley, A. Annexins: a novel family of calcium- and membrane-binding proteins in search of a function (1995) Structure 3, 233-237.
No information from this reference is currently stored in the database

Lin, G.-d., Chattopdhyaya, D., Masatoshi, M., Wang, K.KW., Carson, M., Jin, L., Yuen, P.-w., Takano, E., Hatanaka, M., DeLucas, L.J, Narayana, S.VL. Crystal structure of calcium bound domain VI of calpain at 1.9 A resolution and its role in enzyme assembly, regulation, and inhibitor binding (1997) Nat Struct Biol 4, 539-547.
View information in the CaBP database derived from this reference

Lin, X., Krudy, G.A, Howarth, J., Brito, R.MM., Rosevear, P.R, Putkey, J.A Assignment and calcium dependence of methionyl (e)C and (e)H resonances in cardiac troponin C (1994) Biochemistry 33, 14434-14442.
No information from this reference is currently stored in the database

Linse, S., Brodin, P., Drakenberg, T., Thulin, E., Sellers, P., Elmden, K., Grundstrom, T., Forsen, S. Structure-function relationships in EF-Hand Ca(2+)-binding proteins. Protein engineering and biophysical studies of calbindin D9k (1987) Biochemistry 26, 6723-6735.
Summary: The mutation of Y13F has no effect on the cooperativity of calcium-binding, although it does affect the macroscopic binding constants..
View information in the CaBP database derived from this reference

Linse, S., Bylsma, N.R, Drakenberg, T., Sellers, P., Forsen, S., Thulin, E. A calbindin D9k mutant with reduced calcium affinity and enhanced cooperativity. Metal ion binding, stability, and structural studies (1994) Biochemistry 33, 12478-12486.
Summary: Mutating glu 60 to asp decreases calcium affinity and increases cooperativity of binding. The decrease in affinity is thought to occur because the shorter asp side chain has a weaker hydrogen bond to the calcium-liganding water molecule thatn the glu side chain had. The reason for the increase in cooperativity is less apparent..
View information in the CaBP database derived from this reference

Linse, S., Forsen, S. Determinants that govern high-affinity calcium binding (1995) Adv Second Messenger Phosphoprotein Res 30, 89-151.
Summary: Excellent review of what is known about calcium affinity in EF Hand proteins. Also includes information about other types of calcium binding proteins. Includes a clear and concise background on the physical chemistry of affinity and cooperativity..
No information from this reference is currently stored in the database

Linse, S., Helmersson, A., Forsen, S. Calcium binding to calmodulin and its globular domains (1991) J Biol Chem 266, 8050-8054.
View information in the CaBP database derived from this reference

Linse, S., Johansson, C., Brodin, P., Grundstrom, T., Drakenberg, T., Forsen, S. Electrostatic contributions to the binding of Ca(2+) in calbindin D9k (1991) Biochemistry 30, 154-183.
View information in the CaBP database derived from this reference

Linse, S., Jonsson, B., Chazin, W.J The effect of protein concentration on ion binding (1995) Proc Natl Acad Sci USA 92, 4748-4752.
No information from this reference is currently stored in the database

Linse, S., Teleman, O., Torbjorn, D. Ca(2+) binding to calbindin D9k strongly affects backbone dynamics: measurements of exchange rates of individual amide protons using (1)H-NMR (1990) Biochemistry 29, 5925-5934.
Summary: Reports the measurement of exchange rates for all amide hydrogens in the calcium-loaded form of calbindin and about one-half pf the amide hydrogens in the apo form. In general, the calcium-loaded form has slower exchange..
No information from this reference is currently stored in the database

Linse, S., Thulin, E., Gifford, L.K, Radzewsky, D., Hagan, J., Wilk, R.R, Akerfeldt, K.S Domain organization of calbindin D28k as determined from the association of six synthetic EF-hand fragments (1997) Protein Sci 6, 2385-2396.
Summary: Using peptides of the individual EF-hands in calbindin D28k and a variety of biophysical techniques, the authors present strong evidence that all six EF-hands of calbindin D28k are part of a single domain.
No information from this reference is currently stored in the database

Linse, S., Thulin, E., Selllers, P. Disulfide bonds in homo- and heterodimers of EF-hand subdomains of calbindin D9k: stability, calcium binding, and NMR studies (1993) Protein Sci 2, 985-1000.
View information in the CaBP database derived from this reference

Lipari, F. ., Herscovics, A. . Calcium binding to the class I alpha-1,2,-Mannosidase from Saccharomyces cerevisiae occurs outside the EF hand motif (1999) Biochemistry 38, 1111-1118.
No information from this reference is currently stored in the database

Lipari, G., Szabo, A. Model-free approach to the interpretation of nuclear magnetic resonance relaxation in macromolecules. 1. Theory and range of validity (1982) J Am Chem Soc 104, 4546-4559.
No information from this reference is currently stored in the database

Lipscomb, L.A, Gassner, N.C, Snow, S.D, Eldridge, A.M, Baasa, W.A, Drew, D.L, Matthews, B.W Context-dependent protein stabilization by methionine-to-leucine substitution shown in T4 lysozyme (1998) Protein Sci 7, 765-773.
Summary: A report on the effects of Met to Leu and Met to Lys mutations in T4 lysozyme. Discusses the possibility of predicting which Met to Leu mutation will be stabilizing.
No information from this reference is currently stored in the database

Liu, H. ., Spielmann, P. ., Ulyanov, N.B, Wemmer, D.E, James, T.L Interproton distance bounds from 2D NOE intensities: effect of experimental noise and peak integration errors (1995) J Biomol NMR 6, 390-402.
No information from this reference is currently stored in the database

Liu, J., Farmer, J.DN., Jr., Lane, W.S, Firedman, J., Weissman, I., Schreiber, S.L Calcineurin is a common target of cyclophilin-cyclosporinA and FKBP-FK506 complexes (1991) Cell 66, 807-815.
No information from this reference is currently stored in the database

Liu, Y., Storm, D.R Regulation of free calmodulin levels by neuromodulin: neuron growth and regeneration (1990) Trends Pharmacol Sci 11, 107-111.
Summary: Discussion focuses on the biochemical properties and tissue-specificity of neuromodulin. The interaction of neuromodulin with CaM is also discussed, and a biochemical model is proposed to explain the significance of this interaction..
No information from this reference is currently stored in the database

Loll, P.J, Lattmam, E.E The crystal structure of the ternary complex of Staphylococcal nuclease, Ca2+, and the inhibitor pdTp, refined at 1.65 angstroms (1989) Proteins 5, 183-201.
No information from this reference is currently stored in the database

Loomans, H.J, Hahn, B.L, Li, Q.-L., Phadnis, S.H, Sohnle, P.G Histidine-based zinc-binding sequences and the antimicrobial activity of calprotectin (1998) J Infect Dis 177, 812-814.
No information from this reference is currently stored in the database

Lowenstein, C.J, Snyder, S.H Nitric oxide, a novel biologic messenger (1992) Cell 70, 705-707.
No information from this reference is currently stored in the database

Luan-Rilliet, Y., Milos, M., Cox, J.A Thermodynamics of cation binding to Nereis sarcoplasmic calcium-binding protein (1992) Eur J Biochem 208, 133-138.
No information from this reference is currently stored in the database

Lukas, T.J, Burgess, W.H, Prendergast, F.G, Lau, W., Watterson, D.M Calmodulin binding domains: characterization of a phosphorylation and calmodulin binding site from myosin light chain kinase (1986) Biochemistry 25, 1458-1464.
View information in the CaBP database derived from this reference

Lukas, T.J, Collinge, M., Haiech, J., Watterson, D.M Gain of function mutations for yeast calmodulin and calcium dependent regulation of protein kinase activity (1994) Biochim Biophys Acta 1223, 341-347.
No information from this reference is currently stored in the database

Lyall, A. Bioinformatics in the pharmaceutical industry (1996) Trends Biotech 14, 308-312.
No information from this reference is currently stored in the database

Lytton, J., Nigam, S.K Intracellular calcium: molecules and pools (1992) Curr Opin Cell Biol 4, 220-226.
No information from this reference is currently stored in the database

Macauley, J. ., Wang, H. ., Goodman, N. . A model system for studying the integration of molecular biology databases (1998) Bioinformatics 14, 575-582.
No information from this reference is currently stored in the database

MacManus, J.P, Hutnik, C.ML., Sykes, B.D, Szabo, A.G, Williams, T.C, Banville, D. Characterization and site-specific mutagenesis of the calcium-binding protein oncomodulin produced by recombinant bacteria (1989) J Biol Chem 264, 3470-3477.
No information from this reference is currently stored in the database

Maeda, T., Usui, H., Araki, K., Kuwano, R., Takahashi, Y., Suzuki, Y. Structure and expression of the rat S-100B gene (1991) Mol Brain Res 10, 193-202.
View information in the CaBP database derived from this reference

Malencik, D.A, Anderson, S.R Binding of hormones and neuropeptides by calmodulin (1983) Biochemistry 22, 1995-2001.
No information from this reference is currently stored in the database

Malmendal, A., Carlstrom, G., Hambraeus, C., Drakenberg, T., Forsen, S., Akke, M. Sequence and context dependence of EF-hand loop dynamics. An (15)N relaxation study of a calcium-binding site mutant of calbindin D9k (1998) Biochemistry 37, 2586-2595.
No information from this reference is currently stored in the database

Manalan, A.S, Krinks, M.H, Klee, C.B Calcineurin: a member of a family of calmodulin-stimulated protein phosphatases (41905) (1984) Proc Soc Exp Biol Med 177, 12-16.
No information from this reference is currently stored in the database

Mani, R.S, McCubbin, W.D, Kay, C.M Calcium-dependent regulation of caldesmon by an 11-kDa smooth muscle calcium-binding protein, caltropin (1992) Biochemistry 31, 11896-11901.
View information in the CaBP database derived from this reference

Marchand, S., Roux, B. Molecular dynamics study of calbindin D9k in the apo and singly and doubly calcium-loaded states (1998) Proteins 33, 265-284.
Summary: Describes molecular dynamics calculations on the apo, singly, and doubly calcium-laoded states of calbindin D9k, and relates the flucuations to experimental parameters of protein dynamics.
No information from this reference is currently stored in the database

Marchler-Bauer, A., Bryant, S.H A measure of success in fold recognition (1997) Trends Biochem Sci 22, 236-240.
No information from this reference is currently stored in the database

Marion, D., Ikura, M., Tschudin, R., Bax, A. Rapid recording of two-dimensional spectra without phase cycling. Application to the study of hydrogen exchange in proteins (1989) J Magn Reson 85, 393-399.
No information from this reference is currently stored in the database

Marsden, B.J, Shaw, G.S, Sykes, B.D Calcium binding proteins. Elucidating the contributions to calcium affinity from an analysis of species variants and peptide fragments (1990) Biochemistry Cell Biol 68, 587-601.
Summary: Contains useful sequence information on canonical EF hand binding loop. Uses an analysis of the frequency of residues at each position and the conserved nature of each position to ³derive² basic requirements for calcium binding..
No information from this reference is currently stored in the database

Marshak, D.R, Pesce, S.A, Stanley, L.C, Griffen, W.S Increased S100 beta neurotrophic activity in Alzheimer's disease temporal lobe (1992) Neurobiol Aging 13, 1-7.
View information in the CaBP database derived from this reference

Marston, S. Ca2+-dependent protein switches in actomyosin based contractile systems (1995) Int J Biochem Cell Biol 27, 97-108.
No information from this reference is currently stored in the database

Martin, A.CM., Orengo, C.A, Hutchinson, E.G, Jones, S. ., Karmirantzou, M. ., Laskowski, R.A, Mitchell, J.BM., Taroni, C. ., Thornton, J.M Protein folds and functions (1998) Structure 6, 875-884.
No information from this reference is currently stored in the database

Martin, S.R, Bayley, P.M The effects of Ca(2+) and Cd(2+) on the secondary and tertiary structure of bovine testis calmodulin (1986) Biochem J 238, 485-490.
No information from this reference is currently stored in the database

Martin, S.R, Bayley, P.M, Brown, S.E, Porumb, T., Zhang, M., Ikura, M. Spectoscopic characterization of a high-affinity calmodulin-target peptide hybrid molecule (1996) Biochemistry 35, 3508-3517.
No information from this reference is currently stored in the database

Martin, S.R, Linse, S., Johansson, C., Bayley, P.M, Forsen, S. Protein surface charges and Ca(2+) binding to individual sites in calbindin D9k: stopped flow studies (1990) Biochemistry 29, 4188-4193.
No information from this reference is currently stored in the database

Martindale, V., Salisbury, J. Phosphorylation of algal centrin is rapidly responsive to changes in the external milieu (1990) J Cell Sci 96, 395-402.
View information in the CaBP database derived from this reference

Mason, I.J, Murphy, D., Munke, M., Franke, U. Developmental and transformation-sensitive expression of the SPARC gene on mouse chromosome 11 (1986) EMBO J 5, 1831-1837.
View information in the CaBP database derived from this reference

Massom, L., Lee, H., Jarrett, H.W Trifluoperazine binding to porcine brain calmodulin and skeletal muscle troponin C (1990) Biochemistry 29, 671-681.
No information from this reference is currently stored in the database

Massom, L.R, Lukas, T.J, Persechini, A., Kretsinger, R.H, Watterson, D.M, Jarrett, H.W Trifluoperazine binding to mutant calmodulins (1991) Biochemistry 30, 663-667.
No information from this reference is currently stored in the database

Matsumura, H., Shiba, T., Inoue, T., Harada, S., Kai, Y. A novel mode of target recognition suggested by the 2.0 A structure of holo S100B from bovine brain (1998) Structure 6, 233-241.
Summary: The paper for PDB entry 1MHO..
View information in the CaBP database derived from this reference

Matsushima, N., Izumi, Y., Matsuo, T., Yoshino, H., Ueki, T., Miyake, Y. Binding of Ca(2+) and mastoparan to calmodulin induces a large change in the tertiary structure (1989) J Biochem 105, 883-887.
No information from this reference is currently stored in the database

Matsuura, I., Kimura, E., Tai, K., Yazawa, M. Mutagenesis of the fourth calcium-binding domain of yeast calmodulin (1993) J Biol Chem 268, 13267-13273.
No information from this reference is currently stored in the database

Maune, J.F, Klee, C.B, Beckingham, K. Ca2+-binding and conformational change in two series of point mutations to the individual Ca2+-binding sites of calmodulin (1992) J Biol Chem 267, 5286-5295.
No information from this reference is currently stored in the database

Maurer, P., Hohenester, E., Engel, J. Extracellular calcium-binding proteins (1996) Curr Opin Cell Biol 8, 609-617.
No information from this reference is currently stored in the database

May, A.CW., Johnson, M.S Improved genetic algorithm-based protein structure comparisons: pairwise and multiple superpositions (1995) Protein Eng 8, 873-882.
No information from this reference is currently stored in the database

McGary, C.T, Pan, Y.E, Michel, H. ., Guntrum, W.D, Neri, A. ., Welch, D.R Elevated expression of the neutrophil calcium-binding protein, MRP-14, in metastasis-enhancing neutrophils (1997) Anticancer Res 17, 1-6.
No information from this reference is currently stored in the database

McPhalen, C.A, Sielecki, A.R, Santarsiero, B.D, James, M.NG. Refined crystal structure of rat parvalbumin, a mammalia alpha-lineage parvalbumin, at 2.0 angstrom resolution (1994) J Mol Biol 235, 718-732.
View information in the CaBP database derived from this reference

McPhalen, C.A, Strynadka, N.CJ., James, M.NG. Calcium-binding sites in proteins: a structural perspective (1991) Adv Prot Chem 42, 77-144.
No information from this reference is currently stored in the database

Meador, W.E, Means, A.R, Quiocho, F. Modulation of calmodulin plasticity in molecular recognition on the basis of x-ray structures (1993) Science 262, 1718-1721.
View information in the CaBP database derived from this reference

Meador, W.E, Means, A.R, Quiocho, F.A Target enzyme recognition by calmodulin: 2.4 angstrom structure of a calmodulin-peptide complex (1992) Science 257, 1251-1255.
View information in the CaBP database derived from this reference

Means, A.R Calcium, calmodulin and cell cycle regulation (1994) FEBS Lett 347, 1-4.
Summary: A minireview summarizing the mechanisms by which calcium regulates the cell cycle. Focuses on biological aspects..
No information from this reference is currently stored in the database

Means, A.R, Klee, C.B Round table on Ca(2+)-binding proteins (1988) Adv Second Messenger Phosphoprotein Res 21, 181-187.
No information from this reference is currently stored in the database

Mellgren, R.L Calcium-dependent proteases: an enzyme system active at cellular membranes? (1987) FASEB J 1, 110-115.
Summary: Review of the possible roles of calpains in membrane fusion, memory storage and long-term potentiation, and the proteolytic activation of protein kinase C..
No information from this reference is currently stored in the database

Mercer, J.A, Seperack, P.K, Strobel, M.C, Copeland, N.G, Jenkins, N.A Novel myosin heavy chain encoded by murine dilute coat color locus (1991) Nature 349, 709-713.
No information from this reference is currently stored in the database

Meyer, D.F, Mabuchi, Y., Grabarek, Z. The role of Phe-92 in the Ca(2+)-induced conformational transition in the C-terminal domain of calmodulin (1996) J Biol Chem 271, 11284-11290.
Summary: Mutagensis-based study of the role of F92 in allowing the C-terminal domain to undergo the Ca2+-induced conformational change. .
View information in the CaBP database derived from this reference

Meyer, T., Stryer, L. Calcium spiking (1991) Annu Rev Biophys Biophys Chem 20, 153-174.
No information from this reference is currently stored in the database

Meyers, M.B "A 22 kDa calcium-binding protein, sorcin, is encoded by amplified genes in multidrug-resistant cells" in Novel Calcium Binding Proteins, (1991) Springer-Verlag, New York. 385-399.
No information from this reference is currently stored in the database

Middendorp, S., Paoletto, A., Schiebel, E., Bornens, M. Identification of a new mammalian centrin gene, more closely related to Saccharomyces cerevisiae CDC31 gene (1997) Proc Natl Acad Sci USA 94, 9141-9146.
Summary: Reports the discovery and preliminary analysis of a third isoform of human caltractin that is more similar to yeast CDC31, and laess similar to C. reihardtii caltractin, than are the other two isoforms.
View information in the CaBP database derived from this reference

Milan, D., Griffith, J., Su, M., Price, E.R, McKeon, F. The latch region of calcineurin B is involved in both immunosuppressant-immunophilin complex docking and phosphatase activation (1994) Cell 79, 437-447.
No information from this reference is currently stored in the database

Milligan, R.A Protein-protein interactions in the rigor actomyosin complex (1996) Proc Natl Acad Sci USA 93, 21-26.
No information from this reference is currently stored in the database

Millward, T.A, Heizmann, C.W, Schafer, B.W, Hemmings, B.A Calcium regulation of Ndr protein kinase mediated by S100 calcium-binding proteins (1998) EMBO J 17, 5913-5922.
No information from this reference is currently stored in the database

Milner, R.E, Famulski, K.S, Michalak, M. Calcium binding proteins in the sarcoplasmic/endoplasmic reticulum of muscle and nonmuscle cells (1992) Mol Cell Biochem 112, 1-13.
Summary: Review.
No information from this reference is currently stored in the database

Milos, M., Schaer, J.-J., Comte, M., Cox, J.A Calcium-proton and calcium-magnesium antagonisms in calmodulin: microcalorimetric and potentiometric analyses (1986) Biochemistry 25, 6279-6287.
No information from this reference is currently stored in the database

Minami, H. ., Tokumitsu, H. ., Mizutani, A. ., Watanabe, Y. ., Hidaka, H. . Specific binding of CAP-50 to calcyclin (1992) FEBS Lett 305, 217-219.
No information from this reference is currently stored in the database

Mizutani, A. ., Usada, N. ., Tokumitsu, H. ., Minami, H. ., Yasui, K. ., Kobayashi, R. ., Hidaka, H. . CAP-50, a newly identified annexin, localizes in nuclei of cultured fibroblast 3Y1 cells (1992) J Biol Chem 267, 13498-13504.
No information from this reference is currently stored in the database

Moeschler, H.J, Schaer, J.-J., Cox, J.A A thermodynamic analysis of the binding of calcium and magnesium ions to parvalbumin (1980) Eur J Biochem 111, 73-78.
View information in the CaBP database derived from this reference

Moews, P.C, Kretsinger, R.H Refinement of the structure of carp muscle calcium-binding parvalbumin by model building and difference fourier analysis (1975) J Mol Biol 91, 201-228.
No information from this reference is currently stored in the database

Montelione, G.T, Anderson, S. . Structural genomics: keystone for a human proteome project (1999) Nature Struct Biol 6, 11-12.
No information from this reference is currently stored in the database

Montelione, G.T, Lyons, B.A, Emerson, S.D, Tashiro, M. An efficient triple resonance experiment using carbon-13 isotropic mixing for determining sequence-specific resonance assignments of isotopically-enriched proteins (1992) J Am Chem Soc 114, 10974-10975.
No information from this reference is currently stored in the database

Montigiani, S., Neri, G., Neri, P., Neri, D. Alanine substitutions in calmodulin-binding peptides result in unexpected affinity enhancement (1996) J Mol Biol 258, 6-13.
No information from this reference is currently stored in the database

Moore, B. A soluble protein characteristic of the nervous system (1965) Biochem Biophys Res Comm 19, 739-744.
No information from this reference is currently stored in the database

Morii, K., Tanaka, R., Takahashi, Y., Minoshima, S., Fukuyama, R., Shimizu, N., Kuwano, R. Structure and chromosome assignment of human S100 alpha and beta subunit genes (1991) Biochem Biophys Res Comm 175, 185-191.
No information from this reference is currently stored in the database

Mukherjea, P. ., Maune, J.F, Beckingham, K. . Interlobe communication in multiple calcium-binding site mutants of Drosophila calmodulin (1996) Protein Sci 5, 468-477.
View information in the CaBP database derived from this reference

Mundlos, S., Schwann, B., Reichart, T., Zabel, B. Distribution of osteonectin mRNA and protein during human embryonic and fetal development (1992) J Histochem Cytochem 40, 238-291.
View information in the CaBP database derived from this reference

Munshi, H.G, Burks, D.J, Joyal, J.L, White, M.F, Sacks, D.B Ca(2+) regulates calmodulin binding to IQ motifs in IRS-1 (1996) Biochemistry 35, 15883-15889.
Summary: Demonstrates an interaction between CaM and IRS proteins. These proteins couple the insulin receptor to SH2 domain-containing proteins. The interaction is stronger in the presence of Ca2+ , but still observable in its absence. The authors postulate the involvement of puatative IQ motifs in the interaction of the IRS proteins with CaM..
No information from this reference is currently stored in the database

Muntener, M., Kaser, L., Weber, J., Berchtold, M.W Increase of skeletal muscle relaxation speed by direct injection of parvalbumin cDNA (1995) Proc Natl Acad Sci USA 92, 6504-6508.
View information in the CaBP database derived from this reference

Murachi, T. Calpain and calpastatin (1983) Trends Biochem Sci 8, 167-169.
Summary: A short review giving the basics about the calpain-calpastatin system.
No information from this reference is currently stored in the database

Murao, S., Collart, F.R, Huberman, E. A protein containing the cystic fibrosis antigen is an inhibitor of protein kinases (1989) J Biol Chem 264, 8356-8360.
View information in the CaBP database derived from this reference

Murphy, L.C, Murphy, L.J, Tsuyuki, D., Duckworth, M.L, Shiu, R.PC. Cloning and characterization of a cDNA encoding a highly conserved, putative calcium binding protein, identified by an anti-prolactin receptor antiserum (1988) J Biol Chem 263, 2397-2401.
View information in the CaBP database derived from this reference

Naka, M., Qing, Z.X, Sasaki, T., Tawara, I., Hamaguchi, S., Tanaka, T. Purification and characterization of a novel calcium-binding protein, S100C, from porcine heart (1994) Biochim Biophys Acta 1223, 348-353.
View information in the CaBP database derived from this reference

Nakashima, K., Maekawa, H., Yazawa, M. Chimeras of yeast and chicken calmodulin demonstrate differences in activation mechanisms of target enzymes (1996) Biochemistry 35, 5602-5610.
No information from this reference is currently stored in the database

Nakayama, S., Kretsinger, R.H Evolution of the EF-Hand family of proteins (1994) Annu Rev Biophys Biomol Struct 23, 473-507.
No information from this reference is currently stored in the database

Nakayama, S., Moncrief, N.D, Kretsinger, R.H Evolution of EF-hand calcium-modulated proteins. II. Domains of several subfamilies have diverse evolutionary histories (1992) J Mol Evol 34, 416-448.
No information from this reference is currently stored in the database

Nalefski, E.A, Falke, J.J The C2 domain calcium-binding motif: Structural and functional diversity (1996) Protein Sci 5, 2375-2390.
No information from this reference is currently stored in the database

Nelson, M.R, Chazin, W.J "Calmodulin as a calcium sensor" in , (1998) , . .
No information from this reference is currently stored in the database

Nelson, M.R, Chazin, W.J An interaction-based analysis of calcium-induced conformational changes in Ca2+ sensor proteins (1998) Protein Sci 7, 270-282.
View information in the CaBP database derived from this reference

Nicotera, P., Bellomo, G., Orrenius, S. Calcium-mediated mechanisms in chemically induced cell death (1992) Annu Rev Pharmacol Toxicol 32, 449-4470.
No information from this reference is currently stored in the database

Niki, I., Yokokura, Y., Sud, T., Kato, M., Hidaka, H. Ca2+ signaling and intracellular Ca2+ binding proteins (1996) J Biochem 120, 685-698.
No information from this reference is currently stored in the database

Nishimura, T., Goll, D.E Binding of calpain fragments to calpastatin (1991) J Biol Chem 266, 11842-11850.
No information from this reference is currently stored in the database

Novack, J.P, Charbonneau, H., Bentley, J.K, Walsh, K.A, Beavo, J.A Sequence comparison of the 63-,61-, and 59-kDa calmodulin-dependent cyclic nucleotide phosphodiesterases (1991) Biochemistry 30, 7940-7947.
No information from this reference is currently stored in the database

O'Keefe, S.J, Tamura, J., Kincaid, R.L, Tocci, M.J, O'Neill, E.A FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin (1992) Nature 357, 692-694.
No information from this reference is currently stored in the database

O'Neil, K.T, DeGrado, W.F How calmodulin binds its targets: sequence independent recognition of amphiphilic alpha-helices (1990) Trends Biochem Sci 15, 59-64.
Summary: Review summarizing knowledge on how calmodulin recognizes such a wide range of targets. Includes a discussion of the possible role of methionine residues.
No information from this reference is currently stored in the database

O'Neil, K.T, Erickson-Viitanen, S., DeGrado, W.F Photolabeling of calmodulin with basic, amphiphilic alpha-helical peptides containing p-benzoylphenylalanine (1989) J Biol Chem 264, 14571-14578.
No information from this reference is currently stored in the database

Ogawa, Y., Tanokura, M. Kinetic studies of calcium binding to parvalbumin from bullfrog skeletal muscle (1986) J Biochem 99, 81-89.
No information from this reference is currently stored in the database

Ogawa, Y., Tanokura, M. Steady-state properties of calcium binding to parvalbumins from bullfrog skeletal muscle: effects of Mg(2+), pH, ionic strength, and temperature (1986) J Biochem 99, 73-80.
No information from this reference is currently stored in the database

Ohki, S., Tsuda, S., Joko, S., Yazawa, M., Yagi, K., Hikichi, K. (1)H NMR study of amide proton exchange of calmodulin-mastoparan complex (1991) J Biochem 109, 234-237.
No information from this reference is currently stored in the database

Ohno, S., Minoshima, S., Kudoh, J., Fukuyama, R., Shimuzu, Y., Ohmi-Imajoh, S., Shimuzu, N., Suzuki, K. Four genes for the calpain family on four distinct human chromosomes (1990) Cytogenet Cell Genet 53, 225-229.
View information in the CaBP database derived from this reference

Ohta, H., Sasaki, T., Naka, M., Hiraoka, O., Miyamoto, C., Furuichi, Y., Tanaka, T. Molecular cloning and expression of the cDNA coding for a new member of the S100 protein family from porcine cardiac muscle (1991) FEBS Lett 295, 93-96.
View information in the CaBP database derived from this reference

Ohya, Y., Anraku, Y. A galactose-dependent cmd1 mutant of Saccharomyces cerevisiae: involvement of calmodulin in nuclear division (1989) Curr Genet 15, 113-120.
View information in the CaBP database derived from this reference

Ohya, Y., Botstein, D. Diverse essential functions revealed by complementing yeast calmodulin mutants (1994) Science 263, 963-966.
Summary: All phenylalanines in yeast calmodulin were mutated, singly and in multiples, and mutants were classified into complementation groups. Four such groups were identified..
No information from this reference is currently stored in the database

Ohya, Y., Botstein, D. Structure-based systematic isolation of conditional-lethal mutations in the single yeast calmodulin gene (1994) Genetics 138, 1041-154.
Summary: A very interesting paper detailing the effects of several single and multiple Phe to Ala calmodulin mutants on yeast viability.
View information in the CaBP database derived from this reference

Okano, H., Cyert, M.S, Ohya, Y. Importance of phenylalanine residues of yeast calmodulin for target binding and activation (1998) J Biol Chem 273, 26375-26382.
View information in the CaBP database derived from this reference

Okazaki, K., Niki, I., Iino, S., Kobayashi, S., Hidaka, H. A role of calcyclin, a Ca2+-binding protein, on the Ca2+-dependent insulin release from the pancreatic beta cell (1994) J Biol Chem 269, 6149-6152.
View information in the CaBP database derived from this reference

Otting, G., Liepinsh, E., Farmer, B.JN., III., Wuthrich, K. Protein hydration in aqueous solution (1991) Science 254, 974-980.
No information from this reference is currently stored in the database

Otting, G., Liepinsh, E., Farmer, B.JN., III., Wuthrich, K. Protein hydration studied with homonuclear 3D 1H NMR experiments. (1991) J Biomol NMR 1, 209-215.
No information from this reference is currently stored in the database

Padilla, A., Cave, A., Parello, J. Two-dimensional 1H nuclear magnetic resonance study of pike pI 5.0 parvalbumin (Esox lucius). Sequential resonance assignments and folding of the polypeptide chain (1998) J Mol Biol 204, 995-1017.
Summary: The reference for pdb entry 1PVA.
View information in the CaBP database derived from this reference

Palmer, A.GN., III., Rance, M., Wright, P.E Intramolecular motions of a zinc finger DNA-binding domain from Xfin characterized by proton-detected natural abundance 13C heteronuclear NMR spectroscopy (1991) J Am Chem Soc 113, 4371-4380.
No information from this reference is currently stored in the database

Panzer, S., Cooley, L., Miller, P.L Using explicity represented biological relationships for database navigation and searching via the world-wide web (1997) CABIOS 13, 281-290.
Summary: Describes a relational database with a web interface that contains information about cytoskeletal proteins and the relationships among these proteins. Relationships are stored as database entitites.
No information from this reference is currently stored in the database

Parmentier, M., Passage, E., Vassart, G., Mattei, M.G The human calbindin D28k (CALB1) and calretinin genes are located at 8q21.3->q22.1 and 16q22->q23, respectively, suggesting a common duplication with the carbonic anhydrase loci (1991) Cytogenet Cell Genet 57, 41-43.
View information in the CaBP database derived from this reference

Parmyakov, E.A, Medvedkin, V.N, Mitin, Y.V, Kretsinger, R.H Noncovalent complex between domain AB and domains CD*EF of parvalbumin (1991) Biochim Biophys Acta 1076, 67-70.
Summary: Removal of the non-functional EF-hand domain AB drastically reduces the calcium affinity of the remaining two EF-hands. Most of this lost affinity can be restored by adding the AB fragment back to the CD*EF fragment..
No information from this reference is currently stored in the database

Pascarella, S. ., Persio, R.D, Bossa, F. ., Argos, P. . Easy method to predict solvent accessibility from multiple protein sequence alignments (1998) Proteins 32, 190-199.
No information from this reference is currently stored in the database

Pauls, T.L, Cox, J.A, Berchtold, M.W The Ca(2+)-binding proteins parvalbumin and oncomodulin and their genes: new structural and functional findings (1996) Biochim Biophys Acta 1306, 39-54.
Summary: Excellent review of the current knowledge about the function, structure, and properties of parvalbumin.
View information in the CaBP database derived from this reference

Pauls, T.L, Durussel, I., Clark, I.D, Szabo, A.G, Berchtold, M.W, Cox, J.A Site-specific replacement of amino acid residues in the CD site of rat parvalbumin changes the metal specificity of this Ca2+/Mg2+-mixed site toward a Ca2+-specific site (1996) Eur J Biochem 242, 249-255.
No information from this reference is currently stored in the database

Payne, M.E, Fong, Y.-L., Ono, T., Colbran, R.J, Kemp, B.E, Soderling, T.R, Means, A.R Calcium/calmodulin-dependent protein kinase II: characterization of distinct calmodulin binding and inhibitory domains (1988) J Biol Chem 263, 7190-7195.
View information in the CaBP database derived from this reference

Pearce, S.HS., Brown, E.M The genetic basis of endocrine disease: disorders of calcium ion sensing (1996) J Clin Endrocin Metab 81, 2030-2035.
No information from this reference is currently stored in the database

Pearlstone, J.R, McCubbin, W.D, Kay, C.M, Sykes, B.D, Smilie, L.B Spectroscopic analysis of a methionine-48 to tyrosine mutant of chicken troponin C (1992) Biochemistry 31, 9703-9708.
No information from this reference is currently stored in the database

Pechere, J.-F., Derancourt, J., Haiech, J. The participation of parvalbumins in the activation-relaxation cycle of vertebrate fast skeletal muscle (1977) FEBS Lett 75, 111-114.
No information from this reference is currently stored in the database

Pedrocchi, M., Schafer, B.W, Durussel, I., Cox, J.A, Heizmann, C.W Purification and characterization of the recombinant human calcium-binding S100 proteins CAPL and CACY (1994) Biochemistry 33, 6732-6738.
View information in the CaBP database derived from this reference

Peersen, O.B, Madsen, T.S, Falke, J.J Intermolecular tuning of calmodulin by target peptides and proteins: Differential effects on ca2+ binding and implications for kinase activation (1997) Protein Sci 6, 794-807.
No information from this reference is currently stored in the database

Perret, C., Lomri, N., Gouhier, N., Auffray, C., Thomasset, M. The rat vitamin D-dependent calcium-binding protein (9-kDa CaBP) gene. Complete nucleotide sequence and structural organization (1988) Eur J Biochem 172, 43-51.
View information in the CaBP database derived from this reference

Persechini, A., Gansz, K.J, Paresi, R.J A role in enzyme activation for the N-terminal leader sequence in calmodulin (1996) J Biol Chem 271, 19279-19282.
Summary: This paper demonstrates that the n-terminal leader sequence before the first helix of CaM is absolutely required to activate skMLCK. Further mutagenesis studies showed that the tripeptide EEQ (residues 6-8) is responsible for this behavior.
View information in the CaBP database derived from this reference

Persechini, A., Gansz, K.J, Paresi, R.J Activation of myosin light chain kinase and nitric oxide synthase activities by engineered calmodulins with duplicated or exchanged EF hand pairs (1996) Biochemistry 35, 224-228.
No information from this reference is currently stored in the database

Persechini, A., Kretsinger, R.H The central helix of calmodulin functions as a flexible tether (1988) J Biol Chem 263, 12175-12178.
No information from this reference is currently stored in the database

Persechini, A., McMillan, K., Leakey, P. Activation of myosin light chain kinase and nitric oxide synthase activities by calmodulin fragments (1994) J Biol Chem 269, 16148-16514.
No information from this reference is currently stored in the database

Persechini, A., Stemmer, P.M, Ohashi, I. Localization of unique functional determinants in the calmodulin lobes to individual EF hands (1996) J Biol Chem 271, 32217-32225.
No information from this reference is currently stored in the database

Pohl, V., Van Ramplebergh, J., Mellaert, S., Pochet, R. Calretinin in rat ovary: An in situ hybridization and immunohistochemical study (1992) >Biochim Biophys Acta 1160, 87-94.
View information in the CaBP database derived from this reference

Polans, A., Palczewski, K., Asson-Batres, M.-A., Ohguro, H., Witkowska, D., Haley, T., Baizer, L., Crabb, J. Purification and primary structure of Capl, an S-100-related calcium binding protein isolated from bovine retina (1993) J Biol Chem 269, 6233-6240.
View information in the CaBP database derived from this reference

Potts, B., Smith, J., Akke, M., Macke, T., Okazaki, K., Hidaka, H., Case, D., Chazin, W. The structure of calcyclin reveals a novel homodimeric fold for S100 Ca(2+)-binding proteins (1995) Nat Struct Biol 2, 790-796.
View information in the CaBP database derived from this reference

Potts, B.C, Chazin, W.J Chemical shift homology in proteins (1998) J Biomolec NMR 11, 45-57.
No information from this reference is currently stored in the database

Potts, B.CM., Carlstrom, G., Okazaki, K., Hidaka, H., Chazin, W.J (1)H NMR assignments of apo and comparative structural analysis with calbindin D9k and S100b (1996) Protein Sci 5, 2162-2174.
No information from this reference is currently stored in the database

Precheur, B., Munier, H., Mispelter, J., Barzu, O., Craescu, C. (1)H and (15)N characterization of free and bound states if an amphiphilic peptide interacting with calmodulin (1992) Biochemistry 31, 229-236.
No information from this reference is currently stored in the database

Prechur, B., Cox, J.A, Petrova, T., Mispelter, J., Craescu, C.T Nereis sarcoplasmic Ca2+-binding protein has a highly unstructured apo state which is switched to the native state upon binding of the first Ca2+ ion (1996) FEBS Lett 395, 89-94.
No information from this reference is currently stored in the database

Putkey, J.A "Troponin C" in Guidebook to the Calcium-Binding Proteins, M.R.Celio, T.Pauls, B.Schwaller, eds. (1996) Oxford University Press, Oxford. 175-178.
No information from this reference is currently stored in the database

Putkey, J.A, Ono, T., VanBerkum, M.FA., Means, A.R Functional significance of the central helix in calmodulin (1988) J Biol Chem 263, 11242-11249.
No information from this reference is currently stored in the database

Putkey, J.A, Sweeney, H.L, Campbell, S.T Site-directed mutation of the trigger calcium-binding sites in cardiac troponin C (1989) J Biol Chem 264, 12370-12378.
No information from this reference is currently stored in the database

Raghunathan, S., Chandross, R.J, Cheng, B.-P., Persechini, A., Sobottka, S.E, Kretsinger, R.H The linker of des-Glu(84)-calmodulin is bent (1993) Proc Natl Acad Sci USA 90, 6869-6873.
No information from this reference is currently stored in the database

Rammes, A. ., Roth, J. ., Goebeler, M. ., Klempt, M. ., Hartmann, M. ., Sorg, C. . Myeloid-related protein (MRP) 8 and MRP14, calcium-binding proteins of the S100 family, are secreted by activated monocytes via a novel, tubulin-dependent pathway (1997) J Biol Chem 272, 9496-9502.
No information from this reference is currently stored in the database

Rao, S.T, Satyshur, K.A, Greaser, M.L, Sundaralingam, M. X-ray structures of Mn, Cd, and Tb metal complexes of troponin C (1996) Acta Crystall D 52, 916-922.
View information in the CaBP database derived from this reference

Rao, S.T, Wu, S., Satyshur, K.A, Ling, K.Y, Kung, C., Sundaralingam, M. Structure of Paramecium tetraurella calmodulin at 1.8 angstrom resolution (1993) Protein Sci 2, 436-447.
No information from this reference is currently stored in the database

Rasmussen, H. The cycling of calcium as an intracellular messenger. (1989) Sci Am , 66-73.
No information from this reference is currently stored in the database

Rasmussen, H. The calcium messenger system (first of two parts) (1986) New Eng Journ Med 314, 1094-1101.
No information from this reference is currently stored in the database

Rasmussen, H. The calcium messenger system (second of two parts) (1986) New Eng Journ Med 314, 1164-1170.
No information from this reference is currently stored in the database

Rayment, I., Holden, H.M, Whittaker, M., Yohn, C.B, Lorenz, M., Holmes, K.C, Milligan, R.A Structure of the actin-myosin complex and its implications for muscle contraction (1993) Science 261, 58-65.
No information from this reference is currently stored in the database

Rayment, I., Rypniewski, W.R, Schmidt-Base, K., Smith, R., Tomchick, D.R, Benning, M.M, Winkelmann, D.A, Wesenberg, G., Holden, H.M Three-dimensional structure of myosin subfragment-1: A molecular motor (1993) Science 261, 50-58.
View information in the CaBP database derived from this reference

Rebhan, M. ., Chalifa-Caspi, V. ., Prilusky, J. ., Lancet, D. . GeneCards: integrating information about genes, proteins and diseases (1997) Trends Genet 13, 163.
No information from this reference is currently stored in the database

Reddy, B.VR., Datta, S. ., Tiwari, S. . Use of propensities of amino acids to the local structural environments to understand effect of substitution mutations on protein stability (1998) Protein Eng 11, 1137-1145.
No information from this reference is currently stored in the database

Ren, K., Ruda, M.A A comparative study of the calcium-binding proteins calbindin D28k, calretinin, calmodulin and parvalbumin in the rat spinal cord (1994) Brain Res Rev 19, 163-179.
No information from this reference is currently stored in the database

Resibois, A., Rogers, J.H Calretinin in the rat brain: An immunohistochemical study (1992) Neuroscience 46, 101-134.
Summary: A very thorough examination of the localization of calretinin in rat brains.
View information in the CaBP database derived from this reference

Rety, S. ., Sopkova, J. ., Renouard, M. ., Osterloh, D. ., Gerke, V. ., Tabaries, S. ., Russo-Marie, F. ., Lewit-Bentley, A. . The crystal structure of p11 with the annexin II N-terminal peptide (1999) Nature Struct Biol 6, 89-95.
No information from this reference is currently stored in the database

Rety, S., Sopkova, J., Renouard, M., Osterloh, D., Gerke, V., Tabaries, S., Russo-Marie, F., Lewit-Bentley, A. The crystal structure of a complex of p11 with the annexin-II N-terminal peptide (1999) Nat Struct Biol 6, 89-95.
Summary: .
View information in the CaBP database derived from this reference

Rhyner, J.A, Koller, M., Durussel-Gerber, I., Cox, J.A, Strehler, E.E Characterization of human calmodulin-like protein expressed in Escherichia coli (1992) Biochemistry 31, 12826-12832.
View information in the CaBP database derived from this reference

Richardson, J.S, Richardson, D.C Helix lap-joints as ion-binding sites: DNA-binding motifs and Ca-binding "EF Hands" are related by charge and sequence reversal (1988) Proteins 4, 229-239.
No information from this reference is currently stored in the database

Ritzler, J.M, Sawhney, R., Gerts-van-Kessel, A.H, Grzeschik, K.H, Schinzel, A., Berchtold, M.W The genes for the highly homologous Ca2+-binding proteins oncomodulin and parvalbumin are not linked on the human genome (1992) Genomics 12, 567-572.
View information in the CaBP database derived from this reference

Roberts, D.M Protein kinases with calmodulin-like domains: novel targets of calcium signals in plants (1993) Curr Opin Cell Biol 5, 242-246.
Summary: A concise introduction to calcium-dependent protein kinases in plants.
View information in the CaBP database derived from this reference

Roberts, D.M, Harmon, A.C Calcium-modulated proteins: targets of intracellular calcium signals in higher plants (1992) Annu Rev Plant Mol Biol 43, 375-414.
View information in the CaBP database derived from this reference

Rogers, M.S, Strehler, E.E "Calmodulin" in Guidebook to the Calcium-Binding Proteins, M.R.Celio, T.Pauls, B.Schwaller, eds. (1996) Oxford University Press, Oxford. 34-40.
Summary: A brief chapter summarizing the basic characteristics and properties of calmodulin.
View information in the CaBP database derived from this reference

Rogers, M.S, Strehler, E.E "Calmodulin-like proteins" in Guidebook to the Calcium-Binding Proteins, M.R.Celio, T.Pauls, B.Schwaller, eds. (1996) Oxford University Press, Oxford. 41-43.
Summary: A brief chapter summarizing the basic properties and characteristics of calmodulin-like proteins.
View information in the CaBP database derived from this reference

Roquet, F., Declercq, J.-P., Tinant, B., Rambaud, J., Parello, J. Crystal structure of the unique parvalbumin component from muscle of the leopard shark (Triakis semifasciata): The first X-ray study of an alpha-parvalbumin (1992) J Mol Biol 223, 705-720.
Summary: This is the reference for pdb entry 5PAL.
View information in the CaBP database derived from this reference

Rose, G.D, Geselowitz, A.R, Lesser, G.J, Lee, R.H, Zehfus, M.H Hydrophobicity of amino acid residues in globular proteins (1985) Science 229, 834-838.
No information from this reference is currently stored in the database

Roth, J. ., Teigelkamp, S. ., Wilke, M. ., Grun, L. ., Tummler, B. ., Sorg, C. . Complex pattern of the myelo-monocytic differentiation antigens MRP8 and MRP14 during chronic airway inflammation (1992) Immunobiology 3-4, 304-314.
No information from this reference is currently stored in the database

Russell, R.B, Saqi, M.AS., Sayle, R.A, Bates, P.A, Sternberg, M.JE. Recognition of analagous and homologous protein folds: Analysis of sequence and structure conservation (1997) J Mol Biol 269, 423-439.
No information from this reference is currently stored in the database

Rustandi, R.R, Drohat, A.C, Baldisseri, D.M, Wilder, P.T, Weber, D.J The Ca2+-dependent interaction of S100B(bb) with a peptide derived from p53 (1998) Biochemistry 37, 1951-1960.
Summary: A report of the calcium-dependent interaction of S100B with a peptide derived fromt he tumor suppressor p53. NMR results imply that this peptide interacts with the hinge and the C-terminus of the S100B subunits..
View information in the CaBP database derived from this reference

Sacks, D.B, Mazus, B., Joyal, J.L The activity of calmodulin is altered by phosphorylation: modulation of calmodulin function by the site of phosphate incorporation. (1995) Biochem J 312, 197-204.
View information in the CaBP database derived from this reference

Sacks, D.B, McDonald, J.M Insulin-stimulated phosphorylation of calmodulin by rat liver insulin receptor preparations (1988) J Biol Chem 263, 2377-2383.
View information in the CaBP database derived from this reference

Saitoh, S., Takamatsu, K., Kobayashi, M., Noguchi, T. Distribution of hippocalcin mRNA and immunoreactivity in rat brain (1993) Neurosci Lett 157, 107-110.
View information in the CaBP database derived from this reference

Salemme, F.R, Spurlino, J., Bone, R. Serendipity meets precision: the integration of structure-based drug design and combinatorial chemistry for efficient drug discovery (1997) Structure 5, 319-324.
No information from this reference is currently stored in the database

Sali, A., Blundell, T.L Comparative protein modelling by satisfaction of spatial restraints (1993) J Mol Biol 234, 779-815.
Summary: Article describing the method of protein modelling used by MODELLER.
No information from this reference is currently stored in the database

Salisbury, J.L Centrin, centrosomes, and mitotic spindle poles (1995) Curr Opin Cell Biol 7, 39-45.
No information from this reference is currently stored in the database

Saris, C.JM., Kristensen, T., D'Eustachio, P., Hicks, L.J, Noonan, D.J, Hunter, T., Tack, B.F cDNA sequence and tissue distribution of the mRNA for bovine and murine p11, the S100-related light chain of the protein-tyrosine kinase substrate p36 (1987) J Biol Chem 262, 10663-10671.
View information in the CaBP database derived from this reference

Sastry, M., Ketchem, R.R, Crescenzi, O., Weber, C., Lubienski, M.J, Hidaka, H., Chazin, W.J The three-dimensional structure of Ca2+-bound calcyclin: implications for Ca2+-signal transduction by S100 proteins (1998) Structure 6, 223-231.
View information in the CaBP database derived from this reference

Satyshur, K., Rao, S., Pyzalska, D., Drendel, W., Greaser, M., Sundraralingam, M. Refined structure of chicken skeletal muscle troponin C in the two-calcium state at 2 angstrom resolution (1988) J Biol Chem 263, 1628-1647.
View information in the CaBP database derived from this reference

Satyshur, K.A, Pyzalska, D., Greaser, M., Rao, S.T, Sundaralingam, M. Structure of chicken skeletal muscle troponin C at 1.78 A resolution (1994) Acta Crystall D 50, 40-49.
No information from this reference is currently stored in the database

Schafer, B. "S100A2" in Guidebook to the Calcium-Binding Proteins, M.R.Celio, T.Pauls, B.Schwaller, eds. (1996) Oxford University Press, Oxford. 137.
Summary: A brief chapter summarizing the basic characteristics and properties of S100A2.
View information in the CaBP database derived from this reference

Schafer, B. "S100A3" in Guidebook to the Calcium-Binding Proteins, M.R.Celio, T.Pauls, B.Schwaller, eds. (1996) Oxford University Press, Oxford. 138-139.
Summary: A brief chapter summarizing the basic characteristics and properties of S100A3.
View information in the CaBP database derived from this reference

Schafer, B.W "S100A5" in Guidebook to the Calcium-Binding Proteins, M.R.Celio, T.Pauls, B.Schwaller, eds. (1996) Oxford University Press, Oxford. 141-142.
Summary: A brief chapter summarizing the basic characteristics and properties of S100A5.
View information in the CaBP database derived from this reference

Schafer, B.W, Heizmann, C.W The S100 family of EF-hand calcium-binding proteins: functions and pathology (1996) Trends Biochem Sci 21, 134-140.
No information from this reference is currently stored in the database

Schafer, B.W, Wicki, R., Engelkamp, D., Mattei, J.-G., Heizmann, C.W Isolation of a YAC clone covering a cluster of nine S100 genes on human chromosome 1q21: rationale for a new nomenclature for the S100 calcium-binding protein family (1995) Genomics 25, 638-643.
View information in the CaBP database derived from this reference

Schaller, G.E, Harmon, A.C, Sussman, M.R Characterization of a calcium- and lipid-dependent protein kinase associated with the plasma membrane of oat (1992) Biochemistry 31, 1721-1727.
No information from this reference is currently stored in the database

Schiebel, E., Bornens, M. In search of a function for centrins (1995) Trends Cell Biol 5, 197-201.
No information from this reference is currently stored in the database

Schwaller, B. "Calretinin" in Guidebook to the Calcium-Binding Proteins, M.R.Celio, T.Pauls, B.Schwaller, eds. (1996) Oxford University Press, Oxford. 26-28.
Summary: A brief chapter summarizing the basic characteristics and properties of calretinin.
View information in the CaBP database derived from this reference

Schwarzbauer, J., Spencer, C.S The Caenorhabditis elegans homolog of the extracellula calcium binding protein SPARC/osteonectin affects nematode body morphology and mobility (1993) Mol Biol Cell 4, 941-952.
View information in the CaBP database derived from this reference

Seamon, K.B, Kretsinger, R.H Calcium-modulated proteins. (1983) Met Ions Biol 6, 1-51.
No information from this reference is currently stored in the database

Seemann, J. ., Weber, K. ., Gerke, V. . Annexin I targets S100C to early endosomes (1997) FEBS Lett 413, 185-190.
No information from this reference is currently stored in the database

Seemann, J. ., Weber, K. ., Gerke, V. . Structural requirements for annexin I-S100C complex-formation. (1996) Biochem J 319, 123-129.
No information from this reference is currently stored in the database

Sekharudu, Y.C, Sundaralingam, M. A structure-function relationship for the calcium affinities of regulatory proteins containing 'EF-hand' pairs (1988) Protein Eng 2, 139-146.
Summary: The authors performed QSAR analysis on calmodulin, troponin C, and parvalbumin, and used this to infer the effect of ligands and hydrophobicity of other residues on calcium affinity.
No information from this reference is currently stored in the database

Sellers, J.A, Goodson, H.V Motor proteins 2: myosin (1995) Protein Profile 2, 1323-1423.
No information from this reference is currently stored in the database

Sellers, P., Laynez, J., Thulin, E., Forsen, S. Thermodynamics of Ca(2+) binding to calmodulin and its tryptic fragments (1991) Biophys J 39, 199-204.
No information from this reference is currently stored in the database

Senn, H., Werner, B., Messerle, B.A, Weber, C., Traber, R., Wuthrich, K. Stereospecific assignment of the methyl 1H NMR lines of valine and leucine in polypeptides by nonrandom 13C labelling. (1989) FEBS Lett 249, 113-118.
No information from this reference is currently stored in the database

Seto-Okshima, A., Lawson, D.EM., Emson, P.C, Mountjoy, C.Q, Carasco, L.H Loss of matrix calcium binding protein containing neurons in Huntington's disease (1988) Lancet 1, 1252-1255.
View information in the CaBP database derived from this reference

Shaw, G.S, Findlay, W.A, Semchuk, P.D, Hodges, R.S, Sykes, B.D Specific formation of a heterodimeric two-site calcium-binding domain from synthetic peptides (1992) J Am Chem Soc 114, 6258-6259.
No information from this reference is currently stored in the database

Shaw, G.S, Hodges, R.S, Sykes, B.D Calcium-induced peptide association to form an intact protein domain: (1)H NMR structural evidence (1990) Science 249, 280-283.
No information from this reference is currently stored in the database

Shaw, G.S, Hodges, R.S, Sykes, B.D Determination of the solution structure of a synthetic two-site calcium-binding homodimeric protein domain by NMR spectroscopy (1992) Biochemistry 31, 9572-9580.
Summary: The reference for pdb entry 1CTA.
View information in the CaBP database derived from this reference

Shaw, G.S, Sykes, B.D NMR solution structure of a synthetic troponin C heterodimeric domain (1996) Biochemistry 35, 7429-7438.
Summary: The reference for pdb entry 1PON.
View information in the CaBP database derived from this reference

Sheldon, A., Head, J.F Calcium-binding properties of two high affinity calcium-binding proteins from squid optic lobe (1988) J Biol Chem 263, 14384-14389.
View information in the CaBP database derived from this reference

Sia, S.K, Li, M.X, Spyracopoulos, L., Gagne, S.M, Liu, W., Putkey, J.A, Sykes, B.D Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain (1997) J Biol Chem 272, 18216-18221.
Summary: The reference for pdb entry 3CTN.
View information in the CaBP database derived from this reference

Siegenthaler, G. ., Roulin, K. ., Chatellard-Gruaz, D. ., Hotz, R. ., Saurat, J.H, Hellman, U. ., Hagens, G. . A heterocomplex formed by the calcium-binding proteins MRP8 (S100A8) and MRP14 (S100A9) binds unsaturated fatty acids with high affinity (1997) J Biol Chem 272, 9371-9377.
No information from this reference is currently stored in the database

Sjolin, L., Svensson, L.A, Prince, E., Sundrell, S. Phase improvement in the structure interpretation of fragment Tr2C from bull testis calmodulin using combined entropy maximization and solvent flattening (1990) Acta Crystall B 46, 209-215.
View information in the CaBP database derived from this reference

Skelton, N.J, Akke, M., Kordel, J., Thulin, E., Forsen, S., Chazin, W.J 15N NMR assignment and chemical shift analysis of uniformly labeled 15N calbindin D9k in the apo, (Cd2+)1 and (Ca2+)2 states. (1992) FEBS Lett 303, 136-140.
No information from this reference is currently stored in the database

Skelton, N.J, Forsen, S., Chazin, W.J (1)H NMR resonance assignments, secondary structure, and global fold of apo bovine calbindin (1990) Biochemistry 29, 5752-5761.
Summary: Sequence assignment and preliminary structural work on apo calbindin indicates that it has the same basic tertiary structure as the calcium-loaded state, but changed dynamics..
No information from this reference is currently stored in the database

Skelton, N.J, Kordel, J., Akke, M., Chazin, W.J Nuclear magnetic resonance studies of the internal dynamics in apo, (Cd(2+))1 and (Ca(2+))2 calbindin D9k (1992) J Mol Biol 227, 1100-1117.
No information from this reference is currently stored in the database

Skelton, N.J, Kordel, J., Akke, M., Forsen, S., Chazin, W.J Signal transduction versus beffering activity in Ca(2+)-binding Proteins (1994) Nat Struct Biol 1, 239-245.
Summary: Comparison of calbindin D9kıs response to binding calcium with the modeled response of calmodulin and troponin C (this model has since been supported by NMR structures of calmodulin and troponin C)..
No information from this reference is currently stored in the database

Skelton, N.J, Kordel, J., Chazin, W.J Determination of the solution structure of apo calbindin D9k by NMR spectroscopy (1995) J Mol Biol 249, 441-462.
View information in the CaBP database derived from this reference

Skelton, N.J, Palmer, A.GN., III., Akke, M., Kordel, J., Rance, M., Chazin, W.J Practical aspects of two-dimensional proton-detected 15N spin relaxation measurements (1993) J Magn Reson 102, 253-264.
No information from this reference is currently stored in the database

Slupsky, C.M, Sykes, B.D NMR solution structure of calcium-saturated skeletal muscle troponin C (1995) Biochemistry 34, 15953-15964.
Summary: The reference for pdb entry 1TNW.
View information in the CaBP database derived from this reference

Small, E.W, Anderson, S.R Fluorescence anisotropy decay demonstrates calcium-dependent shape changes in photo-cross-linked calmodulin (1988) Biochemistry 27, 419-428.
No information from this reference is currently stored in the database

Smith, L., Greenfield, N.J, Hitchcock-DeGregori, S.E The effects of deletion of the amino-terminal helic on troponin C function and stability (1994) J Biol Chem 269, 9857-9863.
No information from this reference is currently stored in the database

Smith, S.P, Shaw, G.S A novel calcium-sensitive switch revealed by the structure of human S100B in the calcium-bound form (1998) Structure 6, 211-222.
Summary: The paper for PDB entry 1UWO..
View information in the CaBP database derived from this reference

Smith, T.F Functional genomics- bioinformatics is ready for the challenge (1998) Trends Genet 14, 291-293.
No information from this reference is currently stored in the database

Sobue, K., Muramoto, Y., Fujita, M., Kakiuchi, S. Purification of a calmodulin-binding protein from chicken gizzard that interacts with F-actin (1981) Proc Natl Acad Sci USA 78, 5652-5653.
View information in the CaBP database derived from this reference

Sonnemann, J. ., Drugeon, G. ., Haenni, A.-, Mutzel, R. . Elongation in a Dictyostelium in vitro translation system is affected by calmodulin antagonists (1993) FEBS Lett 329, 183-188.
View information in the CaBP database derived from this reference

Sorace, J.M, Canfield, K. Collaborative bioinformatics: data warehouses for targeted experimental results (1998) J Interferon Cytokine Res 18, 799-802.
Summary: Describes a model for a relational database to store information about cytokine expression and regulation.
No information from this reference is currently stored in the database

Sorensen, B.R, Shea, M.A Interactions between domains of apo calmodulin alter calcium binding and stability (1998) Biochemistry 37, 4244-4253.
No information from this reference is currently stored in the database

Sorg, C. . The calcium binding proteins MRP8 and MRP14 in acute and chronic inflammation (1992) Behring Inst Mitt 91, 126-137.
No information from this reference is currently stored in the database

