References in the EF-hand Calcium-Binding Proteins Data Library

Please note: this is not intended to be a complete listing of references.

Abagyan, R.A, Totrov, M.M Contact area difference (CAD): A robust measure to evaluate accuracy of protein models (1997) J Mol Biol 268, 678-685.
No information from this reference is currently stored in the database

Adelstein, R. Calmodulin and the regulation of the actin-myosin interaction in smooth muscle and nonmuscle cells (1982) Cell 30, 349-350.
No information from this reference is currently stored in the database

Afshar, M., Caves, L.SD., Guimard, L., Hubbard, R.E, Calas, B., Grassy, G., Haiech, J. Investigating the high affinity and low sequence specificity of calmodulin binding to its targets (1994) J Mol Biol 244, 554-571.
No information from this reference is currently stored in the database

Agell, N., Aligue, R., Alemany, V., Castro, A., Jaime, M., Pujol, M.J, Rius, E., Serratosa, J., Taules, M., Bachs, O. New nuclear functions for calmodulin (1998) Cell Calcium 23, 115-121.
Summary: A brief review of propsed functions fo calmodulin in the nucleus, including regulation of cyclin dependent protein kinases and transcription by RNA polymerase III.
No information from this reference is currently stored in the database

Agrafiotis, D.K A new method for analyzing protein sequence relationships based on Sammon maps (1997) Protein Sci 6, 287-293.
Summary: Uses a technique called Sammon mapping to map sequence similarities in the protein kinase superfamily, with a focus on semonstarting the usefulness and validity of this technique of data analysis.
No information from this reference is currently stored in the database

Ahmed, F.R, Przybylska, M., Rose, D.R, Birnbaum, G.I, Pippy, M.E, MacManus, J.P Structure of oncomodulin refined at 1.85 angstrom resolution: an example of extensive molecular aggregation via Ca(2+) (1990) J Mol Biol 216, 127-140.
Summary: later refined to higher resolution.
View information in the CaBP database derived from this reference

Ahmed, F.R, Rose, D.R, Evans, S.V, Pippy, M.E, To, R. Refinement of recombinant oncomodulin at 1.30 angstrom resolution (1993) J Mol Biol 230, 1216-1224.
View information in the CaBP database derived from this reference

Akke, M., Bruschweiler, R., Palmer, A.GN., III. NMR order parameters and free energy: An analytical approach and its application to cooperative Ca2+ binding by calbindin D9k (1993) J Am Chem Soc 115, 9832-9833.
No information from this reference is currently stored in the database

Akke, M., Drakenberg, T., Chazin, W.J Three-dimensional solution structure of Ca2+-loaded porcine calbindin D9k determined by nuclear magnetic resonance spectroscopy (1992) Biochemistry 31, 1011-1020.
Summary: The reference for pdb entry 1CB1.
View information in the CaBP database derived from this reference

Akke, M., Forsen, S., Chazin, W. Solution structure of (Cd(2+)1-calbindin D9k reveals details of the stepwise structural changes along the apo -> (Ca(2+))II,1 -> (Ca(2+))I,II,2 binding pathway (1995) J Mol Biol 252, 102-121.
View information in the CaBP database derived from this reference

Akke, M., Forsen, S., Chazin, W.J Molecular basis for cooperativity in Ca2+ binding in calbindin D9k (1991) J Mol Biol 220, 173-189.
No information from this reference is currently stored in the database

Akke, M., Palmer, A.GN., III. Monitoring macromolecular motions on microsecond to millisecond time scales by R1p - R1 constant relaxation time NMR spectroscopy (1996) J Am Chem Soc 118, 911-912.
No information from this reference is currently stored in the database

Akke, M., Skelton, N.J, Kordel, J., Palmer, A.GN., III., Chazin, W.J Effects of ion binding on the backbone dynamics of calbindin D9k determined by 15N NMR relaxation (1993) Biochemistry 32, 9832-9844.
No information from this reference is currently stored in the database

Alexander, K.A, Cimler, B.M, Meier, K.E, Storm, D.R Regulation of calmodulin binding to P-57 (1987) J Biol Chem 262, 6108-6113.
No information from this reference is currently stored in the database

Alexander, K.A, Wakim, B.T, Doyle, G.S, Walsh, K.A, Storm, D.R Identification and characterization of the calmodulin-binding domain of neuromodulin, a neurospecific calmodulin-binding protein (1988) J Biol Chem 263, 7544-7549.
No information from this reference is currently stored in the database

Alexianu, M.E, Ho, B.-K., Mohamed, A.H, La Bella, V., Smith, R.G, Appel, S.H The role of calcium-binding proteins in selective motoneuron vulnerability in amyotrophic lateral sclerosis (1994) Ann Neurol 36, 846-858.
View information in the CaBP database derived from this reference

Allore, R., O'Hanlon, D., Price, R., Neilson, K., Willard, H.F, Cox, D.R, Marks, A., Dunn, R.J Gene encoding the beta subunit of S100 protein is on chromosome 21: Implications for Down syndrome (1988) Science 239, 1311-1313.
View information in the CaBP database derived from this reference

Allore, R.J, Friend, W.C, O'Hanlon, D., Neilson, K.M, Baumal, R., Dunn, R.J, Marks, A. Cloning and expression of the human S100B gene (1990) J Biol Chem 265, 15537-15543.
View information in the CaBP database derived from this reference

Ames, J.A, Porumb, T., Tanaka, T., Ikura, M., Stryer, L. Amino-terminal myristoylation induces cooperative calcium binding to recoverin (1995) J Biol Chem 270, 4526-4533.
Summary: This paper reports on calcium binding to both myristoylated and unmyristoylated recoverin. Myristoylation was found to lower the calcium affinty and induce cooperativity in calcium binding..
View information in the CaBP database derived from this reference

Ames, J.B, Ishima, R., Tanaka, T., Gordon, J.I, Stryer, L., Ikura, M. Molecular mechanics of calcium-myristoyl switches (1997) Nature 389, 198-202.
Summary: Describes the NMR structure of calcium-loaded myristoylated recoverin, in which calcium is bound to EF-2 and EF-3, and makes some basic comparisons with the apo NMR structure and the crystal strucutre in which one calcium ion is bound..
View information in the CaBP database derived from this reference

Ames, J.B, Tanaka, T., Stryer, L., Ikura, M. Portrait of a myristoyl switch protein (1996) Curr Opin Struct Biol 6, 432-438.
No information from this reference is currently stored in the database

An, J., Nakama, T., Sarai, A. 3DinSight: an integrated relational database and search tool for the structure, function and properties of biomolecules (1998) Bioinformatics 14, 188-195.
Summary: A promising relational database for integrating a variety of information about biomolecules, with a current emphasis on structural and sequence information.
No information from this reference is currently stored in the database

Andersson, M., Malmendal, A., Linse, S., Ivarsson, I., Forsen, S., Svensson, L.A Structural basis for the negative allostery between Ca2+- and Mg2+-binding to the intacellular Ca2_-receptor calbindin D9k (1997) Protein Sci 6, 1139-1147.
Summary: Presents the crystal structures of calbindin D9k with either one magneisum or one manganese ion bound to site II. These two structures adopt similar conformations, unique from the apo or Ca2+-loaded conformations of calbindin. The paper also presents Mg2+-binding constants and Ca2+ constants measured in the presence of Mg2+..
View information in the CaBP database derived from this reference

Andreasen, T.J, Keller, C.H, LaPorte, D.C, Edelman, A.M, Storm, D.R Preparation of azidocalmodulin: a photoaffinity label for calmodulin-binding proteins (1981) Proc Natl Acad Sci USA 78, 2782-2785.
No information from this reference is currently stored in the database

Anglister, J., Ren, H., Klee, C.B, Bax, A. NMR identification of calcineurin B residues affected by binding of a calcineurin A peptide (1995) FEBS Lett 375, 108-112.
No information from this reference is currently stored in the database,,,,,,,,

Archer, S.J, Ikura, M., Torchia, D.A, Bax, A. An alternative 3D NMR technique for correlating backbone 15N with sidechain H--resonances in larger proteins (1991) J Magn Reson 95, 636-641.
No information from this reference is currently stored in the database

Babu, A., Su, H., Ryu, Y., Gulati, J. Determination of residue specificity in the EF-hand troponin C for Ca(2+) coordination, by genetic engineering (1992) J Biol Chem 267, 15469-15474.
No information from this reference is currently stored in the database

Babu, Y.S, Bugg, C.E, Cook, W.J Structure of calmodulin refined at 2.2 angstrom resolution (1988) J Mol Biol 204, 191-204.
View information in the CaBP database derived from this reference

Babu, Y.S, Sack, J.S, Greenhough, T.J, Bugg, C.E, Means, A.R, Cook, W.J Three-dimensional structure of calmodulin (1985) Nature 315, 37-40.
View information in the CaBP database derived from this reference

Bachs, O., Agell, N., Carafoli, E. Calmodulin and calmodulin-binding proteins in the nucleus (1994) Cell Calcium 16, 289-296.
Summary: good review of biological function of calmodulin in the nucleus.
No information from this reference is currently stored in the database

Bagshaw, C.R, Kendrick-Jones, J. Characterization of homologous divalent metal ion binding sites of vertebrate and molluscan myosins using electro paramagnetic resonance spectroscopy (1979) J Mol Biol 130, 317-336.
No information from this reference is currently stored in the database

Baimbridge, K.G, Celio, M.R, Rogers, J.H Calcium-binding proteins in the nervous system (1992) Trends Neurosci 15, 303-308.
No information from this reference is currently stored in the database

Baldellon, C., Alattia, J.-R., Strub, M.-P., Pauls, T., Berchtold, M.W, Cave, A., Padilla, A. 15N NMR relaxation studies of calcium-loaded parvalbumin show tight dynamics compared to those of other EF-hand proteins (1998) Biochemistry 37, 9964-9975.
No information from this reference is currently stored in the database

Baldellon, C., Padilla, A., Cave, A. Kinetics of amide proton exchange in parvalbumin studied by (1)H 2-D NMR. A comparison of the calcium and magnesium loaded forms (1992) Biochimie 74, 837-844.
No information from this reference is currently stored in the database

Balmain, N. Calbindin D(9k): A vitamin D dependent, calcium-binding protein in mineralized tissues (1991) Clin Orthop 265, 265-276.
Summary: A summary of what is known about the role of calbindin in bones and teeth..
No information from this reference is currently stored in the database

Ban, C., Ramakrishnan, B., Ling, K.Y, Kung, C., Quiocho, F.A Structure of recombinant Paramecium tetraurella calmodulin at 1.68 angstrom resolution (1994) Acta Crystall D 50, 50-63.
View information in the CaBP database derived from this reference

Barbato, G., Ikura, M., Kay, L.E, Pastor, R.W, Bax, A. Backbone dynamics of calmodulin studied by (15)N relaxation using inverse deteced two-dimensional NMR spectroscopy: the central helix is flexible (1992) Biochemistry 31, 5269-5278.
No information from this reference is currently stored in the database

Barger, S.W, Van Eldik, L.J S100 beta stimulates calcium fluxes in glial and neuronal cells (1992) J Biol Chem 267, 9689-9694.
No information from this reference is currently stored in the database

Barger, S.W, Wolchok, S.R, Van Eldik, L.J Disulfide-linked S100B dimers and signal transduction (1992) Biochim Biophys Acta 1160, 105-112.
No information from this reference is currently stored in the database

Barraclough, R. "S100A4" in Guidebook to the Calcium-Binding Proteins, M.R.Celio, T.Pauls, B.Schwaller, eds. (1996) Oxford University Press, Oxford. 139-141.
View information in the CaBP database derived from this reference

Barraclough, R., Rudland, P.S The S100-related calcium-binding protein, p9Ka, and metastasis in rodent and human mammary cells (1994) Eur J Cancer 30A, 1570-1576.
Summary: Describes the use of an antibody specifc for p9Ka to look at the tissue distribution and subcellular localization of this protein..
View information in the CaBP database derived from this reference

Baudier, J., Bergeret, E., Bertacchi, N., Weintraub, H., Gagnon, J., Garin, J. Interactions of myogenic bHLH transcription factors with calcium-binding calmodulin and S100a (alpha alpha) proteins (1995) Biochemistry 34, 7834-7846.
View information in the CaBP database derived from this reference

Baudier, J., Delphin, C., Grunwald, D., Khochbin, S., Lawrence, J.J Characterization of the tumor suppressor protein p53 as a protein kinase C substrate and a S100b-binding protein (1992) Proc Natl Acad Sci USA 89, 11627-11631.
View information in the CaBP database derived from this reference

Baudier, J., Glasser, N., Gerard, D. Ions binding to S100 proteins (1986) J Biol Chem 261, 8192-8203.
No information from this reference is currently stored in the database

Baudier, J., Labourdette, G., Gerard, D. Rat brain S100b protein: purification, characterization, and ion binding properties. A comparison with bovine S100b protein (1985) J Neurochem 44, 76-84.
View information in the CaBP database derived from this reference

Baum, P., Furlong, C., Byers, B. Yeast gene required for spindle pole body duplication: homology of its product with Ca2+-binding proteins (1986) Proc Natl Acad Sci USA 83, 5512-5516.
No information from this reference is currently stored in the database

Baum, P., Yip, C., Goetsch, L., Byers, B. A yeast gene essential for regulation of spindle pole duplication (1988) Mol Cell Biol 8, 5386-5397.
No information from this reference is currently stored in the database

Bax, A., Clore, G.M, Driscoll, P.C, Gronenborn, A.M, Ikura, M., Kay, L.E Practical aspects of proton-carbon-carbon-proton three-dimensional correlation spectroscopy of 13C-labeled proteins (1990) J Magn Reson 87, 620-627.
No information from this reference is currently stored in the database

Bax, A., Clore, G.M, Gronenborn, A.M 1H-1H correlation via isotropic mixing of 13C magnetization, a new three-dimensional approach for assigning 1H and 13C spectra of 13C-enriched proteins (1990) J Magn Reson 88, 425-431.
No information from this reference is currently stored in the database

Bax, A., Grzesiek, S. Methodological advances in protein NMR (1993) Acc Chem Res 26, 131-138.
No information from this reference is currently stored in the database

Bax, A., Max, D., Zax, D. Long-range 13C-13C J. couplings in a 20-kDa protein-peptide complex (1992) J Am Chem Soc 114, 6923-6925.
No information from this reference is currently stored in the database

Baxevanis, A.D, Landsman, D. . Histone and histone fold sequences and structures: a database (1997) Nucleic Acids Res 25, 272-273.
No information from this reference is currently stored in the database

Bayley, P.M, Findlay, W.A, Martin, S.R Target recognition by calmodulin: Dissecting the kinetics and affinity of interaction using short peptide sequences (1996) Protein Sci 5, 1215-1228.
No information from this reference is currently stored in the database

Bazzi, M.D, Nelsestuen, G.L Protein kinase C and annexins: unusual calcium response elements in the cell (1993) Cell Signal 5, 357-365.
No information from this reference is currently stored in the database

Becker, T., Gerke, V., Kube, E., Weber, K. S100P, a novel Ca2+-binding protein from human placenta: cDNA cloning, recombinant protein expression and Ca2+ binding properties (1992) Eur J Biochem 207, 541-547.
View information in the CaBP database derived from this reference

Beckingham, K. Use of site-directed mutations in the individual Ca2+-binding sites of calmodulin to examine Ca2+-induced conformational changes (1991) J Biol Chem 266, 6027-6030.
No information from this reference is currently stored in the database

Belhadri, A. Presence of centrin in the human parasite Giardia: A further indication of its ubiquity in eukaryotes (1995) Biochem Biophys Res Comm 214, 597-601.
No information from this reference is currently stored in the database

Bentrop, D., Bertini, I., Cremonimi, M.A, Forsen, S., Luchinat, C., Malmendal, A. Solution structure of the paramagnetic complex of the N-terminal domain of calmodulin with two Ce3+ ions by (1)H NMR (1997) Biochemistry 36, 11605-11618.
View information in the CaBP database derived from this reference

Berchtold, M.W Evolution of EF-hand calcium modulated proteins. V. The genes encoding EF-hand proteins are not clustered in mammalian genomes (1993) J Mol Evol 36, 489-496.
No information from this reference is currently stored in the database

Bhardwaj, R.S, Zotz, C. ., Zwaldo-Klarwasser, G. ., Roth, J. ., Goebeler, M. ., Mahnke, K. ., Falk, M. ., Meinardus-Hager, G., Sorg, C. The calcium-binding proteins MRP8 and MRP14 form a membrane-associated heterodimer in a subset of monocytes/macrophages present in acute but absent in chronic inflammatory lesions (1992) Eur J Immunol 22, 1891-1897.
No information from this reference is currently stored in the database

Biamonti, C., Rios, C.B, Lyons, B.A, Montelione, G.T Multi-dimensional NMR experiments & analysis techniques for determining homo- and heteronuclear scalar coupling constants in proteins and nucleic acids (1994) Adv Biophys Chem 4, 51-120.
No information from this reference is currently stored in the database

Biekofsky, R.R, Martin, S.R, Browne, J.P, Bayley, P.M, Feeney, J. Ca2+ coordination to backbone carbonyl oxygen atoms in calmodulin and other EF-hand proteins: 15N chemical shifts as probes for monitoring individual-site ca2+ coordination (1998) Biochemistry 37, 7617-7629.
Summary: Investigates the use of the backbone (15)N chemical shift of the residue in position 8 (canonical loops) or 10 (pseudo loops) as a probe for metal ion occupancy.
No information from this reference is currently stored in the database

Billeter, M., Braun, W., Wuthrich, K. Sequential resonance assignments in protein 1H nuclear magnetic resonance spectra - computation of sterically allowed proton-proton distances and statistical analysis of proton-proton distances in single crystal protein conformations (1982) J Mol Biol 155, 321-346.
No information from this reference is currently stored in the database

Blanchard, H., Grochulski, P., Li, Y., Arthur, S.C, Davies, P.L, Elce, J.S, Cygler, M. Structure of a calpain Ca2+-binding domain reveals a novel EF-hand and Ca2+-induced conformational changes (1997) Nat Struct Biol 4, 532-538.
Summary: The paper for PDB entries 1AJ5 and 1DV1. It presents the structures of apo and calcium-loaded domain VI of calpain, and a preliminary analysis of the calcium-induced conformational changes, whicha re unlike any of the previously described conformational responses to calcium-binding..
View information in the CaBP database derived from this reference

Blanchard, H., Li, Y., Cygler, M., Kay, C.M, Arthur, J.SC., Davies, P.L, Elce, J.S Ca2+-binding domain VI of rat calpain is a homodimer in solution: hydrodynamic, crystallization and preliminary X-ray diffraction studies (1996) Protein Sci 5, 533-537.
Summary: The initial report of crystallization of rat calpain domain VI. The paper includes studies that show this domain to form homodimers in solution.
No information from this reference is currently stored in the database

Blancuzzi, Y., Padilla, A., Parello, J., Cave, A. Symmetrical rearrangement of the cation-binding sites of parvalbumin upon Ca(2+)/Mg(2+) exchange. A study by (1)H 2D NMR (1993) Biochemistry 32, 1302-1309.
No information from this reference is currently stored in the database

Blum, J.K, Berchtold, M.W Calmodulin-like effect of oncomodulin on cell prolifration (1994) J Cell Physiol 160, 455-462.
No information from this reference is currently stored in the database

Blumenthal, D.K, Krebs, E.G Preparation and properties of the calmodulin-binding domain of skeletal muscle myosin light chain knase (1987) Methods Enzymol 139, 115-126.
No information from this reference is currently stored in the database

Blumenthal, D.K, Takio, K. ., Edelman, A.M, Charbonneau, H. ., Titani, K. ., Walsh, K.A, Krebs, E.G Identification of the calmodulin-binding domain of skeletal muscle myosin light chain kinase (1985) Proc Natl Acad Sci USA 82, 3187-3191.
No information from this reference is currently stored in the database

Blundell, T.L, Sibanda, B.L, Sternberg, M.JE., Thornton, J.M Knowledge-based prediction of protein strucutres and the design of novel molecules (1987) Nature 326, 347-352.
No information from this reference is currently stored in the database

Bootman, M.D, Berridge, M.J The elemental principles of calcium signaling (1995) Cell 83, 675-678.
Summary: This minireview describes the fundamental units of a calcium signal in various systems and postulates on the roles of the complex types of calcium signals in biology.
No information from this reference is currently stored in the database

Borgias, B.A, James, T.L COMATOSE, a method for constrained refinement of macromolecular structure based on two-dimensional nuclear overhauser effect spectra (1988) J Magn Reson 79, 493-512.
No information from this reference is currently stored in the database

Borgias, B.A, James, T.L MARDIGRAS: A procedure for matrix analysis of relaxation for discerning geometry of an aqueous structure (1990) J Magn Reson 87, 475-487.
No information from this reference is currently stored in the database

Borgias, B.A, James, T.L Two-dimensional nuclear Overhauser effect: complete relaxation matrix analysis (1989) Methods Enzymol 176, 169-183.
No information from this reference is currently stored in the database

Bostrom, S.-L., Ljung, B., Mardh, S., Forsen, S., Thulin, E. Interaction of the antihypertensive drug felodipine with calmodulin (1981) Nature 292, 777-778.
No information from this reference is currently stored in the database

Boucher, W., Laue, E.D, Campbell-Burk, S., Domaille, P.J Four-dimensional heteronuclear triple-resonance NMR methods for the assignment of backbone nuclei in proteins (1992) J Am Chem Soc 114, 2262-2264.
No information from this reference is currently stored in the database

Bower, M.J, Cohen, F.E, Dunbrack, R.LN., Jr. Prediction of proteins side-chain rotamers from a backbone-dependent rotamer library: a new homology modeling tool (1997) J Mol Biol 267, 1268-1282.
No information from this reference is currently stored in the database

Brandt, P.W, George, S.E, Scachat, F. Calmodulin is intrinsically less effective that troponin C in activating skeletal muscle contraction (1994) FEBS Lett 353, 99-102.
View information in the CaBP database derived from this reference

Brodersen, D.E, Etzerodt, M., Celis, J.E, Thorgersen, H.C, Nyborg, J., Kjeldgaard, M. EF-hands at atomic resolution: the structure of human psoriasin (S100A7) solved by MAD phasing (1998) Structure 6, 477-489.
Summary: This paper presents the crystal structure of the S100A7 homodimer with two lanthanide ins bound and compares it to other structures of S100 proteins.
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Brodersen, D.E, Nyborg, J. ., Kjeldgaard, M. . Zinc-binding site of an S100 protein revealed. Two crystal structures of Ca2+-bound human psoriasin (S100A7) in the Zn2+-loaded and Zn2+-free states (1999) Biochemistry 38, 1695-1704.
View information in the CaBP database derived from this reference

Brodin, P., Drakenberg, T., Thulin, E., Forsen, S., Grundstrom, T. Selective proton labelling of amino acids in deuterated bovine calbindin D9k. A way to simplify (1)H-NMR spectra (1989) Protein Eng 2, 353-358.
No information from this reference is currently stored in the database

Brodin, P., Grundstrom, T., Hofmann, T., Drakenberg, T., Thulin, E., Forsen, S. Expression of bovine intenstinal calcium binding protein from a synthetic gene in Escherichia coli and characterization of the product (1986) Biochemistry 25, 5371-5377.
No information from this reference is currently stored in the database

Brodin, P., Johansson, C., Forsen, S., Drakenberg, T., Grundstrom, T. Functional properties of calbindin D9k mutants with exchanged Ca(2+) binding sites (1990) J Biol Chem 265, 11125-11130.
Summary: Three mutants were made: one with two site I binding loops (mutant A), one with two site II binding loops (mutant B), and one with the site I and site II loops exchanged (mutant C). All three mutants bind calcium-- mutant B has a decrease in affinity (with respect to wildtype) of about one order of magnitude, while mutants A and C have a decrease in affinity of about two orders of magnitude. Cooperativity of binding is lost in all three mutants..
No information from this reference is currently stored in the database

Bronner, F., Pansu, D., Stein, W.F An analysis of intestinal calcium transport across the rat intestine (1986) Am J Physiol 150G, 561-569.
View information in the CaBP database derived from this reference

Brooks, B.R, Bruccoleri, R.E, Olafson, B.D, States, D.J, Swaminathan, S. ., Karplus, M. . CHARMM: A program for macromolecular energy, minimization, and dynamics calculations (1983) J Comput Chem 4, 187-217.
No information from this reference is currently stored in the database

Brooks, C.L. Karplus, M. . Pettitt, B.M. eds. Proteins:A Theoretical Perspective of Synamics, Structure, and Thermodynamics (1988) John Wiley & Sons, New York.
No information from this reference is currently stored in the database

Brun, J.G, Jonsson, R. ., Haga, H.J Measurement of plasma calprotectin as an indicator of arthritis and disease activity in patients with inflammatory rheumatic diseases (1994) J Rheumatol 21, 733-738.
No information from this reference is currently stored in the database

Bruns, M.E, Kleeman, E., Bruns, D.E Vitamin D-dependent calcium-binding protein of mouse yolk sac (1986) J Biol Chem 261, 7485-7490.
No information from this reference is currently stored in the database

Bruns, M.E, Overpeck, J.G, Smith, G.C, Hirsch, G.N, Mills, S.E Vitamin D-dependent calcium binding protein in rat uterus: differential effects of estrogen, tamoxifen, progesterone and pregnancy on accumulation and cellular localization (1988) Endocrinology 122, 2371-2378.
Summary: A study of the localization of calbindin D9k in uterine tissues of pregnant rats and hormone-treated non-pregnant rats. Estrogen only partially mimcs the effects of pregnancy on calbindin distribution.
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Bryant, R.G The dynamics of water-protein interactions (1996) Annu Rev Biophys Biomol Struct 25, 29-53.
No information from this reference is currently stored in the database

Brzeska, H., Venyaminov, S., Grabarek, Z., Drabikowski, W. Comparative studies on thermostability of calmodulin, skeletal muscle troponin C and their tryptic fragments (1983) FEBS Lett 153, 169-173.
No information from this reference is currently stored in the database

Bullock, S., Hayward, C., Manson, J., Brock, D.JH., Raeburn, J.A Quantitative immunoassays for diagnosis and carrier detection in cystic fibrosis (1982) Clin Genet 21, 336-341.
View information in the CaBP database derived from this reference

Calabretta, B., Kaczmarek, L., Mars, W., Ochoa, D., Gibson, C., Hirschhorn, R., Baserga, R. Cell-cycle-specific genes differentially expressed in human leukemias (1985) Proc Natl Acad Sci USA 82, 4463-4467.
View information in the CaBP database derived from this reference

Calbretta, B., Venurelli, D., Kaczmarek, L., Narni, F., Talpaz, M., Anderson, B., Beran, M., Baserga, R. Altered expression of G1-specific genes in human malignant myeloid cell (1986) Proc Natl Acad Sci USA 83, 1495-1498.
No information from this reference is currently stored in the database

