Information from the EF-Hand CaBP Database about Calmodulin Mutant F65A + F68A

Engineered mutant of isoform 1 calmodulin, from Saccharomyces cerevisiae (InfoCard)

This mutant causes a dose-suppressible temperature sensitive phenotype in Saccharomyces cerevisiae in which it is the only form of calmodulin (InfoCard)

No physical properties of this mutant are currently stored in the database

	Target Protein	Acitivation Ability	Percent Activation (compared to wt)	K(act) (nM)
F65A + F68A	calcineurin	yes (InfoCard)	64 % (InfoCard)	81 (InfoCard)
wildtype from Saccharomyces cerevisiae		yes (InfoCard)	100 % (InfoCard)	61 (InfoCard)