The information presented here was taken from Nakayama,S., N. Moncrief, and R. Kretsinger, (1992) J. Mol. Evol. 34, 416-448 and Nakayama, S. and R. Kretsinger (1994) Annu. Rev. Biophys. Biomol. struct. 23, 473,507. However, any inaccuracies are my own.
The S100 family is congruent. The following tree was constructed using both EF hands and the linker:
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