Campbell, A.P, Sykes, B.D Interaction of troponin I and troponin C: use of the two-dimensional nuclear magnetic resonance transferred nuclear Overhauser effect to determine the structure of teh inhibitory troponin I peptide when bound to skeletal troponin C (1991) J Mol Biol 222, 405-421.
No information from this reference is currently stored in the database

Carlstrom, G., Chazin, W.J Two-dimensional (1)H nuclear magnetic resonance studies of the half-saturated (Ca(2+))1 state of calbindin D9k: further implications for the molecular basis of cooperative Ca(2+) binding (1993) J Mol Biol 231, 415-430.
No information from this reference is currently stored in the database

Cave, A., Saint-Yves, A., Parello, J., Sward, M., Thulin, E., Lindman, B. NMR studies on parvalbumin phylogeny and ionic interactions (1982) Mol Cell Biochem 44, 161-172.
Summary: One of the original papers describing the spectroscopic identification of the secondary metal ion binding site found in some parvalbumins..
No information from this reference is currently stored in the database

Celio, M.R. Pauls, T. Schwaller, B. eds. Guidebook to the Calcium-Binding Proteins (1996) Oxford University Press, Oxford.
No information from this reference is currently stored in the database

Channon, J.Y, Leslie, C.C A calcium-dependent mechanism for associating a soluble arachidonoyl-hydrolyzing phospholipase A2 with membrane in the macrophage cell line RAW 264.7 (1990) J Biol Chem 265, 5409-5413.
No information from this reference is currently stored in the database

Chapman, E.R, Alexander, K., Vorherr, T., Carofoli, E., Storm, D.R Fluorescence energy transfer analysis of calmodulin-peptide complexes (1992) Biochemistry 31, 12819-12825.
No information from this reference is currently stored in the database

Charbonneau, H., Kuamr, S., Novack, J.P, Blumenthal, D.K, Griffin, P.R, Shabanowitz, J., Hunt, D.F, Beavo, J.A, Walsh, K.A Evidence for domain organization within the 61-kDa calmodulin-dependent cyclic nucleotide phosphodiesterase from bovine brain (1991) Biochemistry 30, 7931-7940.
View information in the CaBP database derived from this reference

Chard, P.S, Bleakman, D., Christakos, S., Fullmer, C.S, Miller, R.J Calcium buffering properties of calbindin D28k and parvalbumin in rat sensory neurones (1993) J Physiol 472, 341-357.
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Chattopadhyaya, R., Meador, W., Means, A., Quiocho, F. Calmodulin structure refined at 1.7 angstrom resolution (1992) J Mol Biol 228, 1177-1192.
View information in the CaBP database derived from this reference

Chazin, W.J New nuclear magnetic resonance structures and structural methodology (1991) Curr Opin Biotech 2, 520-525.
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Chazin, W.J Releasing the calcium trigger (1995) Nat Struct Biol 2, 707-710.
Summary: News and views article commenting on the structures of apo calmodulin and troponin C published in the same issue..
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Chazin, W.J, Kordel, J., Thulin, E., Hoffmann, T., Drakenberg, T., Forsen, S. Identification of an isoaspartyl linkage formed upon deamidation of bovine calbindin D9k and structural characterization by 2D 1H NMR (1989) Biochemistry 28, 8646-8653.
No information from this reference is currently stored in the database

Chazin, W.J, Rance, M., Wright, P.E Complete assignment of the 1H NMR magnetic resonance spectrum of french bean plastocyanin. Application of an integrated approach to spin system identification in proteins (1988) J Mol Biol 202, 603-622.
No information from this reference is currently stored in the database

Chen, C.-K., Hurley, J.B "Recoverin" in Guidebook to the Calcium-Binding Proteins, M.R.Celio, T.Pauls, B.Schwaller, eds. (1996) Oxford University Press, Oxford. 119-120.
Summary: A brief chapter summarizing the basic characteristics and properties of recoverin.
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Chen, C.-K., Inglese, J., Lefkowitz, R.J, Hurley, J.B Ca2+-dependent interaction of recoverin and rhodopsin kinase (1995) J Biol Chem 270, 18060-18066.
View information in the CaBP database derived from this reference

Cheney, R.E, Mooseker, M.S Unconventional myosins (1992) Curr Opin Cell Biol 4, 27-35.
Summary: Among other things, this review describes the myosins that use calmodulin for their light chains..
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Chin, D., Means, A.R Methionine to glutamine substitutions in the C-terminal domain of calmodulin impair the activation of three protein kinases (1996) J Biol Chem 271, 30465-30471.
Summary: Describes several single met to gln mutations in CaM and the effect of these mutations on CaMıs ability to activate CaMKIIa, smMLCK, and CaMKIV. All mutants were impaired in their ability to activate at least one of these targets..
View information in the CaBP database derived from this reference

Chothia, C., Gerstein, M. How far can sequences diverge (1997) Nature 385, 579-580.
Summary: A brief review of two recent protein engineering studies and a discussion of their implications for the amount of evolutionary divergence proteins can tolerate in their sequences.
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Chothis, C., Lesk, A.M The relation between the divergence of sequence and structure in proteins (1986) EMBO J 5, 823-826.
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Christakos, S., Gabrielides, C., Rhoten, W.B Vitamin D-dependent calcium binding proteins: chemistry, distribution, functional considerations, and molecular biology (1989) Endoc Rev 10, 3-26.
Summary: A very useful summary of information about the biology and function of calbindin D28k and calbindin D9k..
View information in the CaBP database derived from this reference

Clapham, D.E Calcium Signaling (1995) Cell 80, 259-268.
Summary: A review of the pathways and mechanisms of signal transduction involving calcium, including a section on calcium waves..
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Clapham, D.E, Sneyd, J. Intracellular calcium waves (1995) Adv Second Messenger Phosphoprotein Res 30, 1-24.
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Clementi, E., Meldolesi, J. The cross-talk between nitric ixude and Ca2+: a story with a complex past and a promising future (1997) Trends Pharmacol Sci 18, 266-269.
Summary: A brief review of the current knowledge about interaction of the Ca2+ and NO-cGMP signaling systems.
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Clipstone, N.A, Crabtree, G.R Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation (1992) Nature 357, 695-697.
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Clore, G.M, Bax, A., Driscoli, P.C, Wingfield, P.T, Gronenborn, A.M Assignment of the side-chain 1H and 13C resonances of interleukin-1 using double- and triple-resonance heteronuclear three-dimensional NMR spectroscopy (1990) Biochemistry 29, 8172-8184.
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Clore, G.M, Bax, A., Wingfield, P.T, Gronenborn, A.M Identification and localization of bound internal water in the solution structure of inter-leukin 1 by heteronuclear three-dimensional 1H rotating-frame Overhauser 15N- 1H multiple quantum coherence NMR spectroscopy (1990) Biochemistry 29, 5671-5676.
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Clore, G.M, Brunger, A.T, Karplus, M., Gronenborn, A.M Application of molecular dynamics with interproton distance restraints to three-dimensional protein structure determination. A model study of crambin (1986) J Mol Biol 191, 523-551.
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Clore, G.M, Gronenborn, A.M Structures of larger proteins in solution: three- and four-dimensional heteronuclear NMR spectroscopy (1991) Science 252, 1390-1399.
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Clore, G.M, Gronenborn, A.M Two-, three- and four-dimensional NMR methods for obtaining larger and more precise three-dimensional structures of proteins in solution (1991) Annu Rev Biophys Biophys Chem 20, 29-63.
No information from this reference is currently stored in the database

Coe, F.L, Nakagawa, Y., Asplin, J., Parks, J.H Role of nephrocalcin in inhibition of calcium oxalate crystallization and nephrolithiasis (1994) Miner Electrolyte Metab 20, 378-384.
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Colbran, R.J, Schworer, C.M, Hashimoto, Y., Fong, Y.-L., Rich, D.P, Smith, M.K, Soderling, T.R Calcium/calmodulin-dependent protein kinase II (1989) Biochem J 258, 313-325.
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Colbran, R.J, Soderling, T.R Calcium/calmodulin dependent protein kinase II (1990) Curr Topics Cell Reg 31, 181-221.
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Collins, J.H, Borysenko, C.W The 110,000-dalton actin- and calmodulin-binding protein from intestinal brush border is a myosin-like ATPase (1984) J Biol Chem 259, 14128-14135.
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Collins, K., Sellers, J.R, Matsudaira, P. Calmodulin dissociation regulates brush border myosin I (110 kD-calmodulin) mechanochemical activity in vitro (1990) J Cell Biol 110, 1137-1147.
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Cook, W.J, Jeffrey, L.C, Cox, J.A, Vijay-Kumar, S. Structure of a sarcoplasmic calcium-binding protein from amphioxus refined at 2.4 A resolution (1993) J Mol Biol 229, 461-471.
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Cook, W.J, Walter, L.J, Walter, M.R Drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex (1994) Biochemistry 33, 15259-15256.
View information in the CaBP database derived from this reference

Cormier, M.J, Charbonneau, H., Jarrett, H.W Plant and fungal calmodulin: Ca2+-dependent regulation of plant NAD kinase (1981) Cell Calcium 2, 313-331.
View information in the CaBP database derived from this reference

Cotton, F.A, Hazen, E.E, Legg, M.J Staphyloccocal nuclease: proposed mechanism of action based on structure of enzyme-thymidine 3ı,5ı-bisphosphate-calcium ion complex at 1.5-angstrom resolution (1979) Proc Natl Acad Sci USA 76, 2551-2555.
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Cox, J.A, Milos, M., MacManus, J.P Calcium- and magnesium-binding properties of oncomodulin (1990) J Biol Chem 265, 6633-6637.
View information in the CaBP database derived from this reference

Cox, J.A, Stein, E.A Characterization of a new sarcoplasmic calcium-binding protein with magnesium-induced cooperativity in the binding of calcium (1981) Biochemistry 20, 5430-5436.
Summary: The first report of the basic characteristics of sarcoplasmic calcium-binding protein from Nereis divisicolor, inclusing its calcium and magnesium binding properties.
View information in the CaBP database derived from this reference

Craig, T.A, Watterson, D.M, Prendergast, F.G, Haiech, J., Roberts, D.M Site-specific mutagenesis of the a-helices of calmodulin (1987) J Biol Chem 262, 3278-3284.
No information from this reference is currently stored in the database

Craven, C.J, Whitehead, B., Jones, S.KA., Thulin, E., Blackburn, G.M, Waltho, J.P Complexes formed between calmodulin and the antagonists J-8 and TFP in solution (1996) Biochemistry 35, 10287-10299.
No information from this reference is currently stored in the database

Crawford, C., Brown, N.R, Willis, A.C Studies of the active site of m-calpain and the interaction with calpastatin (1993) Biochem J 296, 135-142.
No information from this reference is currently stored in the database

Crivici, A., Ikura, M. Molecular and structural basis of target recognition by calmodulin (1995) Annu Rev Biophys Biomol Struct 24, 85-116.
View information in the CaBP database derived from this reference

Croall, D.E, Demartino, G.N Calcium-activated neutral protease (calpain) system: structure, function, and regulation (1991) Physiol Rev 71, 813-847.
Summary: An extensive and careful review..
View information in the CaBP database derived from this reference

da Silva, A.CR., Reinach, F.C Calcium binding induces conformational changes in muscle regulatory proteins (1991) Trends Biochem Sci 16, 53-57.
No information from this reference is currently stored in the database

Dalgarno, D.C, Klevit, R.E, Levine, B.A, Scott, G.MM., Williams, R.JP., Gergely, J., Grabarek, Z., Leavis, P.C, Grand, R.JA., Drabikowski, W. The nature of the trifluoperazine binding sites on calmodulin and troponin C (1984) Biochim Biophys Acta 791, 164-172.
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Dasgupta, M., Honeycutt, T., Blumenthal, D.K The gamma-subunit of skeletal muscle phosphorylase kinase contains two noncontiguous domains that act in concert to bind calmodulin (1989) J Biol Chem 264, 17156-17163.
View information in the CaBP database derived from this reference

Davies, B.R, Davies, M.PA., Gibbs, F.EM., Barraclough, R., Rudland, P.S Induction of the metastatic phenotype by transfection of a benign rat memmary epithelial cell line with the gene for p9Ka, a rat calcium-binding protein, but not with the oncogene EJ-ras-1 (1993) Oncogene 8, 999-1008.
No information from this reference is currently stored in the database

de Beer, T., Carter, R.E, Lobel-Rice, K.E, Sorkin, A., Overduin, M. Structure and Asn-Pro-Phe binding pocket of the Eps15 homology domain (1998) Science 281, 1357-1360.
No information from this reference is currently stored in the database

Declercq, J.-P., Tinant, B., Parello, J. X-ray structure of a new crystal form of pike 4.10 beta parvalbumin (1996) Acta Crystall D 52, 165-169.
Summary: The reference for pdb entry 1PVB.
View information in the CaBP database derived from this reference

Declercq, J.-P., Tinant, B., Parello, J., Etienne, G. Crystal structure determination and refinement of pike 4.10 parvalbumin (minor component from Esox lucius) (1988) J Mol Biol 202, 349-353.
No information from this reference is currently stored in the database

Declercq, J.-P., Tinant, B., Parello, J., Rambaud, J. Ionic interactions with parvalbumins: crystal structure determination of pike 4.10 parvalbumin in four different ionic environments (1991) J Mol Biol 220, 1017-1039.
View information in the CaBP database derived from this reference

