AMBER Archive (2003)

Subject: Re: May I get your help?

From: David A. Case (case_at_scripps.edu)
Date: Thu Jul 10 2003 - 22:05:21 CDT

On Wed, Jul 09, 2003, Wu Yingliang wrote:
>
> I have a docked protein complex from rigid docking program. It is necessary
> to build NMR constraints to refine protein complex? I will appreciate very
> much warm-hearted direction for me as a new user of Amber7.

I don't really understand the question. Do you have NMR data that you wish
to interpret, or refine structures into. The answer will probably also depend
upon what you mean by "refine the protein complex", i.e. on what you are
planning to do with the results; it will also depend on how "bad" the initial
strucutre you have is (i.e. how far away from some "correct" answer it is.)

..hope this helps...dac 

-- 

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David A. Case                     |  e-mail:      case_at_scripps.edu
Dept. of Molecular Biology, TPC15 |  fax:          +1-858-784-8896
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