Past CSB News Articles

Andrzej Krezel, MBTP/CSB Seminar 10/20/09

Andrzej Krezel presents: "Structural Biology of Transcription in Helicobacter pylori" 1220 MRBIII, 12:30pm

Gerald Stubbs, MBTP/CSB Seminar 10/6/09

Gerald Stubbs presents: “Natural and synthetic prion structure from X-ray fiber diffraction� MRBIII, Room 1220, 12:30pm

Jessica Vey, MBTP/CSB Seminar - 9/15/09

Jessica Vey presents: "Structural Basis for Glycyl Radical Formation by Pyruvate Formate-lyase Activating Enzyme" MRBIII, Room 1220, 12:30pm

Wade Van Horn, MBTP/CSB Seminar - 9/1/09

Wade Van Horn presents: "Solution NMR Structure of Membrane-Integral Diacylglycerol Kinase" MRBIII, Room 1220, 12:30pm

Patrick Robertson, MBTP/CSB Seminar 8/18/09

Patrick Robertson presents: “Solution NMR Structure of the C-Terminal Domain of Xenopus laevis Mcm10 Reveals a Novel Zn2 DNA Binding Motif� MRBIII, Room 1220, 12:30pm

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Ben Spiller, MBTP/CSB Seminar 8/4/09

Ben Spiller presents: "VirA, Shigella, and the Host Cytoskeleton" MRBIII, Room 1220, 12:30pm

Christina Williams, MBTP/CSB Seminar 7/21/09

Christina Williams presents: "Structural and Dynamic Analysis of SV40 J domain Interactions� MRBIII, Room 1220, 12:30pm

Mariena Silvestry Ramos, Dissertation Defense, 7/9/09

"Insight into Adenovirus Programmed Disassembly From CryoEM: The Structures of Ad2ts1 and the Ad35f+Defensin HD5 Complex" Thursday, July 9, 2009, 10:00 a.m. 202 Light Hall

Major breakthrough for the Sanders Lab

Chuck Sanders and his group have completed the solution NMR structure of DAGK. The work is published in the latest issue of Science. See the press release at: http://www.mc.vanderbilt.edu/news/releases.php?release=940 Congratulations on this wonderful achievement!!

Andrzej Krezel, MBTP/CSB Seminar Series 7/7/09

Andrzej Krezel presents: "Structural Biology of Transcription in Helicobacter pylori" MRBIII, Room 1220, 12:30pm

Sarah Musser, MBTP/CSB Seminar 6/16/09

Sarah Musser presents: "Structural Investigations of Stereoisomeric N3-deoxyuridine DNA Adducts Arising from Butadiene Monoepoxide" MRBIII, Room 1220, 12:30pm

Borden Lacy, MBTP/CSB Seminar Series 6/2/09

Borden Lacy presents: “Bacterial protein toxin entry into host cells: Mechanisms of pore formation and translocation” MRBIII, Room 1220, 12:30pm

Tim Panosian, MBTP/CSB Seminar 5/19/09

Tim Panosian presents: “Move it move it; the structure and mechanism of a phosphopentomutase” MRBIII, Room 1220, 12:30pm

Andrew Link, MBTP/CSB Seminar Series 5/5/09

Andrew Link presents: “Systematic Proteomic Analysis of Eukaryotic Translation Complexes” MRBIII, Room 1220, 12:30pm

Diane Kanter, MBTP/CSB Seminar Series 4/21/09

Diane Kanter presents: “The role of Dpb11 in DNA metabolism” MRBIII, Room 1220, 12:30pm

Tina Iverson, MBTP/CSB Seminar Series 4/7/09

Tina Iverson presents: "The outer membrane protein PorB from Neisseria meningitidis: from structure to function to disease" MRBIII, Room 1220, 12:30pm

Dalyir Pretto, MBTP/CSB Seminar Series 3/17/09

Dalyir Pretto presents: "Investigating Domain Flexibility and Intersubunit interactions in Replication Protein A" MRBIII, Room 1220, 12:30pm

Phoebe Stewart, MBTP/CSB Seminar Series 3/3/09

Phoebe Stewart presents: "Visualizing the Structures and Conformational Changes of Biological Nanomachines with CryoEM" MRBIII, Room 1220, 12:30pm

Emily Rubinson MBTP/CSB Seminar Series 2/17/09

Emily Rubinson presents: "A New Architecture for Locating and Excising Alkylpurines from DNA: The Crystal Structure of DNA Repair Protein AlkD" MRBIII, Room 1220, 12:30pm

Eichman wins Sigma Xi’s Young Investigator Award

Brandt Eichman was named the winner of the 2008 Sigma Xi Award to recognize research excellence within ten years of earning his or her highest degree. See link at: http://sitemason.vanderbilt.edu/news/releases/2009/01/29/vanderbilt-biochemist-receives-2009-sigma-xi-award.71862

Laura Mizoue, MBTP/CSB Seminar Series 2/3/09

Laura Mizoue presents: "In search of: hidden domains in the transcription factor HoxA11" MRB III, Room 1220, 12:30pm

Katie Germane MBTP/CSB Seminar Series 1/20/09

Katie Germane presents: “Structural and Functional Analysis of Shigella flexneri Virulence Factor VirA” MRB III, Room 1220, 12:30pm

Symposium in Memory of Anne Karpay - 1/23/09

Symposium in Memory of Anne Karpay: Gunning for Membrane Proteins January 23, 2009 2:30-5:30, 1220 MRBIII Speakers: James Bowie (UCLA), Douglas Rees (Caltech), Stanley Opella (UCSD) Karpay Symposium Poster

Paul Bock, MBTP/CSB Seminar Series 1/6/09

Paul Bock presents: "Focusing on the Invisible Parts of the Mechanism of Plasminogen Activation by Streptokinase" MRBIII, Room 1220, 12:30pm

Eichman and Chazin research sheds new light on eukaryotic DNA replication machinery

Recent research directed by Professor Brandt Eichman has elucidated some of the first atomic details of a protein involved in replicating DNA in eukaryotic organisms.

Duplication of DNA each time a cell divides is one of the most fundamental processes in biology. However, due to the complexity and size of the multi-protein machine that drives DNA replication, the mechanisms by which eukaryotes orchestrate the synthesis of daughter from parental DNA is largely unknown. The Eichman lab determined the crystal structure of the DNA binding domain of one essential replisome component, Mcm10, and in collaboration with Walter Chazin and Anja Bielinsky (University of Minnesota), has uncovered the manner in which this domain interacts with DNA and its importance in replication.

Featured on the cover of the December, 2008 issue of Structure (Cell Press), this research integrates X-ray crystallography, NMR spectroscopy, biochemistry, and yeast genetics, and will be an important starting point for understanding the details of one of nature’s most fundamental processes.

Read More | Multimedia Version

Matt Tyska MBTP/CSB Seminar Series 12/2/08

Matt Tyska presents: "A novel role for actin-based motor proteins in the regulation of cell membrane mechanics" MRB III, Room 1220, 12:30pm

John Tainer, Ph.D. MBTP Guest Speaker, November 18,

Guest Speaker John Tainer, Ph.D. Professor, Department of Molecular Biology and The Skaggs Institute for Chemical Biology presents: "XPD and Mre11/Rad50/Nbs1 ATPase Complexes: Structural Insights into the Cancer and Aging Phenotypes from Mutations of these Genome Guardians". Tuesday, November 18, 12:30pm MRB 3, Rm 1220.

Stubbs lab research could lead to new ways to improve crop yields

A recent interdisciplinary study directed by Professor Gerald Stubbs has yielded the first detailed information about the structure of the most destructive group of plant viruses known: flexible filamentous viruses.

The cost of worldwide crop losses due to plant diseases is estimated at $60 billion annually. Although there are no good estimates of the cost of plant viruses alone, the viruses are generally considered to be the second greatest contributor to those losses (after fungi). The 300-plus species of flexible filamentous viruses are responsible for more than half of all virus damage.

The findings are published in the October 1 issue of the Journal of Virology and could lead to new ways to protect crop plants from these viruses.

Read More   |  Multimedia Version

MBTP/CSB Seminar Series Dave Piston, Ph.D. November 4, 2008

Dave Piston presents: "Systems Biology of a Model Multicellular System" 12:20pm, MRB 3, Room 1220

David Eisenberg, DPhil. Bircher Lecture, October 27, 4:20pm

David Eisenberg, DPhil presents: "Structural Biology of Amyloids and Prions". Refreshments at 4p in 7330A SC (the Chemistry Dept. Conference Room), and a reception to immediately follow the lecture, also in 7330A SC.

Nathan Alexander MBTP/CSB Seminar Series 10/21/08

Nathan Alexander of Jens Meiler Lab presents: "Incorporation of Experimental Restraints with Protein Structure Prediction". MRB 3, Room 1220. 12:20pm

John Wikswo presents MBPT Seminar September 30 12:20

John Wikswo presents: “The possibility of automated, on-line inference of metabolic networks". Tuesday, September 30, 12:20 in MRB 3, Room 1220

Rory Pruitt Presents MBTP Seminar Series September 16

Rory Pruitt of Borden Lacy Lab presents:"Structural and Functional Studies of Large Clostridial Cytotoxins" MRB 3, Room 1220, 12:15pm.

Richard Armstrong presents MBTP lecture 9/9/08

Richard Armstrong, Ph.D. Editor in Chief, Journal of Biochemistry Will lead a discussion on: "Ethics in Publication" All students actively supported by the MB training grant are required to attend this special seminar Tuesday, September 9, 2008 **NOTE TIME EXTENSION** 12:20 – 1:55pm Lunch available at 12:10 Seminar begins at 12:20 **MRB III, Room 1220**

Dewight Williams, presents at MBTP Seminar 8/26/08

Dewight Williams, Ph.D. presents: "The DNA-dependent protein kinase catalytic subunit structure determined by electron cryomicroscopy to < 10 Angstroms resolution." Tuesday, August 26, 2008 12:20 – 1:20pm Lunch available at 12:10 Seminar begins at 12:20 **MRB III, Room 1220**

Liliana Wroblewska - TALK CANCELLED

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Liliana Wroblewska Meiler, Post-doc candidate speaks 8/19, 12:20

Molecular Biophysics Training Program Seminar Series / Center for Structural Biology Liliana Wroblewska Post-doc candidate Meiler Lab presents: "Refinement of protein models with all-atom force fields" Tuesday, August 19, 2008 12:20 – 1:20pm Lunch available at 12:00 Seminar begins at 12:20 **MRB III, Room 1220**

MBTP/CSB Seminar Kristian Kaufman, 8/12, 12:20pm MRB 3, Room 1220

Molecular Biophysics Training Program Seminar Series / Center for Structural Biology Kristian Kaufman Meiler Lab presents: "A Perspective on Computational Prediction of Interfaces Between Proteins and Small Molecules: Simultaneous Optimization of Protein Side Chain and Small Molecule Degrees of Freedom" Tuesday, August 12, 2008 12:20 – 1:20pm Lunch available at 12:00 Seminar begins at 12:20 MRB III, Room 1220

Brenda Schulman, talk August, 11, 2008, 4:00pm

Brenda Schulman, Ph.D. Investigator, Howard Hughes Medical Institute Assoc. Member, St. Jude Children’s Research Hospital presents, “Conformational Control in the dynamic Processes of Ubiquitin-Like Protein Conjugation” Monday, August 11, 2008 4:00 – 5:00 pm Stevenson Center, Room 5502

Iverson receives prestigous award

Congratulations to Tina Iverson, who has been selected to receive a Young Investigator award from the National Alliance for Research on Schizophrenia and Depression. This is for work to study the mechanisms for the sensing of dopamine.

Gunter Fritz, Ph.D. presents CSB/MBTP Seminar 7/29/08

Molecular Biophysics Training Program Seminar Series / Center for Structural Biology Guenter Fritz, Ph.D. Privat Dozent, Assistant Professor University of Konstanz, Germany Presents: “Insights into receptor activation from structural biology of the receptor RAGE and its ligands” Tuesday, July 29, 2008 12:00 – 1:00pm Lunch available at 11:45 Seminar begins at 12:00 **MRB III, Room 1220**

Meiler co-authors Science paper on conformational variability

Jens Meiler was part of a team that used residual dipolar couplings (RDCs)and computation to show the conformational variation of the small protein ubiquitin. This study demonstrates the power of using the RDC parameter to characterize slow conformational dynamics up to the msec time scale. The results were also significant in lending support to the concept that structural changes required for binding are already being sampled through the fluctuations of the free protein.

