CaBP Data Library General Information

ALG-2

Primary information about ALG-2:
Basic chemical and physical information
Basic biological information
Basic genomic information
Metal ion binding constants
Interspecies sequence alignment
Information on function
Summary of structural studies
Information on the conformational change List of available structures Information about mutations
References about ALG-2 Other web resources about ALG-2

Basic Information

Additional names and abbreviations: No additional names are stored in the database
Isoforms: No information about isoforms is stored in the database
Yeast Protein Database Entries: No links to the YPD are stored in the database


Basic Chemical and Physical Information:
Number of amino acids: 191 (all species)
View a list of all sources stored in the database
Molecular weight: 21.867 kD (all species)
View a list of all sources stored in the database
pI: not yet available in the data library
Number of functional calcium binding sites: not yet available in the data library
Macroscopic calcium binding constants: not yet available in the data library
Other metal binding constants: not yet available in the data library
Protein stability: not yet available in the data library
Post-translational modifications: not yet available in the data library


Basic Biological Information:
Source organisms: Mus musculus
View an annotated list of all sources stored in the database
Tissues: not yet available in the data library
Subcellular localization: not yet available in the data library
Regulation: not yet available in the data library


Genomic Information:
GenBank entries: not yet available in the data library
Gene length: not yet available in the data library
Gene structure: not yet available in the data library
Promoter: not yet available in the data library
Gene copies: not yet available in the data library
Alleles: no alleles are currently stored in the data library
Chromosomal localization: not yet available in the data library

Interspecies Sequence Alignment



                                  |-helixI-|--loop1----|helixII-|
                                   En**nn**nX*Y*ZG#Ix**zn**nn**n*

MOUSE  : MAAYSYRPGPGGGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDNELQQALSNGT

                |helixIII|--loop2----|helixIV| 
                En**nn**nX*Y*ZG#Ix**zn**nn**n*  

MOUSE  : WTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYIT

         |helixV-|-loop3-----|helixVI-|
         En**nn**nX*Y*ZG#Ix**zn**nn**n*

MOUSE  : DWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQ

        |helixVII|--loop4-----|hlxVIII|-hlxIX--|--loop5----|-helixX-|
         En**nn**nX*Y*ZG#Ix**zn**nn**n*En**nn**nX*Y*ZG#Ix**zn**nn**n*

MOUSE  : FHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSIV


Sequence alignment for entire calpain subfamily

Functional Information:

General information:

Biological roles:

Disease states:

Target molecules:


Structural Information:

Calcium-coordination:
not yet available in the data library


Nature of the conformational changes:
not yet available in the data library


Secondary structure:
(as reported in the PDB file and its accompanying reference)
not yet available in the data library


Additional structural information:
no additional structural information is currently stored in the database


Available structures:
(follow the links from the PDB code to the retrieve the
PDB files)
no structures are currently stored in the database

Information about mutants: