Information from the EF-Hand CaBP Database about Calmodulin Mutant A128G

Engineered mutant of isoform 1 calmodulin, from Bos taurus (InfoCard)

Shows near wildtype ability to activate myosin light chain kinase (93% of max), but reduced ability to activate nitric oxide synthase (79% of max) (InfoCard)

No physical properties of this mutant are currently stored in the database

	Target Protein	Acitivation Ability	Percent Activation (compared to wt)	K(act) (nM)
A128G	smooth muscle myosin light chain kinase	partial (InfoCard)	93 % (InfoCard)
wildtype from Bos taurus		yes (InfoCard)	100 % (InfoCard)	1.5 (InfoCard)

A128G	neuronal nitric oxide synthase	partial (InfoCard)	79 % (InfoCard)