Delabie, J. ., de Wolf-Peeters, C. ., van den Oord, J.J, Desmet, V.J Differential expression of the calcium-binding proteins MRP8 and MRP14 in granulomatous conditions: an immunohistochemical study (1990) Clin Exp Immunol 81, 123-126.
No information from this reference is currently stored in the database

Dell'Angelica, E.C, Schleicher, C.H, Santome, J.A Primary structure and binding properties of calgranulin C, a novel S100-like calcium-binding protein from pig granulocytes (1994) J Biol Chem 269, 28929-28936.
View information in the CaBP database derived from this reference

Delorme, A.C, Danan, J.L, Acker, M.G, Ripoche, M.A, Mathieu, H. In rat uterus 17 beta-estradiol stimulates a calcium-binding protein similar to the duodenal vitamin D-dependent calcium-binding protein (1983) Endocrinology 113, 1340-1347.
No information from this reference is currently stored in the database

Denisov, V.P, Halle, B. Direct observation of calcium-coordinated water in calbindin D9k by nuclear magnetic relaxation dispersion (1995) J Am Chem Soc 117, 8456-8465.
No information from this reference is currently stored in the database

Dennis, E.A Diversity of group types, regulation, and function of phospholipase A2 (1994) J Biol Chem 269, 13057-13060.
Summary: A concise and useful minireview.
No information from this reference is currently stored in the database

Dodson, E.J, Davies, G.J, Lamzin, V.S, Murshudov, G.N, WIlson, K.S Validation tools: can they indicate the information content of macromolecular crystal structures? (1998) Structure 6, 685-690.
No information from this reference is currently stored in the database

Doerks, T., Bairoch, A., Bork, P. Protein annotation: detective work for function prediction (1998) Trends Genet 14, 248-250.
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Donato, R. . Perspectives in S-100 protein biology (1991) Cell Calcium 12, 713-726.
No information from this reference is currently stored in the database

Donato, R. Calcium-independent, pH-regulated effects of S-100 proteins on assembly-disassembly of brain microtubule protein in vitro (1988) J Biol Chem 263, 106-110.
View information in the CaBP database derived from this reference

Donato, R., Isobe, T., Okuyama, T. S-100 proteins and microtubules: analysis of the effects of rat brain S-100 (S-100b) and ox brain S100a0, S-100a and S-100b on microtubule assembly-disassembly (1985) FEBS Lett 186, 65-69.
View information in the CaBP database derived from this reference

Dorin, J.R, Emslie, E., van Heyningen, V. Related calcium-binding proteins map to the same subregion of chromosome 1q and to an extended region of synteny on mouse chromosome 3 (1990) Genomics 8, 420-426.
View information in the CaBP database derived from this reference

Drakenberg, T., Sward, M., Cave, A., Parello, J. Metal-ion binding to parvalbumin (1985) Biochem J 227, 711-717.
No information from this reference is currently stored in the database

Driscoll, P.C, Clore, G.M, Dominique, M., Wingfield, P.T, Gronenborn, A. Complete resonance assignment for the polypeptide backbone of Interleukin 1 using three-dimensional NMR spectroscopy (1990) Biochemistry 29, 3542-3556.
No information from this reference is currently stored in the database

Drohat, A.C, Amburgey, J.C, Abildgaard, F., Starich, M.R, Baldisseri, D., Weber, D.J Solution structure of rat apo-S100B(bb) as determined by NMR spectroscopy (1996) Biochemistry 35, 11577-1588.
View information in the CaBP database derived from this reference

Drohat, A.C, Baldisseri, D.M, Rustandi, R.R, Weber, D.J Solution structure of calcium-bound rat S100B(bb) as determined by nuclear magnetic resonance spectroscopy (1998) Biochemistry 37, 2729-2740.
Summary: The paper for PDB entry 1QLK..
View information in the CaBP database derived from this reference

Duncan, A.MV., Higgins, J., Dunn, R.J, Allore, R., Marks, A. Refined sublocalization of the human gene encoding the b subunit of S100 protein (S100b) and confirmation of a subtle t(9:21) translocation using in situ hybridization (1989) Cytogenet Cell Genet 50, 234-235.
View information in the CaBP database derived from this reference

Durussel, I., Luan-Rilliet, Y., Petrova, T., Takagi, T., Cox, J.A Cation binding and conformation of tryptic fragments of Nereis sarcoplasmic calcium-binding protein: Calcium-induced homo- and heterodimerization (1993) Biochemistry 32, 2394-2400.
No information from this reference is currently stored in the database

Durussel, I., Pauls, T.L, Cox, J.A, Berchtold, M.W Chimeras of parvalbumin and oncomodulin involving exchange of the complete CD site show that the Ca2+/Mg2+ specificity is an intrinsic property of the site (1996) Eur J Biochem 242, 256-263.
No information from this reference is currently stored in the database

Eberhard, M., Erne, P. Calcium and magnesium binding to rat parvalbumin (1994) Eur J Biochem 222, 21-26.
No information from this reference is currently stored in the database

Ebralidze, A., Tulchimsky, E., Grigorian, M., Afanasyeva, A., Senin, V., Revazova, E., Lukanidin, E. Isolation and characterization of a gene specifically expressed in different metastatic cells and whose deduced gene product has a high degree of homology to a Ca++-binding protein family (1989) Genes and Develop 3, 1086-1093.
View information in the CaBP database derived from this reference

Edgeworth, J. ., Freemont, P. ., Hogg, N. . Ionomycin-regulated phosphorylation of the myeloid calcium-binding protein p14 (1989) Nature 342, 189-192.
No information from this reference is currently stored in the database

Edgeworth, J., Gorman, M., Bennet, R., Freemont, P., Hogg, N. Identification of p8,14, as a highly abundant heterodimeric calcium binding protein complex of myeloid cells (1991) J Biol Chem 266, 7706-7713.
View information in the CaBP database derived from this reference

Edman, C.F, George, S.E, Means, A.R, Schulman, H., Yaswen, P. Selective activation and inhibition of calmodulin-dependent enzymes by a calmodulin-like protein found in human epithelial cells (1994) Eur J Biochem 226, 725-730.
Summary: Calmodulin-like protein was found to activate CaMKII, but not calcineurin, nitric oxide synthase, or smMLCK. In fact, it is a competitive inhibitor of smMLCK activation by calmodulin. Based on their data, the authors propose some interesting speculations about the functional role of calmodulin-like proteins..
View information in the CaBP database derived from this reference

Ehrhardt, M.R, Urbauer, J.L, Wand, A.J The energetics and dynamics of molecular recognition by calmodulin (1995) Biochemistry 34, 2731-2738.
No information from this reference is currently stored in the database

Engelborghs, Y., Mertens, K., Willaert, K., Luan-Rilliet, Y., Cox, J.A Kinetics of conformational changes in Nereis sarcoplasmic calcium-bidning protein upon binding of divalent ions (1990) J Biol Chem 265, 18809-18815.
No information from this reference is currently stored in the database

Englekamp, D. ., Schafer, B.W, Mattei, M.G, Erne, P. ., Heizmann, C.W Six S100 genes are clustered on human chromosome 1q21: identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E. (1993) Proc Natl Acad Sci USA 90, 6547-6551.
No information from this reference is currently stored in the database

Espreafico, E.M, Cheney, R.E, Matteoli, M., Nascimento, A.AC., DeCamilli, P.V, Larson, R.E, Mooseker, M.S Primary structure and cellular localization of chicken brain myosin-V (p190), an unconventional myosin with calmodulin light chains (1992) J Cell Biol 119, 1541-1557.
Summary: Reference about calmodulin binding to unconventional mmyosins via an IQ-motif.
No information from this reference is currently stored in the database

Evenas, J., Thulin, E., Malmendal, A., Forsen, S., Carlstrom, G. NMR studies of the E140Q mutant of the carboxy-terminal domain of calmodulin reveal global conformational exchange in the Ca2+-saturated state (1997) Biochemistry 36, 3448-3457.
Summary: This is the most careful study to date on the effects of mutating the bidentate Glu Ca2+ ligand in a sensor EF-hand protein. The authors conclude that this mutation causes the Ca2+-loaded state to be 60% in the open conformation and 40% in the closed conformation.
No information from this reference is currently stored in the database

Falke, J.J, Drake, S.K, Hazard, A.L, Peersen, O.B Molecular tuning of ion binding to calcium signaling proteins (1994) Quart Rev Biophys 27, 219-290.
No information from this reference is currently stored in the database

Fano, G., Angelella, P., Mariggio, D., Aisa, M.C, Giambanco, I., Donato, R. S-100a0 protein stimulates the basal (Mg2+-activated) adenylate cyclase activity associated with skeletal muscle membranes (1989) FEBS Lett 248, 9-12.
View information in the CaBP database derived from this reference

Fano, G., Marsili, V., Angelella, P., Aisa, M.C, Giambanco, I., Donato, R. S100a0 protein stimulates Ca2+-induced Ca2+ release from isolated sarcoplasmic reticulum vesicles (1989) FEBS Lett 255, 381-384.
View information in the CaBP database derived from this reference

Farah, C.S, Miyamoto, C.A, Ramos, C.HI., da Silva, A.CR., Quaggio, R.B, Fujimori, K., Smilie, L.B, Reinach, F.C Structural and regulatory functions of the NH2- and COOH-terminal regions of skeletal muscle troponin I (1994) J Biol Chem 269, 5230-5240.
No information from this reference is currently stored in the database

Farah, C.S, Reinach, F.C The troponin complex and regulation of muscle contraction (1995) FASEB J 9, 755-767.
No information from this reference is currently stored in the database

Farnsworth, C.L, Freshney, N.W, Rosen, L.B, Ghosh, A., Greenberg, M.E, Feig, L.A Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF (1995) Nature 376, 524-527.
Summary: Ras-GRF, a form of Ras thought to be neuron-specifc, is activated by Ca2+ influx. this seems to be mediated by ca2+-dependent binding of CaM to Ras-GRF. The binding of CaM requires an intact IQ motif. However, this IQ motif in Ras-GRF is not exactly like the consensus sequence..
No information from this reference is currently stored in the database

Feher, J.J Facilitated calcium diffusion by intestinal calcium-binding protein (1983) Am J Physiol 244C, 303-307.
View information in the CaBP database derived from this reference

Ferrari, S., Calabretta, B., deRies, J.K, Battin, R., Ghezzo, F., Lauret, E., Griffin, C., Emanuel, B., Gurrieri, F., Baserga, R. Structural and functional analysis of a growth-regulated gene, the human calcyclin (1987) J Biol Chem 262, 8325-8332.
No information from this reference is currently stored in the database

Filipek, A. ., Kuznicki, J. . Molecular cloning and expression of a mouse brain cDNA encoding a novel protein target of calcyclin (1998) J Neurochem 70, 1793-1798.
No information from this reference is currently stored in the database

Filipek, A. ., Wodja, U. ., Lesniak, W. . Interaction of calcyclin and its cyanogen bromide fragments with annexin II and glyceraldehyde 3-phosphate dehydrogenase (1995) Int J Biochem Cell Biol 27, 1123-1131.
No information from this reference is currently stored in the database

Filipek, A. ., Wojda, U. . p30, a novel protein target of mouse calcyclin (S100A6) (1996) Biochem J 320, 585-587.
No information from this reference is currently stored in the database

Filipek, A., Kuznicki, J. Calcyclin-- from basic research to clinical implications (1993) Acta Biochim Pol 40, 321-327.
View information in the CaBP database derived from this reference

Filipek, A., Puzianowska, M., Cieslak, B., Kuznicki, J. Calcyclin--Ca2+-binding protein homologous to glial S-100 beta is present in neurones (1993) Neuroreport 4, 383-386.
View information in the CaBP database derived from this reference

Findlay, W.A, Martin, S.M, Beckingham, K., Bayley, P.M Recovery of native structure by calcium binding site mutants of calmodulin upon binding of sk-MLCK target peptides (1995) Biochemistry 34, 2087-2094.
No information from this reference is currently stored in the database

Findlay, W.A, Sonnichsen, F.D, Sykes, B.D Solution structure of Tr1C fragment of skeletal muscle troponin C (1994) J Biol Chem 223, 601-606.
View information in the CaBP database derived from this reference

Finn, B.E, Evenas, J., Crakenberg, T., Waltho, J.P, Thulin, E., Forsen, S. Calcium-induced structural changes and domain autonomy in calmodulin (1995) Nat Struct Biol 2, 777-783.
View information in the CaBP database derived from this reference

Finn, B.E, Forsen, S. The evolving model of calmodulin structure, function and activation (1995) Structure 3, 7-11.
Summary: a minireview.
No information from this reference is currently stored in the database

Finn, B.E, Kordel, J., Thulin, E., Sellers, P., Forsen, S. Dissection of calbindin D9k into two Ca2+-binding subdomains by a combination of mutagenesis and chemical cleavage (1992) FEBS Lett 298, 211-214.
No information from this reference is currently stored in the database

Fischer, R., Koller, M., Flura, M., Mathews, S., Strehler-Page, M.-A., Krebs, J., Penniston, J.T, Carafoli, E., Strehler, E.E Multiple divergent mRNAs code for a single human calmodulin (1988) J Biol Chem 263, 17055-17062.
Summary: Reports the identification and characterization of the third gene for calmodulin in humans. This gene codes for an identical protein as the other two genes, but has an unusually divergent nucleotide sequence and quite different codon usage.
View information in the CaBP database derived from this reference

Fisher, P.J, Prendergast, F.G, Ehrhardt, M.R, Urbauer, J.L, Wand, A.J, Sedarous, S.S, McCormick, D.J, Buckley, P.J Calmodulin interacts with amphiphillic peptides composed of all D-amino acids (1994) Nature 368, 651-653.
Summary: An interesting study in which calmodulin is found to bind to D-peptides, although with a higher off-rate than to L-peptides.
No information from this reference is currently stored in the database

Flaherty, K.M, Zozulya, S., Stryer, L., McKay, D.B Three-dimensional structure of recoverin, a calcium sensor in vision (1993) Cell 75, 709-716.
View information in the CaBP database derived from this reference

Foguel, D., Suarez, M.C, Barbosa, C., Rodrigues, J.JN., Jr., Sorenso, M.M, Smillie, L.B, Silva, J.L Mimicry of the calcium-induced conformational state of troponin C by low temperature under pressure (1996) Proc Natl Acad Sci USA 93, 10642-10646.
No information from this reference is currently stored in the database

Forrest, S. Genetic algorithms: principles of natural selection applied to computation (1993) Science 261, 872-878.
No information from this reference is currently stored in the database

Forsen, S., Kordel, J., Grundstrom, T., Chazin, W.J The molecular anatomy of a calcium-binding protein (1993) Acc Chem Res 26, 7-14.
No information from this reference is currently stored in the database

Forsen, S., Linse, S. Cooperativity: over the Hill (1995) Trends Biochem Sci 20, 495-497.
Summary: A clear and useful discussion of how cooperativity should be defined.
No information from this reference is currently stored in the database

Freemont, P. ., Hogg, N. ., Edgeworth, J. . Sequence identity (1989) Nature 339, 516.
No information from this reference is currently stored in the database

Frishman, D., Heumann, K., Lesk, A., Mewes, H.-W. Comprehensive, comprehensible, distributed and intelligent databases: current status (1998) Bioinformatics 14, 551-561.
Summary: An interesting review of the current level of database integration, with a heavy emphasis on sequence databases.
No information from this reference is currently stored in the database

Fromherz, S., Szent-Gyorgyi, A.G Role of essential light chain EF hand domains in calcium binding and regulation of scallop myosin (1995) Proc Natl Acad Sci USA 92, 7652-7656.
No information from this reference is currently stored in the database

Fruman, D.A, Pai, S.Y, Burakoff, S.J, Bierer, B.E Characterization of a mutant calcineurin A alpha gene expressed by EL4 lymphoma cell (1995) Mol Cell Biol 15, 3857-3863.
No information from this reference is currently stored in the database

Fullmer, C.S, Wasserman, R.H The amino acid sequence of bovine intestinal calcium-binding protein (1981) J Biol Chem 256, 5669-5674.
Summary: The first report of the sequence of calbindin D9k, done at the amino acid level..
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Gagne, S., Tsuda, S., Li, M., Smillie, L., Sykes, B. Structures of the troponin C regulatory domains in the apo and calcium-saturated states (1995) Nat Struct Biol 2, 784-789.
View information in the CaBP database derived from this reference

Gagne, S.M, Li, M.X, Sykes, B.D Mechanism of direct coupling between binding and induced structural change in regulatory calcium binding proteins (1997) Biochemistry 36, 4386-4392.
View information in the CaBP database derived from this reference

Galperin, M.Y, Brenner, S.E Using metabolic pathway databases for functional annotation (1998) Trends Genet 14, 332-333.
No information from this reference is currently stored in the database

Gangola, P., Pant, H.C Temperature dependent conformational changes in calmodulin (1983) Biochem Biophys Res Comm 111, 301-305.
No information from this reference is currently stored in the database

Gao, Z.H, Krebs, J., VanBerkum, M.FA., Tang, W.-J., Maune, J.F, Means, A.R, Stull, J.T, Beckingham, K. Activation of four enzymes by two series of calmodulin mutants with point mutations in individual Ca(2+) binding sites (1993) J Biol Chem 268, 20096-20104.
Summary: A study of the ability of CaM mutants in which one of the bidentate Glu ligands has been replaced with Gln or Lys to activate smMLCK, skMLCK, adenyl cyclase, and plasma membrane Ca2+-ATPase.
No information from this reference is currently stored in the database

Garrels, J.I YPD-- A database for proteins of Saccharomyces cerevisiae (1996) Nucleic Acids Res 24, 46-49.
No information from this reference is currently stored in the database

Gellman, S. On the role of methionine residues in the sequence-independent recognition of nonpolar protein surfaces (1991) Biochemistry 30, 6633-6636.
No information from this reference is currently stored in the database

Gendler, S., Cohen, E., Craston, A., Duhig, T., Johnstone, G., Barnes, D. The locus of the polymorphic epithelial mucin (PEC) tumor antigen on chromosome 1q21 shows a high frequency of alteration in primary human breast tumors (1990) Int J Cancer 45, 431-435.
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George, S., Su, Z., Fan, D., Wang, S., Johnson, J.D The fourth EF-hand of calmodulin and its helix-loop-helix components: impact on calcium binding and enzyme activation (1996) Biochemistry 35, 8307-8313.
Summary: A study of calcium binding and enzyme activation properties of of several CaM/TnC chimeras and CaM mutants. All changes are in the C terminal domain of CaM. Changes in calcium affinity and off rate, cooperativity, and enzyme activation were observed for all mutants..
View information in the CaBP database derived from this reference

George, S.E, Su, Z., Fan, D., Means, A.R Calmodulin-cardiac troponin C chimeras (1993) J Biol Chem 268, 25213-25220.
No information from this reference is currently stored in the database

George, S.E, VanBerkum, M.FA., Ono, T., Cook, R., Hanley, R.M, Putkey, J.A, Means, A.R Chimeric calmodulin-cardiac troponin C proteins differentially activate calmodulin target enzymes (1990) J Biol Chem 265, 9228-9235.
View information in the CaBP database derived from this reference

Gerke, V. "S100A10" in Guidebook to the Calcium-Binding Proteins, (1996) Oxford University Press, Oxford. 149-151.
No information from this reference is currently stored in the database

Gerke, V. "S100P" in Guidebook to the Calcium-Binding Proteins, M.R.Celio, T.Pauls, B.Schwaller, eds. (1996) Oxford University Press, Oxford. 160.
Summary: A brief chapter summarizing the basic characteristics and properties of S100P.
View information in the CaBP database derived from this reference

Gerke, V., Weber, K. Calcium-dependent conformational changes in the 36-kDa subunit of intestinal protein I related to the cellular 36-kDa target of Rous sarcoma virus tyrosine kinase (1985) J Biol Chem 260, 1688-1695.
View information in the CaBP database derived from this reference

Ghosh, D. . A relational database of transcription factors (1990) Nucleic Acids Res 18, 1749-1756.
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Ghosh, D. . Status of the transcription factors database (TFD) (1993) Nucleic Acids Res 21, 3117-3118.
No information from this reference is currently stored in the database

Gibbs, F.EM., Barraclough, R., Platt-Higgins, A., Rudland, P., Wilkinson, M., Parry, E. Immunocytochemical distribution of the calcium-binding protein p9Ka in normal rat tissues: Variation in the cellular location in different tissues (1995) J Histochem Cytochem 42/43, 169-180.
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Giedroc, D.P, Puett, D., Ling, N., Staros, J.V Demonstration by covalent cross-linking of a specific interaction between b-endorphin and calmodulin (1983) J Biol Chem 258, 16-19.
No information from this reference is currently stored in the database

Gietzen, K., Wuthrich, A., Bader, H. R 24571: a new powerful inhibitor of red blood cell Ca(2+)-transport ATPase and of calmodulin-related functions (1981) Biochem Biophys Res Comm 101, 418-425.
No information from this reference is currently stored in the database

Gilli, R., Lafitte, D., Lopez, C., Kilhoffer, M.-C., Makarov, A., Briand, C., Haiech, J. Thermodynamic analysis of calcium and magnesium binding to calmodulin (1998) Biochemistry 37, 5450-5456.
Summary: Presents an analysis of the thermodynamics of Ca2+ and Mg2+ binding to CaM, and interprets the data under the preferenctial pathway (sequential) model of Ca2+ binding to CaM.
No information from this reference is currently stored in the database

Gilson, M.K, Given, J.A, Bush, B.L, McCammon, J.A The statistical-thermodynamic basis for a computation of binding affinities: a critical review (1997) Biophys J 72, 1047-1069.
No information from this reference is currently stored in the database

Gimona, M. ., Lando, Z. ., Dolginov, Y. ., Vanderkerckhove, J. ., Kobayashi, R. ., Sobieszek, A. ., Helfman, D.M Ca2+-dependent interaction of S100A2 with muscle and nonmuscle tropomyosin (1997) J Cell Sci 110, 611-621.
No information from this reference is currently stored in the database

Glazewski, S. ., Chen, C.-C., Silva, A. ., Fox, K. . Requirement for a-CaMKII in experience-dependent plasticity of the barrel cortex (1996) Science 268, 421-423.
View information in the CaBP database derived from this reference

Glenney, . Phospholipid-dependent Ca2+ binding by the 36-kDa tyrosine kinase substrate (calpactin) and its 33-kDa core (1986) J Biol Chem 261, 7247-7252.
View information in the CaBP database derived from this reference

Godzik, A. Counting and classifying possible protein folds (1997) Trends Biotech 15, 147-151.
No information from this reference is currently stored in the database

Godzik, A., Sander, C. Conservation of residue interactions in a family of Ca-binding proteins (1989) Protein Eng 2, 589-596.
No information from this reference is currently stored in the database

Goebeler, M. ., Roth, J. ., Burwinkel, F. ., Vollmer, E. ., Bocker, W. ., Sorg, C. . Expression and complex formation of S100-like proteins MRP8 and MRP14 by macrophages during renal allograft rejection (1994) Transplantation 58, 355-361.
No information from this reference is currently stored in the database

Golitsina, N.L, Kordowska, J. ., Wang, C.-W., Lehrer, S.S Ca2+-dependent binding of calcyclin to muscle tropomyosin (1996) Biochem Biophys Res Comm 220, 360-365.
No information from this reference is currently stored in the database

Goll, D.E, Thompson, V.F, Taylor, R.G, Zalewska, T. Is calpain activity regulate by membranes and autolysis or by calcium and calpastatin? (1992) BioEssays 14, 549-556.
Summary: A review arguing that the hypothesis that calpain is regulated by mebranes and autolysis is unable to explain all of the experimental data..
No information from this reference is currently stored in the database

Gopalakrishna, R., Anderson, W.B Ca(2+)-induced hydrophobic site on calmodulin: application for purification by phenyl-sepharose chromatography (1982) Biochem Biophys Res Comm 104, 830-836.
No information from this reference is currently stored in the database

Gopalakrishna, R., Anderson, W.B The effects of chemical modification of calmodulin on Ca(2+)-induced exposure of hydrophobic region. Separation of active and inactive forms of calmodulin (1985) Biochim Biophys Acta 844, 265-269.
No information from this reference is currently stored in the database

Gopalkrishna, R., Anderson, W.B The effects of chemical modification of calmodulin on Ca(2+)-induced exposure of a hydrophobic region. Separation of active and inactive forms of calmodulin (1985) Biochim Biophys Acta 844, 265-269.
No information from this reference is currently stored in the database

Gottesman, S. Genetics of proteolysis in Escherichia coli (1989) Annu Rev Genet 23, 163-198.
No information from this reference is currently stored in the database

Grabarek, Z., Tan, R.-Y., Wang, J., Tao, T., Gergely, J. Inhibition of mutant troponin C activity by an intra-domain disulphide bind (1990) Nature 345, 132-135.
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Grabarek, Z., Tao, T., Gergely, J. Molecular mechanism of troponin C function (1992) J Musc Res Cell Motil 13, 383-393.
No information from this reference is currently stored in the database

Greaser, M.L, Gergely, J. Reconstitution of troponin activity from three protein components (1971) J Biol Chem 246, 4226-4233.
No information from this reference is currently stored in the database

Griffin, W.S, Yeralan, O., Sheng, J.G, Boop, F.A, Mrak, R.E, Rovnaghi, C.R, Burnett, B.A, Feoktistova, A., Van Eldik, L.J Overexpression of the neurotrophic cytokine S100 beta in human temporal lobe epilepsy (1995) J Neurochem 65, 228-233.
View information in the CaBP database derived from this reference

Griffith, J.P, Kim, J.L, Kim, E.E, Sintchak, M.D, Thomson, J.A, Fitzgibbon, M.J, Fleming, M.A, Caron, P.R, Hsiao, K., Navia, M.A X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKB12-FK506 complex (1995) Cell 82, 507-522.
Summary: The paper for PDB entry 1TCO.
View information in the CaBP database derived from this reference

Groves, P., Finn, B.E, Kuznicki, J., Forsen, S. A model for target proteins binding to calcium-activated S100 dimers1 (1998) FEBS Lett 421, 175-179.
Summary: Presents a hypothesis about the mode by which S100 proteins interact with targets based on a mutant of calbindin D9k with an insertion in the linker loop.
No information from this reference is currently stored in the database

Groves, P., Linse, S., Thulin, E., Forsen, S. A calbindin D9k mutant containing a novel structural extension: (1)H nuclear magentic resonance studies (1997) Protein Sci 6, 323-330.
No information from this reference is currently stored in the database

Grzesiek, S., Bax, A. The importance of not saturating H2O in protein NMR. Application to sensitivity-enhancement and NOE measurements (1993) J Am Chem Soc 115, 12593-12594.
No information from this reference is currently stored in the database

Guerini, D. "Calcineurin" in Guidebook to the Calcium-Binding Proteins, M.R.Celio, T.Pauls, B.Schwaller, eds. (1996) Oxford University Press, Oxford. 30-32.
Summary: A brief review summarizing the basic properties and characteristics of calcineurin.
No information from this reference is currently stored in the database

Guerini, D. Calcineurin: Not just a simple protein phosphatase (1997) Biochem Biophys Res Comm 235, 271-275.
No information from this reference is currently stored in the database

Guerini, D., Krebs, J., Carafoli, E. Stimulation of the erythrocyte Ca(2+)-ATPase and of bovine brain cyclic nucleotide phosphodiesterase by chemically modified calmodulin (1987) Eur J Biochem 170, 35-42.
View information in the CaBP database derived from this reference

Guignard, F., Mauel, J., Markert, M. Identification and characterization of a novel human neutrophil protein related to the S100 family (1995) Biochem J 309, 395-401.
View information in the CaBP database derived from this reference

Guntert, P. ., Braun, W. ., Wuthrich, K. . Efficient computation of three-dimensional protein structures in solution from nuclear magnetic resonance data using the program DIANA and the supporting programs CALIBA, HABAS and GLOMSA (1991) J Mol Biol 217, 517-530.
No information from this reference is currently stored in the database

Hagens, G., Masouye, I., Augsburger, E., Hotz, R., Saurat, J.-H., Sigenthaler, G. Calcium-binding protein S100A7 and epidermal-type fatty acid-binding protein are associated in the cytosol of human keratinocytes (1999) Biochem J 339, 419-427.
View information in the CaBP database derived from this reference

Haiech, J., Derancourt, J., Pechere, J.-F., Demaille, J.G Magnesium and calcium binding to parvalbumins: Evidence for differences between parvalbumins and an explanation of their relaxing function (1979) Biochemistry 18, 2752-2758.
No information from this reference is currently stored in the database

Haiech, J., Kilhoffer, M.-C., Lukas, T.J, Craig, T.A, Roberts, D.M, Watterson, D.M Restoration of calcium binding activity of mutant clmodulins toward normal by presence of a calmodulin binding strucutre (1991) J Biol Chem 266, 3427-3431.
No information from this reference is currently stored in the database

Hanson, P.I, Schulman, H. Neuronal Ca(2+)/calmodulin-dependent protein kinases (1992) Annu Rev Biochemistry 61, 559-601.
No information from this reference is currently stored in the database

Harder, T., Gerke, V. The subcellular distribution of early endosomes is affected by the annexin II(2)p11(2) complex (1993) J Cell Biol 123, 1119-1132.
View information in the CaBP database derived from this reference

Harper, J.F, Sussman, M.R, Schaller, G.E, Putnam-Evans, C., Charbonneau, H., Harmon, A.C A calcium-dependent protein kinase with a regulatory domain similar to calmodulin (1993) Science 252, 951-954.
Summary: The first report of a clone of CDPK.
No information from this reference is currently stored in the database

Harris, E., Watterson, D.M, Thorner, J. Functional consequences in yeast of single-residue alterations in a consensus calmodulin (1994) J Cell Sci 107, 3235-3249.
No information from this reference is currently stored in the database

Harris, E., Yaswen, P., Thorner, J. Gain-of-function mutations in a human calmodulin-like protein identify residues critical for calmodulin action in yeast (1995) Mol Gen Genet 247, 137-147.
No information from this reference is currently stored in the database

Hart, K.W, Searls, D.B, Overton, G.C SORTEZ: A relational translator for NCBI's ASN.1 database (1994) CABIOS 10, 369-378.
No information from this reference is currently stored in the database

Havel, T.F, Kuntz, I.D, Crippen, G.M The effect of distance constraints on macromolecular conformation II. Simulation of experimental results and theoretical predictions (1979) Biopolymers 18, 73-82.
No information from this reference is currently stored in the database

Haverstick, D.M, Densmore, J.J, Gray, L.S Calmodulin regulation of Ca2+ entry in Jurkat T cells (1998) Cell Calcium 23, 361-367.
No information from this reference is currently stored in the database

Head, J.F "Squidulin" in Guidebook to the Calcium-Binding Proteins, M.R.Celio, T.Pauls, B.Schwaller, eds. (1996) Oxford University Press, Oxford. 84-85.
Summary: A brief chapter summarizing the basic properties and characteristics of squidulin.
View information in the CaBP database derived from this reference

Hebert, S.C, Brown, E.M The extracellualr calcium receptor (1995) Curr Opin Cell Biol 7, 484-492.
No information from this reference is currently stored in the database

Heidorn, D.B, Trewhalla, J. Comparison of the crystal and solution structures of calmodulin and troponin C (1988) Biochemistry 27, 909-915.
No information from this reference is currently stored in the database

Heizmann, C.W, Braun, K. Changes in Ca2+-binding proteins in human neurodegenerative disorders (1992) Trends Neurosci 15, 259-264.
Summary: Summarizes current knowledge about the role of parvalbumin and calbindin D28k in protecting the brain from damage.
No information from this reference is currently stored in the database

Heizmann, C.W, Hunziker, W. Intracellular calcium-binding proteins: more sites than insights (1991) Trends Biochem Sci 16, 98-103.
Summary: A general survey, from a mainly biological viewpoint.
No information from this reference is currently stored in the database

Helms, V. ., McCammon, J.A Kinase conformations: A computational study on the effect of ligand binding (1997) Protein Sci 6, 2336-2343.
No information from this reference is currently stored in the database

Henikoff, S., Henikoff, J.G Embedding strategies for effective use of information from multiple sequence algnments (1997) Protein Sci 6, 698-705.
No information from this reference is currently stored in the database

Hennessey, J.PN., Jr., Manavalan, P., Johnson, W.CN., Jr., Malencik, D.A, Anderson, S.R, Schimerlik, M.I, Shalitin, Y. Conformational transistions of calmodulin as studied by vacuum-UV CD (1987) Biopolymers 26, 561-571.
No information from this reference is currently stored in the database

Hermann, A., Cox, J.A Sarcoplasmic calcium-binding protein (1995) Comp Biochem Physiol B Biochem Mol Biol 111, 337-345.
View information in the CaBP database derived from this reference

Hersmdorf, C.L, Bronner, F. Vitamin D-dependent calcium-binding protein from rat kidney (1985) Biochim Biophys Acta 379, 553-561.
No information from this reference is currently stored in the database

Herzberg, O., James, M. Refined crystal structure of troponin C from turkey skeletal muscle at 2.o angstroms resolution (1988) J Mol Biol 203, 761-779.
No information from this reference is currently stored in the database

Herzberg, O., James, M.NG. Structure of the calcium regulatory muscle protein troponin-C at 2.8 A resolution (1985) Nature 313, 653-659.
No information from this reference is currently stored in the database

Herzberg, O., Moult, J., James, M.NG. A model for the Ca(2+)-induced conformational transition of troponin C (1986) J Biol Chem 261, 2638-2644.
Summary: The original paper on what became known as the HMJ model of TnC/CaM structure and function..
No information from this reference is currently stored in the database

Hessian, P.A, Edgeworth, J., Hogg, N. MRP-8 and MRP-14, two abundant Ca2+-binding proteins of neutrophils and monocytes (1993) J Leuk Biol 53, 197-204.
Summary: A fairly useful review of the current knowledge about the localization, function, and other biological characteristics of MRP-8 and -14..
View information in the CaBP database derived from this reference

Hessian, P.A, Wilkinson, L. ., Hogg, N. . The S100 family protein MRP-14 (S100A9) has homology with the contact domain of high molecular weight kininogen (1995) FEBS Lett 371, 271-275.
No information from this reference is currently stored in the database

Hidaka, H., Asano, M., Tanaka, T. Activity-structure relationship of calmodulin antagonists: napthalene derivatives (1981) Mol Pharmacol 20, 571-578.
No information from this reference is currently stored in the database

Hidaka, H., Endo, T., Kawamoto, S., Yamada, E., Umekawa, H., Tanabe, K., Hara, K. Purification and characterization of adipose tissue S-100b protein (1983) J Biol Chem 258, 2705-2709.
View information in the CaBP database derived from this reference

Hilt, D.C, Kligman, D. "The S-100 protein family: a biochemical and functional overview" in Novel Calcium Binding Proteins, C.W.Heizmann, ed. (1991) Springer-Verlag, New York. 65-103.
Summary: A slightly out of date but very comprehensive review.
View information in the CaBP database derived from this reference

Hinrichsen, R.D Calcium and calmodulin in the control of cellular behavior and motility (1993) Biochim Biophys Acta 1155, 277-293.
Summary: good review of biological functions of calmodulin.
No information from this reference is currently stored in the database

Hirschhorn, R., Aller, P., Yuan, Z.-A., Gibson, C., Baserga, R. Cell cycle specific cDNAs from mammalian cells temperature sensitive for growth (1984) Proc Natl Acad Sci USA 81, 6004-6008.
No information from this reference is currently stored in the database

Hohenester, E., Maurer, P., Hohenadl, C., Timpl, R., Jansonius, J.N, Engel, J. Structure of a novel extracellular Ca2+-binding module in BM-40 (1996) Nat Struct Biol 3, 67-73.
View information in the CaBP database derived from this reference

Hohenester, E., Maurer, P., Timpl, R. Crystal structure of a pair of follistatin-like and EF-hand calcium-binding domains in BM-40 (1997) EMBO J 16, 3778-3786.
Summary: The paper for PDB entry 1BMO.
View information in the CaBP database derived from this reference

Holm, L., Sander, C. Dictionary of recurrent domains in protein structures (1998) Proteins 33, 88-96.
Summary: Reports an automatic method for generating a "dictionary" of protein domains, and describes the dictionary resulting from analysis of a representative set of structures.
No information from this reference is currently stored in the database

Houdusse, A., Cohen, C. Structure of the regulatory domain of scallop myosin at 2 angstrom resolution: implications for regulation (1996) Structure 4, 21-32.
Summary: Structure of scallop myosin light cahins and portion of the heavy chain. Discusses unusual calcium coordination seen in the ELC. Compares with previously solved chicken skeletal myosin structure.
View information in the CaBP database derived from this reference

Houdusse, A., Love, M.L, Dominguez, R., Grabarek, Z., Cohen, C. Structures of four Ca2+-bound troponin C at 2.0 angstrom resolution: further insights into the Ca2+-switch in the calmodulin superfamily (1997) Structure 5, 1695-1711.
Summary: .
View information in the CaBP database derived from this reference

Houdusse, A., Silver, M., Cohen, C. A model of Ca(2+)-free calmodulin binding to unconventional myosins reveals how calmodulin acts as a regulatory switch (1996) Structure 4, 1475-1490.
Summary: Describes a model of calmodulin bound to unconventional myosin based on the structure of scallop myosin regulatory domain. The C-terminal domain of calmodulin is modeled in the semi-open conformation. This model is used to propose which residues in the IQ motif are essential for binding to a CaBP domain in the semi-open conformation.
No information from this reference is currently stored in the database

Howard, A., Legon, S., Spurr, N.K, Walters, J.RF. Molecular cloning and chromosomal assignment of human calbindin-D9k (1992) Biochem Biophys Res Comm 185, 663-669.
View information in the CaBP database derived from this reference

Huang, B., Watterson, D.M, Lee, V.D, Shibler, M.J Purification and characterization of a basal body-associated Ca(2+)-binding protein (1988) J Cell Biol 107, 121-131.
View information in the CaBP database derived from this reference

Hunter, M.J, Chazin, W.J High level expression and dimer characterization of the S100 EF-hand proteins, migration inhibitory factor-related proteins 8 and 14 (1998) J Biol Chem 273, 12427-12435.
View information in the CaBP database derived from this reference

Huque, M.E, Vogel, H.J Carbon-13 NMR studies of the lysine side chains of calmodulin and its proteolytic fragments (1993) J Prot Chem 12, 695-707.
No information from this reference is currently stored in the database

Hutnik, C.ML., MacManus, J.P, Banville, D., Szabo, A.G Comparison of metal ion-induced conformational changes in parvalbumin and ocomodulin as probed by the intrinsic fluorescence of tryptophan 102 (1990) J Biol Chem 265, 11456-11464.
No information from this reference is currently stored in the database

Hutnik, C.ML., MacManus, J.P, Banville, D., Szabo, A.G Metal-induced changes in the fluorescence properties of tyrosine and tryptophan site-specific mutants of oncomodulin (1991) Biochemistry 30, 7652-7660.
No information from this reference is currently stored in the database

Hutnik, C.ML., MacManus, J.P, Szabo, A.G A calcium-specific conformationsl response of parvalbumin (1990) Biochemistry 29, 7318-7328.
No information from this reference is currently stored in the database

Iida, S., Potter, J.D Calcium binding to calmodulin. Cooperativity of the calcium-binding sites (1986) J Biochem 99, 1765-1772.
No information from this reference is currently stored in the database

Ikura, M. Calcium binding and conformational response in EF-hand proteins (1996) Trends Biochem Sci 21, 14-17.
Summary: Introduction to the differences between EF hand proteins with "sensor" and "buffer" functions.
No information from this reference is currently stored in the database

Ikura, M., Clore, G.M, Gronenborn, A.M, Zhu, G., Klee, C.B, Bax, A. Solution structure of a calmodulin-target peptide complex by multidimensional NMR (1992) Science 256, 632-638.
View information in the CaBP database derived from this reference

Ikura, M., Kay, L.E, Bax, A. A novel approach for sequential assignment of 1H,13C and 15N spectra of larger proteins: Heteronuclear triple-resonance three-dimensional NMR spectroscopy. Application to calmodulin (1990) Biochemistry 29, 4659-466.
No information from this reference is currently stored in the database

Ikura, M., Spera, S., Barbato, G., Kay, L.E, Krinks, M., Bax, A. Secondary structure and side-chain 1H and 13C resonance assignments of calmodulin in solution by heteronuclear multidimensional NMR spectroscopy (1991) Biochemistry 30, 9216-9228.
No information from this reference is currently stored in the database

Ilg, E.C, Schafer, B.W, Heizmann, C.W Expression pattern of S100 calcium-binding proteins in human tumors (1996) Int J Cancer 68, 325-332.
No information from this reference is currently stored in the database

Inaguma, Y., Kurobe, N., Shinohara, H., Kato, K. Sensitive immunoassay for rat parvalbumin: tissue distribution and developmental changes (1991) Biochim Biophys Acta 1075, 68-74.
View information in the CaBP database derived from this reference

Islam, S.A, Sternberg, M.JE. A relational database of protein structures designed for flexible enquires about conformation (1989) Protein Eng 2, 431-442.
Summary: Describes the design and implementation of a relational database containing a range of information about crystal structures.
No information from this reference is currently stored in the database

Jackson, A.E, Puett, D. Binding of trifluoperazine and fluorene-containing compounds to calmodulin and adducts (1986) Biochem Pharmacol 35, 4395-4400.
No information from this reference is currently stored in the database

Janin, J., Wodak, S. Conformation of amino acid side-chains in proteins (1978) J Mol Biol 125, 357-386.
No information from this reference is currently stored in the database

Jansco, A., Szent-Gyorgyi, A.G Regulation of scallop myosin by the regulatory light chain depends on a single glycine residue (1994) Proc Natl Acad Sci USA 91, 8762-8766.
No information from this reference is currently stored in the database

Jiang, H., Shah, S., Hilt, D.C Organization, sequence, and expression of the murine S100B gene (1993) J Biol Chem 268, 20502-20511.
View information in the CaBP database derived from this reference

Johansson, C., Brodin, P., Grundstrom, T., Forsen, S., Drakenberg, T. Mutation of the pseudo-EF hand of calbindin D9k into a normal EF hand: biophysical studies (1991) Eur J Biochem 202, 1283-1290.
Summary: A series of mutants were made in an attempt to turn the pseudo-EF hand loop into a canonical one. One mutant (A14 removed+A15D+P20G+N21 removed) seems to do this, but cooperativity is lost..
View information in the CaBP database derived from this reference

Johansson, C., Brodin, P., Grundstrom, T., Thulin, E., Forsen, S., Drakenberg, T. Biophysical studies of engineered mutant proteins based on calbindin D9k modified in the pseudo EF-hand (1990) Eur J Biochem 187, 455-460.
No information from this reference is currently stored in the database

Johansson, C., Ullner, M., Drakenberg, T. The solution structures of mutant calbindin D9kıs, as determined by NMR, show that the calcium-binding site can adopt different folds. (1993) Biochemistry 32, 8429-8438.
Summary: Report of the NMR structure of a mutant calbindin in which the N terminal binding loop is converted from a pseudo-EF hand to a canonical fold. The mutant is A14 removed+A15D+P20G+N21 removed+P43M. The calcium-loaded state of this mutant is found to have the same global fold (³closed²) as the wildtype protein. The proton assignments indicate that the mutant A14 removed+P20G+N21 removed also adopts the canonical fold..
View information in the CaBP database derived from this reference

Joyal, J.L, Annan, R.A, Ho, Y.D, Huddleston, M.E, Carr, S.A, Hart, M.J, Sacks, D.B Calmodulin modulates the interaction between IQGAP1 and Cdc42:Identification of IQGAP1 by nanoelectrospray tandem mass spectroscopy (1997) J Biol Chem 272, 15419-15425.
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Joyal, J.L, Burks, D.J, Pons, S., Matter, W.F, Vlahos, C.J, White, M.F, Sacks, D.B Calmodulin activates phosphatidylinositol 3-kinase (1997) J Biol Chem 272, 28183-28186.
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Julenius, K., Thulin, E., Linse, S., Finn, B.E Hydrophobic core substitutions in calbindin D9k: effects on stability and structure (1998) Biochemistry 37, 8915-8925.
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Kahn, R., Fourme, R., Bosshard, R., Chiadmi, M., Risler, J.L, Dideberg, O., Wery, J.P Crystal structure study of Opsanus tau parvalbumin by multiwavelength anomalous diffraction (1985) FEBS Lett 179, 133-137.
Summary: Tb is substituted for Ca.
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Kakalis, L.T, Kennedy, M., Sikkin, R., Rusnak, F., Armitage, I.M Characterization of the calcium-binding sites of calcineurin B (1995) FEBS Lett 362, 55-58.
No information from this reference is currently stored in the database

Kalabokis, V.N, O'Neall-Hennessey, E., Szent-Gyorgyi, A.G Regulatory domains of myosins: influence of heavy chain on Ca2+-binding (1994) J Musc Res Cell Motil 15, 547-553.
No information from this reference is currently stored in the database

Kaptein, R., Zuiderweg, E.RP., Scheek, R.M, Boelens, R., vanGunsteren, W.F A protein structure from nuclear magnetic resonance data. Lac repressor headpiece (1985) J Mol Biol 182, 179-182.
No information from this reference is currently stored in the database

Karplus, P.A Hydrophobicity regained (1997) Protein Sci 6, 1302-1307.
Summary: An examination of the true meaning of studies of the partition of amino acids into non-aqueous solvents, and an explanation of a more accurate hydrophobicity scale.
No information from this reference is currently stored in the database

Kataoka, M., Head, J.F, Seaton, B.A, Engelman, D.M Melittin binding causes a large calcium-dependent conformational change in calmodulin (1989) Proc Natl Acad Sci USA 86, 6944-6948.
No information from this reference is currently stored in the database

Kawasaki, H., Kretsinger, R.H Calcium-binding Proteins 1:EF-hands (1995) Protein Profile 2, 305-490.
No information from this reference is currently stored in the database

Kay, L.E, Ikura, M., Zhu, G., Bax, A. Four-dimensional heteronuclear triple-resonance NMR of isotopically enriched proteins for sequential assignment of backbone atoms (1991) J Magn Reson 91, 422-428.
No information from this reference is currently stored in the database

Kay, L.E, Torchia, D., Bax, A. Backbone dynamics of proteins as studied by 15N inverse detected heteronuclear NMR spectroscopy: application to staphylococcal nuclease (1989) Biochemistry 28, 8972-8979.
No information from this reference is currently stored in the database

Kelly, J.W Amyloid fibril formation and protein misassembly: a structural quest for insights into amyloid and prion disease (1997) Structure 5, 595-600.
No information from this reference is currently stored in the database

Kennedy, M.T, Brockman, H., Rusnak, F. Contributions of myristoylation to calcineurin structure/function (1996) J Biol Chem 271, 26517-26521.
No information from this reference is currently stored in the database

Kesvatera, T., Jonsson, B., Thulin, E., Linse, S. Binding of Ca(2+) to calbindin D9k: structural stability and function at high salt concentration (1994) Biochemistry 33, 14170-14176.
Summary: Calbindin retains its structure and ability to bind calcium in 1M KCl. Studies with high salt and charge-neutralizing mutations indicate that cooperativity of calcium binding is greatly influenced by electrostatics..
No information from this reference is currently stored in the database

Kilby, P.M, Van Eldik, L.J, Roberts, G.CK. The solution structure of the bovine S100B protein dimer in the calcium-free state (1996) Structure 4, 1041-1052.
Summary: The paper for PDB entry 1CFP.
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Kilhoffer, M.-C., Kubina, M., Travers, F., Haiech, J. Use of engineered proteins with internal tryptophan reporter groups and perturbation techniques to probe the mechanism of ligan-protein interactions: investigation of the mechanism of calcium-binding to calmodulin (1992) Biochemistry 31, 8098-8106.
No information from this reference is currently stored in the database

Kindy, M.S, Brown, K.E, Sonnenshein, G.E Regulation of expression of the growth-state-related genes 2F1 and 2A9 during entruy of quiescent smooth muscle cells into the cell cycle (1991) J Cell Biochem 46, 345-350.
No information from this reference is currently stored in the database

Kirkpatrick, S., Gelatt, C.DN., Jr., Vecchi, M.P Optimization by simulated annealing (1983) Science 220, 671-680.
No information from this reference is currently stored in the database

Kissinger, C.R, Parge, H.E, Knighton, D.R, Lewis, C.T, Pelletier, L.A, Tempczyk, A., Kalish, V.J, Tucker, K.D, Showalter, R.E, Moomaw, E.W, Gastinel, L.N, Habuka, N., Chen, X., Maldonado, F., Barker, J.E, Bacquet, R., Villafranca, J.E Crystal structures of human calcineurin and the human FKBp12-FK506-calcineurin complex (1995) Nature 378, 641-644.
Summary: The paper for PDB entry 1AUI.
No information from this reference is currently stored in the database

Klee, C.B, Draetta, G.F, Hubbard, M.J Calcineurin (1988) Adv Enzymol 61, 149-200.
No information from this reference is currently stored in the database

Klee, C.B, Krinks, M.H Purification of cyclic 3ı,5ı-nucleotide phosphodiesterase inhibitory protein by affinity chromotography on activator protein coupled to sepharose (1978) Biochemistry 17, 120-126.
No information from this reference is currently stored in the database

Klein, J.R, Hoon, D.SB., Nangauyan, J., Okun, E., Cochran, A.J S-100 protein stimulates cellular proliferation (1989) Cancer Immunol Immunother 29, 133-138.
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Klempt, M., Melkonyan, H., Nacken, W., Wiesmann, D., Holtkemper, U., Sorg, C. The heterodimer of Ca2+-binding proteins MRP8 and MRP14 binds arachidonic acid (1997) FEBS Lett 408, 81-84.
Summary: Presents evidence that the MRP8/MRP14 heterodimer interactic with arachidomic acid in a calcium-dependent manner..
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Klenchin, V.A, Calvert, P.D, Bownds, M.D Inhibition of rhodopsin kinase by recoverin (1995) J Biol Chem 270, 16147-16152.
Summary: This paper reports on the inhibition of phophorylation of rhodopsin by calcium-loaded recoverin, most likely by direct inhibition of rhodopsin kinase. Extrapolation of in vitro measurements of the calcium affinity of recoverin to physiological conditions indicates that the inhibition of rhodopsin kinase by calcium-loaded recoverin is physiologically relevent..
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Kordel, J., Forsen, S., Drakenberg, T., Chazin, W.J The rate and structural consequences of proline cis-trans isomerization in calbindin D9k: NMR studies of the minor (Cis-Pro43) isoform and the Pro43Gly mutant (1990) Biochemistry 29, 4000-4009.
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Kordel, J., Pearlman, D.A, Chazin, W.J Protein solution structure calculations in solution: Solvated molecular dynamics refinement of calbindin D9k (1997) J Biomol NMR 10, 231-243.
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Kordel, J., Skelton, N., Akke, M., Chazin, W.J High resolution solution structure of calcium-loaded calbindin D9k (1993) J Mol Biol 231, 711-734.
Summary: Presents the solution structure of calcium loaded calbindin and makes a useful comparison with the crystal structure.
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Kordel, J., Skelton, N.J, Akke, M., Palmer, A.G, Chazin, W.J Backbone dynamics of calcium-loaded calbindin D9k studied by two-dimensional proton-detected 15N NMR spectroscopy (1992) Biochemistry 31, 4856-4866.
No information from this reference is currently stored in the database

Kragelund, B.B, Jonsson, M., Bifulco, G., Chazin, W.J, Nilsson, H., Finn, B.E, Linse, S. Hydrophobic core substitution in calbindin D9k: Effects on Ca2+ binding and dissociation (1998) Biochemistry 37, 8926-8937.
View information in the CaBP database derived from this reference

Krebs, J., Quadroni, M., VanEdlik, L.J Dance of the Dimers (1995) Nat Struct Biol 2, 711-714.
No information from this reference is currently stored in the database

Kretsinger, R.H EF-hands reach out (1996) Nat Struct Biol 3, 12-15.
No information from this reference is currently stored in the database

Kretsinger, R.H, Nockolds, C.E Carp muscle calcium-binding protein: II. structure determination and general description (1973) J Biol Chem 248, 3313-3326.
No information from this reference is currently stored in the database

Krieger, C., Lanius, R.A, Pelech, S.L, Shaw, C.A Amyotrophic lateral sclerosis: the involvement of intracellular Ca(2+) and protein kinase C (1996) Trends Pharmacol Sci 17, 114-120.
No information from this reference is currently stored in the database

Kube, E. ., Becker, T. ., Weber, K. ., Gerke, V. . Protein-protein interaction studied by site-directed mutagenesis. Characterization of the annexin II-binding site on p11, a member of the S100 protein family (1992) J Biol Chem 267, 14175-14182.
No information from this reference is currently stored in the database

Kuboniwa, H., Tjandra, N., Grzesiek, S., Ren, H., Klee, C.B, Bax, A. Solution structure of calcium-free calmodulin (1995) Nat Struct Biol 2, 768-776.
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Kumar, V.D, Lee, L., Edwards, B.FP. Refined crystal structure of calcium-liganded carp parvalbumin 4.25 at 1.5-angstrom resolution (1990) Biochemistry 29, 1404-1412.
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Kumar, V.D, Lee, L., Edwards, B.FP. Refined crystal structure of ytterbium-substituted carp parvalbumin 4.25 at 1.5 angstrom, and its comparison with the native and cadmium-substituted structures (1991) FEBS Lett 283, 311-316.
No information from this reference is currently stored in the database

Kuznicki, J., Filipek, A. Purification and properties of a novel Ca2+-binding protein (10.5 kDa) from Ehrlich ascites tumor cells (1987) Biochem J 247, 663-667.
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Lackmann, M. ., Rajasekariah, P. ., Iismaa, S.E, Jones, G. ., Cornish, C.J, Hu, S. ., Simpson, R.J, Moritz, R.L, Geczy, C.L Identification of a chemotactic domain of the pro-inflammatory S100 protein CP-10 (1993) J Immunol 150, 1981-2991.
No information from this reference is currently stored in the database

Lackmann, M., Cornish, C.J, Simpson, R.J, Moritz, R.L, Geczy, C.L Purification and structural analysis of a murine chemotactic cytokine (CP-10) with sequence homology to S100 proteins (1992) J Biol Chem 267, 7499-7504.
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Lakshmi, M.S, Parker, C., Shernet, G.V Metastasis associated MTS1 and NM23 genes affect tubulin polymerisation in B16 melanomas: a possible mechanism of their regulation of metastatic behaviour of tumors (1993) Anticancer Res 13, 299-304.
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Landar, A., Caddell, G., Chessher, J., Zimmer, D.B Identification of an S100A1/S100B target protein: phosphoglucomutase (1996) Cell Calcium 20, 279-285.
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Lane, T.F, Sage, E.H The biology of SPARC, a protein that modulates cell-matrix interactions (1994) FASEB J 6, 163-173.
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Lannrgren, J., Elzinga, G., Stienen, G.J Force relaxation, labile heat and parvalbumin content of skeletal muscle fibres of Xenopus laevis (1993) J Physiol 463, 123-140.
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LaPorte, D.C, Wierman, B.M, Storm, D.R Calcium-induced exposure of a hydrophobic surface on calmodulin (1980) Biochemistry 19, 3814-3819.
No information from this reference is currently stored in the database

Lavorgna, G., Boncinelli, E., Wagner, A., Werner, T. Detection of potential target genes in silico? (1998) Trends Genet 14, 375-376.
No information from this reference is currently stored in the database

Lazar, G.A, Desjarlais, J.R, Handel, T.M De novo design of the hydrophobic core of ubiquitin (1997) Protein Sci 6, 1167-1178.
Summary: Describes a program for predicting which sequences in a protein core will result in a stable protein with unique tertiary structure.
No information from this reference is currently stored in the database

Lee, B., Vasmatzis, G. Stabilization of protein strucutres (1997) Curr Opin Biotech 8, 423-428.
Summary: A brief, useful review of recent protein engineering studies about the role of specif types of interactions in protein stability.
No information from this reference is currently stored in the database

Lee, S.-J., Stull, J.T Calmodulin-dependent regulation of inducible and neuronal nitric-oxide synthase (1998) J Biol Chem 273, 27430-27437.
No information from this reference is currently stored in the database

Lee, S.W, Tomasetto, C., Swissheln, L., Keyomarsi, K., Sager, R. Down-regulation of a member of the S100 gene family in mammary carcinoma cells and reexpression by azadeoxycytidine treatment (1992) Proc Natl Acad Sci USA 89, 2504-2508.
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Lee, V.D, Huang, B. Molecular cloning and centrosomal localization of human caltractin (1993) Proc Natl Acad Sci USA 90, 11039-11043.
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Lee, V.D, Stapleton, M., Huang, B. Genomic structure of Chlamydomonas caltractin: evidence for intron insertion suggests a probable genealogy for the EF-hand superfamily of proteins (1991) J Mol Biol 221, 175-191.
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Lee, W. ., Revington, M.J, Arrowsmith, C. ., Kay, L.E A pulsed field gradient isotope-filtered 3D 13C HMQC-NOESY experiment for extracting intermolecular NOE contacts in molecular complexes. (1994) FEBS Lett 350, 87-90.
No information from this reference is currently stored in the database

Lee, Y.C, J Wolff, J. . Two opposing effects of calmodulin on microtubule assembly depend on the presence of microtubule-associated proteins (1982) J Biol Chem 259, 1226-1230.
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Levin, R.M, Weiss, B. Specificity of the binding of trifluoperazine to the calcium-dependent activator of phosphodiesterase and to a series of other calcium-binding proteins (1978) Biochim Biophys Acta 540, 197-204.
No information from this reference is currently stored in the database

Levy, Y.Y, Lai, E.Y, Remillard, S.P, Heintzelman, M.B, Chandler, F. Centrin is a conserved protein that forms diverse associations with centrioles and MTOCs in Naegleria and other organisms (1996) Cell Motil and Cytoskel 33, 298-323.
No information from this reference is currently stored in the database

Li, M.X, Gagne, S.M, Spyracopoulos, L., Loks, C.PA., Audette, G., Chandra, M., Solaro, R.J, Smillie, L.B, Sykes, B.D NMR studies of Ca2+ binding to the regulatory domain of cardiac and E41A skeletal muscle troponin C reveal the importance of site I to energetics of the induced structural change (1997) Biochemistry 36, 12519-12525.
No information from this reference is currently stored in the database

Li, M.X, Gagne, S.M, Tsuda, S., Kay, C.M, Smillie, L.B, Sykes, B.D Calcium binding to the regulatory N-domain of skeletal muscle troponin C occurs in a stepwise manner (1995) Biochemistry 34, 8330-8340.
No information from this reference is currently stored in the database

Liang, S., Fuhrman, S., Somogyi, R. REVEAL, a general reverse engineering algorithm for inference of genetic network architectures (1998) Pacific Symposium on Biocomputing 3, 18-29.
No information from this reference is currently stored in the database

Liemann, S., Lewit-Bentley, A. Annexins: a novel family of calcium- and membrane-binding proteins in search of a function (1995) Structure 3, 233-237.
No information from this reference is currently stored in the database

Lin, G.-d., Chattopdhyaya, D., Masatoshi, M., Wang, K.KW., Carson, M., Jin, L., Yuen, P.-w., Takano, E., Hatanaka, M., DeLucas, L.J, Narayana, S.VL. Crystal structure of calcium bound domain VI of calpain at 1.9 A resolution and its role in enzyme assembly, regulation, and inhibitor binding (1997) Nat Struct Biol 4, 539-547.
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Lin, X., Krudy, G.A, Howarth, J., Brito, R.MM., Rosevear, P.R, Putkey, J.A Assignment and calcium dependence of methionyl (e)C and (e)H resonances in cardiac troponin C (1994) Biochemistry 33, 14434-14442.
No information from this reference is currently stored in the database

Linse, S., Brodin, P., Drakenberg, T., Thulin, E., Sellers, P., Elmden, K., Grundstrom, T., Forsen, S. Structure-function relationships in EF-Hand Ca(2+)-binding proteins. Protein engineering and biophysical studies of calbindin D9k (1987) Biochemistry 26, 6723-6735.
Summary: The mutation of Y13F has no effect on the cooperativity of calcium-binding, although it does affect the macroscopic binding constants..
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Linse, S., Bylsma, N.R, Drakenberg, T., Sellers, P., Forsen, S., Thulin, E. A calbindin D9k mutant with reduced calcium affinity and enhanced cooperativity. Metal ion binding, stability, and structural studies (1994) Biochemistry 33, 12478-12486.
Summary: Mutating glu 60 to asp decreases calcium affinity and increases cooperativity of binding. The decrease in affinity is thought to occur because the shorter asp side chain has a weaker hydrogen bond to the calcium-liganding water molecule thatn the glu side chain had. The reason for the increase in cooperativity is less apparent..
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Linse, S., Forsen, S. Determinants that govern high-affinity calcium binding (1995) Adv Second Messenger Phosphoprotein Res 30, 89-151.
Summary: Excellent review of what is known about calcium affinity in EF Hand proteins. Also includes information about other types of calcium binding proteins. Includes a clear and concise background on the physical chemistry of affinity and cooperativity..
No information from this reference is currently stored in the database

Linse, S., Helmersson, A., Forsen, S. Calcium binding to calmodulin and its globular domains (1991) J Biol Chem 266, 8050-8054.
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Linse, S., Johansson, C., Brodin, P., Grundstrom, T., Drakenberg, T., Forsen, S. Electrostatic contributions to the binding of Ca(2+) in calbindin D9k (1991) Biochemistry 30, 154-183.
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Linse, S., Jonsson, B., Chazin, W.J The effect of protein concentration on ion binding (1995) Proc Natl Acad Sci USA 92, 4748-4752.
No information from this reference is currently stored in the database

Linse, S., Teleman, O., Torbjorn, D. Ca(2+) binding to calbindin D9k strongly affects backbone dynamics: measurements of exchange rates of individual amide protons using (1)H-NMR (1990) Biochemistry 29, 5925-5934.
Summary: Reports the measurement of exchange rates for all amide hydrogens in the calcium-loaded form of calbindin and about one-half pf the amide hydrogens in the apo form. In general, the calcium-loaded form has slower exchange..
No information from this reference is currently stored in the database

Linse, S., Thulin, E., Gifford, L.K, Radzewsky, D., Hagan, J., Wilk, R.R, Akerfeldt, K.S Domain organization of calbindin D28k as determined from the association of six synthetic EF-hand fragments (1997) Protein Sci 6, 2385-2396.
Summary: Using peptides of the individual EF-hands in calbindin D28k and a variety of biophysical techniques, the authors present strong evidence that all six EF-hands of calbindin D28k are part of a single domain.
No information from this reference is currently stored in the database

Linse, S., Thulin, E., Selllers, P. Disulfide bonds in homo- and heterodimers of EF-hand subdomains of calbindin D9k: stability, calcium binding, and NMR studies (1993) Protein Sci 2, 985-1000.
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Lipari, F. ., Herscovics, A. . Calcium binding to the class I alpha-1,2,-Mannosidase from Saccharomyces cerevisiae occurs outside the EF hand motif (1999) Biochemistry 38, 1111-1118.
No information from this reference is currently stored in the database

Lipari, G., Szabo, A. Model-free approach to the interpretation of nuclear magnetic resonance relaxation in macromolecules. 1. Theory and range of validity (1982) J Am Chem Soc 104, 4546-4559.
No information from this reference is currently stored in the database

Lipscomb, L.A, Gassner, N.C, Snow, S.D, Eldridge, A.M, Baasa, W.A, Drew, D.L, Matthews, B.W Context-dependent protein stabilization by methionine-to-leucine substitution shown in T4 lysozyme (1998) Protein Sci 7, 765-773.
Summary: A report on the effects of Met to Leu and Met to Lys mutations in T4 lysozyme. Discusses the possibility of predicting which Met to Leu mutation will be stabilizing.
No information from this reference is currently stored in the database

Liu, H. ., Spielmann, P. ., Ulyanov, N.B, Wemmer, D.E, James, T.L Interproton distance bounds from 2D NOE intensities: effect of experimental noise and peak integration errors (1995) J Biomol NMR 6, 390-402.
No information from this reference is currently stored in the database

Liu, J., Farmer, J.DN., Jr., Lane, W.S, Firedman, J., Weissman, I., Schreiber, S.L Calcineurin is a common target of cyclophilin-cyclosporinA and FKBP-FK506 complexes (1991) Cell 66, 807-815.
No information from this reference is currently stored in the database

Liu, Y., Storm, D.R Regulation of free calmodulin levels by neuromodulin: neuron growth and regeneration (1990) Trends Pharmacol Sci 11, 107-111.
Summary: Discussion focuses on the biochemical properties and tissue-specificity of neuromodulin. The interaction of neuromodulin with CaM is also discussed, and a biochemical model is proposed to explain the significance of this interaction..
No information from this reference is currently stored in the database

Loll, P.J, Lattmam, E.E The crystal structure of the ternary complex of Staphylococcal nuclease, Ca2+, and the inhibitor pdTp, refined at 1.65 angstroms (1989) Proteins 5, 183-201.
No information from this reference is currently stored in the database

Loomans, H.J, Hahn, B.L, Li, Q.-L., Phadnis, S.H, Sohnle, P.G Histidine-based zinc-binding sequences and the antimicrobial activity of calprotectin (1998) J Infect Dis 177, 812-814.
No information from this reference is currently stored in the database

Lowenstein, C.J, Snyder, S.H Nitric oxide, a novel biologic messenger (1992) Cell 70, 705-707.
No information from this reference is currently stored in the database

Luan-Rilliet, Y., Milos, M., Cox, J.A Thermodynamics of cation binding to Nereis sarcoplasmic calcium-binding protein (1992) Eur J Biochem 208, 133-138.
No information from this reference is currently stored in the database

Lukas, T.J, Burgess, W.H, Prendergast, F.G, Lau, W., Watterson, D.M Calmodulin binding domains: characterization of a phosphorylation and calmodulin binding site from myosin light chain kinase (1986) Biochemistry 25, 1458-1464.
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Lukas, T.J, Collinge, M., Haiech, J., Watterson, D.M Gain of function mutations for yeast calmodulin and calcium dependent regulation of protein kinase activity (1994) Biochim Biophys Acta 1223, 341-347.
No information from this reference is currently stored in the database

Lyall, A. Bioinformatics in the pharmaceutical industry (1996) Trends Biotech 14, 308-312.
No information from this reference is currently stored in the database

Lytton, J., Nigam, S.K Intracellular calcium: molecules and pools (1992) Curr Opin Cell Biol 4, 220-