Soriano-Garcia, M., Padmanabhan, K., deVos, A.M, Tulinsky, A. The Ca2+ ion and membrane binding structure of the gla domain of Ca-prothrombin fragment 1 (1992) Biochemistry 31, 2554-2566.
No information from this reference is currently stored in the database

Spang, A., Courtney, I., Fackler, U., Matznar, M., Scheibel, E. The calcium-binding protein cell division cycle 31 of Saccharomyces cerevisiae is a component of the half bridge of the spindle pole body (1993) J Cell Biol 123, 405-416.
No information from this reference is currently stored in the database

Spera, S.I, Mitsuhiko, I., Bax, A. Measurement of the exchange rates of rapidly exchanging amide protons: Application to the study of calmodulin and its complex with a myosin light chain kinase fragment (1991) J Biomol NMR 1, 155-165.
No information from this reference is currently stored in the database

Spyracopoulos, L., Li, M.X, Sia, S.K, Gagne, S.M, Chandra, M., Solaro, R.J, Sykes, B.D Calcium-induced structural transition in the regulatory domain of human cardiac troponin C (1997) Biochemistry 36, 12138-12146.
View information in the CaBP database derived from this reference

Starovasnik, M.A, Su, D.-R., Beckingham, K., Klevit, R.E A series of point mutations reveal interactions between calcium-binding sites of calmodulin (1992) Protein Sci 1, 245-253.
No information from this reference is currently stored in the database

Staubli, F., Klein, A., Rentsch, J.M, Berchtold, M.W Structure and chromosomal localization of the mouse oncomodulin gene (1995) Mammal Genome 6, 769-777.
View information in the CaBP database derived from this reference

Steiner, J.P, Walke, H.TN., Jr., Bennet, V. Calcium/calmodulin inhibits direct binding of spectrin to synaptosomal membranes (1989) J Biol Chem 264, 2783-2791.
No information from this reference is currently stored in the database

Strauss, K.I, Issacs, K.R, Ha, Q.N, Jacobwitz, D.M Calretinin is expressed in the Leydig cells of rat testis (1994) >Biochim Biophys Acta 1219, 435-440.
View information in the CaBP database derived from this reference

Stromqvist, M., Berglund, A., Shanbhag, V.P, Backman, L. Influence of calmodulin on the human red cell membrane skeleton (1988) Biochemistry 27, 1104-1110.
No information from this reference is currently stored in the database

Strynadka, N.CJ., Cherney, M., Sielecki, A.R, Li, M.X, Smillie, L.B, James, M.NG. Structural details of a calcium-induced molecular switch: X-ray crystallographic analysis of the calcium-saturated N-terminal domain of troponin C at 1.75 A resolution (1997) J Mol Biol 273, 238-255.
Summary: Presents the crystal structure of calcium-loaded troponin C N domain, and compares it to the apo TnC-N domain fromt he earlier crystal structure. Based on these structures, the authors present an interesting hypothesis about the mechanism of calcium-induced opening.
View information in the CaBP database derived from this reference

Strynadka, N.CJ., James, M.NG. Crystal structures of the helix-loop-helix calcium-binding proteins (1989) Annu Rev Biochemistry 58, 951-998.
Summary: A somewhat outdated, but still useful, review of the crystal structures of calmodulin, troponin C, calbindin D9k and parvalbumin. Includes a useful discussion on the preferred conformation of residues in the binding loop, derived from the structural information available at the time..
No information from this reference is currently stored in the database

Strynadka, N.CJ., James, M.NG. Towards an understanding of the effects of calcium on protein structure and function (1991) Curr Opin Struct Biol 1, 905-914.
No information from this reference is currently stored in the database

Su, Z. ., Fan, D. ., George, S.E Role of domain 3 of calmodulin in activation of calmodulin-stimulated phosphodiesterase and smooth muscle myosin light chain kinase (1994) J Biol Chem 269, 16761-16765.
No information from this reference is currently stored in the database

Subramaniam, S. The biology workbench-- a seamless database and analysis environment for the biologist (1998) Proteins 32, 1-2.
No information from this reference is currently stored in the database

Sutoo, D., Akiyama, K., Fujii, N., Matsushita, K. (1)H-NMR studies of calmodulin: the effect of W-7 (N-(6-aminohexyl)-5-chloro-1-napthalenesulfonamide) and Ca(2+) on conformational changes of calmodulin (1986) Biochim Biophys Acta 873, 156-160.
No information from this reference is currently stored in the database

Suttie, J.W Synthesis of vitamin K-dependent proteins (1993) FASEB J 7, 445-452.
No information from this reference is currently stored in the database

Svensson, B., Jonsson, B., Woodward, C. Electrostatic contributions to the binding of Ca(2+) in calbindin mutants: A Monte Carlo study (1990) Biophys J 38, 179-183.
No information from this reference is currently stored in the database

Svensson, B., Jonsson, B., Woodward, C.E, Linse, S. Ion-binding properties of calbindin D9k: a Monte Carlo simulation study (1991) Biochemistry 30, 5209-5217.
No information from this reference is currently stored in the database

Svensson, L.A, Thulin, E., Forsen, S. Proline cis-trans isomers in calbindin D9k observed by x-ray crystallography (1992) J Mol Biol 223, 601-606.
View information in the CaBP database derived from this reference

Swain, A.L, Kretsinger, R.H, Amma, E.L Restrained least squares refinement of native (calcium) and cadmium-substituted carp parvalbumin using x-ray crystallographic data at 1.6-angstrom resolution (1989) J Biol Chem 264, 16620-16628.
View information in the CaBP database derived from this reference

Swanljung-Collins, H., Collins, J.H Ca(2+) stimulates the Mg(2+)-ATPase activity of brush border myosin I with three or four calmodulin light chains but inhibits with less than two bound (1991) J Biol Chem 266, 1312-1319.
View information in the CaBP database derived from this reference

Swaroop, A., Hogan, B.LM., Franke, U. Molecular analysis of the cDNA for human SPARC/osteonectin/BM-40: sequence, expression, and localization of the gene to chromosome 5q31-q33 (1988) Genomics 2, 37-47.
View information in the CaBP database derived from this reference

Swindells, M.B, Ikura, M. Pre-formation of the semi-open conformation by the apo-calmodulin C-terminal domain and implications for binding IQ motifs (1996) Nat Struct Biol 3, 501-504.
No information from this reference is currently stored in the database

Szczesna, D., Guzman, G., Miller, T., Zhao, J., Farokhi, K., Ellemberger, H., Potter, J.D The role of the four Ca2+ binding sites of troponin C in the regulation of skeletal muscle contraction (1996) J Biol Chem 271, 8381-8386.
No information from this reference is currently stored in the database

Szebenyi, D.ME., Moffat, K. The refined structure of vitamin D-dependent calcium-binding protein from bovine intestine (1986) J Biol Chem 261, 8761-8777.
No information from this reference is currently stored in the database

Szebenyi, D.ME., Obendorf, S.K, Moffat, K. Structure of vitamin D-dependent calcium-binding protein from bovine intestine (1981) Nature 294, 327-332.
View information in the CaBP database derived from this reference

Szent-Gyorgyi, A.G, Szentkiraly, E.M, Kendrick-Jones, J. The light chains of scallop myosin as regulatory subunits (1973) J Mol Biol 74, 179-203.
No information from this reference is currently stored in the database

Tabernero, L., Taylor, D.A, Chandross, R.J, VanBerkum, M.FA., Means, A.R, Quiocho, F.A, Sack, J.S The structure of a calmodulin mutant with a deletion in the central helix: implications for molecular recognition and protein binding (1997) Structure 5, 613-622.
View information in the CaBP database derived from this reference

Taillon, B.E, Adler, S.A, Suhan, J.P, Jarvik, J.W Mutational analysis of centrin: An EF-hand protein associated with three distinct contractile fibers in the basal body apparatus of Chlamydomonas (1992) J Cell Biol 119, 1613-1624.
No information from this reference is currently stored in the database

Takagi, T., Cox, J.A Amino acid sequences of four isoforms of amphioxus sarcoplasmic calcium-binding proteins (1990) Eur J Biochem 192, 387-399.
No information from this reference is currently stored in the database

Takagi, T., Konishi, K., Cox, J.A Amino acid sequence of two sarcoplasmic calcium-binding proteins from the protochordate Amphioxus (1986) Biochemistry 25, 3585-3592.
No information from this reference is currently stored in the database

Takagi, T., Valette-Talbi, L., Cox, J.A Primary structure of three minor isoforms of amphioxous sarcoplasmic calcium-binding proteins (1992) FEBS Lett 302, 159-160.
No information from this reference is currently stored in the database

Takamatsu, K., Kobayashi, M., Saitoh, S., Fujishiro, M. Molecular cloning of human hippocalcin cDNA and chromosomal mapping of its gene (1994) Biochem Biophys Res Comm 200, 606-611.
View information in the CaBP database derived from this reference

Takamatsu, K., Saitoh, S., Kobayashi, M. "Hippocalcin" in Guidebook to the Calcium-Binding Proteins, M.R.Celio, T.Pauls, B.Schwaller, eds. (1996) Oxford University Press, Oxford. 100-102.
Summary: A brief chapter summarizing the basic characteristics and properties of hippocalcin.
View information in the CaBP database derived from this reference

Takenaga, K., Nakamura, Y., Sakiyama, S. Expression of a calcium binding protein pEL98 (mts1) during differentiation of human promyelocytic leukemia HL-60 cells (1994) Biochem Biophys Res Comm 202, 94-101.
View information in the CaBP database derived from this reference

Takenga, K., Nakamura, Y., Endo, H., Sakiyama, S. Involvement of S100-related calcium-binding protein pEL98 (or mts1) in cell motility and tumor cell invasion (1994) Jpn J Cancer Res 85, 831-839.
View information in the CaBP database derived from this reference

Tallant, E.A, Cheung, W.Y Characterization of bovine brain calmodulin-dependent protein phosphatase (1984) Arch Biochem Biophys 232, 269-279.
View information in the CaBP database derived from this reference

Tan, R.-Y., Mabuchi, Y., Grabarek, Z. Blocking the Ca2+-induced conformational transitions in calmodulin with disulfide bonds (1996) J Biol Chem 271, 7479-7483.
Summary: This paper described two calmodulin mutants. One domain is ³locked² close by a disulfide bond in each mutant. The mutant with the C-terminal domain locked has decreased Ca2+ affinity in the C-terminal sites, as followed by intrinsic tyrosine fluorescence. Neither mutant is able activate phosphodiesterase or calcineurin..
View information in the CaBP database derived from this reference

Tanaka, T., Ames, J.B, Harvey, T.S, Stryer, L., Ikura, M. Sequestration of the membrane-targeting myristoyl group of recoverin in the calcium-free state (1995) Nature 376, 444-446.
Summary: The reference for pdb entry 1IKU.
View information in the CaBP database derived from this reference

Tanaka, T., Hidaka, H. Hydrophobic regions function in calmodulin-enzyme(s) interactions (1980) J Biol Chem 255, 11078-11080.
No information from this reference is currently stored in the database

Tatusov, R.L, Koonin, E.V, Lipman, D.J A genomic perspective on protein families (1997) Science 278, 631-637.
No information from this reference is currently stored in the database

Taylor, D.A, Sack, J.S, Maune, J.F, Beckingham, K., Quiocho, F.A Structure of a recombinant calmodulin from Drosophila melanogaster refined at 2.2-angstrom resolution (1991) J Biol Chem 266, 21375-21380.
View information in the CaBP database derived from this reference

Teahan, C.G, Totty, N.F, Segal, A.W Isolation and characterization of grancalcin, a novel 28 kDa EF-hand calcium-binding protein from human neutrophils (1992) Biochem J 286, 549-554.
No information from this reference is currently stored in the database

Teigelkamp, S. ., S Bhardwaj, R. ., Roth, J. ., Meinardus-Hager, G. ., Karas, M. ., Sorg, C. . Calcium-dependent complex assembly of the myeloic differentiation proteins MRP-8 and MRP-14 (1991) J Biol Chem 266, 13462-13467.
No information from this reference is currently stored in the database

Terwilliger, T.C, Waldo, G., Peat, T.S, Newman, J.M, Chu, K., Berendzen, J. Class-directed structure determination: Foundation for a protein structure initiative (1998) Protein Sci 7, 1851-1856.
No information from this reference is currently stored in the database

Thomasset, M., L'Horset, F., Blin, C., Lambert, M., Colnot, S., Perret, C. "Calbindin-D9k" in Guidebook to the Calcium-Binding Proteins, M.R.Celio, T.Pauls, B.Schwaller, eds. (1996) Oxford University Press, Oxford. 157-159.
Summary: A brief chapter summarizing the basic properties of calbindin D9k.
View information in the CaBP database derived from this reference

Thordarson, G., Southard, J.N, Talamantes, F. Purification and characterization of mouse decidual calcyclin: A novel stimulator of mouse placental lactogen-II secretion (1991) Endocrinology 129, 1257-1265.
View information in the CaBP database derived from this reference

Thulin, E., Andersson, A., Drakenberg, T., Forsen, S., Vogel, H.J Metal ion and drug binding to proteolytic fragments of calmodulin: proteolytic, cadmium-113, and proton nuclear magnetic resonance studies (1984) Biochemistry 23, 1862-1870.
No information from this reference is currently stored in the database

Tjandra, N., Kuboniwa, H., Ren, H., Bax, A. Rotational dynamics of calcium-free calmodulin studied by 15N-NMR relaxation measurements (1995) Eur J Biochem 230, 1014-1024.
No information from this reference is currently stored in the database

Tokumitsu, H. ., Mizutani, A. ., Hidaka, H. . Calcyclin-binding site located on the NH2-terminal domain of rabbit CAP-50 (annexin XI): functional expression of CAP-50 in Escherichia coli (1993) Arch Biochem Biophys 303, 302-306.
No information from this reference is currently stored in the database

Tokumitsu, H., Kobayashi, R., Hidaka, H. A calcium-binding protein from rabbit lung cytosol identified as the product of a growth-regulated gene (2A9) and its binding proteins (1991) Arch Biochem Biophys 288, 202-207.
View information in the CaBP database derived from this reference

Tokumitsu, H., Mizutani, A., Minami, H., Kobayashi, R., Hidaka, H. A calcyclin-associated protein is a newly identified member of the Ca(2+)/phospholipid-binding proteins, annexin family (1992) J Biol Chem 267, 8919-8924.
No information from this reference is currently stored in the database

Tomida, Y., Terasawa, M., Koayashi, R., Hidaka, H. Calcyclin and calvasculin exist in human platelets (1992) Biochem Biophys Res Comm 189, 1310-1316.
View information in the CaBP database derived from this reference

Topham, C.M, Srinivasan, N., Blundell, T.L Prediction of the stability of protein mutants based on structural environment-dependent amino acid substitution and propensity tables (1997) Protein Eng 10, 7-21.
No information from this reference is currently stored in the database

Torok, K., Trentham, D.R Mechanism of 2-chloro-(e-amino-lys(75))-[6-[4-(N,N-diethylamino)phenyl]-1,3,5-triazin-4-y1]calmodulin interactions with smooth muscle myosin light chain kinase and derived peptides (1994) Biochemistry 33, 12807-12820.
No information from this reference is currently stored in the database

Trave, G., Lacombe, P.-J., Pfuhl, M., Saraste, M., Pastore, A. Molecular mechanism of the calcium-induced conformational change in the spectrin EF-hands (1995) EMBO J 14, 4922-4931.
Summary: Presents NMR structures of apo and calcium-loaded alpha-spectrin EF hand domain, and builds an interesting model for the mechanism of conformational change between the two states.
View information in the CaBP database derived from this reference

Trybus, K.M Role of myosin light chains (1994) J Musc Res Cell Motil 15, 587-594.
No information from this reference is currently stored in the database

Tsai, M.-D., Drakenberg, T., Thulin, E., Forsen, S. Is the binding of magnesium(II) to calmodulin significant? An investigation by magnesium-25 nuclear magnetic resonance (1987) Biochemistry 26, 3635-3543.
No information from this reference is currently stored in the database

Tsuji, T., Kaiser, E.T Design and synthesis of the pseudo-EF hand in calbindin D9k: effect of amino acid substitutions in the alpha-helical regions (1991) Proteins 9, 12-22.
Summary: Reports on a series of synthetic peptides of the pseudo EF-hand of calbindin D9k. The only modification found to increase Ca2+ affinity was the introduction of a disulfide bond.
No information from this reference is currently stored in the database

Urbauer, J.L, Short, J.H, Dow, L.K, Wand, A.J Structural analysis of a novel interaction by calmodulin: high-affinity binding of a peptide in the absence of calcium (1995) Biochemistry 34, 8099-8109.
No information from this reference is currently stored in the database

Uyeda, T.QP., Spudich, J.A A functional recombinant myosin II lacking a regulatory light chain-binding site (1993) Science 262, 1867-1879.
No information from this reference is currently stored in the database

van den Bos, C., Roth, J., Koch, H.G, Hartmann, M., Sorg, C. Phosphorylation of MRP14, an S100 protein expressed during moncytic differentiation, modulates Ca2+-dependent translocation from cytoplasm to membranes and cytoskeleton (1996) J Immunol 156, 1247-1254.
Summary: The second (shorter) MRP-14 isoform was found to be co-translated with full-length MRP-14. Phosphorylation of MRP-14 was found to increase the Ca2+ affinity and to favor localization of MRP-14 to membranes.
View information in the CaBP database derived from this reference

Van der Bliek, A.M, Meyers, M.B, Biedler, J.L, Hes, E., Borst, P. A 22-kd protein (sorcin/V19) encoded by an amplified gene in multidrug-resistant cells, is homologous to the calcium-binding light chain of calpain (1986) EMBO J 5, 3201-3208.
No information from this reference is currently stored in the database

Van Eldik, L. Watterson, D.M. eds. Calmodulin and Signal Transduction (1998) Academic Press, San Diego.
No information from this reference is currently stored in the database

Van Eldik, L.J, Hu, J. "S100B" in Guidebook to the Calcium-Binding Proteins, M.R.Celio, T.Pauls, B.Schwaller, eds. (1996) Oxford University Press, Oxford. 152-155.
Summary: A brief chapter summarizing the basic characteristics and properties of S100B.
No information from this reference is currently stored in the database

Van Eldik, L.J, Zendegui, J.G, Marshak, D.R, Watterson, D.M Calcium-binding proteins and the molecular basis of calcium action (1982) Int Rev Cytol 77, 1-61.
No information from this reference is currently stored in the database

van Heyningen, V. ., Hayward, C. ., Fletcher, J. ., McAuley, C. . Tissue localization and chromosomal assignment of a serum protein that tracks the cystic fibrosis gene (1985) Nature 315, 513-515.
No information from this reference is currently stored in the database

VanBerkum, M.FV., George, S.E, Means, A.R Calmodulin activation of target enzymes: consequences of deletions in the central helix (1990) J Biol Chem 265, 3750-3756.
No information from this reference is currently stored in the database

Vandonselaar, M., Hickie, R.A, Quail, J.W, Delbaere, L.TJ. Trifluoperazine-induced conformational change in Ca(2+)-calmodulin (1994) Nat Struct Biol 1, 795-801.
View information in the CaBP database derived from this reference

Vassylyev, D.G, Takeda, S., Wakatsuki, S., Maeda, K., Maeda, Y. Crystal structure if troponin C in complex with troponin I fragment at 2.3-A resolution (1998) Proc Natl Acad Sci USA 95, 4847-4852.
Summary: The first high resolution structural information about the TnC-TnI complex. There are two Ca2+ ions bound, to TnC-C. The TnI fragment also binds mostly to TnC-C..
View information in the CaBP database derived from this reference

Veenstra, T.D, Johnson, K.L, Tomlinson, A.J, Naylor, S., Kumar, R. Determination of calcium-binding sites in rat brain calbindin D28k by electrospray ionization mass spectrometry (1997) Biochemistry 36, 3535-3542.
No information from this reference is currently stored in the database

Vertessy, B.G, Bocskei, Z., Harmath, V., Naray-Szabo, G., Ovadi, J. Crystallization and preliminary diffraction analysis of Ca2+-calmodulin-drug and apocalmodulin-drug complexes (1997) Proteins 28, 131-134.
No information from this reference is currently stored in the database

Vijay-Kumar, S. ., Kumar, V.D Crystal structure of recombinant bovine neurocalcin (1999) Nature Struct Biol 6, 80-88.
No information from this reference is currently stored in the database

Vijay-Kumar, S., Cook, W.J Structure of a sarcoplasmic calcium-binding protein from Nereis divisicolor refined at 2.0 A resolution (1992) J Mol Biol 224, 413-426.
View information in the CaBP database derived from this reference

Vito, P., Lacana, E., DıAdamio, L. Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimerıs disease gene ALG-3 (1996) Science 271, 521-525.
No information from this reference is currently stored in the database

Vogel, H.J, Lindahl, L., Thulin, E. Calcium-dependent hydrophobic interaction chromatography of calmodulin, troponin C and their proteolytic fragments (1983) FEBS Lett 157, 241-246.
No information from this reference is currently stored in the database

Vogel, H.J, Zhang, M. Protein engineering and NMR studies of calmodulin (1995) Mol Cell Biochem 149/150, 3-15.
Summary: Review focusing on interaction of calcium-loaded calmodulin with its target peptides. Attention is called to possible roles of the flexible central helix and the methionine rich hydrophobic core in allowing calmodulin to bind to many different targets. .
No information from this reference is currently stored in the database

Vorherr, T., Knopfel, L., Hofmann, F., Mollner, S., Pfeuffer, T., Carofoli, E. The calmodulin binding domain of nitric oxide synthase and adenylyl cyclase (1993) Biochemistry 32, 6081-6088.
View information in the CaBP database derived from this reference

Wall, M.E, Clarage, J.B, Phillips, G.NN., Jr. Motions of calmodulin characterized using both Bragg and diffuse X-ray scattering (1997) Structure 5, 1599-1612.
No information from this reference is currently stored in the database

Walsh, M., Stevens, F.C Chemical modification studies on the Ca(2+)-dependent protein modulator: The role of methionine residues in the activation of cyclic nucleotide phosphodiesterase (1978) Biochemistry 17, 3924-3930.
No information from this reference is currently stored in the database

Walsh, M., Stevens, F.C, Oikawa, K., Kay, C.M Circular dichroism studies of native and chemically modified Ca(2+)-dependent protein modulator (1979) Can J Biochem 57, 267-278.
No information from this reference is currently stored in the database

Wang, K.KW., Yuen, P.-W. Calpain inhibiton: an overview of its therapeutic potential (1994) Trends Pharmacol Sci 15, 412-419.
Summary: A review sumamrizing the potential roles of calpain in various disease states..
No information from this reference is currently stored in the database

Wang, X., Culotta, V.C, Klee, C.B Superoxide dismutase protects calcineurin from inactivation (1996) Nature 383, 434-437.
No information from this reference is currently stored in the database

Watanabe, M. ., Ando, Y. ., Tokumitsu, H. ., Hidaka, H. . Binding site of annexin XI on the calcyclin molecule (1993) Biochem Biophys Res Commun 196, 1376-1382.
No information from this reference is currently stored in the database

Watt, K.W, Brightman, I.L, Goetzl, E.L Isolation of two polypeptides comprising the neutrophil-immobilizing factor of human leucocytes (1983) Immunology 48, 79-86.
No information from this reference is currently stored in the database

Weaver, C.D, Crombie, B., Stacey, G., Roberts, D.M Calcium-dependent phosphorylation of symbiosome membrane proteins from nitrogen-fixing soybean nodules (1991) Plant Physiol 95, 222-227.
View information in the CaBP database derived from this reference

Weber, C., Lee, V.D, Chazin, W.J, Huang, B. High level expression in Escherichia coli and characterization of the EF-hand calcium-binding protein caltractin (1994) J Biol Chem 269, 15795-15802.
View information in the CaBP database derived from this reference

