Information from the EF-Hand CaBP Database about Calmodulin Mutant M72L

Engineered mutant of isoform 1 calmodulin, from Bos taurus (InfoCard)

This mutant form of CaM can fully activate PDE, but must be present at higher concentrations than required for wildtype CaM to achieve full PDE activation (InfoCard)

No physical properties of this mutant are currently stored in the database

	Target Protein	Acitivation Ability	Percent Activation (compared to wt)	K(act) (nM)	V(max)
M72L	calmodulin-dependent cyclic nucleotide phosphodiesterase	yes (InfoCard)