Gunnar Jeschke, Ph.D. presents: “Structural models of membrane proteins from pulsed EPR distance mea

The Center for Structural Biology, Department of Chemistry, and Molecular Physiology and BioPhysics are pleased to host: Gunnar Jeschke, Ph.D. ETH Zurich Laboratory for Physical Chemistry Who will present: “Structural models of membrane proteins from pulsed EPR distance measurements” Friday, August 1, 2008 11:30 – 12:30pm. Tentative Location: MRB 3, Room 1220

Tennessee Structural Biology Symposium

Tennessee Structural Biology Symposium begins with registration from 12:00 - 2:00 on Friday, June 20, 2008 in the Peabody Commons. Please see the website for additional information. http://structbio.vanderbilt.edu/TSBS5/

Benjamin Chagot presents the MBTP Seminar Series, June 17, 12:00pm

“How do the intrinsic (EF-hand domain of hH1) and extrinsic (calmodulin) Ca2+ sensors regulate gating of the human cardiac sodium ion channel hH1?”. SC 5502, 12:00pm - 1:30pm lunch served at 11:45.

Chuck Mobley Defense, June 12, 2008 3:00 pm, SC5502

"Biophysical Studies of Human Neuorolgical Membrane Proteins"

Brian Weiner Defense; Monday, June 9, 2:00pm, 1220 MRB 3

"Biochemical and structural analysis of the p58C and p68N domains of DNA polymerase alpha/primase".

MBTP/CSB Seminar Larry Marnett

Larry Marnett, Ph.D. presents: "Dynamics of Cyclooxygenase-Inhibitor Interactions - Origins of Potency and Selectivity of Binding" 12:00 in the Stevenson Center 5502

Tenneessee Structural Biology Sympoisum

The 5th Annual TN Structural Biology Symposium will be held Friday, June 20th and Saturday, June 21st at the Peabody Commons. Please see the TN Structural Biology Symposium website for additional information at: http://structbio.vanderbilt.edu/TSBS5/

Update title of Miko Tanabe May 20 talk

"Structural studies of the outer membrane porin PorB from Neisseria meningitidis"

Miko Tanabe presents at MBTP May 20

Miko Tanabe of the Iverson Lab Presents: “Understanding pathogen recognition mechanism by TLRs the way to determine crystal structure of outer membrane porin” Tuesday, May 20, 2008 12:00 – 1:00pm Lunch available at 11:45 Seminar begins at 12:00 Stevenson Center 5502

Hassane Mchaourab, Ph.D. Presents at MBTP May 6, 2008

Molecular Biophysics Training Program Seminar Series / Center for Structural Biology Hassane Mchaourab, Ph.D. Presents: “Living with Controversies: A Tale of two Transporters” Tuesday, May 6, 2008 12:00 – 1:00pm Lunch available at 11:45 Seminar begins at 12:00 Stevenson Center 5502

Kurt Wuthrich, Ph.D., Nobel Laureate in Chemistry April 17

Kurt Wüthrich, Ph.D. Cecil H. and Ida M. Green Professor of Structural Biology, The Scripps Research Institute, La Jolla, CA Professor of Biophysics, ETH Zürich, Zürich, Switzerland Speaking on: “New Trends in NMR Spectroscopy for Structural Biology and Structural Genomics” Thursday, April 17, 2008 12:30 – 1:30pm MRB III, Room 1220

Brian Bachmann presents MBTP/CSB Seminar Series, April 1, 12:00pm

Brian O. Bachmann, Ph.D. of Vanderbilt Chemistry Department Presents: “Discovery of pharmacophore biosynthesis enzymes in bacteria”. Tuesday, April 1, 2008. 12:00 pm.

MBTP/CSB Seminar Series, March 18, 12:00pm

Brian Weiner, Chazin Lab, Presents: “Biochemical and structural analysis of the p58C and p68N domains of DNA polymerase alpha/primase”. Lunch available at 11:45 - Seminar begins at 12:00 Stevenson Center 5502

Rachel Klevit, D. Phil., Biochemistry Monday Seminar Series

Rachel Klevit, D. Phil., Dept of Biochemistry University of Washington, Seattle, WA presents: Specificity and Diversity in the Function of BRCA1/BARD1 Ubiquitin E3 Ligase Monday, March 17, 2008 4:00 PM - 512 Light Hall Sponsored by: Department of Biochemistry, the Center for Structural Biology, and The National Cancer Institute Training Grant "Biochemical and Chemical Training for Cancer Research" Refreshments served at 3:45 p.m.

Kurt Wuthrich, Ph.D., Nobel Laureate in Chemistry April 16

Cecil H. and Ida M. Green Professor of Structural Biology, The Scripps Research Institute, La Jolla, CA, USA Professor of Biophysics, ETH Zürich, Zürich, Switzerland. April 16, 2008 (Wednesday) Lecture - "The NMR view of Proteins" Sponsor: Center for Structural Biology 4:00 p.m. / 208 Light Hall

MBTP/CSB Seminar Series, March 4, 12:00pm

Claus Schneider presents: "Old and not so old substrates for probing the mechanism of cyclooxygenases". Stevenson Center Room 5502.

Kelly Conrads, ForteBio, Inc., February 20, 1pm

Jamshid Khoshnoodi hosts Kelly Conrads from ForteBio, Inc. to hold a seminar in PRB Room 317 on the Bio-Layer Interferometry & the Octet System Label-Free Protein Affinity, Kinetics, and Quantitation in Crude or Purified Samples Topics to be covered include:KINETICS Applications - Fast alternatives to Biacore Therapeutics R&D - Protein/Protein Interaction Analysis - Affinity characterization - Measure kinetic constants - Rank order affinities - Fast Kinetic Screening of Binding Proteins/Peptides and Antagonists QUANTITATION Applications - Fast Alternatives to HPLC and ELISA -Antibody Quantitation in 30 Minutes - Rapid Concentration Analysis from Tissue or Cell Culture Extracts ASSAY DEVELOPMENT, Protein-Protein Interactions

MBTP/CSB Seminar Series, February 19, 12:00pm

Dorothee Kern, Brandeis University to speak

Professor Walter Chazin will host Dorothee Kern of Brandis University on April 7, 2008, 4:15-5:30 p.m. at 5211 Stevenson Center.

Anne Karpay Memorial

Memorial Service for: Anne Karpay 1981-2008 IGP Student, Biochemistry Ph.D. Candidate Thursday, January 17, 4:15pm Light Hall 208

MBTP/CSB Seminar Series, February 5, 12:00pm

Heidi Hamm, Ph.D. Presents: "How receptors activate G proteins" 12:00 - 1:30 pm, SC5502

MBTP/CSB Seminar Series, January 15, 12:00pm

Nils Woetzel, Jens Meiler Lab presents, “Computational Protein Structure prediction using knowledge based energy functions and experimental restraints”. MRBIII, Room 1220.

Special NMR Seminar 9 AM Friday, January 18

"Strategies for Structure Determination of a Weak Binding, Fast Exchanging Carbohydrate-Protein Complex". Tiandi Zhuang, Prestegard Lab, University of Georgia, 9 AM, Friday January 18, Rm 5131 MRBIII. The talk will consist of two parts: 1. enhancement of RDCs through specific association between alkyl chain and alignment media. 2. Use of Paramagnetism-based constraints (RDC,PCS). Tiandi is a Sanders lab postdoc candidate.

Special CSB Seminar - Friday August 3, 2007

Dr. Ning Zheng, Presents:“Ubiquitin Ligase Machinery:from Plant Biology to Human Disease” Friday, August 3, 2007 12:00 – 1:30pm Stevenson Center Room 5202 Lunch available at 11:45 Seminar begins at 12:00

Guengerich Presents July 3, 2007, 12:00pm

F. Peter Guengerich, Ph.D. Presents: “Kinetic and structural approaches to understanding interactions of carcinogens, DNA, & DNA polymerases” in Stevenson Center Room 5502 from 12:00 - 1:30pm

Jian Shi, speaks June 19, 12:00pm, SC 5502

Jian Shi Stewart Lab Presents: “Mechanistic Insight of a structural study of Small Heat Shock Protein variants by cryo-electron microscopy” Tuesday, June 19, 2007 12:00 – 1:30pm Lunch available at 11:45 Seminar begins at 12:00 Stevenson Center, Room 5502

Walter Chazin receives Stanley Cohen Award for Outstanding Contributions to Research

The 2007 Faculty Awards, presented at the Spring Faculty Meeting, recognize excellence in teaching and in research. The awards for Outstanding Contributions to Research are named in honor of current and past Vanderbilt faculty who were recognized during their careers by election to the National Academy of Sciences.

The Stanley Cohen Award — For Research Bridging Diverse Disciplines, such as Chemistry or Physics, to Solve Biology‘s Most Important Fundamental Questions - was awarded to CSB director Walter Chazin, Ph.D., professor of Biochemistry, Chemistry; Ingram Professor of Cancer Research.

Congratulations!

Anne Kenworthy, May 1, 2007, 12:00pm SC5502

Anne Kenworthy Presents:“Biophysical analysis of membrane microdomains”. Tuesday, May 1, 2007, 12:00 – 1:30pm. Lunch available at 11:45, Seminar begins at 12:00. Stevenson Center, Room 5502

Tennessee Structural Biology Symposium, June 21-23, 2007

Tennessee Structural Biology Symposium, Doubletree Hotel Murfreesboro, TN. June 21-23, 2007. For registration form contact lori.michalowski@vanderbilt.edu.

Markus Godejohann from Bruker Biospin

SPECIAL PRESENTATION: Markus Godejohann from Bruker Biospin Presents:“Theory and practice of LC-SPE-NMR/MS” Tuesday, May 8, 2007 12:00 – 1:30pm Seminar begins at 12:00 Stevenson Center, Room 5502

OPEN House

Guest Speakers: Dr. Kathy Gould presents: "Determining the architecture of a subcomplex within the spliceosome"; Dr. Timothy Cover presents: "Investigation of Helicobacter pylori and gastric cancer: a structural biology approach"; Dr. Daniel Liebler presents: “Protein targets of damage by reactive electrophiles” Friday, November 10, 2006, 1220 MRB III, 2:30 — 4:30 pm Reception to follow in 1st floor foyer

Dr. Zhen Huang, speaks at CSB/MBTP Seminar, October 3, 2006

Zhen Huang, Ph.D. Associate Professor Department of Chemistry of Georgia State University presents: “Synthesis of Selenium Nucleic Acids (SeNA) for Structure and Function Studies of Nucleic Acids”. Structure determination of RNAs, DNAs, and their protein complexes, which are potential drug targets, can provide insights on their structures and functions. X-ray crystallography is a powerful tool for the 3-D structure determination of these biomacromolecules although heavy atom derivatization for phase determination, a long-standing major problem in X-ray crystallography, has largely slowed down structural determination of nucleic acids with novel folds. In order to help solving this problem, we have first developed chemical and enzymatic syntheses of RNAs and DNAs derivatized with selenium by site-specifically replacing oxygen. We will present the chemical synthesis and enzymatic incorporation study of RNA and DNA containing Se-modifications, and present the structure study of the Se-modified DNAs and RNAs. This strategy of RNA and DNA derivatization with selenium has great potential as a general methodology in X-ray crystallography. This novel strategy will significantly facilitate nucleic acid X-ray crystallography and study of nucleic acid-protein complexes.

Abbas Ourmazd lecture November 17, 3:00pm

Dr. Ourmazd is a very astute microscopist deep into the underlying physics of diffraction, especially with electron beams. He will give a lecture on "Crystallography without crystals: Deteriming the structure of biological molecules". Friday, November 17, 2006 at 3:00pm Stevenson Center, Physics 5th floor conference room (SC 6524).

P. Shing Ho, Ph.D. visits Vanderbilt

P. Shing Ho, Ph.D. of Oregon State University presents: "Halogen bonds: An orthogonal interaction to hydrogen bonds?" On Tuesday, September 5th 12:00 - 1:30 in Stevenson Center room 5502. Dr. Ho will also be presenting: "From Holliday junctions to halogen bonds" at the VICB seminar 12:15 - 1:15 in MRB 3 1220.

Vanderbilt Center for Structural Biology and Thermo Electron present, Larry DeLucas, O.D., Ph.D,

Larry J. DeLucas, O.D., Ph.D, D.Sc.(hon.) Director, The Center for Biophysical Sciences and Engineering Director and Senior Scientist, UAB Comprehensive Cancer Center X-ray Crystallography Facility The University of Alabama, Birmingham speaking on: “Advanced Technologies to Improve Expression/Crystallization for Difficult Proteins” Several interrelated technologies employed at the CBSE are improving the success rate with difficult proteins. The following will be discussed: 1. An advanced protein expression system that has demonstrated the ability to produce mg quantities of membrane (and aqueous) proteins. Recent success will be shown with the Cystic Fibrosis Transmembrane Regulator (CFTR) Protein. 2. A new HTP analytical method for measuring Protein-Protein & Protein-Drug interactions that utilizes 2nd virile coefficient measurements as a quantitative predictor for protein crystallization and protein stability. This alternative method uses nanogram amounts with rapid quantitative outcomes that overcome the limitations typically associated with Static Light Scattering. 3. Several strategies will be discussed for the optimization of crystals including the use of neural networks and capillary counter diffusion techniques. Traditional individual capillary experiments require manual preparation & tedious harvesting procedures that currently make it secondary for those seeking HTP solutions. A new automated technology developed at the center will be described that embraces all of the advantages of a true liquid-liquid diffusion environment. 4:00 pm Tuesday, June 20, 2006 Room 1220 Biological Sciences/MRB III

Introduction to CSB Resources

The CSB will host a seminar on Friday, April 7 from 2:00 - 4:00pm in PRB 206 to give an overview of the resources available in the CSB for those in the research community. Light refreshments will be provided.

Zhao wins SER-CAT award

Our very own Bin Zhao has been selected to receive the 2006 SER-CAT Outstanding Science Award! The award comes with an invitation to speak at the annual SER-CAT symposium, which will be held this year at Georgia State University on March 10th.

Lacy to give invited talk at National Biodefense Meeting

One of our two newest colleagues, Borden Lacy, has been invited to give a talk at the Fourth Research Conference on Biodefense in Washington DC. The conference is held annually by the American Society of Microbiology and provides a forum for cutting edge research advances in the field of biodefense attracting leading experts from all over the world. The title of her talk is “Anthrax Toxin Receptors/Inhibitors”. It will be given as part of the Plenary Session on The Role of Structural Biology in Biodefense.

Molecular Biophysics Training Program Seminar

Brian Datillo, Chazin Lab presents, "The Modular Structure of RAGE and its Macromolecular Interactions."

Structural Biology Mini-Symposium, Dec. 1, 2005 2-4pm

2:00 pm Topic: A Tale of Two Macromolecular Assemblies by 3D Electron Microscopy Speaker: Phoebe Stewart, PhD Institution: VUMC Seminar Location: MRB3, Room 1220. 3:00 pm Topic: Trying to Elucidate Mechanisms of Eukaryotic Translation Initiation Speaker: Gerhard Wagner, PhD Institution: Harvard Medical School Seminar Location: MRB3, Room 1220

CSB Open House

The Center for Structural Biology will be holding an Open House on November 11. Presentations from 2-4 PM in 1220 BIOSCI/MRBIII will be followed by personalized tours of the facilities and a reception. All students, staff and faculty are encouraged to come by and learn about opportunities to apply structural biology approaches to their research and access cores and facilities.

CSB Biomolecular Visualization Workshop - Oct. 12-13, 2005

The CSB will host a two-session workshop in Biomolecular Visualization on October 12-13 from 1-4pm. This is an introductory workshop and assumes no prior knowledge or experience in the areas of molecular modeling or visualization. Beginners are encouraged to participate, as this is the target audience for this workshop. The fee for this workshop is $75, and will be limited to 13 participants.

Please visit the workshop website for a syllabus and more details.

Tennessee Structural Biology Symposium - September 9-10, 2005

TENNESSEE STRUCTURAL BIOLOGY SYMPOSIUM

Center for Structural Biology
Vanderbilt University
BIOSCI/MRB III; Room 1220

September 9-10, 2005
Starts at 5:00 PM on Friday

Keynote Speaker
James H. Prestegard, Ph.D.
Eminent Scholar Professor
University of Georgia

For details contact:
M. Sundaramoorthy, Ph.D.
Lori Michalowski

Sponsored by:
FEI Company
James River Technical
Cambridge Isotope Laboratories
GE Healthcare
Bruker Biospin

Molecular Biophysics Training Program Seminar Series

Chu Wang, Graduate Student from University of Washington, Biochemistry Presenting “Predicting Protein-protein Interactions by RosettaDock” on: Tuesday, September 6, 2005 12:00 – 1:25pm Room SC5326.

Molecular Biophysics Training Program Seminar Series August 16, 2005

Kristina Furse presents,

Sanders Lab produces folded GCPR in E. coli

The paper shows excellent quality NMR spectra obtained for vasopressin V2 receptor expressed in E. coli!!! Solution NMR spectroscopy of the human vasopressin V2 receptor, a G protein-coupled receptor. Tian C, Breyer RM, Kim HJ, Karra MD, Friedman DB, Karpay A, Sanders CR, J Am Chem Soc 2005 Jun 8 127(22):8010-1. See also citation in Faculty of 1000: http://www.facultyof1000.com/article/15926814

Molecular Biophysics Training Program Seminar Series July 5, 2005

Jens Meiler, Ph.D., Assistant Professor Presents “Protein Ligand Interfaces – From Flexible Docking to Enzyme Design” Tuesday, July 5, 2005 12:00 – 1:25pm Chemistry Building, Room 5502

Krezel and coworkers publish structure of RNP C coiled-coil

The Krezel group has just reported a high resolution solution NMR structure of the RNP C coiled-coil domain. See Journal of Molecular Biology, Vol. 350, Iss. 2, 2005, pages 319-337.

CSB researchers determine structural basis of multi-drug resistance transporter

Congratulations to the Mchaourab lab (Dong J, Yang G, McHaourab HS), who published a major breakthrough in the May 13 issue of Science entitled, Structural basis of energy transduction in the transport cycle of MsbA.

Potential Function Parameter Development Workshop

The Center for Structural Biology will teach a workshop in Potential
Function Parameter Development. This workshop is aimed at researchers who
wish to use molecular mechanics calculations to investigate the structure
and behavior of biomolecular systems.

The fee for this workshop is $100. Advance registration is required due to
limited capacity in the molecular modeling teaching lab. Please visit our
website for a more detailed description and links to the registration
page:

http://structbio.vanderbilt.edu/comp/workshops/parmdev/

The three-hour workshop will be held Wed. Feb. 16 from 1:30-4:30PM, hosted
in the College of Arts and Science Molecular Modeling Teaching Laboratory
(5119 Stevenson Center). Topics covered include:

- The mathematical expressions used in typical potential functions
- The physical justification for these expressions
- Strategies and procedures for development of suitable potential function
parameters
- Applications and limitations of typical potential functions used for
biomacromolecular calculations.

Recent Discoveries in Biochemistry Seminar Series, Murthy Karra, Ph.D.

Dr. Murthy Karra will present a seminar in association with the Recent Discoveries in Biochemistry Seminar Series. His title is Structure Determination of Membrane Proteins Using NMR: Challenges and Progress. The seminar will be held on Thursday, February 3, 2005 at 4:00 in Room 836 RRB. Refreshments will be served.

Dean's Lecture Series, John C. Gore, Ph.D. Invited Speaker

John C. Gore, Ph.D. is invited speaker for the Dean\'s Lecture Series. Dr. Gore is Chancellors University Professor and Director of the Vanderbilt University Institute of Imaging Science. His title is New Horizons in Biomedical Imaging Science. The seminar will be Wednesday, February 2 at 12:00 Noon in 202 Light Hall. Lunch will be provided to RSVP email janelle.owens@vanderbilt.edu

Special VICB Mini-Symposium Wed. Feb 2

Vanderbilt Institute of Chemical Biology is hosting a Mini-Symposium on Wednesday, February 2, 2005. The invited speakers are Dennis Dougherty of California Institute of Technology and Jeffrey Kelly of Scripps Research Institute.
Dr. Dougherty\'s title is Understanding Drug-Receptor Interactions in the Nervous System. Dr. Kelly\'s title is Protein Misfolding Disease Mechanisms and Small Molecule Intervention.
Please join us to hear these two prominent scientists at 3:00 in MRB III; Room 1220.

Molecular Biophysics Training Program Seminar, Dr. Michael Waterman Speaker

Dr. Michael Waterman, Professor and Chariman of Biochemistry at Vanderbilt University School of Medicine is the invited speaker for the Molecular Biophysics Training Program Seminar on Tuesday, February 1, 2005. His title is “Sterol 14α-Demethylase: A Cytochrome P450 Which is an Important Drug Target”. The seminar is held at 12:00 in the Chemistry Building, Room 5502. Lunch will be provided. For additional information please contact rita.r.urben@vanderbilt.edu.

Special Biochemistry Seminar, Hartmut Oschkinat Speaker

On Friday, January 28th at 12:00 Noon Hartmut Oschkinat with the Department of NMR - Supported Structural Biology Forshungsinstitut fur Molekulare Pharmakologie; Berlin, Germany will present a special seminar sponsored by the Biochemistry Department. Seminar title is Proteins and their Interactions Studied by Solutions and Solid-State NMR. The seminar will be held in Room 206 PRB.

Department of Biochemistry Seminar Thursday, January 27, 2005 Carmen A. Perez Speaker

The Department of Biochemistry has invited Carmen A. Perez to present a seminar as part of the Recent Discoveries in Biochemistry Seminar Series. The title of the seminar is Defining the Function of p63 in Breast Myoepithelial Cells. The seminar will be held Thursday, January 27th at 4:00 in Room 836 RRB. Refreshmnets will be served.

Special Lecture; John Dani, Ph.D. Chancellor\'s Chair Candidate

Dr. John Dani, Professor Department of Neuroscience, Menninger Dept of Psychiatry & Behavioral Science, Program in Structural & Computational Biology & Molecular Biophysics of Baylor College of Medicine will present a seminar on Tuesay, January 25th at 10:00AM in 208 Light Hall. Dr. Dani is a candidate for the Chancellor\'s Chair. His title is Cholinergic and Dopaminergic Mechanisms Contributing to Nicotine Addition.

Institute of Chemical Biology ,David Gin Seminar

David Gin of the University of Illinois, Urbana Champaign Department of Chemistry will present a seminar on Wednesday, January 26th at 12:15 in Room 1220; BSB/MRB III. His title is Exploring Strategies for Carbohydrate and Alkaloid Synthesis. For additional information contact Anne.B.Lara@Vanderbilt.edu.

Professor Wolfgang Driever Seminar

The Departments of Biological Science and the Developmental Biology Program and Fish Initiative have invited Professor Wolgang Driever to present a seminar. Dr. Driever is Hans Spemann Professor of Developmental Biology at Freiburg University in Germany. His title is Developmental Neurogenetics in Zebrafish: Cell Specification in the Dopaminergic and Noradrenergic Systems. The seminar will be Thursday, January 27th at 12:15pm in Room 1220 BSB/MRB III.

Department of Biological Sciences Seminar, Chris Janetopoulos, Ph.D.

Faculty candidate Dr. Chris Janetopoulos of Johns Hopkins University School of Medicine is invited speaker on Monday, January 24th at 4:10; Room 1220 BSB/MRB III. His title is Polarity Circiuts in Migrating and Dividing Cells.

Biochemistry Seminar, Speaker Tim Stearns, Ph.D.

Dr. Tim Stearns of Stanford University is the guest speaker on Monday, January 24th for
Biochemistry 337: Molecular Aspects of Cancer Research Spring 2005 Seminar Series. He is an Associate Professor of Biological Sciences and Genetics. His title is Centrosomes and the Cell Cycle. The seminar is at 4:00 in 202 Light Hall.

Center in Molecular Toxicology Seminar, John T.Stivers, Ph.D.

James T. Stivers,Ph.D. Associate Professor of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine is invited speaker on Friday, January 21, 2005 at 4:00; 512 Light Hall.
His title is Dynamic Opening of DNA During the Enzymatic Search for a Damaged Base.

Molecular Biophysics Traininig Program Seminar

Dr. Laura Busenlehner is the invited speaker for the Tuesday, January 18th Molecular Biophysics Training Program Seminar. Her title is Extension of Amide H/D Exchange Mass Spectrometry to Membrane Proteins. The seminar will be at 12:00 in the Chemistry Building, Room 5502.(Note this is a new location). Lunch will be provided. For additional information please contact Rita Urben, rita.r.urben@vanderbilt.edu

Scientist Receive AAAS Honor

NASHVILLE, Tenn. – Four Vanderbilt scientists – Walter J. Chazin, Director, Center for Structural Biology, Raymond N. Dubois Jr., Leonard C. Feldman and Dennis G. Hall – have been elected as fellows of the American Association for the Advancement of Science (AAAS), an honor bestowed upon them by their peers. They are being honored for contributions to research that runs the gamut from determining the atomic structure of proteins to paving the way for improved treatments of digestive diseases including colon cancer, from investigating the atomic structure of materials to providing new insights into the fundamental nature of light.

For entire article, please see: Article

Mini-Symposium, Thursday, December 16, 2004

The Center for Structural Biology is hosting a Mini-Symposium
Thursday, December 16, 2004
1:00 - 3:40pm
MRB III; Room 1220

Program
1:00 “Welcome”
Walter Chazin,Director, Center for Structural Biology

1:10 “New Opportunities for Neutron Structural Biology and Dynamics”
Dean Myles, Director, Center for Structural Biology, Oak Ridge National Laboratory

2:00 “The Structural Enzymology of Parkinson’s Disease”
Gregory Petsko, Gyula and Katica Tauber Professor of Biochemistry and Molecular Pharmacodynamics, Brandeis University

2:50 “Integrated Computational Biology: From the Molecule to the Cell”
Andrew McCammon, Joseph E. Mayer Chair of Theoretical Chemistry, University of Cailifornia, San Diego

3:40 Informal Reception in Main Foyer

KaiC structure from Egli lab on the cover of Molecular Cell

The structure of cyanobacterial clock protein KaiC determined by CSB faculty member was Martin Egli and coworkers appears on the cover of the August 13 issue of Molecular Cell. The structure has revealed important insights into the workings of the circadian clock and the linkage to gene expression. This study is a collaboration with Carl Johnson from the Dept. of Biological Science.

SGI/Vanderbilt Press Release

SGI has issued a press release announcing our partnership with them in building a visualization center around their Onyx4 technology. See it here.

The facility consists of an 8-processor, 4-graphics pipe Onyx4 system, an SXGA passive stereo projector, and two 24-inch 1600x1024 widescreen active stereo CRTs. It is currently hosted by the College of Arts and Science in the molecular modeling teaching laboratory.

CSB Open House!!

Please mark you calendars for Friday afternoon November 5 for a Center for Structural Biology Open House.

Oral presentations, visiting, tours and special prizes.

Watch for more information on these pages and in future announcements.

Bowie seminars: April 21 and 22

James Bowie, Associate Professor in the
Departments of Chemistry and Biochemistry at UCLA will
give 2 lectures:

SAM Domain Polymers and the Construction of
Regulatory Complexes
Wednesday April 21, 2004
12:15pm, 1220 MRBIII

Membrane Protein Stability
Thursday April 22, 2004
3:00pm, 5131 MRBIII

Co-sponsored by the Center for Structural Biology and the
Institute of Chemical Biology

Sanders shows importance of membrane protein folding in disease

DataCentric Automation Seminar, Feb. 24

5131 MRBIII 10-11:30 a.m.
Dave Riling, General Manager of DataCentric
Automation, Nashville will present a seminar
covering the Rhombix Opus. There will be an open
discussion of the technology used to make a Solution
Based System, DCAs current efforts in automation of
protein expression and purification and the extension
of Rhombix to include X-ray diffraction data.

Rhombix Opus is an integrated system with a
common repository for data that improves the speed
and control of a crystallographers work by providing
a comprehensive tool for setting experimental design
parameters, automating protocols, and analyzing
results.

DataCentric Automation and the Biomolecular
Crystallography Facility in the Center for Structural
Biology are entering into a partnership to build an
integrated system for crystallography in the academic
environment.

Light Scattering Technology Seminar: Feb. 10th

Ron Myers from Wyatt Technology Corporation will present a seminar on Multi-angle light scattering (MALS) and Quasi-elastic light scattering (QELS) theory, instrumentation, and applications for macromolecules.

MALS is routinely used to determine biopolymer molar masses and radii, protein aggregation, protein glycosylation, critical micelle concentrations, polymer branching, polymer shape, and polymer viscosity.

QELS can be used to determine the hydrodynamic radii of biopolymers with radii as low as 1 or 2 nm thus making it an excellent complement to MALS.

Tuesday, February 10, 2004
10-11am
5131 MRBIII

Kovall Seminar - January 15 at 3:30

Faculty Candidate Dr. Rhett Kovall has been invited to present a seminar. Dr. Kovall is currently in the Department of Biochemistry and Molecular Biophysics at the Howard Hughes Medical Center at Columbia University.

PLEASE NOTE THIS TIME CHANGE! Refreshments will be available at 3:15.

Data visualization technology demo - Wed. Nov 12

See SGI demonstrate their new graphics supercomputer, the Onyx4, right here at Vanderbilt! Information on the Onyx4 is available at SGI's website. It will be set up in tandem with JRTI's VizEveryWhere 3D immersive projection system. The demo will start at 1:30 and last approximately 90 minutes. We will meet in 5119 Stevenson Center (first floor of the science and engineering building). If you have a current or future need for data visualization, please come and show your interest!

CSB Social Hour

The Vanderbilt Center for Structural Biology

Traditional StructBio Gathering
(Free Food, Beverages, and Camaraderie)

Friday, September 19, 2003
4:30-6:00 P.M. 
5th Floor, Biological Sciences/MRB III 

Seminar Announcement

Dr. James Keck, Asst. Prof., University of Wisconsin, Madison
Department of Biomolecular Chemistry

"Structural dissection of E. coli RecQ DNA helicase reveals physical insights into the molecular basis of Bloom's, Werner's, and Rothmund-Thompson syndromes"

Thursday, September 18, 2003 at 4:10 pm
1220 BioSCI/MRBIII

This seminar is co-sponsored by the Dept. of Biological Sciences and the Center for Structural Biology.

Center for Structural Biology Fellowship Announcement

The Center for Structural Biology (CSB) invites applications for graduate student and postdoctoral fellowships. The fellowship provides salary support to develop projects that use structural and biophysical approaches to address biological problems. Preference will be given to proposals designed to advance projects to the stage that demonstrates feasibility of structural analysis by NMR and/or X-ray crystallography.
Candidates from CSB laboratories are not eligible to apply.

• The postdoctoral stipend is $32,000/year plus full benefits; graduate students will be paid in accord with their home department policy.
• 100% of the recipient's effort must be directed towards the proposed research.
• The recipient can be a new or existing Vanderbilt postdoc or graduate student.
• The recipient must be in place by December 1, 2003.
• The fellowship is for 1 year of funding, although competitive renewal for a second year is possible.
• Full access to CSB equipment and instrumentation is included as part of the fellowship.
• Guidance from highly experienced CSB staff and faculty is available at all stages.
• The recipient will be required to submit progress reports to the CSB every 3 months.

Those selected for further review will be asked to submit a 3 page proposal due on October 6, 2003. Funds will be made available as soon as the decisions are made, no later than October 15, 2003.

Please submit applications to the Center for Structural Biology, 5142 BIOSCI/MRBIII. Questions can be directed to: Laura Mizoue (x6-2253).

Center for Structural Biology Annual Report

The Annual Report for fiscal 2002/2003 is now available. Please contact Melba Carpenter to obtain a copy.

Gerald Stubbs leads new fibre diffraction network

A network of fiber diffraction groups has been established to coordinate activities in the USA. The goal of the network is to develop biological fiber diffraction methods, particularly computational methods. This will be done through a program of software development, and through a series of retreats and workshops. The network software will be complementary to CCP13 software; together, they will eventually cover all aspects of biological fiber diffraction.

