An Introductory Workshop for Hybrid Methods with Rosetta

March 6, 2015

Workshop Goals

The goal of the workshop is to introduce Rosetta and some of the tools it has availible for hybrid structural biology methods to attendees of the Hybrid Methods in Structural Biology Keystone Symposium. Rosetta is freely distributed to the academic community by RosettaCommons. (See https://www.rosettacommons.org/software/license-and-download) Industry usage includes licensing fees that support research and development of Rosetta software.

Workshop Format

The format of the workshop will be "live demo". Presenters will give a brief introduction, followed by worked examples.
Presenter list:
  • Rocco Moretti, Chemistry and the Center for Structural Biology, Vanderbilt University (rocco.moretti@vanderbilt.edu)
  • Nik Sgourakis, Laboratory of Chemical Physics, NIDDK, NIH (sgourakisn@mail.nih.gov)
  • Frank Dimaio, Biochemisty and the Institute of Protein Design, University of Washington (dimaio@u.washington.edu)
  • Ray Wang, Biochemisty and the Institute of Protein Design, University of Washington (wangyr@uw.edu)

Preparation

If you wish to follow along during the live demo on your own computer, you may want to download and compile Rosetta. Rosetta needs to be installed in a Unix-like environment, such as Linux or MacOS. If you are using a Microsoft Windows laptop, we recommend running Linux under a virtualization machine environment such as VirtualBox or VMware Player

Other programs you may want to have are Python 2.7, PyMol, Perl, and R.


The files used in the demonstrations are availible for download: