References about Calpain

References about Calpain

Please note: this is not intended to be a complete listing of references.

See the home page for Calpain for more information.

Blanchard, H., Grochulski, P., Li, Y., Arthur, S.C, Davies, P.L, Elce, J.S, Cygler, M. Structure of a calpain Ca2+-binding domain reveals a novel EF-hand and Ca2+-induced conformational changes (1997) Nat Struct Biol 4, 532-538.
Summary: The paper for PDB entries 1AJ5 and 1DV1. It presents the structures of apo and calcium-loaded domain VI of calpain, and a preliminary analysis of the calcium-induced conformational changes, whicha re unlike any of the previously described conformational responses to calcium-binding..
View information in the CaBP database derived from this reference

Blanchard, H., Li, Y., Cygler, M., Kay, C.M, Arthur, J.SC., Davies, P.L, Elce, J.S Ca2+-binding domain VI of rat calpain is a homodimer in solution: hydrodynamic, crystallization and preliminary X-ray diffraction studies (1996) Protein Sci 5, 533-537.
Summary: The initial report of crystallization of rat calpain domain VI. The paper includes studies that show this domain to form homodimers in solution.
No information from this reference is currently stored in the database

Crawford, C., Brown, N.R, Willis, A.C Studies of the active site of m-calpain and the interaction with calpastatin (1993) Biochem J 296, 135-142.
No information from this reference is currently stored in the database

Croall, D.E, Demartino, G.N Calcium-activated neutral protease (calpain) system: structure, function, and regulation (1991) Physiol Rev 71, 813-847.
Summary: An extensive and careful review..
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Goll, D.E, Thompson, V.F, Taylor, R.G, Zalewska, T. Is calpain activity regulate by membranes and autolysis or by calcium and calpastatin? (1992) BioEssays 14, 549-556.
Summary: A review arguing that the hypothesis that calpain is regulated by mebranes and autolysis is unable to explain all of the experimental data..
No information from this reference is currently stored in the database

Lin, G.-d., Chattopdhyaya, D., Masatoshi, M., Wang, K.KW., Carson, M., Jin, L., Yuen, P.-w., Takano, E., Hatanaka, M., DeLucas, L.J, Narayana, S.VL. Crystal structure of calcium bound domain VI of calpain at 1.9 A resolution and its role in enzyme assembly, regulation, and inhibitor binding (1997) Nat Struct Biol 4, 539-547.
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Mellgren, R.L Calcium-dependent proteases: an enzyme system active at cellular membranes? (1987) FASEB J 1, 110-115.
Summary: Review of the possible roles of calpains in membrane fusion, memory storage and long-term potentiation, and the proteolytic activation of protein kinase C..
No information from this reference is currently stored in the database

Murachi, T. Calpain and calpastatin (1983) Trends Biochem Sci 8, 167-169.
Summary: A short review giving the basics about the calpain-calpastatin system.
No information from this reference is currently stored in the database

Nishimura, T., Goll, D.E Binding of calpain fragments to calpastatin (1991) J Biol Chem 266, 11842-11850.
No information from this reference is currently stored in the database

Ohno, S., Minoshima, S., Kudoh, J., Fukuyama, R., Shimuzu, Y., Ohmi-Imajoh, S., Shimuzu, N., Suzuki, K. Four genes for the calpain family on four distinct human chromosomes (1990) Cytogenet Cell Genet 53, 225-229.
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Wang, K.KW., Yuen, P.-W. Calpain inhibiton: an overview of its therapeutic potential (1994) Trends Pharmacol Sci 15, 412-419.
Summary: A review sumamrizing the potential roles of calpain in various disease states..
No information from this reference is currently stored in the database

Yoshimura, N., Tsukahara, I., Murachi, T. Calpain and calpastatin in porcine retina. Identification and action on microtubule-associated protein (1984) Biochem J 223, 47-51.
View information in the CaBP database derived from this reference