A major focus of activity will be cooperation between fiber diffractionists in the USA and others, particularly those in Britain. A second focus will be the coordinated use of the BioCAT X-ray beamline facility at the Advanced Photon Source, Argonne National Laboratory. Network meetings will include three types of activity: retreats that will formalize a successful informal series held sporadically since 1989, workshops at BioCAT, and partial sponsorship of sessions organized by the fiber diffraction Special Interest Group of the American Crystallographic Association.

The network, formally known as Research Coordination Network: Fiber Diffraction from Biological Polymers and Assemblies, and informally as FiberNet, is supported by the National Science Foundation\'s Division of Molecular and Cellular Bioscience, through grant MCB-0234001.

Structbio Gathering: 15 November 2002

Thanks to Kristina Furse for her artistic efforts.

Vanderbilt Biomolecular Modeling Symposium

The Center for Structural Biology at Vanderbilt University will host a biomolecular modeling symposium and poster session on Friday and Saturday, September 20-21, 2002. Registration is required, but free (see below). Refreshments will be provided for the poster session on Friday night. Continental breakfast will be provided before the symposium on Saturday morning. The poster session will be judged, and the winner will receive a prize in the amount of $250. To participate in the contest, check the appropriate box on the registration page and enter your poster's title and abstract in the space provided. Be sure to sign up quickly as seating will be limited to about 120. Registration is on a first-come, first served basis. We reserve the right to limit the number of registrants from any single organization to ensure an appropriate cross-section in the attendance, but only if space becomes a problem. The deadline for registration is Friday, September 13, 2002. Please report cancellations to symposia@structbio.vanderbilt.edu by Friday, September 13, 2002 as well.

Structural Biology Social Hour: 14 June 2002

Come and join us for a drink and some munchies at the next general gathering of the Center for Structural Biology.

It will be held on Friday June 14th in the Biochemistry Conference Room (RRB-836) at 4:00 pm. Here is your personal invitation:

Structural Biology Postdoctoral Fellowship Announcement

Vanderbilt University Center for Structural Biology Postdoctoral Funding Opportunity. The Center for Structural Biology invites applications for postdoctoral fellowships. The intent is to encourage faculty to develop projects that use structural and biophysical approaches to address biological problems and to advance projects to the stage that demonstrates feasibility of structural analysis by NMR and/or X-ray crystallography. Funding will be awarded for a 1-year period to support projects from individual investigators or collaborative teams. Competitive renewal for a 2nd year is possible. The stipend is $32,000/year plus full benefits with full access to equipment and instrumentation within the Center. Funding is open to all Vanderbilt faculty. Letters of intent are due on July 1, 2002. Those selected for further review will be asked to submit a three-page proposal due on July 25, 2002. Funds will be made available as soon as the decisions are made, no later than September 1, 2002. Please submit applications to the Center for Structural Biology (PRB 896). Questions can be directed to: Dr. Laura Mizoue, (6-2253) l.mizoue@vanderbilt.edu

Seminar Announcement

Prediction of Peptide Binding to Families of Related Receptors, presented by Dr Vladimir Brusic, Thursday, 2:00 P.M., May 16, 2002 at Vanderbilt University, 836 RRB. Synopsis: Major histocompatibility complex (MHC) molecules bind peptides and present them on cell surface for recognition by T cells of the immune system. MHC molecules are encoded by genes that show significant polymorphism. In humans, there are more than 500 characterised allelic variants of MHC for each MHC class I and class II. We developed a prediction system called MULTIPRED that was trained using virtual sequences that represent peptide-MHC interactions. The virtual sequences were constructed by combining the interaction sites from both peptide (ligand) and the receptor (MHC) inferred from the three-dimensional structure of MHC molecules. We applied the MULTIPRED system to a selection of human MHC class II molecules HLA-DR, and to the human MHC class I superfamily HLA-A2. MULTIPRED showed high accuracy in predicting HLA-binding peptides. In addition, we have shown that MULTIPRED can accurately predict peptide binding to HLA molecules for which no binding data are available. Biographical Information: Dr Vladimir Brusic is a research manager and the Head of the BioDiscovery Group at the Laboratories for Information Technology, Singapore. His current work includes computational modelling of biological systems, computational simulations of laboratory experiments, biological data warehousing, and functional genomics. Between 1989 and 1998, Dr Brusic was a bioinformatician at the Walter and Eliza Hall Institute in Melbourne, Australia. He has a Doctoral degree in Bioinformatic and Master degrees in Biomedical Engineering, Information Technology, and Business Administration. Dr Brusic has published more than 50 articles in a broad range of bioinformatic fields.

Phase errors in XWINNMR 3.0

Many of you are aware of the recent upgrade of XWINNMR to version 3.0. This software had a bug in the phase incrementation routine and the problem has been fixed. Please refer to VUBNMR News for more information.

Structural Biology Social Hour: 15 March 2002

Come and join us for a drink and some munchies at the next general gathering of the Center for Structural Biology.

It will be held on Friday March 15th in the Biochemistry Conference Room (RRB-836) at 4:00 pm.

Here is your personal invitation:

Center for Structural Biology gathering

Come and join us for a drink and some munchies at the next general gathering of the Center for Structural Biology. It will be held on November 16 in the Biochemistry Conference Room (RRB-836) at 4:00. There will be a brief presentation in the form of a progress report on our development plan and the upcoming move to the new BIOSCI/MRBIII building.

News Site has been Updated!!!

The Structural Biology news center has been updated with two new features..

The first one is an editing feature which allows you to make changes to your submission before you actually submit your article.. The edit button will take you back to your form for you to make changes..

Secondly, when you click the preview button, another page will come up. This page lets you see what your article will look like once its on the internet. The preview page does not mean it has been actually submitted.. Only when you click the submit button is when your article is submitted..

With any questions or comments, email the webmaster by clicking the webmaster link..

thankyou
sravan

Vanderbilt Biomolecular NMR Symposium...

On Saturday October 6, 2001, The Center for Structural Biology will host a biomolecular NMR symposium. Registration is required, but free. Please visit the symposium homepage for more information. Contact vbnmr@structbio.vanderbilt.edu with questions.

A welcome to our readership

Please be sure to make use of this feature. It is a great way for us to stay in contact and updated on progress. And a big thanks to Jarrod and his group for the continued evolution of this website.

Structural Biology Homepage gets a new look...

We've revamped the home page to make it easier to view and navigate. Please send feedback to webmaster@structbio.vanderbilt.edu