Weinstein, H., Mehler, E.L Ca2+-binding and structural dynamics in the functions of calmodulin (1994) Annu Rev Physiol 56, 213-236.
Summary: Review of computational work on the flexibility of calmodulin, its compaction in solution relative to the crystal structure, and its binding to target peptides.
No information from this reference is currently stored in the database

Wendt, B., Hofmann, T., Martin, S.R, Bayley, P., Brodin, P., Grundstrom, T., Thulin, E., Linse, S., Forsen, S. Effect of amino acid substitutions and deletions on the thermal stability and unfolding by urea of bovine calbindin D9k (1988) Eur J Biochem 175, 439-445.
Summary: A report of studies on the temperature and urea stability of the apo form of the following mutants: P20G, N21 removed, P20 removed, Y13F, E17Q, and on the the pH stability of the calcium-loaded states of the same mutants. Little or no change in the stabilities (with respect to wildtype) is found..
View information in the CaBP database derived from this reference

Wery, J.P, Dideberg, O., Charlier, P., Gerday, C. Crystallization and structure at 3.2 angstrom resolution of a terbium parvalbumin (1985) FEBS Lett 182, 103-106.
No information from this reference is currently stored in the database

Weterman, M.AJ., van Muijen, G.NP., Bloemers, H.JP., Ruiter, D.J Expression of calcyclin in human melanocytic lesions (1993) Cancer Res 53, 6061-6066.
No information from this reference is currently stored in the database

Whitfield, J.F, Bird, R.P, Chakravarthy, B.R, Issacs, R.J, Morley, P. Calcium-- cell cycle regulator, differentiator, killer, chemopreventor, and maybe, tumor promoter (1995) J Cell Biochem Suppl 22, 74-91.
Summary: A review focusing on the possible roles of calcium in cancer biology, with an emphasis on effect of calcium on tissues..
No information from this reference is currently stored in the database

Wicki, R., Marenholz, I., Mischke, D., Schafer, B.W, Heizmann, C.W Characterization of the human S100A12 (calgranulin, C, p6, CAAF1, CGRP) gene, a new member of the S100 gene cluster on chromosome 1q21 (1996) Cell Calcium 20, 459-464.
No information from this reference is currently stored in the database

Williams, T.C, Corson, D.C, Oikawa, K., McCubbin, W.D, Kay, C.M, Sykes, B.D (1)H NMR spectroscopic studies of calcium-binding proteins. 3. Solution conformations of rat apo-alpha-parvalbumin and metal-bound rat alpha-parvalbumin (1986) Biochemistry 25, 1835-1846.
No information from this reference is currently stored in the database

Williams, T.C, Corson, D.C, Sykes, B.D, MacManus, J.P Oncomodulin - 1H NMR and optical stopped-flow spectroscopic studies of its solution conformation and metal-binding properties (1987) J Biol Chem 262, 6248-6256.
No information from this reference is currently stored in the database

Wimberly, B., Thulin, E., Chazin, W. Characterization of the N-terminal half-saturated state of calbindin D9k: NMR studies of the N56A mutant (1995) Protein Sci 4, 1045-1055.
No information from this reference is currently stored in the database

Wimley, W., Creamer, T., White, S. Solvation energies of amino acid side chains and backbone in a family of host-guest pentapeptides (1996) Biochemistry 35, 5109-5124.
No information from this reference is currently stored in the database

Winningham-Major, F., Staecker, J.L, Barger, S.W, Coats, S., Van Eldik, L.J Neurite extension and neuronal survival activities of recombinant S100b proteins that differ in the content and position of cysteine residues (1989) J Cell Biol 109, 3063-3071.
View information in the CaBP database derived from this reference

Wintrode, P.L, Privalov, P.L Energetics of target peptide recognition by calmodulin: a calorimetric study (1997) J Mol Biol 266, 1050-1062.
Summary: The thermodynamic properties of ca2+-loaded calmodulin binding to a target peptide derived from smMLCK were measured. The binding process was found to be driven by enthalpy..
No information from this reference is currently stored in the database

Wjst, M. ., Immervoll, T. . An internet linkage and mutation database for the complex phenotype asthma (1998) Bioinformatics 14, 827-828.
No information from this reference is currently stored in the database

Wojcik, J., Goral, J., Pawlowski, K., Bierzynski, A. Isolated calcium-binding loops of EF-hand proteins can dimerize to form a native-like structure (1997) Biochemistry 36, 680-687.
No information from this reference is currently stored in the database

Wright, R.L, Salisbury, J., Jarvik, J.W A nucleus-basal body connector in Chlamydomonas reinhardtii that may function in basal body localization or segregation (1985) J Cell Biol 101, 1903-1912.
No information from this reference is currently stored in the database

Wu, X., Reid, R.E Structure/calcium affinity relationships of site III of calmodulin: Testing the acid pair hypothesis using calmodulin mutants (1997) Biochemistry 36, 8649-8656.
No information from this reference is currently stored in the database

Xie, X., Harrison, D.H, Schlichting, I., Sweet, R.M, Kalabokis, V.N, Szent-Gyorgyi, A.G, Cohen, C. Structure of the regulatory domain of scallop myosin at 2.8 angstrom resolution (1994) Nature 368, 306-312.
Summary: Structure of scallop myosin light chains and portion of the heavy chain. The structure has since been refined to a higher resolution.
View information in the CaBP database derived from this reference

Yagi, K., Yazawa, M., Minowa, O., Toda, H., Ikura, M., Hikichi, K. Significance of domain structure of calmodulin on the activation of Ca2+-Calmodulin-Regulated Enzymes (1988) Adv Second Messenger Phosphoprotein Res 21, 189-192.
Summary: Proposes that binding of CaM to target peptide switches the two CaM domains to a correlated mode. Ca2+ binding to the N-terminal domain (which only occurs after the C-temrinal domain has been saturated) causes a further conformational change in the C-temrinal domain,a s probed by proton chemical shifts..
No information from this reference is currently stored in the database

Yakel, J.L Calcineurin regulation of synaptic function: from ion channels to neurotransmitter release and gene transcription (1997) Trends Pharmacol Sci 18, 124-134.
No information from this reference is currently stored in the database

Yasuda, T., Banville, D., Hendy, G.N, Goltzman, D. Characterization of the human parathyroid hormone-like peptide gene: functional and evolutionary aspects (1989) J Biol Chem 264, 7720-7725.
No information from this reference is currently stored in the database

Yaswen, P., Smoll, A., Peehl, D.M, Trask, D.K, Sager, R., Stampfer, M.R Down-regulation of a calmodulin-related gene during transformation of human mammary epithelial cells (1990) Proc Natl Acad Sci USA 87, 7360-7364.
View information in the CaBP database derived from this reference

Yip, P., Case, D.A A new method for refinement of macromolecular structures based on nuclear Overhauser effect spectra (1989) J Magn Reson 83, 643-648.
No information from this reference is currently stored in the database

Yoshimura, N., Tsukahara, I., Murachi, T. Calpain and calpastatin in porcine retina. Identification and action on microtubule-associated protein (1984) Biochem J 223, 47-51.
View information in the CaBP database derived from this reference

Yoshino, H., Minari, O., Matsushima, N., Ueki, T., Miyake, Y., Matsuo, T., Izumi, Y. Calcium-induced shape change of calmodulin with mastoparan studied by solution X-ray scattering (1989) J Biol Chem 264, 19706-19709.
No information from this reference is currently stored in the database

Yoshino, H., Wakita, M., Izumi, Y. Calcium-dependent changes in structure of calmodulin with substance P (1993) J Biol Chem 268, 12123-12128.
No information from this reference is currently stored in the database

Young, M.F, Kerr, J.M, Ibaraki, K., Heegaard, A.-M., Robey, P.G Structure, expression, and regualtion of the major noncollagenous matrix proteins of bone (1992) Clin Orthop 281, 275-294.
No information from this reference is currently stored in the database

Yuan, T. ., Walsh, M.P, Sutherland, C. ., Fabian, H. ., Vogel, H.J Calcium-dependent and -independent interactions of the calmodulin-binding domain of cyclic nucleotide phosphodiesterase with calmodulin (1999) Biochemistry 38, 1446-1455.
No information from this reference is currently stored in the database

Yui, S. ., Mikami, M. ., Tsurumaki, K. ., Yamazaki, M. . Growth-inhibitory and apoptosis-inducing activities of calprotectin derived from inflammatory exudate cells on normal fibroblasts: regulation by metal ions (1997) J Leukoc Biol 61, 50-75.
No information from this reference is currently stored in the database

Zamparelli, C., Ilari, A., Verzili, D., Vecchini, P., Chiancone, E. Calcium- and pH-linked oligomerization of sorcin causing translocation from cytosol to membranes (1997) FEBS Lett 409, 1-6.
No information from this reference is currently stored in the database

Zeng, F.-Z., Gabius, H.-J. Carbohydrate-binding specificity of calcyclin and its expression in human tissues and leukemic cells (1991) Arch Biochem Biophys 289, 137-144.
No information from this reference is currently stored in the database

Zeng, F.-Z., Gerke, V. ., Gabius, H.-G. Identification of annexin II, annexin VI and glyceraldehyde-3-phosphate dehydrogenase as calcyclin-binding proteins in bovine heart (1993) Int J Biochem 25, 1019-1027.
No information from this reference is currently stored in the database

Zhang, M., Li, M., Wang, J.H, Vogel, H.J The effect of met --> leu mutations on calmodulinıs ability to activate cyclic nucleotide phosphodiesterase (1994) J Biol Chem 269, 15546-1552.
Summary: Reports the activity of a series of met to leu mutants of calmodulin, using PDE activation as an assay. Also presents some NMR data indicating that the calcium-loaded structures of the mutants are similar to wildtype..
View information in the CaBP database derived from this reference

Zhang, M., Tanaka, T., Ikura, M. Calcium-induced conformational transition evealed by the solution structure of apo calmodulin (1995) Nat Struct Biol 2, 758-767.
View information in the CaBP database derived from this reference

Zhang, M., Vogel, H.J Determination of the side chain pKa values of lysine residues in calmodulin (1993) J Biol Chem 268, 22420-22428.
No information from this reference is currently stored in the database

Zhang, M., Vogel, H.J Two-dimensional NMR studies of selenomethionyl calmodulin (1994) J Mol Biol 239, 545-554.
Summary: Reports on chemical shift changes of selenium in selenomethionyl calmodulin upon calcium binding and also upon binding of a target peptide..
No information from this reference is currently stored in the database

Zhang, M., Yuan, T., Aramin, J.M, Vogel, H.J Interaction of calmodulin with its binding domain of rat cerebellar nitric oxide synthase (1995) J Biol Chem 270, 20901-20907.
No information from this reference is currently stored in the database

Zhou, N., Yuan, T., Mak, A.S, Vogel, H.J NMR studies of caldesmon-calmodulin interaction (1997) Biochemistry 36, 2817-2825.
Summary: Reports NMR and CD studies on the binding of calmodulin to four peptides derived from the putative calmodulin-binding sites of caldesmon.
View information in the CaBP database derived from this reference

Zimmer, D.B, Cornwall, E.H, Landar, A., Song, W. The S100 protein family: History, function and expression (1995) Brain Res Bull 37, 417-429.
No information from this reference is currently stored in the database

Zimmer, D.B, Dubuisson, J.G Identification of an S100 target protein: glycogen phosphorylase (1993) Cell Calcium 14, 323-332.
View information in the CaBP database derived from this reference

Zimmer, D.B, Van Eldik, L.J Identification of a molecular target for the calcium-modulated protein S100. Fructose-1,6-bisphosphate aldolase (1986) J Biol Chem 261, 11424-11428.
View information in the CaBP database derived from this reference

Zot, H.G, Potter, J.D A structural role for the Ca2+-Mg2+ sites on troponin C in the regulation of muscle contraction: preparation of troponin C depleted myofibrils (1982) J Biol Chem 257, 7678-7683.
View information in the CaBP database derived from this reference

---

CaBP Data Library Home Page| General Info| Sequence Info| Structural Info| Analysis Tools
Top of Current Section| Search the Data Library| Site Map| Feedback