CaBP

Interhelical Angles for Calmodulin

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N-terminal domain

Structure
1/2
1/3
1/4
2/3
2/4
3/4
1AHR
mutant form, isoform 1, from Gallus gallus
95.857
-148.373
-143.016
115.567
-145.232
-77.856
1A29
drug bound state, isoform 1, from Bos taurus
93.114
-156.095
116.633
110.726
-42.174
84.027
1AK8
Ce bound state, isoform 1, from Bos taurus
80.328 +/- 3.673
-169.52 +/- 2.49
92.85 +/- 1.649
109.617 +/- 2.376
-30.564 +/- 2.309
95.483 +/- 2.688
1CFC
apo state, isoform 1, from Xenopus laevis
133.9 +/- 1.1
-93.6 +/- 2.3
125.7 +/- 1.2
124.6 +/- 2.8
-50.8 +/- 1.8
128.5 +/- 1.7
1CLL
calcium-loaded state, isoform 1, from Homo sapiens
89.2
-161.3
106.3
109.2
-39.9
87.4
1CLM
calcium-loaded state, isoform 1, from Paramecium tetraurelia
88.377
-158.873
107.201
112.675
-39.247
89.389
1CMF
apo state, isoform 1, from Bos taurus
N/A
N/A
N/A
N/A
N/A
N/A
1CMG
calcium-loaded state, isoform 1, from Bos taurus
N/A
N/A
N/A
N/A
N/A
N/A
1CTR
drug bound state, isoform 1, from Bos taurus
90.636
-156.452
114.723
112.043
-42.914
87.372
1DMO
apo state, isoform 1, from Xenopus laevis
130.9 +/- 2.5
-92.4 +/- 5.2
122.4 +/- 2.1
126.4 +/- 4.1
-55.1 +/- 2.1
131.7 +/- 4.3
1LIN
drug bound state, isoform 1, from Bos taurus
92.311
-155.587
118.339
111.813
-42.32
83.894
4CLN
calcium-loaded state, isoform 1, from Drosophila melanogaster
93.276
-156.016
106.344
110.007
-34.274
96.465

Helical limits:
1AHR: Helix 1: 8 - 18 Helix 2: 29 - 38 Helix 3: 45 - 55 Helix 4: 65 - 80
1A29: Helix 1: 6 - 19 Helix 2: 29 - 38 Helix 3: 45 - 55 Helix 4: 65 - 73
1AK8: Helix 1: 5 - 19 Helix 2: 30 - 39 Helix 3: 45 - 54 Helix 4: 65 - 73
1CFC: Helix 1: 6 - 19 Helix 2: 29 - 38 Helix 3: 45 - 55 Helix 4: 65 - 75
1CLL: Helix 1: 5 - 19 Helix 2: 29 - 37 Helix 3: 45 - 55 Helix 4: 65 - 75
1CLM: Helix 1: 7 - 19 Helix 2: 29 - 38 Helix 3: 45 - 55 Helix 4: 65 - 80
1CMF: N/A
1CMG: N/A
1CTR: Helix 1: 6 - 17 Helix 2: 29 - 38 Helix 3: 45 - 53 Helix 4: 65 - 72
1DMO: Helix 1: 6 - 18 Helix 2: 29 - 39 Helix 3: 45 - 55 Helix 4: 65 - 76
1LIN: Helix 1: 6 - 19 Helix 2: 29 - 39 Helix 3: 45 - 55 Helix 4: 65 - 73
4CLN: Helix 1: 6 - 19 Helix 2: 29 - 36 Helix 3: 45 - 53 Helix 4: 65 - 80


C-terminal domain

Structure
5/6
5/7
5/8
6/7
6/8
7/8
1AHR
mutant form, isoform 1, from Gallus gallus
97.773
-142.891
123.531
115.159
-49.45
92.021
1A29
drug bound state, isoform 1, from Bos taurus
94.991
-149.564
117.677
115.098
-46.766
88.208
1AK8
Ce bound state, isoform 1, from Bos taurus
N/A
N/A
N/A
N/A
N/A
N/A
1CFC
apo state, isoform 1, from Xenopus laevis
132.7 +/- 1.7
-80.6 +/- 1.7
138.8 +/- 2.8
141.5 +/- 1.8
-31.3 +/- 3.3
136.1 +/- 2
1CLL
calcium-loaded state, isoform 1, from Homo sapiens
101.9
-146.1
115.3
111.9
-34.7
94.8
1CLM
calcium-loaded state, isoform 1, from Paramecium tetraurelia
100.991
-146.117
113.835
112.778
-43.055
93.621
1CMF
apo state, isoform 1, from Bos taurus
129.558 +/- 4.47
-98.716 +/- 3.729
120.118 +/- 3.737
125.474 +/- 3.194
-48.474 +/- 3.397
130.326 +/- 3.675
1CMG
calcium-loaded state, isoform 1, from Bos taurus
107.159 +/- 6.064
-151.435 +/- 5.632
110.247 +/- 5.405
100.998 +/- 3.9
-32.232 +/- 4.462
93.854 +/- 6.348
1CTR
drug bound state, isoform 1, from Bos taurus
98.467
-146.059
121.337
115.448
-48.485
84.987
1DMO
apo state, isoform 1, from Xenopus laevis
137 +/- 3.5
-72.5 +/- 4.7
146.9 +/- 3.3
114.8 +/- 3.6
-35.5 +/- 3.3
132.7 +/- 4.7
1LIN
drug bound state, isoform 1, from Bos taurus
95.422
-149.417
115.641
114.686
-44.872
90.934
4CLN
calcium-loaded state, isoform 1, from Drosophila melanogaster
95.991
-148.826
115.155
113.177
-49.101
93.077

Helical limits:
1AHR: Helix 5: 81 - 92 Helix 6: 102 - 112 Helix 7: 118 - 127 Helix 8: 138 - 144
1A29: Helix 5: 82 - 92 Helix 6: 102 - 112 Helix 7: 118 - 128 Helix 8: 138 - 144
1AK8: N/A
1CFC: Helix 5: 82 - 91 Helix 6: 102 - 111 Helix 7: 118 - 127 Helix 8: 139 - 146
1CLL: Helix 5: 82 - 92 Helix 6: 102 - 111 Helix 7: 118 - 128 Helix 8: 138 - 146
1CLM: Helix 5: 81 - 92 Helix 6: 102 - 111 Helix 7: 118 - 128 Helix 8: 138 - 147
1CMF: Helix 5: 83 - 93 Helix 6: 102 - 108 Helix 7: 118 - 128 Helix 8: 138 - 145
1CMG: Helix 5: 82 - 92 Helix 6: 102 - 108 Helix 7: 118 - 128 Helix 8: 138 - 145
1CTR: Helix 5: 83 - 92 Helix 6: 102 - 110 Helix 7: 120 - 128 Helix 8: 138 - 145
1DMO: Helix 5: 82 - 90 Helix 6: 102 - 112 Helix 7: 118 - 127 Helix 8: 138 - 143
1LIN: Helix 5: 82 - 92 Helix 6: 102 - 111 Helix 7: 118 - 128 Helix 8: 138 - 145
4CLN: Helix 5: 81 - 92 Helix 6: 102 - 112 Helix 7: 118 - 126 Helix 8: 138 - 144

See the Available Structures section of the home page for calmodulin for more information about the structures.